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Items: 1 to 50 of 90

1.

Nutrition interventions for healthy ageing across the lifespan: a conference report.

Kalache A, de Hoogh AI, Howlett SE, Kennedy B, Eggersdorfer M, Marsman DS, Shao A, Griffiths JC.

Eur J Nutr. 2019 Jun;58(Suppl 1):1-11. doi: 10.1007/s00394-019-02027-z.

2.

Development of a consensus approach for botanical safety evaluation - A roundtable report.

Galli CL, Walker NJ, Oberlies NH, Roe AL, Edwards J, Fitzpatrick S, Griffiths JC, Hayes AW, Mahony C, Marsman DS, O'Keeffe L.

Toxicol Lett. 2019 Oct 10;314:10-17. doi: 10.1016/j.toxlet.2019.05.008. Epub 2019 May 10. Review.

PMID:
31082523
3.

Industry Actions to Address Quality Issues for Dietary Supplements, Botanicals, and Other Natural Products.

Shenkar J, Griffiths JC.

Clin Pharmacol Ther. 2018 Sep;104(3):423-425. doi: 10.1002/cpt.1119. Epub 2018 Aug 17.

PMID:
30120783
4.

Healthy ageing: the natural consequences of good nutrition-a conference report.

Marsman D, Belsky DW, Gregori D, Johnson MA, Low Dog T, Meydani S, Pigat S, Sadana R, Shao A, Griffiths JC.

Eur J Nutr. 2018 Jun;57(Suppl 2):15-34. doi: 10.1007/s00394-018-1723-0.

5.

Dietary guidance for lutein: consideration for intake recommendations is scientifically supported.

Ranard KM, Jeon S, Mohn ES, Griffiths JC, Johnson EJ, Erdman JW Jr.

Eur J Nutr. 2017 Dec;56(Suppl 3):37-42. doi: 10.1007/s00394-017-1580-2. Review.

6.

Optimal nutrition and the ever-changing dietary landscape: a conference report.

Shao A, Drewnowski A, Willcox DC, Krämer L, Lausted C, Eggersdorfer M, Mathers J, Bell JD, Randolph RK, Witkamp R, Griffiths JC.

Eur J Nutr. 2017 May;56(Suppl 1):1-21. doi: 10.1007/s00394-017-1460-9.

7.

Bioactive nutrients - Time for tolerable upper intake levels to address safety.

Yates AA, Erdman JW Jr, Shao A, Dolan LC, Griffiths JC.

Regul Toxicol Pharmacol. 2017 Mar;84:94-101. doi: 10.1016/j.yrtph.2017.01.002. Epub 2017 Jan 18. Review.

8.

The Importance of Quality Specifications in Safety Assessments of Amino Acids: The Cases of l-Tryptophan and l-Citrulline.

Oketch-Rabah HA, Roe AL, Gurley BJ, Griffiths JC, Giancaspro GI.

J Nutr. 2016 Dec;146(12):2643S-2651S. Epub 2016 Nov 9. Review.

PMID:
27934657
9.

Nutrient reference value: non-communicable disease endpoints--a conference report.

Lupton JR, Blumberg JB, L'Abbe M, LeDoux M, Rice HB, von Schacky C, Yaktine A, Griffiths JC.

Eur J Nutr. 2016 Mar;55 Suppl 1:S1-10. doi: 10.1007/s00394-016-1195-z.

10.

Assessing Natural Product-Drug Interactions: An End-to-End Safety Framework.

Roe AL, Paine MF, Gurley BJ, Brouwer KR, Jordan S, Griffiths JC.

Regul Toxicol Pharmacol. 2016 Apr;76:1-6. doi: 10.1016/j.yrtph.2016.01.004. Epub 2016 Jan 9.

PMID:
26776752
11.

A quality dietary supplement: before you start and after it's marketed--a conference report.

LeDoux MA, Appelhans KR, Braun LA, Dziedziczak D, Jennings S, Liu L, Osiecki H, Wyszumiala E, Griffiths JC.

Eur J Nutr. 2015 Jan;54 Suppl 1:S1-8. doi: 10.1007/s00394-014-0827-4.

12.

Exploring the benefits and challenges of establishing a DRI-like process for bioactives.

Lupton JR, Atkinson SA, Chang N, Fraga CG, Levy J, Messina M, Richardson DP, van Ommen B, Yang Y, Griffiths JC, Hathcock J.

Eur J Nutr. 2014 Apr;53 Suppl 1:1-9. doi: 10.1007/s00394-014-0666-3. Review.

13.

Nutrient reference values for bioactives: new approaches needed? A conference report.

Biesalski HK, Erdman JW Jr, Hathcock J, Ellwood K, Beatty S, Johnson E, Marchioli R, Lauritzen L, Rice HB, Shao A, Griffiths JC.

Eur J Nutr. 2013 Apr;52 Suppl 1:1-9. doi: 10.1007/s00394-013-0503-0.

14.

Adulteration of drugs and foods: compendial approaches to lowering risk.

Abernethy DR, Sheehan C, Griffiths JC, Williams RL; United States Pharmacopeial Convention Council of Experts Excipients and Food Ingredient Expert Committees.

Clin Pharmacol Ther. 2009 Apr;85(4):444-7. doi: 10.1038/clpt.2008.88. Epub 2008 May 7. Review. No abstract available.

PMID:
18463621
15.

Genotoxicity studies on Sel-Plex, a standardized, registered high-selenium yeast.

Griffiths JC, Matulka RA, Power R.

Int J Toxicol. 2006 Nov-Dec;25(6):477-85.

PMID:
17132606
16.

Acute and subchronic toxicity studies on Sel-Plex, a standardized, registered high-selenium yeast.

Griffiths JC, Matulka RA, Power R.

Int J Toxicol. 2006 Nov-Dec;25(6):465-76.

PMID:
17132605
17.

Lack of oral embryotoxicity/teratogenicity with D-ribose in Wistar rats.

Griffiths JC, Borzelleca JF, St Cyr J.

Food Chem Toxicol. 2007 Mar;45(3):388-95. Epub 2006 Sep 8.

PMID:
17049708
18.

Sub-chronic (13-week) oral toxicity study with D-ribose in Wistar rats.

Griffiths JC, Borzelleca JF, St Cyr J.

Food Chem Toxicol. 2007 Jan;45(1):144-52. Epub 2006 Aug 30.

PMID:
17011102
19.

Toxicology and pharmacology of sodium ricinoleate.

Burdock GA, Carabin IG, Griffiths JC.

Food Chem Toxicol. 2006 Oct;44(10):1689-98. Epub 2006 May 26. Review.

PMID:
16831502
20.

The importance of GRAS to the functional food and nutraceutical industries.

Burdock GA, Carabin IG, Griffiths JC.

Toxicology. 2006 Apr 3;221(1):17-27. Epub 2006 Feb 17.

PMID:
16483705
21.

Safety evaluation of a natural tomato oleoresin extract derived from food-processing tomatoes.

Matulka RA, Hood AM, Griffiths JC.

Regul Toxicol Pharmacol. 2004 Jun;39(3):390-402.

PMID:
15135216
22.

Safety of ephedra: lessons learned.

Soni MG, Carabin IG, Griffiths JC, Burdock GA.

Toxicol Lett. 2004 Apr 15;150(1):97-110. Review.

PMID:
15068827
23.

Chronic toxicity and oncogenicity of N-methylpyrrolidone (NMP) in rats and mice by dietary administration.

Malley LA, Kennedy GL, Elliott GS, Slone TW, Mellert W, Deckardt K, Kuttler K, Hildebrand B, Banton MI, Parod RJ, Griffiths JC.

Drug Chem Toxicol. 2001 Nov;24(4):315-38.

PMID:
11665646
24.

90-day subchronic toxicity study in rats and mice fed N-methylpyrrolidone (NMP) including neurotoxicity evaluation in rats.

Malley LA, Kennedy GL, Elliott GS, Slone TW, Mellert W, Deckardt K, Gembardt C, Hildebrand B, Parod RJ, McCarthy TJ, Griffiths JC.

Drug Chem Toxicol. 1999 Aug;22(3):455-80.

PMID:
10445158
25.

Assessment of Herpesvirus saimiri as a potential human gene therapy vector.

Stevenson AJ, Cooper M, Griffiths JC, Gibson PC, Whitehouse A, Jones EF, Markham AF, Kinsey SE, Meredith DM.

J Med Virol. 1999 Mar;57(3):269-77.

PMID:
10022799
27.

Carcinogenic risks of inorganic arsenic in perspective.

Byrd DM, Roegner ML, Griffiths JC, Lamm SH, Grumski KS, Wilson R, Lai S.

Int Arch Occup Environ Health. 1996;68(6):484-94.

PMID:
8891790
28.

A transient three-plasmid expression system for the production of high titer retroviral vectors.

Soneoka Y, Cannon PM, Ramsdale EE, Griffiths JC, Romano G, Kingsman SM, Kingsman AJ.

Nucleic Acids Res. 1995 Feb 25;23(4):628-33.

29.

Alkaline phosphatase. Pandora's box opens.

Griffiths JC.

Arch Pathol Lab Med. 1994 Sep;118(9):868-9. No abstract available.

PMID:
7915899
30.

Acquired Brown's syndrome.

Barnett AJ, Griffiths JC, West RH.

Ann Rheum Dis. 1993 Nov;52(11):835. No abstract available.

31.
32.

Induction of HIV-specific cytotoxic T lymphocytes in vivo with hybrid HIV-1 V3:Ty-virus-like particles.

Layton GT, Harris SJ, Gearing AJ, Hill-Perkins M, Cole JS, Griffiths JC, Burns NR, Kingsman AJ, Adams SE.

J Immunol. 1993 Jul 15;151(2):1097-107.

PMID:
8335892
33.

Hybrid human immunodeficiency virus Gag particles as an antigen carrier system: induction of cytotoxic T-cell and humoral responses by a Gag:V3 fusion.

Griffiths JC, Harris SJ, Layton GT, Berrie EL, French TJ, Burns NR, Adams SE, Kingsman AJ.

J Virol. 1993 Jun;67(6):3191-8.

34.

Pharmacokinetic data in the evaluation of the safety of food and color additives.

Lin CS, Shoaf SE, Griffiths JC.

Regul Toxicol Pharmacol. 1992 Feb;15(1):62-72. Review.

PMID:
1553413
35.

Induction of high-titer neutralizing antibodies, using hybrid human immunodeficiency virus V3-Ty viruslike particles in a clinically relevant adjuvant.

Griffiths JC, Berrie EL, Holdsworth LN, Moore JP, Harris SJ, Senior JM, Kingsman SM, Kingsman AJ, Adams SE.

J Virol. 1991 Jan;65(1):450-6.

36.

Inhibition of taurocholate efflux from rat hepatic canalicular membrane vesicles by glutathione disulfide.

Griffiths JC, Sies H, Meier PJ, Akerboom TP.

FEBS Lett. 1987 Mar 9;213(1):34-8.

37.

The metabolism of benzene and phenol by a reconstituted purified phenobarbital-induced rat liver mixed function oxidase system.

Griffiths JC, Kalf GF, Snyder R.

Adv Exp Med Biol. 1986;197:213-22. No abstract available.

PMID:
3094336
38.

Applications and limitations of peripheral blood lymphocyte immunoglobulin light chain analysis in the evaluation of non-Hodgkin's lymphoma.

Sobol RE, Dillman RO, Collins H, Griffiths JC, Green MR, Royston I.

Cancer. 1985 Oct 15;56(8):2005-10.

PMID:
3928135
39.

The long term results of single stem silastic arthroplasty of the great toe.

Brewood AF, Griffiths JC.

J R Coll Surg Edinb. 1985 Jun;30(3):159-61. No abstract available.

PMID:
4045772
40.

Relevance of the pharmacology of oral tegafur to its use as a 5-FU pro-drug.

Byfield JE, Hornbeck CL, Frankel SS, Sharp TR, Griffiths JC.

Cancer Treat Rep. 1985 Jun;69(6):645-52.

PMID:
3926308
41.

Phase I and pharmacologic study of oral ftorafur and X ray therapy in advanced gastrointestinal cancer.

Byfield JE, Sharp TR, Hornbeck CL, Frankel SS, Floyd RA, Griffiths JC.

Int J Radiat Oncol Biol Phys. 1985 Mar;11(3):597-602.

PMID:
3918971
42.

Bone marrow pressure changes under an inflatable tourniquet.

Griffiths JC, Sankarankutty M.

Hand. 1983 Feb;15(1):3-8.

PMID:
6852655
43.

Accidental injection of plastic into the hand.

Milling AF, Nath K, Griffiths JC.

J R Coll Surg Edinb. 1983 Jan;28(1):62-3. No abstract available.

PMID:
6834319
44.

The laboratory diagnosis of prostatic adenocarcinoma.

Griffiths JC.

Crit Rev Clin Lab Sci. 1983;19(3):187-204. Review.

PMID:
6144453
45.

Clearance of continuously infused 5-fluorouracil in adults having lung or gastrointestinal carcinoma with or without hepatic metastases.

Floyd RA, Hornbeck CL, Byfield JE, Griffiths JC, Frankel SS.

Drug Intell Clin Pharm. 1982 Sep;16(9):665-7.

PMID:
7128458
46.

Creatine kinase isoenzyme 1.

Griffiths JC.

Clin Lab Med. 1982 Sep;2(3):493-506. Review. No abstract available.

PMID:
6754222
47.

Use of immunoglobulin light chain analysis to detect bone marrow involvement in B-cell neoplasms.

Sobol RE, Astarita RW, Chisari FV, Griffiths JC, Royston I.

Clin Immunol Immunopathol. 1982 Jul;24(1):139-44. No abstract available.

PMID:
6809381
48.

Prostate specific acid phosphatase: further studies with immunological techniques.

Davies SN, Griffiths JC.

Clin Chim Acta. 1982 Jun 16;122(1):29-38. No abstract available.

PMID:
6178538
49.

Cerebrospinal fluid versus serum concentrations of 5-FU, allopurinol, and oxypurinol during treatment of metastatic brain cancer with 5-FU infusion, allopurinol, and radiation.

Hornbeck CL, Floyd RA, Byfield JE, Griffiths JC, Frankel S, Sharp TR.

Cancer Treat Rep. 1982 Mar;66(3):571-3. No abstract available.

PMID:
7060045
50.

gamma-Glutamyltransferase values in nonalcoholic drinking men.

Schuckit MA, Griffiths JC.

Am J Psychiatry. 1982 Feb;139(2):227-8. No abstract available.

PMID:
6119913

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