Sort by
Items per page

Send to

Choose Destination

Search results

Items: 48


The CNS Immune Landscape from the Viewpoint of a T Cell.

Mundt S, Greter M, Flügel A, Becher B.

Trends Neurosci. 2019 Oct;42(10):667-679. doi: 10.1016/j.tins.2019.07.008. Epub 2019 Aug 29. Review.


Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.

Rauschmeier R, Gustafsson C, Reinhardt A, A-Gonzalez N, Tortola L, Cansever D, Subramanian S, Taneja R, Rossner MJ, Sieweke MH, Greter M, Månsson R, Busslinger M, Kreslavsky T.

EMBO J. 2019 Oct 1;38(19):e101233. doi: 10.15252/embj.2018101233. Epub 2019 Aug 15.


Checking macrophages at the border.

Utz SG, Greter M.

Nat Neurosci. 2019 Jun;22(6):848-850. doi: 10.1038/s41593-019-0411-6. No abstract available.


Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation.

Mundt S, Mrdjen D, Utz SG, Greter M, Schreiner B, Becher B.

Sci Immunol. 2019 Jan 25;4(31). pii: eaau8380. doi: 10.1126/sciimmunol.aau8380.


Trained Microglia Trigger Memory Loss.

Lelios I, Greter M.

Immunity. 2018 May 15;48(5):849-851. doi: 10.1016/j.immuni.2018.04.033.


High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.

Mrdjen D, Pavlovic A, Hartmann FJ, Schreiner B, Utz SG, Leung BP, Lelios I, Heppner FL, Kipnis J, Merkler D, Greter M, Becher B.

Immunity. 2018 Mar 20;48(3):599. doi: 10.1016/j.immuni.2018.02.014. No abstract available.


High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.

Mrdjen D, Pavlovic A, Hartmann FJ, Schreiner B, Utz SG, Leung BP, Lelios I, Heppner FL, Kipnis J, Merkler D, Greter M, Becher B.

Immunity. 2018 Feb 20;48(2):380-395.e6. doi: 10.1016/j.immuni.2018.01.011. Epub 2018 Feb 6. Erratum in: Immunity. 2018 Mar 20;48(3):599.


Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner.

Thion MS, Low D, Silvin A, Chen J, Grisel P, Schulte-Schrepping J, Blecher R, Ulas T, Squarzoni P, Hoeffel G, Coulpier F, Siopi E, David FS, Scholz C, Shihui F, Lum J, Amoyo AA, Larbi A, Poidinger M, Buttgereit A, Lledo PM, Greter M, Chan JKY, Amit I, Beyer M, Schultze JL, Schlitzer A, Pettersson S, Ginhoux F, Garel S.

Cell. 2018 Jan 25;172(3):500-516.e16. doi: 10.1016/j.cell.2017.11.042. Epub 2017 Dec 21.


The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages.

Yu X, Buttgereit A, Lelios I, Utz SG, Cansever D, Becher B, Greter M.

Immunity. 2017 Nov 21;47(5):903-912.e4. doi: 10.1016/j.immuni.2017.10.007. Epub 2017 Nov 7.


EMPhasis on Mutant Microglia: Dysregulation of Brain Sentinels Induces Neurodegeneration.

Schreiner B, Greter M.

Cell Stem Cell. 2017 Nov 2;21(5):566-568. doi: 10.1016/j.stem.2017.10.006.


Neural precursor cell-secreted TGF-β2 redirects inflammatory monocyte-derived cells in CNS autoimmunity.

De Feo D, Merlini A, Brambilla E, Ottoboni L, Laterza C, Menon R, Srinivasan S, Farina C, Garcia Manteiga JM, Butti E, Bacigaluppi M, Comi G, Greter M, Martino G.

J Clin Invest. 2017 Nov 1;127(11):3937-3953. doi: 10.1172/JCI92387. Epub 2017 Sep 25.


Erratum: Sall1 is a transcriptional regulator defining microglia identity and function.

Buttgereit A, Lelios I, Yu X, Vrohlings M, Krakoski NR, Gautier EL, Nishinakamura R, Becher B, Greter M.

Nat Immunol. 2017 Jan 19;18(2):246. doi: 10.1038/ni0217-246c. No abstract available.


GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation.

Becher B, Tugues S, Greter M.

Immunity. 2016 Nov 15;45(5):963-973. doi: 10.1016/j.immuni.2016.10.026. Review.


Sall1 is a transcriptional regulator defining microglia identity and function.

Buttgereit A, Lelios I, Yu X, Vrohlings M, Krakoski NR, Gautier EL, Nishinakamura R, Becher B, Greter M.

Nat Immunol. 2016 Dec;17(12):1397-1406. doi: 10.1038/ni.3585. Epub 2016 Oct 24. Erratum in: Nat Immunol. 2017 Jan 19;18(2):246.


Family ties among CNS macrophages.

Greter M.

Nat Immunol. 2016 Jun 21;17(7):742-3. doi: 10.1038/ni.3490. No abstract available.


Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems.

Waisman A, Ginhoux F, Greter M, Bruttger J.

Trends Immunol. 2015 Oct;36(10):625-636. doi: 10.1016/ Review.


The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.

Croxford AL, Lanzinger M, Hartmann FJ, Schreiner B, Mair F, Pelczar P, Clausen BE, Jung S, Greter M, Becher B.

Immunity. 2015 Sep 15;43(3):502-14. doi: 10.1016/j.immuni.2015.08.010. Epub 2015 Sep 1.


Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation.

Greter M, Lelios I, Croxford AL.

Front Immunol. 2015 May 26;6:249. doi: 10.3389/fimmu.2015.00249. eCollection 2015. Review.


C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages.

Hoeffel G, Chen J, Lavin Y, Low D, Almeida FF, See P, Beaudin AE, Lum J, Low I, Forsberg EC, Poidinger M, Zolezzi F, Larbi A, Ng LG, Chan JK, Greter M, Becher B, Samokhvalov IM, Merad M, Ginhoux F.

Immunity. 2015 Apr 21;42(4):665-78. doi: 10.1016/j.immuni.2015.03.011.


Neutralization of colony-stimulating factor 1 receptor prevents sickness behavior syndrome by reprogramming inflammatory monocytes to produce IL-10.

Müller AF, Strauss L, Greter M, Gast H, Recher M, Becher B, Fontana A.

Brain Behav Immun. 2015 Aug;48:78-85. doi: 10.1016/j.bbi.2015.02.027. Epub 2015 Mar 4.


Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex.

Arnò B, Grassivaro F, Rossi C, Bergamaschi A, Castiglioni V, Furlan R, Greter M, Favaro R, Comi G, Becher B, Martino G, Muzio L.

Nat Commun. 2014 Nov 26;5:5611. doi: 10.1038/ncomms6611.


High-dimensional analysis of the murine myeloid cell system.

Becher B, Schlitzer A, Chen J, Mair F, Sumatoh HR, Teng KW, Low D, Ruedl C, Riccardi-Castagnoli P, Poidinger M, Greter M, Ginhoux F, Newell EW.

Nat Immunol. 2014 Dec;15(12):1181-9. doi: 10.1038/ni.3006. Epub 2014 Oct 12.


Isolation of leukocytes from mouse central nervous system.

Lelios I, Greter M.

Methods Mol Biol. 2014;1193:15-9. doi: 10.1007/978-1-4939-1212-4_2.


Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes.

Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, van Rooijen N, García-Sastre A, Stanley ER, Ginhoux F, Frenette PS, Merad M.

Immunity. 2013 Apr 18;38(4):792-804. doi: 10.1016/j.immuni.2013.04.004.


Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia.

Greter M, Lelios I, Pelczar P, Hoeffel G, Price J, Leboeuf M, Kündig TM, Frei K, Ginhoux F, Merad M, Becher B.

Immunity. 2012 Dec 14;37(6):1050-1060. doi: 10.1016/j.immuni.2012.11.001. Epub 2012 Nov 21.


Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease.

Codarri L, Greter M, Becher B.

Trends Immunol. 2013 Mar;34(3):114-9. doi: 10.1016/ Epub 2012 Oct 29. Review.


Acquitting an APC: DCs found "not guilty" after trial by ablation.

Becher B, Greter M.

Eur J Immunol. 2012 Oct;42(10):2551-4. doi: 10.1002/eji.201242928.


Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages.

Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, Helft J, Chow A, Elpek KG, Gordonov S, Mazloom AR, Ma'ayan A, Chua WJ, Hansen TH, Turley SJ, Merad M, Randolph GJ; Immunological Genome Consortium.

Nat Immunol. 2012 Nov;13(11):1118-28. doi: 10.1038/ni.2419. Epub 2012 Sep 30.


Regulation of microglia development and homeostasis.

Greter M, Merad M.

Glia. 2013 Jan;61(1):121-7. doi: 10.1002/glia.22408. Epub 2012 Aug 27. Review.


Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity.

Gautier EL, Chow A, Spanbroek R, Marcelin G, Greter M, Jakubzick C, Bogunovic M, Leboeuf M, van Rooijen N, Habenicht AJ, Merad M, Randolph GJ.

J Immunol. 2012 Sep 1;189(5):2614-24. doi: 10.4049/jimmunol.1200495. Epub 2012 Aug 1.


Deciphering the transcriptional network of the dendritic cell lineage.

Miller JC, Brown BD, Shay T, Gautier EL, Jojic V, Cohain A, Pandey G, Leboeuf M, Elpek KG, Helft J, Hashimoto D, Chow A, Price J, Greter M, Bogunovic M, Bellemare-Pelletier A, Frenette PS, Randolph GJ, Turley SJ, Merad M; Immunological Genome Consortium.

Nat Immunol. 2012 Sep;13(9):888-99. doi: 10.1038/ni.2370. Epub 2012 Jul 15.


GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells.

Greter M, Helft J, Chow A, Hashimoto D, Mortha A, Agudo-Cantero J, Bogunovic M, Gautier EL, Miller J, Leboeuf M, Lu G, Aloman C, Brown BD, Pollard JW, Xiong H, Randolph GJ, Chipuk JE, Frenette PS, Merad M.

Immunity. 2012 Jun 29;36(6):1031-46. doi: 10.1016/j.immuni.2012.03.027.


Antigen-presenting cell-derived complement modulates graft-versus-host disease.

Kwan WH, Hashimoto D, Paz-Artal E, Ostrow K, Greter M, Raedler H, Medof ME, Merad M, Heeger PS.

J Clin Invest. 2012 Jun;122(6):2234-8. doi: 10.1172/JCI61019. Epub 2012 May 15.


Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages.

Hoeffel G, Wang Y, Greter M, See P, Teo P, Malleret B, Leboeuf M, Low D, Oller G, Almeida F, Choy SH, Grisotto M, Renia L, Conway SJ, Stanley ER, Chan JK, Ng LG, Samokhvalov IM, Merad M, Ginhoux F.

J Exp Med. 2012 Jun 4;209(6):1167-81. doi: 10.1084/jem.20120340. Epub 2012 May 7.


Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine.

Lewis KL, Caton ML, Bogunovic M, Greter M, Grajkowska LT, Ng D, Klinakis A, Charo IF, Jung S, Gommerman JL, Ivanov II, Liu K, Merad M, Reizis B.

Immunity. 2011 Nov 23;35(5):780-91. doi: 10.1016/j.immuni.2011.08.013. Epub 2011 Oct 20.


NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses.

Hofmann J, Mair F, Greter M, Schmidt-Supprian M, Becher B.

J Exp Med. 2011 Aug 29;208(9):1917-29. doi: 10.1084/jem.20110128. Epub 2011 Aug 1.


Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation.

Hashimoto D, Chow A, Greter M, Saenger Y, Kwan WH, Leboeuf M, Ginhoux F, Ochando JC, Kunisaki Y, van Rooijen N, Liu C, Teshima T, Heeger PS, Stanley ER, Frenette PS, Merad M.

J Exp Med. 2011 May 9;208(5):1069-82. doi: 10.1084/jem.20101709. Epub 2011 May 2.


CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system.

Prodinger C, Bunse J, Krüger M, Schiefenhövel F, Brandt C, Laman JD, Greter M, Immig K, Heppner F, Becher B, Bechmann I.

Acta Neuropathol. 2011 Apr;121(4):445-58. doi: 10.1007/s00401-010-0774-y. Epub 2010 Nov 13.


Fate mapping analysis reveals that adult microglia derive from primitive macrophages.

Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, Mehler MF, Conway SJ, Ng LG, Stanley ER, Samokhvalov IM, Merad M.

Science. 2010 Nov 5;330(6005):841-5. doi: 10.1126/science.1194637. Epub 2010 Oct 21.


Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling.

Sathaliyawala T, O'Gorman WE, Greter M, Bogunovic M, Konjufca V, Hou ZE, Nolan GP, Miller MJ, Merad M, Reizis B.

Immunity. 2010 Oct 29;33(4):597-606. doi: 10.1016/j.immuni.2010.09.012. Epub 2010 Oct 7.


B-cells need a proper house, whereas T-cells are happy in a cave: the dependence of lymphocytes on secondary lymphoid tissues during evolution.

Hofmann J, Greter M, Du Pasquier L, Becher B.

Trends Immunol. 2010 Apr;31(4):144-53. doi: 10.1016/ Epub 2010 Feb 22. Review.


The origin and development of nonlymphoid tissue CD103+ DCs.

Ginhoux F, Liu K, Helft J, Bogunovic M, Greter M, Hashimoto D, Price J, Yin N, Bromberg J, Lira SA, Stanley ER, Nussenzweig M, Merad M.

J Exp Med. 2009 Dec 21;206(13):3115-30. doi: 10.1084/jem.20091756. Epub 2009 Dec 14.


Origin of the lamina propria dendritic cell network.

Bogunovic M, Ginhoux F, Helft J, Shang L, Hashimoto D, Greter M, Liu K, Jakubzick C, Ingersoll MA, Leboeuf M, Stanley ER, Nussenzweig M, Lira SA, Randolph GJ, Merad M.

Immunity. 2009 Sep 18;31(3):513-25. doi: 10.1016/j.immuni.2009.08.010. Epub 2009 Sep 10.


Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity.

Greter M, Hofmann J, Becher B.

PLoS Biol. 2009 May 5;7(5):e1000109. doi: 10.1371/journal.pbio.1000109. Epub 2009 May 26.


The Fas pathway is involved in pancreatic beta cell secretory function.

Schumann DM, Maedler K, Franklin I, Konrad D, Størling J, Böni-Schnetzler M, Gjinovci A, Kurrer MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, Halban PA, Mandrup-Poulsen T, Wollheim CB, Donath MY.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2861-6. Epub 2007 Feb 13.


Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain.

Becher B, Bechmann I, Greter M.

J Mol Med (Berl). 2006 Jul;84(7):532-43. Epub 2006 Jun 14. Review.


Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

Greter M, Heppner FL, Lemos MP, Odermatt BM, Goebels N, Laufer T, Noelle RJ, Becher B.

Nat Med. 2005 Mar;11(3):328-34. Epub 2005 Feb 27.


Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

Heppner FL, Greter M, Marino D, Falsig J, Raivich G, Hövelmeyer N, Waisman A, Rülicke T, Prinz M, Priller J, Becher B, Aguzzi A.

Nat Med. 2005 Feb;11(2):146-52. Epub 2005 Jan 23. Erratum in: Nat Med. 2005 Apr;11(4):455.


Supplemental Content

Loading ...
Support Center