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Antiplatelet treatment in acute coronary syndrome patients: Real-world data from the START-Antiplatelet Italian Registry.

Marcucci R, Patti G, Calabrò P, Gori AM, Grossi G, Cirillo P, Pengo V, Gresele P, Pignatelli P, Antonucci E, di Mario C, Valente S, Palareti G.

PLoS One. 2019 Jul 15;14(7):e0219676. doi: 10.1371/journal.pone.0219676. eCollection 2019.


Eltrombopag for the treatment of inherited thrombocytopenias: a phase 2 clinical trial.

Zaninetti C, Gresele P, Bertomoro A, Klersy C, De Candia E, Veneri D, Barozzi S, Fierro T, Alberelli MA, Musella V, Noris P, Fabris F, Balduini CL, Pecci A.

Haematologica. 2019 Jul 4. pii: haematol.2019.223966. doi: 10.3324/haematol.2019.223966. [Epub ahead of print]


Curated disease-causing genes for bleeding, thrombotic, and platelet disorders: Communication from the SSC of the ISTH.

Megy K, Downes K, Simeoni I, Bury L, Morales J, Mapeta R, Bellissimo DB, Bray PF, Goodeve AC, Gresele P, Lambert M, Reitsma P, Ouwehand WH, Freson K; Subcommittee on Genomics in Thrombosis and Hemostasis.

J Thromb Haemost. 2019 Aug;17(8):1253-1260. doi: 10.1111/jth.14479. Epub 2019 Jun 9. No abstract available.


Nitric oxide-enhancing or -releasing agents as antithrombotic drugs.

Gresele P, Momi S, Guglielmini G.

Biochem Pharmacol. 2019 Aug;166:300-312. doi: 10.1016/j.bcp.2019.05.030. Epub 2019 Jun 4. Review.


Eltrombopag in preparation for surgery in patients with severe MYH9-related thrombocytopenia.

Zaninetti C, Barozzi S, Bozzi V, Gresele P, Balduini CL, Pecci A.

Am J Hematol. 2019 Aug;94(8):E199-E201. doi: 10.1002/ajh.25500. Epub 2019 May 8. No abstract available.


A phase III study comparing secondary long-term prophylaxis versus on-demand treatment with vWF/FVIII concentrates in severe inherited von Willebrand disease.

Peyvandi F, Castaman G, Gresele P, De Cristofaro R, Schinco P, Bertomoro A, Morfini M, Gamba G, Barillari G, Jiménez-Yuste V, Königs C, Iorio A, Federici AB.

Blood Transfus. 2019 Feb 4:1-8. doi: 10.2450/2019.0183-18. [Epub ahead of print]


Inhibition of platelet function after ocular administration of non-steroidal anti-inflammatory drugs.

Falcinelli E, Iannone A, Mezzasoma AM, Amato L, Fierro T, Guglielmini G, Cagini C, Gresele P.

Thromb Res. 2019 Mar;175:1-5. doi: 10.1016/j.thromres.2019.01.005. Epub 2019 Jan 11.


Mechanisms of thrombocytopenia in platelet-type von Willebrand disease.

Bury L, Malara A, Momi S, Petito E, Balduini A, Gresele P.

Haematologica. 2019 Jul;104(7):1473-1481. doi: 10.3324/haematol.2018.200378. Epub 2019 Jan 17.


PCSK9 in Haemostasis and Thrombosis: Possible Pleiotropic Effects of PCSK9 Inhibitors in Cardiovascular Prevention.

Paciullo F, Momi S, Gresele P.

Thromb Haemost. 2019 Mar;119(3):359-367. doi: 10.1055/s-0038-1676863. Epub 2019 Jan 3. Review.


Platelet function assays in diagnosis: an update.

Gresele P, Bury L, Mezzasoma AM, Falcinelli E.

Expert Rev Hematol. 2019 Jan;12(1):29-46. doi: 10.1080/17474086.2019.1562333. Epub 2019 Jan 16.


Of mice and men: genes relevant to thrombosis and bleeding.

Gresele P, Bury L.

Blood. 2018 Dec 13;132(24):2532-2534. doi: 10.1182/blood-2018-10-879700. No abstract available.


A dichotomy in platelet activation: Evidence of different functional platelet responses to inflammatory versus haemostatic stimuli.

Petito E, Amison RT, Piselli E, Shah SA, Momi S, Pitchford SC, Gresele P, Page CP.

Thromb Res. 2018 Dec;172:110-118. doi: 10.1016/j.thromres.2018.10.019. Epub 2018 Oct 25.


Effect of statins on measures of coagulation: potential role of low-density lipoprotein receptors.

Paciullo F, Gresele P.

Eur Heart J. 2019 Jan 21;40(4):392. doi: 10.1093/eurheartj/ehy680. No abstract available.


Laboratory monitoring of P2Y12 inhibitors: communication from the SSC of the ISTH.

Frelinger AL 3rd, Gachet C, Mumford AD, Noris P, Mezzano D, Harrison P, Gresele P; Subcommittee on Platelet Physiology.

J Thromb Haemost. 2018 Nov;16(11):2341-2346. doi: 10.1111/jth.14282. Epub 2018 Oct 3. No abstract available.


Bioactive lipid metabolism in platelet "first responder" and cancer biology.

Kanikarla-Marie P, Kopetz S, Hawk ET, Millward SW, Sood AK, Gresele P, Overman M, Honn K, Menter DG.

Cancer Metastasis Rev. 2018 Sep;37(2-3):439-454. doi: 10.1007/s10555-018-9755-8. Review.


Impact of Chronic Renal Failure on Ischemic and Bleeding Events at 1 Year in Patients With Acute Coronary Syndrome (from the Multicenter START ANTIPLATELET Registry).

Patti G, Ricottini E, Nenna A, Cavallari I, Antonucci E, Calabrò P, Cirillo P, Gresele P, Palareti G, Pengo V, Pignatelli P, Bisignani A, Marcucci R.

Am J Cardiol. 2018 Sep 15;122(6):936-943. doi: 10.1016/j.amjcard.2018.05.049. Epub 2018 Jun 27.


Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome.

Pengo V, Denas G, Zoppellaro G, Jose SP, Hoxha A, Ruffatti A, Andreoli L, Tincani A, Cenci C, Prisco D, Fierro T, Gresele P, Cafolla A, De Micheli V, Ghirarduzzi A, Tosetto A, Falanga A, Martinelli I, Testa S, Barcellona D, Gerosa M, Banzato A.

Blood. 2018 Sep 27;132(13):1365-1371. doi: 10.1182/blood-2018-04-848333. Epub 2018 Jul 12.


Gender-Related Differences in Antiplatelet Therapy and Impact on 1-Year Clinical Outcome in Patients Presenting With ACS: The START ANTIPLATELET Registry.

Cirillo P, Di Serafino L, Patti G, Antonucci E, Calabrò P, Gresele P, Palareti G, Pengo V, Pignatelli P, Marcucci R.

Angiology. 2019 Mar;70(3):257-263. doi: 10.1177/0003319718783866. Epub 2018 Jul 3.


Laboratory diagnosis of clinically relevant platelet function disorders.

Gresele P, Falcinelli E, Bury L.

Int J Lab Hematol. 2018 May;40 Suppl 1:34-45. doi: 10.1111/ijlh.12814. Review.


Anti-platelet treatments in cancer: Basic and clinical research.

Gresele P, Malvestiti M, Momi S.

Thromb Res. 2018 Apr;164 Suppl 1:S106-S111. doi: 10.1016/j.thromres.2017.12.016. Review.


Effect of aspirin treatment on abacavir-associated platelet hyperreactivity in HIV-infected patients.

Falcinelli E, Francisci D, Schiaroli E, Minuz P, Orsini S, Malincarne L, Sebastiano M, Mezzasoma AM, Pasticci MB, Guglielmini G, Baldelli F, Gresele P.

Int J Cardiol. 2018 Jul 15;263:118-124. doi: 10.1016/j.ijcard.2018.04.052. Epub 2018 Apr 12.


Epidemiology and Management of Patients With Acute Coronary Syndromes in Contemporary Real-World Practice: Evolving Trends From the EYESHOT Study to the START-ANTIPLATELET Registry.

Calabrò P, Gragnano F, Di Maio M, Patti G, Antonucci E, Cirillo P, Gresele P, Palareti G, Pengo V, Pignatelli P, Pennacchi M, Granatelli A, De Servi S, De Luca L, Marcucci R; for EYESHOT Study and Start Antiplatelet Register.

Angiology. 2018 Oct;69(9):795-802. doi: 10.1177/0003319718760917. Epub 2018 Mar 15.


Coronary and peripheral artery atherosclerosis: what choice for antiplatelet therapy.

Gresele P.

J Cardiovasc Med (Hagerstown). 2018 Feb;19 Suppl 1:e72-e74. doi: 10.2459/JCM.0000000000000557. Review. No abstract available.


A novel variant Glanzmann thrombasthenia due to co-inheritance of a loss- and a gain-of-function mutation of ITGB3: evidence of a dominant effect of gain-of-function mutations.

Bury L, Zetterberg E, Leinøe EB, Falcinelli E, Marturano A, Manni G, Nurden AT, Gresele P.

Haematologica. 2018 Jun;103(6):e259-e263. doi: 10.3324/haematol.2017.180927. Epub 2018 Feb 8. No abstract available.


Prochemerin cleavage by factor XIa links coagulation and inflammation.

Ge X, Yamaguchi Y, Zhao L, Bury L, Gresele P, Berube C, Leung LL, Morser J.

Blood. 2018 Jan 18;131(3):353-364. doi: 10.1182/blood-2017-07-792580. Epub 2017 Nov 20.


Prevalence and predictors of dual antiplatelet therapy prolongation beyond one year in patients with acute coronary syndrome.

Patti G, Cavallari I, Antonucci E, Calabrò P, Cirillo P, Gresele P, Palareti G, Pengo V, Pignatelli P, Ricottini E, Marcucci R.

PLoS One. 2017 Oct 23;12(10):e0186961. doi: 10.1371/journal.pone.0186961. eCollection 2017.


Platelets Contribute to the Accumulation of Matrix Metalloproteinase Type 2 in Synovial Fluid in Osteoarthritis.

Alunno A, Falcinelli E, Luccioli F, Petito E, Bartoloni E, Momi S, Mirabelli G, Mancini GB, Gerli R, Gresele P.

Thromb Haemost. 2017 Nov;117(11):2116-2124. doi: 10.1160/TH17-06-0379. Epub 2017 Nov 30.


Increase of von Willebrand factor with aging in type 1 von Willebrand disease: fact or fiction?

Borghi M, Guglielmini G, Mezzasoma AM, Falcinelli E, Bury L, Malvestiti M, Gresele P.

Haematologica. 2017 Nov;102(11):e431-e433. doi: 10.3324/haematol.2017.168013. Epub 2017 Jul 27. No abstract available.


Platelet "first responders" in wound response, cancer, and metastasis.

Menter DG, Kopetz S, Hawk E, Sood AK, Loree JM, Gresele P, Honn KV.

Cancer Metastasis Rev. 2017 Jun;36(2):199-213. doi: 10.1007/s10555-017-9682-0. Review.


Platelet-targeted pharmacologic treatments as anti-cancer therapy.

Gresele P, Momi S, Malvestiti M, Sebastiano M.

Cancer Metastasis Rev. 2017 Jun;36(2):331-355. doi: 10.1007/s10555-017-9679-8. Review.


Endothelial activation in patients with superficial vein thrombosis (SVT) of the lower limbs.

Falcinelli E, Cosmi B, Filippini M, Petito E, Legnani C, Cini M, Guglielmini G, Migliacci R, Palareti G, Gresele P.

Thromb Res. 2017 Sep;157:20-22. doi: 10.1016/j.thromres.2017.06.033. Epub 2017 Jun 27. No abstract available.


Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice.

Canobbio I, Visconte C, Momi S, Guidetti GF, Zarà M, Canino J, Falcinelli E, Gresele P, Torti M.

Blood. 2017 Jul 27;130(4):527-536. doi: 10.1182/blood-2017-01-764910. Epub 2017 Jun 13.


Matrix Metalloproteinases and Platelet Function.

Gresele P, Falcinelli E, Sebastiano M, Momi S.

Prog Mol Biol Transl Sci. 2017;147:133-165. doi: 10.1016/bs.pmbts.2017.01.002. Epub 2017 Mar 21. Review.


Bleeding risk of surgery and its prevention in patients with inherited platelet disorders.

Orsini S, Noris P, Bury L, Heller PG, Santoro C, Kadir RA, Butta NC, Falcinelli E, Cid AR, Fabris F, Fouassier M, Miyazaki K, Lozano ML, Zúñiga P, Flaujac C, Podda GM, Bermejo N, Favier R, Henskens Y, De Maistre E, De Candia E, Mumford AD, Ozdemir GN, Eker I, Nurden P, Bayart S, Lambert MP, Bussel J, Zieger B, Tosetto A, Melazzini F, Glembotsky AC, Pecci A, Cattaneo M, Schlegel N, Gresele P; European Hematology Association - Scientific Working Group (EHA-SWG) on thrombocytopenias and platelet function disorders.

Haematologica. 2017 Jul;102(7):1192-1203. doi: 10.3324/haematol.2016.160754. Epub 2017 Apr 6.


A novel mechanism regulating human platelet activation by MMP-2-mediated PAR1 biased signaling.

Sebastiano M, Momi S, Falcinelli E, Bury L, Hoylaerts MF, Gresele P.

Blood. 2017 Feb 16;129(7):883-895. doi: 10.1182/blood-2016-06-724245. Epub 2016 Dec 29.


Inherited platelet function disorders. Diagnostic approach and management.

Gresele P, Falcinelli E, Bury L.

Hamostaseologie. 2016 Nov 7;36(4):265-278. Epub 2016 Aug 3. Review.


Two novel ITGA2B mutations in a Glanzmann thrombasthaenia family associated with different platelet phenotypic expression.

Daidone V, Bury L, Milan M, Galletta E, Gresele P, Casonato A.

Blood Transfus. 2017 Sep;15(5):487-488. doi: 10.2450/2016.0055-16. Epub 2016 Jul 12. No abstract available.


A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.

Simeoni I, Stephens JC, Hu F, Deevi SV, Megy K, Bariana TK, Lentaigne C, Schulman S, Sivapalaratnam S, Vries MJ, Westbury SK, Greene D, Papadia S, Alessi MC, Attwood AP, Ballmaier M, Baynam G, Bermejo E, Bertoli M, Bray PF, Bury L, Cattaneo M, Collins P, Daugherty LC, Favier R, French DL, Furie B, Gattens M, Germeshausen M, Ghevaert C, Goodeve AC, Guerrero JA, Hampshire DJ, Hart DP, Heemskerk JW, Henskens YM, Hill M, Hogg N, Jolley JD, Kahr WH, Kelly AM, Kerr R, Kostadima M, Kunishima S, Lambert MP, Liesner R, López JA, Mapeta RP, Mathias M, Millar CM, Nathwani A, Neerman-Arbez M, Nurden AT, Nurden P, Othman M, Peerlinck K, Perry DJ, Poudel P, Reitsma P, Rondina MT, Smethurst PA, Stevenson W, Szkotak A, Tuna S, van Geet C, Whitehorn D, Wilcox DA, Zhang B, Revel-Vilk S, Gresele P, Bellissimo DB, Penkett CJ, Laffan MA, Mumford AD, Rendon A, Gomez K, Freson K, Ouwehand WH, Turro E.

Blood. 2016 Jun 9;127(23):2791-803. doi: 10.1182/blood-2015-12-688267. Epub 2016 Apr 15.


Inherited Platelet Function Disorders: Algorithms for Phenotypic and Genetic Investigation.

Gresele P, Bury L, Falcinelli E.

Semin Thromb Hemost. 2016 Apr;42(3):292-305. doi: 10.1055/s-0035-1570078. Epub 2016 Mar 10. Review.


Platelet type von Willebrand disease and registry report: communication from the SSC of the ISTH.

Othman M, Kaur H, Favaloro EJ, Lillicrap D, Di Paola J, Harrison P, Gresele P; Subcommittees on von Willebrand Disease and Platelet Physiology.

J Thromb Haemost. 2016 Feb;14(2):411-4. doi: 10.1111/jth.13204. Epub 2016 Jan 20. No abstract available.


First Diagnosis of Hemophilia B in a Nonagenarian.

Bury L, Nardiello P, Fierro T, Zarrilli F, Coppola A, Castaldo G, Gresele P.

J Am Geriatr Soc. 2016 Jan;64(1):230-1. doi: 10.1111/jgs.13898. No abstract available.


Cancers in Patients with von Willebrand Disease: A Survey from the Italian Association of Haemophilia Centres.

Franchini M, Di Perna C, Santoro C, Castaman G, Siboni SM, Zanon E, Linari S, Gresele P, Pasca S, Coppola A, Santoro R, Napolitano M, Ranalli P, Tagliaferri A; Italian Association of Haemophilia Centres.

Semin Thromb Hemost. 2016 Feb;42(1):36-41. doi: 10.1055/s-0035-1564844. Epub 2015 Nov 23.


Matrix metalloproteinase-2 enhances platelet deposition on collagen under flow conditions.

Guglielmini G, Appolloni V, Momi S, De Groot PG, Battiston M, De Marco L, Falcinelli E, Gresele P.

Thromb Haemost. 2016 Jan;115(2):333-43. doi: 10.1160/TH15-04-0300. Epub 2015 Oct 29.


Recurrent Thrombotic Events after Discontinuation of Vitamin K Antagonist Treatment for Splanchnic Vein Thrombosis: A Multicenter Retrospective Cohort Study.

Riva N, Ageno W, Poli D, Testa S, Rupoli S, Santoro R, Lerede T, Piana A, Carpenedo M, Nicolini A, Ferrini PM, Martini G, Mangione C, Contino L, Bonfanti C, Gresele P, Tosetto A.

Gastroenterol Res Pract. 2015;2015:620217. doi: 10.1155/2015/620217. Epub 2015 Oct 5.


Reasons for visits to an emergency center and hemostatic alterations in patients with recurrent spontaneous subconjunctival hemorrhage.

Cagini C, Iannone A, Bartolini A, Fiore T, Fierro T, Gresele P.

Eur J Ophthalmol. 2016 Mar-Apr;26(2):188-92. doi: 10.5301/ejo.5000692. Epub 2015 Oct 14.


Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia.

Bury L, Falcinelli E, Chiasserini D, Springer TA, Italiano JE Jr, Gresele P.

Haematologica. 2016 Jan;101(1):46-56. doi: 10.3324/haematol.2015.130849. Epub 2015 Oct 9.


Nonmuscle Myosin Heavy Chain IIA Mutation Predicts Severity and Progression of Sensorineural Hearing Loss in Patients With MYH9-Related Disease.

Verver EJ, Topsakal V, Kunst HP, Huygen PL, Heller PG, Pujol-Moix N, Savoia A, Benazzo M, Fierro T, Grolman W, Gresele P, Pecci A.

Ear Hear. 2016 Jan-Feb;37(1):112-20. doi: 10.1097/AUD.0000000000000198.


Effect of substituted stilbenes on platelet function.

Messina F, Guglielmini G, Curini M, Orsini S, Gresele P, Marcotullio MC.

Fitoterapia. 2015 Sep;105:228-33. doi: 10.1016/j.fitote.2015.07.009. Epub 2015 Jul 18.


Prevalence of hemostatic alterations in patients with recurrent spontaneous subconjunctival hemorrhage.

Fierro T, Bartolini A, Mezzasoma AM, Guglielmini G, Falcinelli E, Orsini S, Momi S, Cagini C, Gresele P.

Clin Chem Lab Med. 2016 Jan;54(1):97-103. doi: 10.1515/cclm-2015-0274.


A review of platelet secretion assays for the diagnosis of inherited platelet secretion disorders.

Mumford AD, Frelinger AL 3rd, Gachet C, Gresele P, Noris P, Harrison P, Mezzano D.

Thromb Haemost. 2015 Jul;114(1):14-25. doi: 10.1160/TH14-11-0999. Epub 2015 Apr 16. Review.


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