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Items: 1 to 50 of 154

1.

The mammalian decidual cell evolved from a cellular stress response.

Erkenbrack EM, Maziarz JD, Griffith OW, Liang C, Chavan AR, Nnamani MC, Wagner GP.

PLoS Biol. 2018 Aug 24;16(8):e2005594. doi: 10.1371/journal.pbio.2005594. eCollection 2018 Aug.

2.

Are there general laws for digit evolution in squamates? The loss and re-evolution of digits in a clade of fossorial lizards (Brachymeles, Scincinae).

Wagner GP, Griffith OW, Bergmann PJ, Bello-Hellegouarch G, Kohlsdorf T, Bhullar A, Siler CD.

J Morphol. 2018 Aug;279(8):1104-1119. doi: 10.1002/jmor.20834. Epub 2018 Jun 8.

PMID:
29884998
3.

Mechanisms of reproductive allocation as drivers of developmental plasticity in reptiles.

Van Dyke JU, Griffith OW.

J Exp Zool A Ecol Integr Physiol. 2018 Jul;329(6-7):275-286. doi: 10.1002/jez.2165. Epub 2018 May 7. Review.

PMID:
29733527
4.

Reply to Liu: Inflammation before implantation both in evolution and development.

Griffith OW, Chavan AR, Protopapas S, Maziarz J, Romero R, Wagner GP.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E3-E4. doi: 10.1073/pnas.1717001115. Epub 2017 Dec 12. No abstract available.

5.

The inflammation paradox in the evolution of mammalian pregnancy: turning a foe into a friend.

Chavan AR, Griffith OW, Wagner GP.

Curr Opin Genet Dev. 2017 Dec;47:24-32. doi: 10.1016/j.gde.2017.08.004. Epub 2017 Aug 29. Review.

PMID:
28850905
6.

The placenta as a model for understanding the origin and evolution of vertebrate organs.

Griffith OW, Wagner GP.

Nat Ecol Evol. 2017 Mar 23;1(4):72. doi: 10.1038/s41559-017-0072. Review.

PMID:
28812655
7.

Embryo implantation evolved from an ancestral inflammatory attachment reaction.

Griffith OW, Chavan AR, Protopapas S, Maziarz J, Romero R, Wagner GP.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6566-E6575. doi: 10.1073/pnas.1701129114. Epub 2017 Jul 26.

9.

Comparative genomics of hormonal signaling in the chorioallantoic membrane of oviparous and viviparous amniotes.

Griffith OW, Brandley MC, Whittington CM, Belov K, Thompson MB.

Gen Comp Endocrinol. 2017 Apr 1;244:19-29. doi: 10.1016/j.ygcen.2016.04.017. Epub 2016 Apr 19.

PMID:
27102939
10.

Allelic expression of mammalian imprinted genes in a matrotrophic lizard, Pseudemoia entrecasteauxii.

Griffith OW, Brandley MC, Belov K, Thompson MB.

Dev Genes Evol. 2016 Mar;226(2):79-85. doi: 10.1007/s00427-016-0531-x. Epub 2016 Mar 4.

PMID:
26943808
11.

Seahorse Brood Pouch Transcriptome Reveals Common Genes Associated with Vertebrate Pregnancy.

Whittington CM, Griffith OW, Qi W, Thompson MB, Wilson AB.

Mol Biol Evol. 2015 Dec;32(12):3114-31. doi: 10.1093/molbev/msv177. Epub 2015 Sep 1.

12.

Ancestral state reconstructions require biological evidence to test evolutionary hypotheses: A case study examining the evolution of reproductive mode in squamate reptiles.

Griffith OW, Blackburn DG, Brandley MC, Van Dyke JU, Whittington CM, Thompson MB.

J Exp Zool B Mol Dev Evol. 2015 Sep;324(6):493-503. doi: 10.1002/jez.b.22614. Epub 2015 Mar 2. Review.

PMID:
25732809
13.

High food abundance permits the evolution of placentotrophy: evidence from a placental lizard, Pseudemoia entrecasteauxii.

Van Dyke JU, Griffith OW, Thompson MB.

Am Nat. 2014 Aug;184(2):198-210. doi: 10.1086/677138. Epub 2014 Jul 8.

PMID:
25058280
14.

Placental lipoprotein lipase (LPL) gene expression in a placentotrophic lizard, Pseudemoia entrecasteauxii.

Griffith OW, Ujvari B, Belov K, Thompson MB.

J Exp Zool B Mol Dev Evol. 2013 Nov;320(7):465-70. doi: 10.1002/jez.b.22526. Epub 2013 Aug 12.

PMID:
23939756
15.

No implantation in an extra-uterine pregnancy of a placentotrophic reptile.

Griffith OW, Van Dyke JU, Thompson MB.

Placenta. 2013 Jun;34(6):510-1. doi: 10.1016/j.placenta.2013.03.002. Epub 2013 Mar 20.

PMID:
23522396
16.

Crystallization and preliminary crystallographic analysis of bifunctional gamma-glutamylcysteine synthetase-glutatione synthetase from Streptococcus agalactiae.

Nakashima Y, Nii H, Janowiak BE, Griffith OW, Hibi T.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 1;65(Pt 7):678-80. doi: 10.1107/S1744309109018636. Epub 2009 Jun 27.

17.

Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction.

Nicholls SJ, Wang Z, Koeth R, Levison B, DelFraino B, Dzavik V, Griffith OW, Hathaway D, Panza JA, Nissen SE, Hochman JS, Hazen SL.

Circulation. 2007 Nov 13;116(20):2315-24. Epub 2007 Oct 29.

PMID:
17967979
18.

Gamma-glutamylcysteine synthetase-glutathione synthetase: domain structure and identification of residues important in substrate and glutathione binding.

Janowiak BE, Hayward MA, Peterson FC, Volkman BF, Griffith OW.

Biochemistry. 2006 Sep 5;45(35):10461-73.

PMID:
16939198
19.

Post-translational modification of manganese superoxide dismutase in acutely rejecting cardiac transplants: role of inducible nitric oxide synthase.

Nilakantan V, Halligan NL, Nguyen TK, Hilton G, Khanna AK, Roza AM, Johnson CP, Adams MB, Griffith OW, Pieper GM.

J Heart Lung Transplant. 2005 Oct;24(10):1591-9.

PMID:
16210135
20.
21.

Variable efficacy of N6-(1-iminoethyl)-L-lysine in acute cardiac transplant rejection.

Pieper GM, Nilakantan V, Hilton G, Zhou X, Khanna AK, Halligan NL, Felix CC, Kampalath B, Griffith OW, Hayward MA, Roza AM, Adams MB.

Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H525-34.

22.

Structural characterization and kinetics of nitric-oxide synthase inhibition by novel N5-(iminoalkyl)- and N5-(iminoalkenyl)-ornithines.

Bretscher LE, Li H, Poulos TL, Griffith OW.

J Biol Chem. 2003 Nov 21;278(47):46789-97. Epub 2003 Sep 5.

23.

Non-heme iron protein: a potential target of nitric oxide in acute cardiac allograft rejection.

Pieper GM, Halligan NL, Hilton G, Konorev EA, Felix CC, Roza AM, Adams MB, Griffith OW.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3125-30. Epub 2003 Mar 6.

24.

Glutaminase and the control of airway pH: yet another problem for the asthmatic lung?

Griffith OW.

Am J Respir Crit Care Med. 2002 Jan 1;165(1):1-2. Review. No abstract available.

PMID:
11779720
25.

Escherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding.

Kelly BS, Antholine WE, Griffith OW.

J Biol Chem. 2002 Jan 4;277(1):50-8. Epub 2001 Oct 23.

26.

In vivo proton (H1) magnetic resonance spectroscopy for cervical carcinoma.

Allen JR, Prost RW, Griffith OW, Erickson SJ, Erickson BA.

Am J Clin Oncol. 2001 Oct;24(5):522-9.

PMID:
11586108
27.

Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.

Raman CS, Li H, Martásek P, Babu BR, Griffith OW, Masters BS, Poulos TL.

J Biol Chem. 2001 Jul 13;276(28):26486-91. Epub 2001 Apr 30.

28.

Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3.

Shi Y, Pritchard KA Jr, Holman P, Rafiee P, Griffith OW, Kalyanaraman B, Baker JE.

Free Radic Biol Med. 2000 Oct 15;29(8):695-703.

PMID:
11053770
29.

Strategies to reduce side effects of interleukin-2: evaluation of the antihypotensive agent NG-monomethyl-L-arginine.

Kilbourn RG, Fonseca GA, Trissel LA, Griffith OW.

Cancer J Sci Am. 2000 Feb;6 Suppl 1:S21-30.

PMID:
10685654
30.

Biologic and pharmacologic regulation of mammalian glutathione synthesis.

Griffith OW.

Free Radic Biol Med. 1999 Nov;27(9-10):922-35. Review.

PMID:
10569625
31.
32.

Adaptation to chronic hypoxia confers tolerance to subsequent myocardial ischemia by increased nitric oxide production.

Baker JE, Holman P, Kalyanaraman B, Griffith OW, Pritchard KA Jr.

Ann N Y Acad Sci. 1999 Jun 30;874:236-53.

PMID:
10415535
33.

The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase.

Griffith OW, Mulcahy RT.

Adv Enzymol Relat Areas Mol Biol. 1999;73:209-67, xii. Review.

PMID:
10218110
34.

Design of isoform-selective inhibitors of nitric oxide synthase.

Babu BR, Griffith OW.

Curr Opin Chem Biol. 1998 Aug;2(4):491-500. Review.

PMID:
9736922
35.

Expression and purification of human gamma-glutamylcysteine synthetase.

Misra I, Griffith OW.

Protein Expr Purif. 1998 Jul;13(2):268-76.

PMID:
9675072
36.
37.
38.
39.

Inhibition of endothelial cell amino acid transport System y+ by arginine analogs that inhibit nitric oxide synthase.

McDonald KK, Rouhani R, Handlogten ME, Block ER, Griffith OW, Allison RD, Kilberg MS.

Biochim Biophys Acta. 1997 Feb 21;1324(1):133-41.

40.
41.

Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft.

Hare CB, Elion GB, Colvin OM, Ali-Osman F, Griffith OW, Petros WP, Keir S, Marcelli SL, Bigner DD, Friedman HS.

Cancer Chemother Pharmacol. 1997;40(5):409-14.

PMID:
9272117
42.

L-amino acid oxidase (LOX) modulation of melphalan activity against intracranial glioma.

Moynihan K, Elion GB, Pegram C, Reist CJ, Wellner D, Bigner DD, Griffith OW, Friedman HS.

Cancer Chemother Pharmacol. 1997;39(3):179-86.

PMID:
8996517
43.

NO in septic shock: good, bad or ugly? Learning from iNOS knockouts.

Gross SS, Kilbourn RG, Griffith OW.

Trends Microbiol. 1996 Feb;4(2):47-9. No abstract available.

PMID:
8820564
44.

Nitric oxide synthase inhibitors: amino acids.

Griffith OW, Kilbourn RG.

Methods Enzymol. 1996;268:375-92. No abstract available.

PMID:
8782604
45.
46.

Pulmonary oxygen toxicity in mice is characterized by alterations in ascorbate redox status.

Rusakow LS, Han J, Hayward MA, Griffith OW.

J Appl Physiol (1985). 1995 Nov;79(5):1769-76.

PMID:
8594040
47.

NG-methyl-L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension.

Kilbourn RG, Fonseca GA, Griffith OW, Ewer M, Price K, Striegel A, Jones E, Logothetis CJ.

Crit Care Med. 1995 Jun;23(6):1018-24.

PMID:
7774211
48.
49.

S-alkyl-L-thiocitrullines. Potent stereoselective inhibitors of nitric oxide synthase with strong pressor activity in vivo.

Narayanan K, Spack L, McMillan K, Kilbourn RG, Hayward MA, Masters BS, Griffith OW.

J Biol Chem. 1995 May 12;270(19):11103-10.

50.

The effect of L-amino acid oxidase on activity of melphalan against an intracranial xenograft.

Rich JN, Elion GB, Wellner D, Colvin OM, Groothuis DR, Hilton JH, Schlageter KE, Bigner DD, Griffith OW, Friedman HS.

Cancer Chemother Pharmacol. 1995;36(5):379-84.

PMID:
7634379

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