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Items: 1 to 50 of 98

1.

A Novel Animal Model for Regional Microbial Dysbiosis of the Pioneer Microbial Community.

Malmuthuge N, Griebel PJ.

Front Microbiol. 2019 Jul 24;10:1706. doi: 10.3389/fmicb.2019.01706. eCollection 2019.

2.

Natural and inducible regulatory B cells are widely distributed in ovine lymphoid tissues.

Jimbo S, Griebel PJ, Lai K, Babiuk LA, Mutwiri G.

Vet Immunol Immunopathol. 2019 May;211:44-48. doi: 10.1016/j.vetimm.2019.04.005. Epub 2019 Apr 19.

PMID:
31084893
3.

Taxonomic and Functional Compositions of the Small Intestinal Microbiome in Neonatal Calves Provide a Framework for Understanding Early Life Gut Health.

Malmuthuge N, Liang G, Griebel PJ, Guan LL.

Appl Environ Microbiol. 2019 Mar 6;85(6). pii: e02534-18. doi: 10.1128/AEM.02534-18. Print 2019 Mar 15.

PMID:
30658973
4.

Fetal environment and fetal intestine are sterile during the third trimester of pregnancy.

Malmuthuge N, Griebel PJ.

Vet Immunol Immunopathol. 2018 Oct;204:59-64. doi: 10.1016/j.vetimm.2018.09.005. Epub 2018 Sep 26.

PMID:
30290960
5.

Lambda display phage as a mucosal vaccine delivery vehicle for peptide antigens.

González-Cano P, Gamage LNA, Marciniuk K, Hayes C, Napper S, Hayes S, Griebel PJ.

Vaccine. 2017 Dec 19;35(52):7256-7263. doi: 10.1016/j.vaccine.2017.11.010. Epub 2017 Nov 16.

PMID:
29153779
6.

CD335 (NKp46)+ T-Cell Recruitment to the Bovine Upper Respiratory Tract during a Primary Bovine Herpesvirus-1 Infection.

Osman RA, Griebel PJ.

Front Immunol. 2017 Oct 23;8:1393. doi: 10.3389/fimmu.2017.01393. eCollection 2017.

7.

Knowledge gaps that hamper prevention and control of Mycobacterium avium subspecies paratuberculosis infection.

Barkema HW, Orsel K, Nielsen SS, Koets AP, Rutten VPMG, Bannantine JP, Keefe GP, Kelton DF, Wells SJ, Whittington RJ, Mackintosh CG, Manning EJ, Weber MF, Heuer C, Forde TL, Ritter C, Roche S, Corbett CS, Wolf R, Griebel PJ, Kastelic JP, De Buck J.

Transbound Emerg Dis. 2018 May;65 Suppl 1:125-148. doi: 10.1111/tbed.12723. Epub 2017 Sep 22. Review.

PMID:
28941207
8.

Induction of interferon and interferon-induced antiviral effector genes following a primary bovine herpesvirus-1 (BHV-1) respiratory infection.

Osman R, Gonzalez-Cano P, Brownlie R, Griebel PJ.

J Gen Virol. 2017 Jul;98(7):1831-1842. doi: 10.1099/jgv.0.000825. Epub 2017 Jul 5.

PMID:
28675355
9.

Transcriptome analysis reveals regional and temporal differences in mucosal immune system development in the small intestine of neonatal calves.

Liang G, Malmuthuge N, Bao H, Stothard P, Griebel PJ, Guan le L.

BMC Genomics. 2016 Aug 11;17(1):602. doi: 10.1186/s12864-016-2957-y.

10.

Marked Differences in Mucosal Immune Responses Induced in Ileal versus Jejunal Peyer's Patches to Mycobacterium avium subsp. paratuberculosis Secreted Proteins following Targeted Enteric Infection in Young Calves.

Facciuolo A, Gonzalez-Cano P, Napper S, Griebel PJ, Mutharia LM.

PLoS One. 2016 Jul 7;11(7):e0158747. doi: 10.1371/journal.pone.0158747. eCollection 2016.

11.

Evidence for the existence of regulatory and effector B cell populations in Peyer's patches of sheep.

Jimbo S, Griebel PJ, Townsend H, Babiuk LA, Mutwiri G.

Vet Immunol Immunopathol. 2016 Jun;174:26-34. doi: 10.1016/j.vetimm.2016.04.006. Epub 2016 Apr 8.

PMID:
27185260
12.
13.

The Gut Microbiome and Its Potential Role in the Development and Function of Newborn Calf Gastrointestinal Tract.

Malmuthuge N, Griebel PJ, Guan le L.

Front Vet Sci. 2015 Sep 23;2:36. doi: 10.3389/fvets.2015.00036. eCollection 2015. Review.

14.

Tissue- and age-dependent expression of the bovine DEFB103 gene and protein.

Mirabzadeh-Ardakani A, Solie J, Gonzalez-Cano P, Schmutz SM, Griebel PJ.

Cell Tissue Res. 2016 Feb;363(2):479-90. doi: 10.1007/s00441-015-2258-9. Epub 2015 Aug 25.

PMID:
26299200
15.

BVDV vaccination in North America: risks versus benefits.

Griebel PJ.

Anim Health Res Rev. 2015 Jun;16(1):27-32. doi: 10.1017/S1466252315000080. Review.

PMID:
26050569
16.

Methanogen prevalence throughout the gastrointestinal tract of pre-weaned dairy calves.

Zhou M, Chen Y, Griebel PJ, Guan le L.

Gut Microbes. 2014;5(5):628-38. doi: 10.4161/19490976.2014.969649.

17.

IL-10 secreting CD21⁺ B cells are present in jejunal Peyer's patches of sheep during fetal development.

Jimbo S, Griebel PJ, Babiuk L, Mutwiri G.

Cell Tissue Res. 2014 May;356(2):417-25. doi: 10.1007/s00441-014-1803-2. Epub 2014 Apr 6.

PMID:
24705583
18.

Potential regulatory role of microRNAs in the development of bovine gastrointestinal tract during early life.

Liang G, Malmuthuge N, McFadden TB, Bao H, Griebel PJ, Stothard P, Guan le L.

PLoS One. 2014 Mar 28;9(3):e92592. doi: 10.1371/journal.pone.0092592. eCollection 2014.

19.

Safety, specificity and immunogenicity of a PrP(Sc)-specific prion vaccine based on the YYR disease specific epitope.

Taschuk R, Marciniuk K, Määttänen P, Madampage C, Hedlin P, Potter A, Lee J, Cashman NR, Griebel PJ, Napper S.

Prion. 2014 Jan-Feb;8(1):51-9.

PMID:
24509522
20.

Two functionally distinct myeloid dendritic cell subpopulations are present in bovine blood.

González-Cano P, Arsic N, Popowych YI, Griebel PJ.

Dev Comp Immunol. 2014 Jun;44(2):378-88. doi: 10.1016/j.dci.2014.01.014. Epub 2014 Feb 3.

PMID:
24502939
21.

Taxonomic identification of commensal bacteria associated with the mucosa and digesta throughout the gastrointestinal tracts of preweaned calves.

Malmuthuge N, Griebel PJ, Guan le L.

Appl Environ Microbiol. 2014 Mar;80(6):2021-8. doi: 10.1128/AEM.03864-13. Epub 2014 Jan 17.

22.

Peptide Arrays for Kinome Analysis of Livestock Species.

Daigle J, Van Wyk B, Trost B, Scruten E, Arsenault R, Kusalik A, Griebel PJ, Napper S.

Front Vet Sci. 2014 Oct 14;1:4. doi: 10.3389/fvets.2014.00004. eCollection 2014. Review.

23.

Host responses to persistent Mycobacterium avium subspecies paratuberculosis infection in surgically isolated bovine ileal segments.

Charavaryamath C, Gonzalez-Cano P, Fries P, Gomis S, Doig K, Scruten E, Potter A, Napper S, Griebel PJ.

Clin Vaccine Immunol. 2013 Feb;20(2):156-65. doi: 10.1128/CVI.00496-12. Epub 2012 Dec 5.

24.

Proinflammatory cytokine gene expression in endometrial cytobrush samples harvested from cows with and without subclinical endometritis.

Ghasemi F, Gonzalez-Cano P, Griebel PJ, Palmer C.

Theriogenology. 2012 Oct 15;78(7):1538-47. doi: 10.1016/j.theriogenology.2012.06.022. Epub 2012 Aug 25.

PMID:
22925636
25.

Induction of ligand-specific PrP (C) signaling in human neuronal cells.

Arsenault RJ, Li Y, Potter A, Griebel PJ, Kusalik A, Napper S.

Prion. 2012 Nov-Dec;6(5):477-88. doi: 10.4161/pri.21914. Epub 2012 Aug 23.

26.

Commensal microbiome effects on mucosal immune system development in the ruminant gastrointestinal tract.

Taschuk R, Griebel PJ.

Anim Health Res Rev. 2012 Jun;13(1):129-41. doi: 10.1017/S1466252312000096. Review.

PMID:
22853940
27.

Mycobacterium avium subsp. paratuberculosis inhibits gamma interferon-induced signaling in bovine monocytes: insights into the cellular mechanisms of Johne's disease.

Arsenault RJ, Li Y, Bell K, Doig K, Potter A, Griebel PJ, Kusalik A, Napper S.

Infect Immun. 2012 Sep;80(9):3039-48. doi: 10.1128/IAI.00406-12. Epub 2012 Jun 11.

28.

Mucosal immune response in newborn Holstein calves that had maternally derived antibodies and were vaccinated with an intranasal multivalent modified-live virus vaccine.

Hill KL, Hunsaker BD, Townsend HG, van Drunen Littel-van den Hurk S, Griebel PJ.

J Am Vet Med Assoc. 2012 May 15;240(10):1231-40. doi: 10.2460/javma.240.10.1231.

PMID:
22559114
29.

A systematic approach for analysis of peptide array kinome data.

Li Y, Arsenault RJ, Trost B, Slind J, Griebel PJ, Napper S, Kusalik A.

Sci Signal. 2012 Apr 17;5(220):pl2. doi: 10.1126/scisignal.2002429.

PMID:
22510468
30.

Stress significantly increases mortality following a secondary bacterial respiratory infection.

Hodgson PD, Aich P, Stookey J, Popowych Y, Potter A, Babiuk L, Griebel PJ.

Vet Res. 2012 Mar 21;43:21. doi: 10.1186/1297-9716-43-21.

31.

Regional and age dependent changes in gene expression of Toll-like receptors and key antimicrobial defence molecules throughout the gastrointestinal tract of dairy calves.

Malmuthuge N, Li M, Fries P, Griebel PJ, Guan LL.

Vet Immunol Immunopathol. 2012 Mar 15;146(1):18-26. doi: 10.1016/j.vetimm.2012.01.010. Epub 2012 Jan 20.

PMID:
22321738
32.

Interferon-gamma and B-cell Activating Factor (BAFF) promote bovine B cell activation independent of TLR9 and T-cell signaling.

Buchanan R, Popowych Y, Dagenais C, Arsic N, Mutwiri GK, Potter AA, Babiuk LA, Griebel PJ, Wilson HL.

Vet Immunol Immunopathol. 2012 Jan 15;145(1-2):453-63. doi: 10.1016/j.vetimm.2012.01.001. Epub 2012 Jan 10.

PMID:
22264737
33.

Distinct commensal bacteria associated with ingesta and mucosal epithelium in the gastrointestinal tracts of calves and chickens.

Malmuthuge N, Li M, Chen Y, Fries P, Griebel PJ, Baurhoo B, Zhao X, Guan LL.

FEMS Microbiol Ecol. 2012 Feb;79(2):337-47. doi: 10.1111/j.1574-6941.2011.01220.x. Epub 2011 Nov 1.

34.

Age-related changes in the distribution and frequency of myeloid and T cell populations in the small intestine of calves.

Fries PN, Popowych YI, Guan LL, Griebel PJ.

Cell Immunol. 2011;271(2):428-37. doi: 10.1016/j.cellimm.2011.08.012. Epub 2011 Aug 23.

PMID:
21917242
35.

Mucosal changes in a long-term bovine intestinal segment model following removal of ingesta and microflora.

Charavaryamath C, Fries P, Gomis S, Bell C, Doig K, Guan LL, Potter A, Napper S, Griebel PJ.

Gut Microbes. 2011 May-Jun;2(3):134-44. doi: 10.4161/gmic.2.3.16483.

PMID:
21869606
36.

B-cell activating factor (BAFF) promotes CpG ODN-induced B cell activation and proliferation.

Buchanan RM, Popowych Y, Arsic N, Townsend HG, Mutwiri GK, Potter AA, Babiuk LA, Griebel PJ, Wilson HL.

Cell Immunol. 2011;271(1):16-28. doi: 10.1016/j.cellimm.2011.05.016. Epub 2011 Jun 14.

PMID:
21724179
37.

Mucosal dendritic cell subpopulations in the small intestine of newborn calves.

Fries P, Popowych YI, Guan LL, Beskorwayne T, Potter A, Babiuk L, Griebel PJ.

Dev Comp Immunol. 2011 Oct;35(10):1040-51. doi: 10.1016/j.dci.2011.04.003. Epub 2011 Apr 20.

PMID:
21527286
38.

Mucosal dendritic cell diversity in the gastrointestinal tract.

Fries PN, Griebel PJ.

Cell Tissue Res. 2011 Jan;343(1):33-41. doi: 10.1007/s00441-010-1030-4. Epub 2010 Sep 8. Review.

PMID:
20824287
39.

TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides.

Booth JS, Arsenault R, Napper S, Griebel PJ, Potter AA, Babiuk LA, Mutwiri GK.

J Innate Immun. 2010;2(5):483-94. doi: 10.1159/000316574. Epub 2010 Jun 11.

40.

Stability, toxicity, and biological activity of host defense peptide BMAP28 and its inversed and retro-inversed isomers.

Kindrachuk J, Scruten E, Attah-Poku S, Bell K, Potter A, Babiuk LA, Griebel PJ, Napper S.

Biopolymers. 2011;96(1):14-24. doi: 10.1002/bip.21441.

PMID:
20336731
41.

Retro-inversion enhances the adjuvant and CpG co-adjuvant activity of host defence peptide Bac2A.

Scruten E, Kovacs-Nolan J, Griebel PJ, Latimer L, Kindrachuk J, Potter A, Babiuk LA, Littel-van den Hurk Sv, Napper S.

Vaccine. 2010 Apr 9;28(17):2945-56. doi: 10.1016/j.vaccine.2010.02.015. Epub 2010 Mar 1.

PMID:
20193790
42.

Kinome analysis of Toll-like receptor signaling in bovine monocytes.

Arsenault RJ, Jalal S, Babiuk LA, Potter A, Griebel PJ, Napper S.

J Recept Signal Transduct Res. 2009 Dec;29(6):299-311. doi: 10.3109/10799890903295127.

PMID:
19899953
43.

A novel regulatory B-cell population in sheep Peyer's patches spontaneously secretes IL-10 and downregulates TLR9-induced IFNalpha responses.

Booth JS, Griebel PJ, Babiuk LA, Mutwiri GK.

Mucosal Immunol. 2009 May;2(3):265-75. doi: 10.1038/mi.2009.6. Epub 2009 Mar 4.

PMID:
19262501
44.

Genome to kinome: species-specific peptide arrays for kinome analysis.

Jalal S, Arsenault R, Potter AA, Babiuk LA, Griebel PJ, Napper S.

Sci Signal. 2009 Jan 20;2(54):pl1. doi: 10.1126/scisignal.254pl1.

PMID:
19155530
45.

Amended recombinant cells (ARCs) expressing bovine IFN-gamma: an economical and highly effective adjuvant system.

Gaertner FH, Babiuk LA, Mutwiri G, Armstrong JM, Griebel PJ.

Vaccine. 2009 Feb 25;27(9):1377-85. doi: 10.1016/j.vaccine.2008.12.049. Epub 2009 Jan 16.

PMID:
19150640
46.
47.

Mucosal vaccination of the newborn: an unrealized opportunity.

Griebel PJ.

Expert Rev Vaccines. 2009 Jan;8(1):1-3. doi: 10.1586/14760584.8.1.1. Review. No abstract available.

PMID:
19093764
48.

Effect of stress on viral-bacterial synergy in bovine respiratory disease: novel mechanisms to regulate inflammation.

Hodgson PD, Aich P, Manuja A, Hokamp K, Roche FM, Brinkman FS, Potter A, Babiuk LA, Griebel PJ.

Comp Funct Genomics. 2005;6(4):244-50. doi: 10.1002/cfg.474.

49.

A sheep in wolf's clothes: can neutrophils direct the immune response?

Whale TA, Griebel PJ.

Vet J. 2009 May;180(2):169-77. doi: 10.1016/j.tvjl.2007.12.030. Epub 2008 Mar 4. Review.

PMID:
18296086
50.

Use of animal models in the development of human vaccines.

Gerdts V, Littel-van den Hurk Sv, Griebel PJ, Babiuk LA.

Future Microbiol. 2007 Dec;2(6):667-75. Review.

PMID:
18041907

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