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Items: 1 to 50 of 266

1.

Alcohol's harms to others in Wales, United Kingdom: Nature, magnitude and associations with mental well-being.

Quigg Z, Bellis MA, Grey H, Webster J, Hughes K.

Addict Behav Rep. 2019 Feb 5;9:100162. doi: 10.1016/j.abrep.2019.100162. eCollection 2019 Jun.

2.

Associations between childhood deaths and adverse childhood experiences: An audit of data from a child death overview panel.

Grey HR, Ford K, Bellis MA, Lowey H, Wood S.

Child Abuse Negl. 2019 Apr;90:22-31. doi: 10.1016/j.chiabu.2019.01.020. Epub 2019 Feb 1.

3.

Proteasome-associated HECT-type ubiquitin ligase activity is required for plant immunity.

Furniss JJ, Grey H, Wang Z, Nomoto M, Jackson L, Tada Y, Spoel SH.

PLoS Pathog. 2018 Nov 20;14(11):e1007447. doi: 10.1371/journal.ppat.1007447. eCollection 2018 Nov.

4.

The development of hospital-based palliative care services in public hospitals in the Western Cape, South Africa.

Gwyther L, Krause R, Cupido C, Stanford J, Grey H, Credé T, De Vos A, Arendse J, Raubenheimer P.

S Afr Med J. 2018 Feb 1;108(2):86-89. doi: 10.7196/SAMJ.2017.v108i2.12524.

5.

A bend, flip and trap mechanism for transposon integration.

Morris ER, Grey H, McKenzie G, Jones AC, Richardson JM.

Elife. 2016 May 25;5. pii: e15537. doi: 10.7554/eLife.15537.

6.

Nuclear factor 90 uses an ADAR2-like binding mode to recognize specific bases in dsRNA.

Jayachandran U, Grey H, Cook AG.

Nucleic Acids Res. 2016 Feb 29;44(4):1924-36. doi: 10.1093/nar/gkv1508. Epub 2015 Dec 27.

7.

Structural Basis for the Inverted Repeat Preferences of mariner Transposases.

Trubitsyna M, Grey H, Houston DR, Finnegan DJ, Richardson JM.

J Biol Chem. 2015 May 22;290(21):13531-40. doi: 10.1074/jbc.M115.636704. Epub 2015 Apr 13.

8.

Structural role of the flanking DNA in mariner transposon excision.

Dornan J, Grey H, Richardson JM.

Nucleic Acids Res. 2015 Feb 27;43(4):2424-32. doi: 10.1093/nar/gkv096. Epub 2015 Feb 8.

9.

Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells.

Weiskopf D, Angelo MA, de Azeredo EL, Sidney J, Greenbaum JA, Fernando AN, Broadwater A, Kolla RV, De Silva AD, de Silva AM, Mattia KA, Doranz BJ, Grey HM, Shresta S, Peters B, Sette A.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):E2046-53. doi: 10.1073/pnas.1305227110. Epub 2013 Apr 11.

10.

Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.

Schulten V, Greenbaum JA, Hauser M, McKinney DM, Sidney J, Kolla R, Lindestam Arlehamn CS, Oseroff C, Alam R, Broide DH, Ferreira F, Grey HM, Sette A, Peters B.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3459-64. doi: 10.1073/pnas.1300512110. Epub 2013 Feb 11. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5269. Ferreira-Briza, Fatima [corrected to Ferreira, Fatima]. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8750.

11.

Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture.

Sidney J, Southwood S, Moore C, Oseroff C, Pinilla C, Grey HM, Sette A.

Curr Protoc Immunol. 2013 Feb;Chapter 18:Unit 18.3.. doi: 10.1002/0471142735.im1803s100.

12.

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.

Lindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A.

PLoS Pathog. 2013 Jan;9(1):e1003130. doi: 10.1371/journal.ppat.1003130. Epub 2013 Jan 24.

13.

T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.

Oseroff C, Sidney J, Vita R, Tripple V, McKinney DM, Southwood S, Brodie TM, Sallusto F, Grey H, Alam R, Broide D, Greenbaum JA, Kolla R, Peters B, Sette A.

J Immunol. 2012 Aug 15;189(4):1800-11. doi: 10.4049/jimmunol.1200850. Epub 2012 Jul 11.

14.

Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production.

Oseroff C, Sidney J, Tripple V, Grey H, Wood R, Broide DH, Greenbaum J, Kolla R, Peters B, Pomés A, Sette A.

J Immunol. 2012 Jul 15;189(2):679-88. doi: 10.4049/jimmunol.1200694. Epub 2012 Jun 15.

15.

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.

Ostrov DA, Grant BJ, Pompeu YA, Sidney J, Harndahl M, Southwood S, Oseroff C, Lu S, Jakoncic J, de Oliveira CA, Yang L, Mei H, Shi L, Shabanowitz J, English AM, Wriston A, Lucas A, Phillips E, Mallal S, Grey HM, Sette A, Hunt DF, Buus S, Peters B.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9959-64. doi: 10.1073/pnas.1207934109. Epub 2012 May 29.

16.

Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).

Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A.

J Immunol. 2012 May 15;188(10):5020-31. doi: 10.4049/jimmunol.1103556. Epub 2012 Apr 13.

17.

Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design.

Weiskopf D, Yauch LE, Angelo MA, John DV, Greenbaum JA, Sidney J, Kolla RV, De Silva AD, de Silva AM, Grey H, Peters B, Shresta S, Sette A.

J Immunol. 2011 Oct 15;187(8):4268-79. doi: 10.4049/jimmunol.1101970. Epub 2011 Sep 14.

18.

Molecular determinants of T cell epitope recognition to the common Timothy grass allergen.

Oseroff C, Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI, Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A.

J Immunol. 2010 Jul 15;185(2):943-55. doi: 10.4049/jimmunol.1000405. Epub 2010 Jun 16.

19.

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage.

Kotturi MF, Botten J, Maybeno M, Sidney J, Glenn J, Bui HH, Oseroff C, Crotty S, Peters B, Grey H, Altmann DM, Buchmeier MJ, Sette A.

Immunome Res. 2010 May 17;6:4. doi: 10.1186/1745-7580-6-4.

20.

Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available data.

Vaughan K, Greenbaum J, Kim Y, Vita R, Chung J, Peters B, Broide D, Goodman R, Grey H, Sette A.

J Allergy (Cairo). 2010;2010:628026. doi: 10.1155/2010/628026. Epub 2011 Feb 13.

21.

A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease.

Kotturi MF, Botten J, Sidney J, Bui HH, Giancola L, Maybeno M, Babin J, Oseroff C, Pasquetto V, Greenbaum JA, Peters B, Ting J, Do D, Vang L, Alexander J, Grey H, Buchmeier MJ, Sette A.

PLoS Pathog. 2009 Dec;5(12):e1000695. doi: 10.1371/journal.ppat.1000695. Epub 2009 Dec 18.

22.

Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens.

Sette A, Grey H, Oseroff C, Peters B, Moutaftsi M, Crotty S, Assarsson E, Greenbaum J, Kim Y, Kolla R, Tscharke D, Koelle D, Johnson RP, Blum J, Head S, Sidney J.

Vaccine. 2009 Dec 30;27 Suppl 6:G21-6. doi: 10.1016/j.vaccine.2009.10.011. Review.

23.

Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?

Kotturi MF, Assarsson E, Peters B, Grey H, Oseroff C, Pasquetto V, Sette A.

Immunome Res. 2009 Jun 17;5:3. doi: 10.1186/1745-7580-5-3.

24.

Correlates of protection efficacy induced by vaccinia virus-specific CD8+ T-cell epitopes in the murine intranasal challenge model.

Moutaftsi M, Salek-Ardakani S, Croft M, Peters B, Sidney J, Grey H, Sette A.

Eur J Immunol. 2009 Mar;39(3):717-22. doi: 10.1002/eji.200838815.

25.

Immunomic analysis of the repertoire of T-cell specificities for influenza A virus in humans.

Assarsson E, Bui HH, Sidney J, Zhang Q, Glenn J, Oseroff C, Mbawuike IN, Alexander J, Newman MJ, Grey H, Sette A.

J Virol. 2008 Dec;82(24):12241-51. doi: 10.1128/JVI.01563-08. Epub 2008 Oct 8.

26.

Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance.

Kotturi MF, Scott I, Wolfe T, Peters B, Sidney J, Cheroutre H, von Herrath MG, Buchmeier MJ, Grey H, Sette A.

J Immunol. 2008 Aug 1;181(3):2124-33.

27.

Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities.

Sette A, Moutaftsi M, Moyron-Quiroz J, McCausland MM, Davies DH, Johnston RJ, Peters B, Rafii-El-Idrissi Benhnia M, Hoffmann J, Su HP, Singh K, Garboczi DN, Head S, Grey H, Felgner PL, Crotty S.

Immunity. 2008 Jun;28(6):847-58. doi: 10.1016/j.immuni.2008.04.018.

28.

Dissociation between epitope hierarchy and immunoprevalence in CD8 responses to vaccinia virus western reserve.

Oseroff C, Peters B, Pasquetto V, Moutaftsi M, Sidney J, Panchanathan V, Tscharke DC, Maillere B, Grey H, Sette A.

J Immunol. 2008 Jun 1;180(11):7193-202.

29.

Measurement of MHC/peptide interactions by gel filtration.

Sidney J, Southwood S, Oseroff C, del Guercio MF, Sette A, Grey HM.

Curr Protoc Immunol. 2001 May;Chapter 18:Unit 18.3. doi: 10.1002/0471142735.im1803s31.

PMID:
18432745
30.

Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum.

Zarebski LM, Vaughan K, Sidney J, Peters B, Grey H, Janda KD, Casadevall A, Sette A.

Expert Rev Vaccines. 2008 Feb;7(1):55-74. doi: 10.1586/14760584.7.1.55. Review.

31.

Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes.

Assarsson E, Greenbaum JA, Sundström M, Schaffer L, Hammond JA, Pasquetto V, Oseroff C, Hendrickson RC, Lefkowitz EJ, Tscharke DC, Sidney J, Grey HM, Head SR, Peters B, Sette A.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2140-5. doi: 10.1073/pnas.0711573105. Epub 2008 Feb 1. Erratum in: Proc Natl Acad Sci U S A. 2008 May 6;105(18):6787.

32.

A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection.

Assarsson E, Sidney J, Oseroff C, Pasquetto V, Bui HH, Frahm N, Brander C, Peters B, Grey H, Sette A.

J Immunol. 2007 Jun 15;178(12):7890-901.

33.

Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses.

Moutaftsi M, Bui HH, Peters B, Sidney J, Salek-Ardakani S, Oseroff C, Pasquetto V, Crotty S, Croft M, Lefkowitz EJ, Grey H, Sette A.

J Immunol. 2007 Jun 1;178(11):6814-20.

34.

The CD8+ T-cell response to lymphocytic choriomeningitis virus involves the L antigen: uncovering new tricks for an old virus.

Kotturi MF, Peters B, Buendia-Laysa F Jr, Sidney J, Oseroff C, Botten J, Grey H, Buchmeier MJ, Sette A.

J Virol. 2007 May;81(10):4928-40. Epub 2007 Feb 28.

35.

Curation of complex, context-dependent immunological data.

Vita R, Vaughan K, Zarebski L, Salimi N, Fleri W, Grey H, Sathiamurthy M, Mokili J, Bui HH, Bourne PE, Ponomarenko J, de Castro R Jr, Chan RK, Sidney J, Wilson SS, Stewart S, Way S, Peters B, Sette A.

BMC Bioinformatics. 2006 Jul 12;7:341.

36.

A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus.

Moutaftsi M, Peters B, Pasquetto V, Tscharke DC, Sidney J, Bui HH, Grey H, Sette A.

Nat Biotechnol. 2006 Jul;24(7):817-9. Epub 2006 Jun 11.

PMID:
16767078
37.

HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products.

Pasquetto V, Bui HH, Giannino R, Banh C, Mirza F, Sidney J, Oseroff C, Tscharke DC, Irvine K, Bennink JR, Peters B, Southwood S, Cerundolo V, Grey H, Yewdell JW, Sette A.

J Immunol. 2005 Oct 15;175(8):5504-15. Erratum in: J Immunol. 2005 Dec 15;175(12):8440. Banh, Cindy [added].

38.

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation.

Oseroff C, Kos F, Bui HH, Peters B, Pasquetto V, Glenn J, Palmore T, Sidney J, Tscharke DC, Bennink JR, Southwood S, Grey HM, Yewdell JW, Sette A.

Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13980-5. Epub 2005 Sep 19.

39.

Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling.

Sugie K, Jeon MS, Grey HM.

Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14859-64. Epub 2004 Oct 1.

40.

Effector T cells have a lower ligand affinity threshold for activation than naive T cells.

Kimachi K, Sugie K, Grey HM.

Int Immunol. 2003 Jul;15(7):885-92.

PMID:
12807827
41.
44.

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.

Huang J, Lo PF, Zal T, Gascoigne NR, Smith BA, Levin SD, Grey HM.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9369-73. Epub 2002 Jun 20.

46.

How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.

Ostrov DA, Roden MM, Shi W, Palmieri E, Christianson GJ, Mendoza L, Villaflor G, Tilley D, Shastri N, Grey H, Almo SC, Roopenian D, Nathenson SG.

J Immunol. 2002 Jan 1;168(1):283-9.

47.

Epitope affinity for MHC class I determines helper requirement for CTL priming.

Franco A, Tilly DA, Gramaglia I, Croft M, Cipolla L, Meldal M, Grey HM.

Nat Immunol. 2000 Aug;1(2):145-50.

PMID:
11248807
48.

T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase.

Huang J, Tilly D, Altman A, Sugie K, Grey HM.

Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10923-9.

49.

Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma.

Ressing ME, van Driel WJ, Brandt RM, Kenter GG, de Jong JH, Bauknecht T, Fleuren GJ, Hoogerhout P, Offringa R, Sette A, Celis E, Grey H, Trimbos BJ, Kast WM, Melief CJ.

J Immunother. 2000 Mar-Apr;23(2):255-66.

PMID:
10746552
50.

TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway.

Huang J, Sugie K, La Face DM, Altman A, Grey HM.

Eur J Immunol. 2000 Jan;30(1):50-8.

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