Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 360


Development of encoded Broccoli RNA aptamers for live cell imaging of alphavirus genomic and subgenomic RNAs.

Nilaratanakul V, Hauer DA, Griffin DE.

Sci Rep. 2020 Mar 23;10(1):5233. doi: 10.1038/s41598-020-61573-3.


A durable protective immune response to wild-type measles virus infection of macaques is due to viral replication and spread in lymphoid tissues.

Lin WW, Moran E, Adams RJ, Sievers RE, Hauer D, Godin S, Griffin DE.

Sci Transl Med. 2020 Apr 1;12(537). pii: eaax7799. doi: 10.1126/scitranslmed.aax7799.


A Rewarding Career Unraveling the Pathogenesis of Viral Infections.

Griffin DE.

Annu Rev Virol. 2020 Mar 24. doi: 10.1146/annurev-virology-012420-024942. [Epub ahead of print]


Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice.

Abraham R, McPherson RL, Dasovich M, Badiee M, Leung AKL, Griffin DE.

mBio. 2020 Feb 11;11(1). pii: e03253-19. doi: 10.1128/mBio.03253-19.


Interferon-Gamma Modulation of the Local T Cell Response to Alphavirus Encephalomyelitis.

Baxter VK, Griffin DE.

Viruses. 2020 Jan 16;12(1). pii: E113. doi: 10.3390/v12010113.


Association of persistent wild-type measles virus RNA with long-term humoral immunity in rhesus macaques.

Nelson AN, Lin WW, Shivakoti R, Putnam NE, Mangus L, Adams RJ, Hauer D, Baxter VK, Griffin DE.

JCI Insight. 2020 Feb 13;5(3). pii: 134992. doi: 10.1172/jci.insight.134992.


Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens.

Mina MJ, Kula T, Leng Y, Li M, de Vries RD, Knip M, Siljander H, Rewers M, Choy DF, Wilson MS, Larman HB, Nelson AN, Griffin DE, de Swart RL, Elledge SJ.

Science. 2019 Nov 1;366(6465):599-606. doi: 10.1126/science.aay6485.


NF-κB Activation Promotes Alphavirus Replication in Mature Neurons.

Yeh JX, Park E, Schultz KLW, Griffin DE.

J Virol. 2019 Nov 26;93(24). pii: e01071-19. doi: 10.1128/JVI.01071-19. Print 2019 Dec 15.


Human Schwann cells are susceptible to infection with Zika and yellow fever viruses, but not dengue virus.

Dhiman G, Abraham R, Griffin DE.

Sci Rep. 2019 Jul 9;9(1):9951. doi: 10.1038/s41598-019-46389-0.


20th International Conference on Emerging Infectious Diseases in the Pacific Rim Organized by the United States-Japan Cooperative Medical Sciences Program (USJCMSP).

USJCMSP AIDS, ARI, Cancer, Hepatitis, Immunology and Viral Diseases Panels, Bernabe KG, Lu KT, Handley FG, Griffin DE, Kurane I, Iwamoto A, Gao GF, Krammer F.

Vaccines (Basel). 2019 Apr 2;7(2). pii: E35. doi: 10.3390/vaccines7020035.


2018 international meeting of the Global Virus Network.

Brechot C, Bryant J, Endtz H, Garry RF, Griffin DE, Lewin SR, Mercer N, Osterhaus A, Picot V, Vahlne A, Verjans GMGM, Weaver S.

Antiviral Res. 2019 Mar;163:140-148. doi: 10.1016/j.antiviral.2019.01.013. Epub 2019 Jan 25. Review.


Modeling the measles paradox reveals the importance of cellular immunity in regulating viral clearance.

Morris SE, Yates AJ, de Swart RL, de Vries RD, Mina MJ, Nelson AN, Lin WW, Kouyos RD, Griffin DE, Grenfell BT.

PLoS Pathog. 2018 Dec 28;14(12):e1007493. doi: 10.1371/journal.ppat.1007493. eCollection 2018 Dec.


Interferon regulatory factors 3 and 7 have distinct roles in the pathogenesis of alphavirus encephalomyelitis.

Schultz KLW, Troisi EM, Baxter VK, Glowinski R, Griffin DE.

J Gen Virol. 2019 Jan;100(1):46-62. doi: 10.1099/jgv.0.001174. Epub 2018 Nov 19.


ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication.

Abraham R, Hauer D, McPherson RL, Utt A, Kirby IT, Cohen MS, Merits A, Leung AKL, Griffin DE.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10457-E10466. doi: 10.1073/pnas.1812130115. Epub 2018 Oct 15.


Preparation of Recombinant Alphaviruses for Functional Studies of ADP-Ribosylation.

Abraham R, McPherson RL, Sreekumar E, Leung AKL, Griffin DE.

Methods Mol Biol. 2018;1813:297-316. doi: 10.1007/978-1-4939-8588-3_21. Erratum in: Methods Mol Biol. 2018;1813:E1.


[No title available]

Greenberg HB, Griffin DE.

Curr Opin Virol. 2018 Apr;29:v-vii. doi: 10.1016/j.coviro.2018.04.005. No abstract available.


Corrigendum: Death and gastrointestinal bleeding complicate encephalomyelitis in mice with delayed appearance of CNS IgM after intranasal alphavirus infection.

Baxter VK, Troisi EM, Pate NM, Zhao JN, Griffin DE.

J Gen Virol. 2018 May;99(5):759. doi: 10.1099/jgv.0.001062. No abstract available.


Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases.

Leung AKL, McPherson RL, Griffin DE.

PLoS Pathog. 2018 Mar 22;14(3):e1006864. doi: 10.1371/journal.ppat.1006864. eCollection 2018 Mar. No abstract available.


Understanding the causes and consequences of measles virus persistence.

Griffin DE, Lin WW, Nelson AN.

F1000Res. 2018 Feb 28;7:237. doi: 10.12688/f1000research.12094.1. eCollection 2018. Review.


Death and gastrointestinal bleeding complicate encephalomyelitis in mice with delayed appearance of CNS IgM after intranasal alphavirus infection.

Baxter VK, Troisi EM, Pate NM, Zhao JN, Griffin DE.

J Gen Virol. 2018 Mar;99(3):309-320. doi: 10.1099/jgv.0.001005. Erratum in: J Gen Virol. 2018 May;99(5):759.


Germ Line IgM Is Sufficient, but Not Required, for Antibody-Mediated Alphavirus Clearance from the Central Nervous System.

Nilaratanakul V, Chen J, Tran O, Baxter VK, Troisi EM, Yeh JX, Griffin DE.

J Virol. 2018 Mar 14;92(7). pii: e02081-17. doi: 10.1128/JVI.02081-17. Print 2018 Apr 1.


Interleukin-10 Modulation of Virus Clearance and Disease in Mice with Alphaviral Encephalomyelitis.

Martin NM, Griffin DE.

J Virol. 2018 Feb 26;92(6). pii: e01517-17. doi: 10.1128/JVI.01517-17. Print 2018 Mar 15.


Measles Vaccine.

Griffin DE.

Viral Immunol. 2018 Mar;31(2):86-95. doi: 10.1089/vim.2017.0143. Epub 2017 Dec 19. Review.


Evolution of T Cell Responses during Measles Virus Infection and RNA Clearance.

Nelson AN, Putnam N, Hauer D, Baxter VK, Adams RJ, Griffin DE.

Sci Rep. 2017 Sep 13;7(1):11474. doi: 10.1038/s41598-017-10965-z.


Why are neurons susceptible to Zika virus?

Griffin DE.

Science. 2017 Jul 7;357(6346):33-34. doi: 10.1126/science.aan8626. No abstract available.


Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network.

Aliota MT, Bassit L, Bradrick SS, Cox B, Garcia-Blanco MA, Gavegnano C, Friedrich TC, Golos TG, Griffin DE, Haddow AD, Kallas EG, Kitron U, Lecuit M, Magnani DM, Marrs C, Mercer N, McSweegan E, Ng LFP, O'Connor DH, Osorio JE, Ribeiro GS, Ricciardi M, Rossi SL, Saade G, Schinazi RF, Schott-Lerner GO, Shan C, Shi PY, Watkins DI, Vasilakis N, Weaver SC.

Antiviral Res. 2017 Aug;144:223-246. doi: 10.1016/j.antiviral.2017.06.001. Epub 2017 Jun 6. Review.


Development and characterization of Sindbis virus with encoded fluorescent RNA aptamer Spinach2 for imaging of replication and immune-mediated changes in intracellular viral RNA.

Nilaratanakul V, Hauer DA, Griffin DE.

J Gen Virol. 2017 May;98(5):992-1003. doi: 10.1099/jgv.0.000755. Epub 2017 May 30.


Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis.

Baxter VK, Glowinski R, Braxton AM, Potter MC, Slusher BS, Griffin DE.

Virology. 2017 Aug;508:134-149. doi: 10.1016/j.virol.2017.05.013. Epub 2017 May 19.


Within host RNA virus persistence: mechanisms and consequences.

Randall RE, Griffin DE.

Curr Opin Virol. 2017 Apr;23:35-42. doi: 10.1016/j.coviro.2017.03.001. Epub 2017 Mar 17. Review.


Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes.

Vermillion MS, Lei J, Shabi Y, Baxter VK, Crilly NP, McLane M, Griffin DE, Pekosz A, Klein SL, Burd I.

Nat Commun. 2017 Feb 21;8:14575. doi: 10.1038/ncomms14575.


ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence.

McPherson RL, Abraham R, Sreekumar E, Ong SE, Cheng SJ, Baxter VK, Kistemaker HA, Filippov DV, Griffin DE, Leung AK.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1666-1671. doi: 10.1073/pnas.1621485114. Epub 2017 Jan 31.


Plasma Cytokines and Chemokines in Zambian Children With Measles: Innate Responses and Association With HIV-1 Coinfection and In-Hospital Mortality.

Lin WW, Nelson AN, Ryon JJ, Moss WJ, Griffin DE.

J Infect Dis. 2017 Mar 1;215(5):830-839. doi: 10.1093/infdis/jix012.


Interferon gamma modulation of disease manifestation and the local antibody response to alphavirus encephalomyelitis.

Baxter VK, Griffin DE.

J Gen Virol. 2016 Nov;97(11):2908-2925. doi: 10.1099/jgv.0.000613. Epub 2016 Sep 22.


Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis.

Manivannan S, Baxter VK, Schultz KL, Slusher BS, Griffin DE.

J Virol. 2016 Sep 29;90(20):9251-62. doi: 10.1128/JVI.01045-16. Print 2016 Oct 15.


Impact of biochar amendment on soil water soluble carbon in the context of extreme hydrological events.

Wang D, Griffin DE, Parikh SJ, Scow KM.

Chemosphere. 2016 Oct;160:287-92. doi: 10.1016/j.chemosphere.2016.06.100. Epub 2016 Jul 6.


Dedication to Dr. Richard T. Johnson.

Nath A, Griffin DE.

Neurotherapeutics. 2016 Jul;13(3):451-2. doi: 10.1007/s13311-016-0456-0. No abstract available.


T cell-derived interleukin-10 is an important regulator of the Th17 response during lethal alphavirus encephalomyelitis.

Kulcsar KA, Griffin DE.

J Neuroimmunol. 2016 Jun 15;295-296:60-7. doi: 10.1016/j.jneuroim.2016.04.010. Epub 2016 Apr 13.


Alphavirus Encephalomyelitis: Mechanisms and Approaches to Prevention of Neuronal Damage.

Griffin DE.

Neurotherapeutics. 2016 Jul;13(3):455-60. doi: 10.1007/s13311-016-0434-6. Review.


Neurotropic virus infections as the cause of immediate and delayed neuropathology.

Ludlow M, Kortekaas J, Herden C, Hoffmann B, Tappe D, Trebst C, Griffin DE, Brindle HE, Solomon T, Brown AS, van Riel D, Wolthers KC, Pajkrt D, Wohlsein P, Martina BEE, Baumgärtner W, Verjans GM, Osterhaus ADME.

Acta Neuropathol. 2016 Feb;131(2):159-184. doi: 10.1007/s00401-015-1511-3. Epub 2015 Dec 10. Review.


Measles Virus Neutralizing Antibody Response, Cell-Mediated Immunity, and Immunoglobulin G Antibody Avidity Before and After Receipt of a Third Dose of Measles, Mumps, and Rubella Vaccine in Young Adults.

Fiebelkorn AP, Coleman LA, Belongia EA, Freeman SK, York D, Bi D, Kulkarni A, Audet S, Mercader S, McGrew M, Hickman CJ, Bellini WJ, Shivakoti R, Griffin DE, Beeler J.

J Infect Dis. 2016 Apr 1;213(7):1115-23. doi: 10.1093/infdis/jiv555. Epub 2015 Nov 23.


Distinct Immune Responses in Resistant and Susceptible Strains of Mice during Neurovirulent Alphavirus Encephalomyelitis.

Kulcsar KA, Baxter VK, Abraham R, Nelson A, Griffin DE.

J Virol. 2015 Aug;89(16):8280-91. doi: 10.1128/JVI.00173-15. Epub 2015 Jun 3.


Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.

Potter MC, Baxter VK, Mathey RW, Alt J, Rojas C, Griffin DE, Slusher BS.

J Neurovirol. 2015 Apr;21(2):159-73. doi: 10.1007/s13365-015-0314-6. Epub 2015 Feb 3.


Limited in vivo production of type I or type III interferon after infection of macaques with vaccine or wild-type strains of measles virus.

Shivakoti R, Hauer D, Adams RJ, Lin WH, Duprex WP, de Swart RL, Griffin DE.

J Interferon Cytokine Res. 2015 Apr;35(4):292-301. doi: 10.1089/jir.2014.0122. Epub 2014 Dec 17.


Interleukin 10 modulation of pathogenic Th17 cells during fatal alphavirus encephalomyelitis.

Kulcsar KA, Baxter VK, Greene IP, Griffin DE.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16053-8. doi: 10.1073/pnas.1418966111. Epub 2014 Oct 31.


Differentiation of neurons restricts Arbovirus replication and increases expression of the alpha isoform of IRF-7.

Schultz KL, Vernon PS, Griffin DE.

J Virol. 2015 Jan;89(1):48-60. doi: 10.1128/JVI.02394-14. Epub 2014 Oct 15.


Measles virus and the nervous system.

Griffin DE.

Handb Clin Neurol. 2014;123:577-90. doi: 10.1016/B978-0-444-53488-0.00027-4. No abstract available.


Current progress in pulmonary delivery of measles vaccine.

Griffin DE.

Expert Rev Vaccines. 2014 Jun;13(6):751-9. doi: 10.1586/14760584.2014.915753. Review.


Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.

Bogerd HP, Skalsky RL, Kennedy EM, Furuse Y, Whisnant AW, Flores O, Schultz KL, Putnam N, Barrows NJ, Sherry B, Scholle F, Garcia-Blanco MA, Griffin DE, Cullen BR.

J Virol. 2014 Jul;88(14):8065-76. doi: 10.1128/JVI.00985-14. Epub 2014 May 7.

Supplemental Content

Loading ...
Support Center