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Items: 1 to 50 of 346

1.

ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication.

Abraham R, Hauer D, McPherson RL, Utt A, Kirby IT, Cohen MS, Merits A, Leung AKL, Griffin DE.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10457-E10466. doi: 10.1073/pnas.1812130115. Epub 2018 Oct 15.

PMID:
30322911
2.

Preparation of Recombinant Alphaviruses for Functional Studies of ADP-Ribosylation.

Abraham R, McPherson RL, Sreekumar E, Leung AKL, Griffin DE.

Methods Mol Biol. 2018;1813:297-316. doi: 10.1007/978-1-4939-8588-3_21.

PMID:
30097877
3.

[No title available]

Greenberg HB, Griffin DE.

Curr Opin Virol. 2018 Apr;29:v-vii. doi: 10.1016/j.coviro.2018.04.005. No abstract available.

PMID:
29735182
4.

Corrigendum: Death and gastrointestinal bleeding complicate encephalomyelitis in mice with delayed appearance of CNS IgM after intranasal alphavirus infection.

Baxter VK, Troisi EM, Pate NM, Zhao JN, Griffin DE.

J Gen Virol. 2018 May;99(5):759. doi: 10.1099/jgv.0.001062. No abstract available.

PMID:
29717692
5.

Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases.

Leung AKL, McPherson RL, Griffin DE.

PLoS Pathog. 2018 Mar 22;14(3):e1006864. doi: 10.1371/journal.ppat.1006864. eCollection 2018 Mar. No abstract available.

6.

Understanding the causes and consequences of measles virus persistence.

Griffin DE, Lin WW, Nelson AN.

F1000Res. 2018 Feb 28;7:237. doi: 10.12688/f1000research.12094.1. eCollection 2018. Review.

7.

Death and gastrointestinal bleeding complicate encephalomyelitis in mice with delayed appearance of CNS IgM after intranasal alphavirus infection.

Baxter VK, Troisi EM, Pate NM, Zhao JN, Griffin DE.

J Gen Virol. 2018 Feb 1. doi: 10.1099/jgv.0.001005. [Epub ahead of print]

PMID:
29458665
8.

Germ Line IgM Is Sufficient, but Not Required, for Antibody-Mediated Alphavirus Clearance from the Central Nervous System.

Nilaratanakul V, Chen J, Tran O, Baxter VK, Troisi EM, Yeh JX, Griffin DE.

J Virol. 2018 Mar 14;92(7). pii: e02081-17. doi: 10.1128/JVI.02081-17. Print 2018 Apr 1.

9.

Interleukin-10 Modulation of Virus Clearance and Disease in Mice with Alphaviral Encephalomyelitis.

Martin NM, Griffin DE.

J Virol. 2018 Feb 26;92(6). pii: e01517-17. doi: 10.1128/JVI.01517-17. Print 2018 Mar 15.

10.

Measles Vaccine.

Griffin DE.

Viral Immunol. 2018 Mar;31(2):86-95. doi: 10.1089/vim.2017.0143. Epub 2017 Dec 19. Review.

PMID:
29256824
11.

Evolution of T Cell Responses during Measles Virus Infection and RNA Clearance.

Nelson AN, Putnam N, Hauer D, Baxter VK, Adams RJ, Griffin DE.

Sci Rep. 2017 Sep 13;7(1):11474. doi: 10.1038/s41598-017-10965-z.

12.

Why are neurons susceptible to Zika virus?

Griffin DE.

Science. 2017 Jul 7;357(6346):33-34. doi: 10.1126/science.aan8626. No abstract available.

PMID:
28684491
13.

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network.

Aliota MT, Bassit L, Bradrick SS, Cox B, Garcia-Blanco MA, Gavegnano C, Friedrich TC, Golos TG, Griffin DE, Haddow AD, Kallas EG, Kitron U, Lecuit M, Magnani DM, Marrs C, Mercer N, McSweegan E, Ng LFP, O'Connor DH, Osorio JE, Ribeiro GS, Ricciardi M, Rossi SL, Saade G, Schinazi RF, Schott-Lerner GO, Shan C, Shi PY, Watkins DI, Vasilakis N, Weaver SC.

Antiviral Res. 2017 Aug;144:223-246. doi: 10.1016/j.antiviral.2017.06.001. Epub 2017 Jun 6. Review.

14.

Development and characterization of Sindbis virus with encoded fluorescent RNA aptamer Spinach2 for imaging of replication and immune-mediated changes in intracellular viral RNA.

Nilaratanakul V, Hauer DA, Griffin DE.

J Gen Virol. 2017 May;98(5):992-1003. doi: 10.1099/jgv.0.000755. Epub 2017 May 30.

PMID:
28555544
15.

Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis.

Baxter VK, Glowinski R, Braxton AM, Potter MC, Slusher BS, Griffin DE.

Virology. 2017 Aug;508:134-149. doi: 10.1016/j.virol.2017.05.013. Epub 2017 May 19.

16.

Within host RNA virus persistence: mechanisms and consequences.

Randall RE, Griffin DE.

Curr Opin Virol. 2017 Apr;23:35-42. doi: 10.1016/j.coviro.2017.03.001. Epub 2017 Mar 17. Review.

17.

Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes.

Vermillion MS, Lei J, Shabi Y, Baxter VK, Crilly NP, McLane M, Griffin DE, Pekosz A, Klein SL, Burd I.

Nat Commun. 2017 Feb 21;8:14575. doi: 10.1038/ncomms14575.

18.

ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence.

McPherson RL, Abraham R, Sreekumar E, Ong SE, Cheng SJ, Baxter VK, Kistemaker HA, Filippov DV, Griffin DE, Leung AK.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1666-1671. doi: 10.1073/pnas.1621485114. Epub 2017 Jan 31.

19.

Plasma Cytokines and Chemokines in Zambian Children With Measles: Innate Responses and Association With HIV-1 Coinfection and In-Hospital Mortality.

Lin WW, Nelson AN, Ryon JJ, Moss WJ, Griffin DE.

J Infect Dis. 2017 Mar 1;215(5):830-839. doi: 10.1093/infdis/jix012.

20.
21.

Interferon gamma modulation of disease manifestation and the local antibody response to alphavirus encephalomyelitis.

Baxter VK, Griffin DE.

J Gen Virol. 2016 Nov;97(11):2908-2925. doi: 10.1099/jgv.0.000613. Epub 2016 Sep 22.

22.

Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis.

Manivannan S, Baxter VK, Schultz KL, Slusher BS, Griffin DE.

J Virol. 2016 Sep 29;90(20):9251-62. doi: 10.1128/JVI.01045-16. Print 2016 Oct 15.

23.

Impact of biochar amendment on soil water soluble carbon in the context of extreme hydrological events.

Wang D, Griffin DE, Parikh SJ, Scow KM.

Chemosphere. 2016 Oct;160:287-92. doi: 10.1016/j.chemosphere.2016.06.100. Epub 2016 Jul 6.

PMID:
27391051
24.

Dedication to Dr. Richard T. Johnson.

Nath A, Griffin DE.

Neurotherapeutics. 2016 Jul;13(3):451-2. doi: 10.1007/s13311-016-0456-0. No abstract available.

25.

T cell-derived interleukin-10 is an important regulator of the Th17 response during lethal alphavirus encephalomyelitis.

Kulcsar KA, Griffin DE.

J Neuroimmunol. 2016 Jun 15;295-296:60-7. doi: 10.1016/j.jneuroim.2016.04.010. Epub 2016 Apr 13.

26.

Alphavirus Encephalomyelitis: Mechanisms and Approaches to Prevention of Neuronal Damage.

Griffin DE.

Neurotherapeutics. 2016 Jul;13(3):455-60. doi: 10.1007/s13311-016-0434-6. Review.

27.

Neurotropic virus infections as the cause of immediate and delayed neuropathology.

Ludlow M, Kortekaas J, Herden C, Hoffmann B, Tappe D, Trebst C, Griffin DE, Brindle HE, Solomon T, Brown AS, van Riel D, Wolthers KC, Pajkrt D, Wohlsein P, Martina BEE, Baumgärtner W, Verjans GM, Osterhaus ADME.

Acta Neuropathol. 2016 Feb;131(2):159-184. doi: 10.1007/s00401-015-1511-3. Epub 2015 Dec 10. Review.

28.

Measles Virus Neutralizing Antibody Response, Cell-Mediated Immunity, and Immunoglobulin G Antibody Avidity Before and After Receipt of a Third Dose of Measles, Mumps, and Rubella Vaccine in Young Adults.

Fiebelkorn AP, Coleman LA, Belongia EA, Freeman SK, York D, Bi D, Kulkarni A, Audet S, Mercader S, McGrew M, Hickman CJ, Bellini WJ, Shivakoti R, Griffin DE, Beeler J.

J Infect Dis. 2016 Apr 1;213(7):1115-23. doi: 10.1093/infdis/jiv555. Epub 2015 Nov 23.

29.

Distinct Immune Responses in Resistant and Susceptible Strains of Mice during Neurovirulent Alphavirus Encephalomyelitis.

Kulcsar KA, Baxter VK, Abraham R, Nelson A, Griffin DE.

J Virol. 2015 Aug;89(16):8280-91. doi: 10.1128/JVI.00173-15. Epub 2015 Jun 3.

30.

Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.

Potter MC, Baxter VK, Mathey RW, Alt J, Rojas C, Griffin DE, Slusher BS.

J Neurovirol. 2015 Apr;21(2):159-73. doi: 10.1007/s13365-015-0314-6. Epub 2015 Feb 3.

31.

Limited in vivo production of type I or type III interferon after infection of macaques with vaccine or wild-type strains of measles virus.

Shivakoti R, Hauer D, Adams RJ, Lin WH, Duprex WP, de Swart RL, Griffin DE.

J Interferon Cytokine Res. 2015 Apr;35(4):292-301. doi: 10.1089/jir.2014.0122. Epub 2014 Dec 17.

32.

Interleukin 10 modulation of pathogenic Th17 cells during fatal alphavirus encephalomyelitis.

Kulcsar KA, Baxter VK, Greene IP, Griffin DE.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16053-8. doi: 10.1073/pnas.1418966111. Epub 2014 Oct 31.

33.

Differentiation of neurons restricts Arbovirus replication and increases expression of the alpha isoform of IRF-7.

Schultz KL, Vernon PS, Griffin DE.

J Virol. 2015 Jan;89(1):48-60. doi: 10.1128/JVI.02394-14. Epub 2014 Oct 15.

34.

Measles virus and the nervous system.

Griffin DE.

Handb Clin Neurol. 2014;123:577-90. doi: 10.1016/B978-0-444-53488-0.00027-4. No abstract available.

PMID:
25015505
35.

Current progress in pulmonary delivery of measles vaccine.

Griffin DE.

Expert Rev Vaccines. 2014 Jun;13(6):751-9. doi: 10.1586/14760584.2014.915753. Review.

PMID:
24837839
36.

Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.

Bogerd HP, Skalsky RL, Kennedy EM, Furuse Y, Whisnant AW, Flores O, Schultz KL, Putnam N, Barrows NJ, Sherry B, Scholle F, Garcia-Blanco MA, Griffin DE, Cullen BR.

J Virol. 2014 Jul;88(14):8065-76. doi: 10.1128/JVI.00985-14. Epub 2014 May 7.

37.

Vaccine-induced measles virus-specific T cells do not prevent infection or disease but facilitate subsequent clearance of viral RNA.

Lin WH, Pan CH, Adams RJ, Laube BL, Griffin DE.

MBio. 2014 Apr 15;5(2):e01047. doi: 10.1128/mBio.01047-14.

38.

Sprouty-2 regulates HIV-specific T cell polyfunctionality.

Chiu YL, Shan L, Huang H, Haupt C, Bessell C, Canaday DH, Zhang H, Ho YC, Powell JD, Oelke M, Margolick JB, Blankson JN, Griffin DE, Schneck JP.

J Clin Invest. 2014 Jan;124(1):198-208.

39.

Mice deficient in interferon-gamma or interferon-gamma receptor 1 have distinct inflammatory responses to acute viral encephalomyelitis.

Lee EY, Schultz KL, Griffin DE.

PLoS One. 2013 Oct 24;8(10):e76412. doi: 10.1371/journal.pone.0076412. eCollection 2013.

40.

Functional characterization of the alphavirus TF protein.

Snyder JE, Kulcsar KA, Schultz KL, Riley CP, Neary JT, Marr S, Jose J, Griffin DE, Kuhn RJ.

J Virol. 2013 Aug;87(15):8511-23. doi: 10.1128/JVI.00449-13. Epub 2013 May 29.

41.

Induction of dendritic cell production of type I and type III interferons by wild-type and vaccine strains of measles virus: role of defective interfering RNAs.

Shivakoti R, Siwek M, Hauer D, Schultz KL, Griffin DE.

J Virol. 2013 Jul;87(14):7816-27. doi: 10.1128/JVI.00261-13. Epub 2013 May 15.

42.

Vaxfectin adjuvant improves antibody responses of juvenile rhesus macaques to a DNA vaccine encoding the measles virus hemagglutinin and fusion proteins.

Lin WH, Vilalta A, Adams RJ, Rolland A, Sullivan SM, Griffin DE.

J Virol. 2013 Jun;87(12):6560-8. doi: 10.1128/JVI.00635-13. Epub 2013 Apr 3.

43.

Recruitment and retention of B cells in the central nervous system in response to alphavirus encephalomyelitis.

Metcalf TU, Baxter VK, Nilaratanakul V, Griffin DE.

J Virol. 2013 Mar;87(5):2420-9. doi: 10.1128/JVI.01769-12. Epub 2012 Dec 19.

44.

Poor immune responses of newborn rhesus macaques to measles virus DNA vaccines expressing the hemagglutinin and fusion glycoproteins.

Polack FP, Lydy SL, Lee SH, Rota PA, Bellini WJ, Adams RJ, Robinson HL, Griffin DE.

Clin Vaccine Immunol. 2013 Feb;20(2):205-10. doi: 10.1128/CVI.00394-12. Epub 2012 Dec 12.

45.

Immature CD4+CD8+ thymocytes are preferentially infected by measles virus in human thymic organ cultures.

Okamoto Y, Vricella LA, Moss WJ, Griffin DE.

PLoS One. 2012;7(9):e45999. doi: 10.1371/journal.pone.0045999. Epub 2012 Sep 24.

46.

Prolonged persistence of measles virus RNA is characteristic of primary infection dynamics.

Lin WH, Kouyos RD, Adams RJ, Grenfell BT, Griffin DE.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14989-94. doi: 10.1073/pnas.1211138109. Epub 2012 Aug 7.

47.

How respiratory viruses overcome mucosal defenses and exploit the unique environment of the respiratory tract.

von Messling VA, Griffin DE.

Curr Opin Virol. 2012 Jun;2(3):221-4. doi: 10.1016/j.coviro.2012.04.002. Epub 2012 May 1. No abstract available.

PMID:
22554837
48.

Measles virus, immune control, and persistence.

Griffin DE, Lin WH, Pan CH.

FEMS Microbiol Rev. 2012 May;36(3):649-62. doi: 10.1111/j.1574-6976.2012.00330.x. Epub 2012 Mar 13. Review.

49.

Clearance of virus infection from the CNS.

Griffin DE, Metcalf T.

Curr Opin Virol. 2011 Sep;1(3):216-21. doi: 10.1016/j.coviro.2011.05.021. Review.

50.

Alphavirus-induced encephalomyelitis: antibody-secreting cells and viral clearance from the nervous system.

Metcalf TU, Griffin DE.

J Virol. 2011 Nov;85(21):11490-501. doi: 10.1128/JVI.05379-11. Epub 2011 Aug 24.

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