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Items: 1 to 50 of 349

1.

YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells.

Wei T, Weiler SME, Tóth M, Sticht C, Lutz T, Thomann S, De La Torre C, Straub B, Merker S, Ruppert T, Marquardt J, Singer S, Gretz N, Schirmacher P, Breuhahn K.

Oncogene. 2019 Jul;38(27):5541-5550. doi: 10.1038/s41388-019-0801-y. Epub 2019 Apr 1.

PMID:
30936457
2.

MicroRNA-365a-3p inhibits c-Rel-mediated NF-κB signaling and the progression of pancreatic cancer.

Yin L, Xiao X, Georgikou C, Yin Y, Liu L, Karakhanova S, Luo Y, Gladkich J, Fellenberg J, Sticht C, Gretz N, Gross W, Herr I.

Cancer Lett. 2019 Jun 28;452:203-212. doi: 10.1016/j.canlet.2019.03.025. Epub 2019 Mar 23.

PMID:
30910589
3.

Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p.

Goeppert B, Truckenmueller F, Ori A, Fritz V, Albrecht T, Fraas A, Scherer D, Silos RG, Sticht C, Gretz N, Mehrabi A, Bewerunge-Hudler M, Pusch S, Bermejo JL, Dietrich P, Schirmacher P, Renner M, Roessler S.

Sci Rep. 2019 Mar 18;9(1):4796. doi: 10.1038/s41598-019-40857-3.

4.

A Novel Optical Tissue Clearing Protocol for Mouse Skeletal Muscle to Visualize Endplates in Their Tissue Context.

Williams MPI, Rigon M, Straka T, Hörner SJ, Thiel M, Gretz N, Hafner M, Reischl M, Rudolf R.

Front Cell Neurosci. 2019 Feb 27;13:49. doi: 10.3389/fncel.2019.00049. eCollection 2019.

5.

Upregulation of Tumor Susceptibility Gene 101 (TSG101) by mechanical stress in podocytes.

Sunohara M, Kriz W, Kränzlin B, Kretzler M, Gretz N, Endlich K, Endlich N.

Cell Mol Biol (Noisy-le-grand). 2019 Jan 31;65(1):84-88.

PMID:
30782301
6.

A cationic near infrared fluorescent agent and ethyl-cinnamate tissue clearing protocol for vascular staining and imaging.

Huang J, Brenna C, Khan AUM, Daniele C, Rudolf R, Heuveline V, Gretz N.

Sci Rep. 2019 Jan 24;9(1):521. doi: 10.1038/s41598-018-36741-1.

7.

SOX9 expression decreases survival of patients with intrahepatic cholangiocarcinoma by conferring chemoresistance.

Yuan X, Li J, Coulouarn C, Lin T, Sulpice L, Bergeat D, De La Torre C, Liebe R, Gretz N, Ebert MPA, Dooley S, Weng HL.

Br J Cancer. 2018 Nov;119(11):1358-1366. doi: 10.1038/s41416-018-0338-9. Epub 2018 Nov 13.

8.

Experimental ischaemic stroke induces transient cardiac atrophy and dysfunction.

Veltkamp R, Uhlmann S, Marinescu M, Sticht C, Finke D, Gretz N, Gröne HJ, Katus HA, Backs J, Lehmann LH.

J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):54-62. doi: 10.1002/jcsm.12335. Epub 2018 Oct 30.

9.

miRWalk: An online resource for prediction of microRNA binding sites.

Sticht C, De La Torre C, Parveen A, Gretz N.

PLoS One. 2018 Oct 18;13(10):e0206239. doi: 10.1371/journal.pone.0206239. eCollection 2018.

10.

Stem/Stromal Cells for Treatment of Kidney Injuries With Focus on Preclinical Models.

Torres Crigna A, Daniele C, Gamez C, Medina Balbuena S, Pastene DO, Nardozi D, Brenna C, Yard B, Gretz N, Bieback K.

Front Med (Lausanne). 2018 Jun 15;5:179. doi: 10.3389/fmed.2018.00179. eCollection 2018. Review.

11.
12.

Simvastatin inhibits sonic hedgehog signaling and stemness features of pancreatic cancer.

Yin Y, Liu L, Zhao Z, Yin L, Bauer N, Nwaeburu CC, Gladkich J, Gross W, Hackert T, Sticht C, Gretz N, Strobel O, Herr I.

Cancer Lett. 2018 Jul 10;426:14-24. doi: 10.1016/j.canlet.2018.04.001. Epub 2018 Apr 6.

PMID:
29627496
13.

Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart.

Jabs M, Rose AJ, Lehmann LH, Taylor J, Moll I, Sijmonsma TP, Herberich SE, Sauer SW, Poschet G, Federico G, Mogler C, Weis EM, Augustin HG, Yan M, Gretz N, Schmid RM, Adams RH, Gröne HJ, Hell R, Okun JG, Backs J, Nawroth PP, Herzig S, Fischer A.

Circulation. 2018 Jun 12;137(24):2592-2608. doi: 10.1161/CIRCULATIONAHA.117.029733. Epub 2018 Jan 20.

PMID:
29353241
14.

Epigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients.

González-Vallinas M, Rodríguez-Paredes M, Albrecht M, Sticht C, Stichel D, Gutekunst J, Pitea A, Sass S, Sánchez-Rivera FJ, Lorenzo-Bermejo J, Schmitt J, De La Torre C, Warth A, Theis FJ, Müller NS, Gretz N, Muley T, Meister M, Tschaharganeh DF, Schirmacher P, Matthäus F, Breuhahn K.

Mol Cancer Res. 2018 Mar;16(3):390-402. doi: 10.1158/1541-7786.MCR-17-0334. Epub 2018 Jan 12.

15.

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression.

Lucarelli P, Schilling M, Kreutz C, Vlasov A, Boehm ME, Iwamoto N, Steiert B, Lattermann S, Wäsch M, Stepath M, Matter MS, Heikenwälder M, Hoffmann K, Deharde D, Damm G, Seehofer D, Muciek M, Gretz N, Lehmann WD, Timmer J, Klingmüller U.

Cell Syst. 2018 Jan 24;6(1):75-89.e11. doi: 10.1016/j.cels.2017.11.010. Epub 2017 Dec 13.

16.

A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J.

Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11.

PMID:
29227474
17.

Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness.

Wan S, Meyer AS, Weiler SME, Rupp C, Tóth M, Sticht C, Singer S, Thomann S, Roessler S, Schorpp-Kistner M, Schmitt J, Gretz N, Angel P, Tschaharganeh DF, Marquardt J, Schirmacher P, Pinna F, Breuhahn K.

Hepatology. 2018 May;67(5):1842-1856. doi: 10.1002/hep.29669. Epub 2018 Apr 1.

PMID:
29152770
18.

Phenotypic Spectrum of Children with Nephronophthisis and Related Ciliopathies.

König J, Kranz B, König S, Schlingmann KP, Titieni A, Tönshoff B, Habbig S, Pape L, Häffner K, Hansen M, Büscher A, Bald M, Billing H, Schild R, Walden U, Hampel T, Staude H, Riedl M, Gretz N, Lablans M, Bergmann C, Hildebrandt F, Omran H, Konrad M; Gesellschaft für Pädiatrische Nephrologie (GPN).

Clin J Am Soc Nephrol. 2017 Dec 7;12(12):1974-1983. doi: 10.2215/CJN.01280217. Epub 2017 Nov 16.

19.

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.

Sobotta S, Raue A, Huang X, Vanlier J, Jünger A, Bohl S, Albrecht U, Hahnel MJ, Wolf S, Mueller NS, D'Alessandro LA, Mueller-Bohl S, Boehm ME, Lucarelli P, Bonefas S, Damm G, Seehofer D, Lehmann WD, Rose-John S, van der Hoeven F, Gretz N, Theis FJ, Ehlting C, Bode JG, Timmer J, Schilling M, Klingmüller U.

Front Physiol. 2017 Oct 9;8:775. doi: 10.3389/fphys.2017.00775. eCollection 2017.

20.

CTGF Is Expressed During Cystic Remodeling in the PKD/Mhm (cy/+) Rat Model for Autosomal-Dominant Polycystic Kidney Disease (ADPKD).

Gauer S, Holzmann Y, Kränzlin B, Hoffmann SC, Gretz N, Hauser IA, Goppelt-Struebe M, Geiger H, Obermüller N.

J Histochem Cytochem. 2017 Dec;65(12):743-755. doi: 10.1369/0022155417735513. Epub 2017 Oct 23.

21.

[Nonautonomous effects of oncogenic YAP in hepatocarcinogenesis].

Marquard S, Thomann S, Weiler SME, Sticht C, Gretz N, Schirmacher P, Breuhahn K.

Pathologe. 2017 Nov;38(Suppl 2):175-179. doi: 10.1007/s00292-017-0361-2. Review. German.

PMID:
29018944
22.

Light-Emitting Agents for Noninvasive Assessment of Kidney Function.

Huang J, Gretz N.

ChemistryOpen. 2017 Jul 20;6(4):456-471. doi: 10.1002/open.201700065. eCollection 2017 Aug. Review.

23.

A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage.

Niopek K, Üstünel BE, Seitz S, Sakurai M, Zota A, Mattijssen F, Wang X, Sijmonsma T, Feuchter Y, Gail AM, Leuchs B, Niopek D, Staufer O, Brune M, Sticht C, Gretz N, Müller-Decker K, Hammes HP, Nawroth P, Fleming T, Conkright MD, Blüher M, Zeigerer A, Herzig S, Berriel Diaz M.

Cell Rep. 2017 Aug 8;20(6):1422-1434. doi: 10.1016/j.celrep.2017.07.023.

24.

Non-contact Raman spectroscopy for in-line monitoring of glucose and ethanol during yeast fermentations.

Schalk R, Braun F, Frank R, Rädle M, Gretz N, Methner FJ, Beuermann T.

Bioprocess Biosyst Eng. 2017 Oct;40(10):1519-1527. doi: 10.1007/s00449-017-1808-9. Epub 2017 Jun 27.

PMID:
28656375
25.

Zwitterionic near infrared fluorescent agents for noninvasive real-time transcutaneous assessment of kidney function.

Huang J, Weinfurter S, Daniele C, Perciaccante R, Federica R, Della Ciana L, Pill J, Gretz N.

Chem Sci. 2017 Apr 1;8(4):2652-2660. doi: 10.1039/c6sc05059j. Epub 2017 Jan 11.

26.

Combining new tools to assess renal function and morphology: a holistic approach to study the effects of aging and a congenital nephron deficit.

Geraci S, Chacon-Caldera J, Cullen-McEwen L, Schad LR, Sticht C, Puelles VG, Bertram JF, Gretz N.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F576-F584. doi: 10.1152/ajprenal.00329.2015. Epub 2017 May 10.

27.

A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle.

Buscone S, Mardaryev AN, Raafs B, Bikker JW, Sticht C, Gretz N, Farjo N, Uzunbajakava NE, Botchkareva NV.

Lasers Surg Med. 2017 Sep;49(7):705-718. doi: 10.1002/lsm.22673. Epub 2017 Apr 18.

PMID:
28418107
28.

Human Kidney-Derived Cells Ameliorate Acute Kidney Injury Without Engrafting into Renal Tissue.

Santeramo I, Herrera Perez Z, Illera A, Taylor A, Kenny S, Murray P, Wilm B, Gretz N.

Stem Cells Transl Med. 2017 May;6(5):1373-1384. doi: 10.1002/sctm.16-0352. Epub 2017 Apr 4.

29.

Assessment of acute kidney injury in rhabdomyolytic mice by transcutaneous measurement of sinistrin excretion.

Moggio A, Geraci S, Boido A, Sticht C, Gretz N, Bussolati B.

Nephrol Dial Transplant. 2017 Jul 1;32(7):1167-1175. doi: 10.1093/ndt/gfw438.

PMID:
28340139
30.

Hyperosmolarity impedes the cross-priming competence of dendritic cells in a TRIF-dependent manner.

Popovic ZV, Embgenbroich M, Chessa F, Nordström V, Bonrouhi M, Hielscher T, Gretz N, Wang S, Mathow D, Quast T, Schloetel JG, Kolanus W, Burgdorf S, Gröne HJ.

Sci Rep. 2017 Mar 22;7(1):311. doi: 10.1038/s41598-017-00434-y.

31.

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

Weiler SME, Pinna F, Wolf T, Lutz T, Geldiyev A, Sticht C, Knaub M, Thomann S, Bissinger M, Wan S, Rössler S, Becker D, Gretz N, Lang H, Bergmann F, Ustiyan V, Kalin TV, Singer S, Lee JS, Marquardt JU, Schirmacher P, Kalinichenko VV, Breuhahn K.

Gastroenterology. 2017 Jun;152(8):2037-2051.e22. doi: 10.1053/j.gastro.2017.02.018. Epub 2017 Feb 27.

PMID:
28249813
32.

Circulating fibronectin contributes to mesangial expansion in a murine model of type 1 diabetes.

Klemis V, Ghura H, Federico G, Würfel C, Bentmann A, Gretz N, Miyazaki T, Gröne HJ, Nakchbandi IA.

Kidney Int. 2017 Jun;91(6):1374-1385. doi: 10.1016/j.kint.2016.12.006. Epub 2017 Jan 31.

PMID:
28159318
33.

TTCA: an R package for the identification of differentially expressed genes in time course microarray data.

Albrecht M, Stichel D, Müller B, Merkle R, Sticht C, Gretz N, Klingmüller U, Breuhahn K, Matthäus F.

BMC Bioinformatics. 2017 Jan 14;18(1):33. doi: 10.1186/s12859-016-1440-8.

34.

Control of diabetic hyperglycaemia and insulin resistance through TSC22D4.

Ekim Üstünel B, Friedrich K, Maida A, Wang X, Krones-Herzig A, Seibert O, Sommerfeld A, Jones A, Sijmonsma TP, Sticht C, Gretz N, Fleming T, Nawroth PP, Stremmel W, Rose AJ, Berriel-Diaz M, Blüher M, Herzig S.

Nat Commun. 2016 Nov 9;7:13267. doi: 10.1038/ncomms13267.

35.

A Novel Murine Model of Parvovirus Associated Dilated Cardiomyopathy Induced by Immunization with VP1-Unique Region of Parvovirus B19.

Bogomolovas J, Šimoliūnas E, Rinkūnaitė I, Smalinskaitė L, Podkopajev A, Bironaitė D, Weis CA, Marx A, Bukelskienė V, Gretz N, Grabauskienė V, Labeit D, Labeit S.

Biomed Res Int. 2016;2016:1627184. Epub 2016 Oct 12.

36.

Maternal glucose intolerance reduces offspring nephron endowment and increases glomerular volume in adult offspring.

Hokke S, Arias N, Armitage JA, Puelles VG, Fong K, Geraci S, Gretz N, Bertram JF, Cullen-McEwen LA.

Diabetes Metab Res Rev. 2016 Nov;32(8):816-826. doi: 10.1002/dmrr.2805. Epub 2016 May 3.

PMID:
27037899
37.

Assessing the potential of pharmaceuticals and their transformation products to cause mutagenic effects: Implications for gene expression profiling.

Vasquez MI, Tarapoulouzi M, Lambrianides N, Hapeshi E, Felekkis K, Saile M, Sticht C, Gretz N, Fatta-Kassinos D.

Environ Toxicol Chem. 2016 Nov;35(11):2753-2764. doi: 10.1002/etc.3444. Epub 2016 Jul 7.

PMID:
27043355
38.

Fluorescently Labeled Cyclodextrin Derivatives as Exogenous Markers for Real-Time Transcutaneous Measurement of Renal Function.

Huang J, Weinfurter S, Pinto PC, Pretze M, Kränzlin B, Pill J, Federica R, Perciaccante R, Ciana LD, Masereeuw R, Gretz N.

Bioconjug Chem. 2016 Oct 19;27(10):2513-2526. Epub 2016 Sep 22.

PMID:
27611623
39.

System analysis of metabolism and the transcriptome in Arabidopsis thaliana roots reveals differential co-regulation upon iron, sulfur and potassium deficiency.

Forieri I, Sticht C, Reichelt M, Gretz N, Hawkesford MJ, Malagoli M, Wirtz M, Hell R.

Plant Cell Environ. 2017 Jan;40(1):95-107. doi: 10.1111/pce.12842. Epub 2016 Nov 28.

PMID:
27726154
40.

Gene expression profiling reveals aryl hydrocarbon receptor as a possible target for photobiomodulation when using blue light.

Becker A, Klapczynski A, Kuch N, Arpino F, Simon-Keller K, De La Torre C, Sticht C, van Abeelen FA, Oversluizen G, Gretz N.

Sci Rep. 2016 Sep 27;6:33847. doi: 10.1038/srep33847.

41.

Highly Sensitive Raman Spectroscopy with Low Laser Power for Fast In-Line Reaction and Multiphase Flow Monitoring.

Braun F, Schwolow S, Seltenreich J, Kockmann N, Röder T, Gretz N, Rädle M.

Anal Chem. 2016 Oct 4;88(19):9368-9374. Epub 2016 Sep 22.

PMID:
27603732
42.

Obtaining miRNA-Target Interaction Information from miRWalk2.0.

Parveen A, Gretz N, Dweep H.

Curr Protoc Bioinformatics. 2016 Sep 7;55:12.15.1-12.15.27. doi: 10.1002/cpbi.14.

PMID:
27603021
43.

Filtration markers and determination methods for the assessment of kidney function.

Huang J, Gretz N, Weinfurter S.

Eur J Pharmacol. 2016 Nov 5;790:92-98. doi: 10.1016/j.ejphar.2016.06.060. Epub 2016 Jul 1. Review.

PMID:
27377216
44.

A Comprehensive Review on the Genetic Regulation of Cisplatin-induced Nephrotoxicity.

Herrera-Pérez Z, Gretz N, Dweep H.

Curr Genomics. 2016 Jun;17(3):279-93. doi: 10.2174/1389202917666160202220555.

45.

Kidney Injury Molecule-1 Is Specifically Expressed in Cystically-Transformed Proximal Tubules of the PKD/Mhm (cy/+) Rat Model of Polycystic Kidney Disease.

Gauer S, Urbschat A, Gretz N, Hoffmann SC, Kränzlin B, Geiger H, Obermüller N.

Int J Mol Sci. 2016 May 24;17(6). pii: E802. doi: 10.3390/ijms17060802.

46.

Transcutaneous Assessment of Renal Function in Conscious Rodents.

Herrera Pérez Z, Weinfurter S, Gretz N.

J Vis Exp. 2016 Mar 26;(109):e53767. doi: 10.3791/53767.

47.

Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).

Winkler J, Roessler S, Sticht C, DiGuilio AL, Drucker E, Holzer K, Eiteneuer E, Herpel E, Breuhahn K, Gretz N, Schirmacher P, Ori A, Singer S.

Oncotarget. 2016 Apr 19;7(16):22883-92. doi: 10.18632/oncotarget.8256.

48.

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.

Schäfer M, Oeing CU, Rohm M, Baysal-Temel E, Lehmann LH, Bauer R, Volz HC, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt MN, Eschenhagen T, Müller-Decker K, Strobel O, Hackert T, Krijgsveld J, Katus HA, Berriel Diaz M, Backs J, Herzig S.

Mol Metab. 2015 Nov 26;5(2):67-78. doi: 10.1016/j.molmet.2015.11.004. eCollection 2016 Feb.

49.

Toxicity study of ochratoxin A using HEK293 and HepG2 cell lines based on microRNA profiling.

Zhao J, Qi X, Dai Q, He X, Dweep H, Guo M, Luo Y, Gretz N, Luo H, Huang K, Xu W.

Hum Exp Toxicol. 2017 Jan;36(1):8-22. doi: 10.1177/0960327116632048. Epub 2016 Jul 11.

PMID:
26893291
50.

Fast glomerular quantification of whole ex vivo mouse kidneys using Magnetic Resonance Imaging at 9.4 Tesla.

Chacon-Caldera J, Geraci S, Krämer P, Cullen-McEwen L, Bertram JF, Gretz N, Schad LR.

Z Med Phys. 2016 Mar;26(1):54-62. doi: 10.1016/j.zemedi.2015.12.008. Epub 2016 Jan 7.

PMID:
26777317

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