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Items: 1 to 50 of 160


Identification of potential signature whistles from free-ranging common dolphins (Delphinus delphis) in South Africa.

Fearey J, Elwen SH, James BS, Gridley T.

Anim Cogn. 2019 Sep;22(5):777-789. doi: 10.1007/s10071-019-01274-1. Epub 2019 Jun 8.


Hybridization in bottlenose dolphins-A case study of Tursiops aduncus × T. truncatus hybrids and successful backcross hybridization events.

Gridley T, Elwen SH, Harris G, Moore DM, Hoelzel AR, Lampen F.

PLoS One. 2018 Sep 12;13(9):e0201722. doi: 10.1371/journal.pone.0201722. eCollection 2018.


Heaviside's dolphins (Cephalorhynchus heavisidii) relax acoustic crypsis to increase communication range.

Martin MJ, Gridley T, Elwen SH, Jensen FH.

Proc Biol Sci. 2018 Jul 18;285(1883). pii: 20181178. doi: 10.1098/rspb.2018.1178.


Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation.

Peterson SM, Turner JE, Harrington A, Davis-Knowlton J, Lindner V, Gridley T, Vary CPH, Liaw L.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1576-1593. doi: 10.1161/ATVBAHA.118.311092. Epub 2018 May 31.


Song recorded near a super-group of humpback whales on a mid-latitude feeding ground off South Africa.

Gridley T, Silva MFP, Wilkinson C, Seakamela SM, Elwen SH.

J Acoust Soc Am. 2018 Apr;143(4):EL298. doi: 10.1121/1.5032126.


Automatic classification of whistles from coastal dolphins of the southern African subregion.

Erbs F, Elwen SH, Gridley T.

J Acoust Soc Am. 2017 Apr;141(4):2489. doi: 10.1121/1.4978000.


Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates.

Basch ML, Brown RM 2nd, Jen HI, Semerci F, Depreux F, Edlund RK, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK.

Elife. 2016 Dec 14;5. pii: e19921. doi: 10.7554/eLife.19921.


Twenty Years in Maine: Integrating Insights from Developmental Biology into Translational Medicine in a Small State.

Gridley T.

Curr Top Dev Biol. 2016;116:435-43. doi: 10.1016/bs.ctdb.2015.10.004. Epub 2016 Jan 7. Review.


Notch signal reception is required in vascular smooth muscle cells for ductus arteriosus closure.

Krebs LT, Norton CR, Gridley T.

Genesis. 2016 Feb;54(2):86-90. doi: 10.1002/dvg.22916. Epub 2016 Jan 17.


Endoglin is required in Pax3-derived cells for embryonic blood vessel formation.

Young K, Krebs LT, Tweedie E, Conley B, Mancini M, Arthur HM, Liaw L, Gridley T, Vary C.

Dev Biol. 2016 Jan 1;409(1):95-105. doi: 10.1016/j.ydbio.2015.10.019. Epub 2015 Oct 19.


DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1.

Rostama B, Turner JE, Seavey GT, Norton CR, Gridley T, Vary CP, Liaw L.

Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2626-37. doi: 10.1161/ATVBAHA.115.306541. Epub 2015 Oct 15.


A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.

Castillo-Lluva S, Hontecillas-Prieto L, Blanco-Gómez A, Del Mar Sáez-Freire M, García-Cenador B, García-Criado J, Pérez-Andrés M, Orfao A, Cañamero M, Mao JH, Gridley T, Castellanos-Martín A, Pérez-Losada J.

Oncogene. 2015 Sep 3;34(36):4797-8. doi: 10.1038/onc.2015.322. No abstract available.


Measuring Satisfaction and Usability of FaceTime for Virtual Visits in Patients with Uncontrolled Diabetes.

Robinson MD, Branham AR, Locklear A, Robertson S, Gridley T.

Telemed J E Health. 2016 Feb;22(2):138-143. doi: 10.1089/tmj.2014.0238. Epub 2015 Aug 21.


Parent stem cells can serve as niches for their daughter cells.

Pardo-Saganta A, Tata PR, Law BM, Saez B, Chow RD, Prabhu M, Gridley T, Rajagopal J.

Nature. 2015 Jul 30;523(7562):597-601. doi: 10.1038/nature14553. Epub 2015 Jul 6.


A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.

Castillo-Lluva S, Hontecillas-Prieto L, Blanco-Gómez A, Del Mar Sáez-Freire M, García-Cenador B, García-Criado J, Pérez-Andrés M, Orfao A, Cañamero M, Mao JH, Gridley T, Castellanos-Martín A, Pérez-Losada J.

Oncogene. 2015 Sep 3;34(36):4777-90. doi: 10.1038/onc.2015.224. Epub 2015 Jun 22. Erratum in: Oncogene. 2015 Sep 3;34(36):4797-8.


Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors.

Villarejo A, Molina-Ortiz P, Montenegro Y, Moreno-Bueno G, Morales S, Santos V, Gridley T, Pérez-Moreno MA, Peinado H, Portillo F, Calés C, Cano A.

Carcinogenesis. 2015 May;36(5):585-97. doi: 10.1093/carcin/bgv021. Epub 2015 Mar 16.


Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.

Horvay K, Jardé T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE.

EMBO J. 2015 May 12;34(10):1319-35. doi: 10.15252/embj.201490881. Epub 2015 Mar 10.


Identification and characteristics of signature whistles in wild bottlenose dolphins (Tursiops truncatus) from Namibia.

Kriesell HJ, Elwen SH, Nastasi A, Gridley T.

PLoS One. 2014 Sep 9;9(9):e106317. doi: 10.1371/journal.pone.0106317. eCollection 2014.


The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life.

Zander MA, Cancino GI, Gridley T, Kaplan DR, Miller FD.

PLoS One. 2014 Aug 19;9(8):e104767. doi: 10.1371/journal.pone.0104767. eCollection 2014.


Lightening up a notch: Notch regulation of energy metabolism.

Gridley T, Kajimura S.

Nat Med. 2014 Aug;20(8):811-2. doi: 10.1038/nm.3650.


Overview of genetic tools and techniques to study Notch signaling in mice.

Gridley T, Groves AK.

Methods Mol Biol. 2014;1187:47-61. doi: 10.1007/978-1-4939-1139-4_4. Review.


Absence of a major role for the snai1 and snai3 genes in regulating skeletal muscle regeneration in mice.

Norton CR, Chen Y, Han XH, Bradley CK, Krebs LT, Yoon JK, Gridley T.

PLoS Curr. 2013 Nov 8;5. pii: doi: 10.1371/


The snail family gene snai3 is not essential for embryogenesis in mice.

Bradley CK, Norton CR, Chen Y, Han X, Booth CJ, Yoon JK, Krebs LT, Gridley T.

PLoS One. 2013 Jun 6;8(6):e65344. doi: 10.1371/journal.pone.0065344. Print 2013.


The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis.

Chen Y, Gridley T.

Biochem Biophys Res Commun. 2013 Jun 7;435(3):356-60. doi: 10.1016/j.bbrc.2013.04.086. Epub 2013 May 7.


Notch4 is required for tumor onset and perfusion.

Costa MJ, Wu X, Cuervo H, Srinivasan R, Bechis SK, Cheang E, Marjanovic O, Gridley T, Cvetic CA, Wang RA.

Vasc Cell. 2013 Apr 20;5(1):7. doi: 10.1186/2045-824X-5-7.


Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength.

Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T.

J Exp Med. 2013 Apr 8;210(4):683-97. doi: 10.1084/jem.20121798. Epub 2013 Mar 25.


Blockade of individual Notch ligands and receptors controls graft-versus-host disease.

Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I.

J Clin Invest. 2013 Apr;123(4):1590-604.


Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis.

Chen Y, Gridley T.

J Bone Miner Res. 2013 Jun;28(6):1412-21. doi: 10.1002/jbmr.1871.


Whistle vocalizations of Indo-Pacific bottlenose dolphins (Tursiops aduncus) inhabiting the south-west Indian Ocean.

Gridley T, Berggren P, Cockcroft VG, Janik VM.

J Acoust Soc Am. 2012 Dec;132(6):4032-40. doi: 10.1121/1.4763990.


Jagged1-mediated Notch signaling regulates mammalian inner ear development independent of lateral inhibition.

Hao J, Koesters R, Bouchard M, Gridley T, Pfannenstiel S, Plinkert PK, Zhang L, Praetorius M.

Acta Otolaryngol. 2012 Oct;132(10):1028-35.


Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells.

Batlle R, Alba-Castellón L, Loubat-Casanovas J, Armenteros E, Francí C, Stanisavljevic J, Banderas R, Martin-Caballero J, Bonilla F, Baulida J, Casal JI, Gridley T, García de Herreros A.

Oncogene. 2013 Jul 11;32(28):3381-9. doi: 10.1038/onc.2012.342. Epub 2012 Aug 6.


Notch Signaling during Oogenesis in Drosophila melanogaster.

Xu J, Gridley T.

Genet Res Int. 2012;2012:648207. doi: 10.1155/2012/648207. Epub 2012 May 3.


Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.

Xu K, Usary J, Kousis PC, Prat A, Wang DY, Adams JR, Wang W, Loch AJ, Deng T, Zhao W, Cardiff RD, Yoon K, Gaiano N, Ling V, Beyene J, Zacksenhaus E, Gridley T, Leong WL, Guidos CJ, Perou CM, Egan SE.

Cancer Cell. 2012 May 15;21(5):626-41. doi: 10.1016/j.ccr.2012.03.041.


Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

Helbig C, Gentek R, Backer RA, de Souza Y, Derks IA, Eldering E, Wagner K, Jankovic D, Gridley T, Moerland PD, Flavell RA, Amsen D.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9041-6. doi: 10.1073/pnas.1206044109. Epub 2012 May 21.


Molecular pathways of notch signaling in vascular smooth muscle cells.

Boucher J, Gridley T, Liaw L.

Front Physiol. 2012 Apr 9;3:81. doi: 10.3389/fphys.2012.00081. eCollection 2012.


Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins.

Zheng J, Watanabe H, Wines-Samuelson M, Zhao H, Gridley T, Kopan R, Shen J.

J Biol Chem. 2012 Jun 8;287(24):20356-68. doi: 10.1074/jbc.M112.349738. Epub 2012 Apr 13.


The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.

Krebs LT, Bradley CK, Norton CR, Xu J, Oram KF, Starling C, Deftos ML, Bevan MJ, Gridley T.

Genesis. 2012 Apr;50(4):366-74. doi: 10.1002/dvg.20813. Epub 2012 Jan 5.


Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development.

Tao G, Levay AK, Gridley T, Lincoln J.

Dev Biol. 2011 Nov 15;359(2):209-21. doi: 10.1016/j.ydbio.2011.08.022. Epub 2011 Sep 5.


Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.

Varnum-Finney B, Halasz LM, Sun M, Gridley T, Radtke F, Bernstein ID.

J Clin Invest. 2011 Mar;121(3):1207-16. doi: 10.1172/JCI43868.


Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.

Feng X, Krebs LT, Gridley T.

Development. 2010 Dec;137(24):4191-9. doi: 10.1242/dev.052043. Epub 2010 Nov 10.


Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.

Jeannet R, Mastio J, Macias-Garcia A, Oravecz A, Ashworth T, Geimer Le Lay AS, Jost B, Le Gras S, Ghysdael J, Gridley T, Honjo T, Radtke F, Aster JC, Chan S, Kastner P.

Blood. 2010 Dec 16;116(25):5443-54. doi: 10.1182/blood-2010-05-286658. Epub 2010 Sep 9.


Notch signaling in the vasculature.

Gridley T.

Curr Top Dev Biol. 2010;92:277-309. doi: 10.1016/S0070-2153(10)92009-7. Review.


BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation.

Mitsiadis TA, Graf D, Luder H, Gridley T, Bluteau G.

Development. 2010 Sep;137(18):3025-35. doi: 10.1242/dev.049528. Epub 2010 Aug 4.


Mesenchymal cell remodeling during mouse secondary palate reorientation.

Jin JZ, Tan M, Warner DR, Darling DS, Higashi Y, Gridley T, Ding J.

Dev Dyn. 2010 Jul;239(7):2110-7. doi: 10.1002/dvdy.22339.


Generation of mice with a conditional null allele of the Jagged2 gene.

Xu J, Krebs LT, Gridley T.

Genesis. 2010 Jun;48(6):390-3. doi: 10.1002/dvg.20626.


Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants.

Krebs LT, Starling C, Chervonsky AV, Gridley T.

Genesis. 2010 Mar;48(3):146-50. doi: 10.1002/dvg.20599.


Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE.

Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56. doi: 10.1152/ajplung.90550.2008. Epub 2009 Nov 6.


Smooth muscle Notch1 mediates neointimal formation after vascular injury.

Li Y, Takeshita K, Liu PY, Satoh M, Oyama N, Mukai Y, Chin MT, Krebs L, Kotlikoff MI, Radtke F, Gridley T, Liao JK.

Circulation. 2009 May 26;119(20):2686-92. doi: 10.1161/CIRCULATIONAHA.108.790485. Epub 2009 May 11.


Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.

Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V, Grilli A, López-Bigas N, Bellora N, Albà MM, Torres F, Duñach M, Sanjuan X, Gonzalez S, Gridley T, Capella G, Bigas A, Espinosa L.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6315-20. doi: 10.1073/pnas.0813221106. Epub 2009 Mar 26.

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