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Items: 50

1.

Highly stable and inert complexation of Indium(III) by reinforced cyclam dipicolinate and a bifunctional derivative for bead encoding in mass cytometry.

Grenier L, Beyler M, Platas-Iglesias C, Closson T, Gómez DE, Seferos DS, Liu P, Ornatsky OI, Baranov V, Tripier R.

Chemistry. 2019 Sep 3. doi: 10.1002/chem.201903969. [Epub ahead of print]

PMID:
31479536
2.

Retinal Complications in Systemic Lupus Erythematosus Patients Treated with Antimalarial Drugs.

Mukwikwi ER, Pineau CA, Vinet E, Clarke AE, Nashi E, Kalache F, Grenier LP, Bernatsky S.

J Rheumatol. 2019 Sep 1. pii: jrheum.181102. doi: 10.3899/jrheum.181102. [Epub ahead of print]

PMID:
31474597
3.

Marital status and age of systemic lupus erythematous diagnosis: the potential for differences related to sex and gender.

Brailovski E, Vinet E, Pineau CA, Lee J, Lukusa L, Kalache F, Grenier LP, DaCosta D, Bernatsky S.

Lupus Sci Med. 2019 Aug 5;6(1):e000325. doi: 10.1136/lupus-2019-000325. eCollection 2019.

4.

Computational drug repurposing for inflammatory bowel disease using genetic information.

Grenier L, Hu P.

Comput Struct Biotechnol J. 2019 Jan 7;17:127-135. doi: 10.1016/j.csbj.2019.01.001. eCollection 2019.

5.

Group versus individual antenatal and first year postpartum care: Study protocol for a multi-country cluster randomized controlled trial in Kenya and Nigeria.

Kabue MM, Grenier L, Suhowatsky S, Oyetunji J, Ugwa E, Onguti B, Omanga E, Gichangi A, Wambua J, Waka C, Enne J, Don-Aki J, Ali M, Buba M, Ang'aha J, Iya D, Washika E, Mohan D, Smith JM.

Gates Open Res. 2018 Nov 5;2:56. doi: 10.12688/gatesopenres.12867.1.

6.

Diffuse pustular eruption following computed tomography.

Levri JM, Grenier LS.

Cutis. 2018 Nov;102(5):E1-E3. No abstract available.

PMID:
30566554
7.

Novel Presentation of Fibroepithelioma of Pinkus on the Ear of a Patient Treated on a Panamanian Humanitarian Mission.

Pollard WL, Grenier LS, Kobayashi TT.

Mil Med. 2018 Nov 1;183(11-12):e751-e753. doi: 10.1093/milmed/usx225.

PMID:
29425357
8.

Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate.

Evans CA, Liu T, Lescarbeau A, Nair SJ, Grenier L, Pradeilles JA, Glenadel Q, Tibbitts T, Rowley AM, DiNitto JP, Brophy EE, O'Hearn EL, Ali JA, Winkler DG, Goldstein SI, O'Hearn P, Martin CM, Hoyt JG, Soglia JR, Cheung C, Pink MM, Proctor JL, Palombella VJ, Tremblay MR, Castro AC.

ACS Med Chem Lett. 2016 Jul 22;7(9):862-7. doi: 10.1021/acsmedchemlett.6b00238. eCollection 2016 Sep 8.

9.

Pain assessment during conscious sedation for cervical cancer high-dose-rate brachytherapy.

Bhanabhai H, Samant R, E C, Grenier L, Lowry S.

Curr Oncol. 2013 Aug;20(4):e307-10. doi: 10.3747/co.20.1404.

10.

Thirty years of global outreach by the American College of Nurse-Midwives.

Kennedy HP, Stalls S, Kaplan LK, Grenier L, Fujioka A.

MCN Am J Matern Child Nurs. 2012 Sep;37(5):290-5; quiz 296-7.

PMID:
22751472
11.

The activation of DNA damage detection and repair responses in cleavage-stage rat embryos by a damaged paternal genome.

Grenier L, Robaire B, Hales BF.

Toxicol Sci. 2012 Jun;127(2):555-66. doi: 10.1093/toxsci/kfs120. Epub 2012 Mar 27.

12.

Paternal cyclophosphamide exposure induces the formation of functional micronuclei during the first zygotic division.

Grenier L, Robaire B, Hales BF.

PLoS One. 2011;6(11):e27600. doi: 10.1371/journal.pone.0027600. Epub 2011 Nov 16.

13.

Epigenetic programming: from gametes to blastocyst.

Hales BF, Grenier L, Lalancette C, Robaire B.

Birth Defects Res A Clin Mol Teratol. 2011 Aug;91(8):652-65. doi: 10.1002/bdra.20781. Epub 2011 Mar 21. Review.

PMID:
21425433
14.

Paternal exposure to cyclophosphamide affects the progression of sperm chromatin decondensation and activates a DNA damage response in the prepronuclear rat zygote.

Grenier L, Robaire B, Hales BF.

Biol Reprod. 2010 Aug 1;83(2):195-204. doi: 10.1095/biolreprod.109.083345. Epub 2010 Apr 14.

15.

Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs.

Messmer M, Blais SP, Balg C, Chênevert R, Grenier L, Lagüe P, Sauter C, Sissler M, Giegé R, Lapointe J, Florentz C.

Biochimie. 2009 May;91(5):596-603. doi: 10.1016/j.biochi.2009.02.005. Epub 2009 Feb 28.

PMID:
19254750
16.

Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.

Tremblay MR, Nevalainen M, Nair SJ, Porter JR, Castro AC, Behnke ML, Yu LC, Hagel M, White K, Faia K, Grenier L, Campbell MJ, Cushing J, Woodward CN, Hoyt J, Foley MA, Read MA, Sydor JR, Tong JK, Palombella VJ, McGovern K, Adams J.

J Med Chem. 2008 Nov 13;51(21):6646-9. doi: 10.1021/jm8008508. Epub 2008 Oct 9.

PMID:
18842035
17.

[Responsibilities of elderly support: normative expectations with regard of ex-spouses and step-children].

Rousseau N, Lavoie JP, Guberman N, Fournier M, Béland F, Grenier L.

Can J Aging. 2008 Winter;27(4):371-83. doi: 10.3138/cja.27.4.371. French.

PMID:
19416798
18.

Families' values and attitudes regarding responsibility for the frail elderly: implications for aging policy.

Guberman N, Lavoie JP, Fournier M, Grenier L, Gagnon E, Belleau H, Vézina A.

J Aging Soc Policy. 2006;18(3-4):59-78.

PMID:
17135095
19.

Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.

Sydor JR, Normant E, Pien CS, Porter JR, Ge J, Grenier L, Pak RH, Ali JA, Dembski MS, Hudak J, Patterson J, Penders C, Pink M, Read MA, Sang J, Woodward C, Zhang Y, Grayzel DS, Wright J, Barrett JA, Palombella VJ, Adams J, Tong JK.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17408-13. Epub 2006 Nov 7.

20.

Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.

Ge J, Normant E, Porter JR, Ali JA, Dembski MS, Gao Y, Georges AT, Grenier L, Pak RH, Patterson J, Sydor JR, Tibbitts TT, Tong JK, Adams J, Palombella VJ.

J Med Chem. 2006 Jul 27;49(15):4606-15.

PMID:
16854066
21.

Varicella vaccination for grades 4 and 5 students: from theory to practice.

Rivest P, Grenier L, Lonergan G, Bédard L.

Can J Public Health. 2005 May-Jun;96(3):197-200.

PMID:
15913084
22.

Novel IKK inhibitors: beta-carbolines.

Castro AC, Dang LC, Soucy F, Grenier L, Mazdiyasni H, Hottelet M, Parent L, Pien C, Palombella V, Adams J.

Bioorg Med Chem Lett. 2003 Jul 21;13(14):2419-22.

PMID:
12824047
23.

Protein-rich diet attenuates cyclosporin A-induced renal tubular damage in rats.

Pons M, Plante I, LeBrun M, Gourde P, Simard M, Grenier L, Thibault L, Labrecque G, Beauchamp D.

J Ren Nutr. 2003 Apr;13(2):84-92.

PMID:
12671830
24.

Multiplex PCR assays for the detection of clinically relevant antibiotic resistance genes in staphylococci isolated from patients infected after cardiac surgery. The ESPRIT Trial.

Martineau F, Picard FJ, Grenier L, Roy PH, Ouellette M, Bergeron MG.

J Antimicrob Chemother. 2000 Oct;46(4):527-34.

PMID:
11020248
25.

Effectiveness and toxicity of gentamicin in an experimental model of pyelonephritis: effect of the time of administration.

LeBrun M, Grenier L, Gourde P, Bergeron MG, Labrecque G, Beauchamp D.

Antimicrob Agents Chemother. 1999 May;43(5):1020-6.

26.

Effect of fasting on temporal variation in the nephrotoxicity of amphotericin B in rats.

LeBrun M, Grenier L, Bergeron MG, Thibault L, Labrecque G, Beauchamp D.

Antimicrob Agents Chemother. 1999 Mar;43(3):520-4.

27.

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids.

Adams J, Behnke M, Chen S, Cruickshank AA, Dick LR, Grenier L, Klunder JM, Ma YT, Plamondon L, Stein RL.

Bioorg Med Chem Lett. 1998 Feb 17;8(4):333-8.

PMID:
9871680
28.
29.

Active site-directed inhibitors of Rhodococcus 20 S proteasome. Kinetics and mechanism.

Mc Cormack T, Baumeister W, Grenier L, Moomaw C, Plamondon L, Pramanik B, Slaughter C, Soucy F, Stein R, Zühl F, Dick L.

J Biol Chem. 1997 Oct 17;272(42):26103-9.

30.

Benefits of distributed HIS/RIS-PACS integration and a proposed architecture.

Keayes RG, Grenier L.

J Digit Imaging. 1997 Aug;10(3 Suppl 1):89-94.

31.

Time-restricted feeding schedules modify temporal variation of gentamicin experimental nephrotoxicity.

Beauchamp D, Guimont C, Grenier L, LeBrun M, Tardif D, Gourde P, Bergeron MG, Thibault L, Labrecque G.

Antimicrob Agents Chemother. 1997 Jul;41(7):1468-74.

32.

Attenuation of gentamicin-induced nephrotoxicity in rats by fleroxacin.

Beauchamp D, Laurent G, Grenier L, Gourde P, Zanen J, Heuson-Stiennon JA, Bergeron MG.

Antimicrob Agents Chemother. 1997 Jun;41(6):1237-45.

33.

Mechanistic studies on the inactivation of the proteasome by lactacystin in cultured cells.

Dick LR, Cruikshank AA, Destree AT, Grenier L, McCormack TA, Melandri FD, Nunes SL, Palombella VJ, Parent LA, Plamondon L, Stein RL.

J Biol Chem. 1997 Jan 3;272(1):182-8.

34.

Kinetic studies on the inhibition of isopeptidase T by ubiquitin aldehyde.

Melandri F, Grenier L, Plamondon L, Huskey WP, Stein RL.

Biochemistry. 1996 Oct 1;35(39):12893-900.

PMID:
8841133
35.

Day-night treatment difference of tobramycin serum and intrarenal drug distribution and nephrotoxicity in rats: effects of fasting.

Lin L, Grenier L, LeBrun M, Bergeron MG, Thibault L, Labrecque G, Beauchamp D.

Chronobiol Int. 1996 Jul;13(2):113-21.

PMID:
8877120
36.

A Practical and Diastereoselective Synthesis of Ketomethylene Dipeptide Isosteres of the Type AAPsi[COCH(2)]Asp.

Déziel R, Plante R, Caron V, Grenier L, Llinas-Brunet M, Duceppe JS, Malenfant E, Moss N.

J Org Chem. 1996 Apr 19;61(8):2901-2903. No abstract available.

PMID:
11667134
37.

Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone.

Dick LR, Cruikshank AA, Grenier L, Melandri FD, Nunes SL, Stein RL.

J Biol Chem. 1996 Mar 29;271(13):7273-6.

38.

Temporal variation in nephrotoxicity of low doses of isepamicin in rats.

Yoshiyama Y, Grenier L, Gourde P, Simard M, Lin L, Morin NJ, Bergeron MG, Labrecque G, Beauchamp D.

Antimicrob Agents Chemother. 1996 Mar;40(3):802-6.

39.

Effects of fasting on temporal variations in nephrotoxicity of gentamicin in rats.

Beauchamp D, Collin P, Grenier L, LeBrun M, Couture M, Thibault L, Labrecque G, Bergeron MG.

Antimicrob Agents Chemother. 1996 Mar;40(3):670-6.

40.

Nephrotoxicity of amphotericin B in rats: effects of the time of administration.

LeBrun M, Grenier L, Gourde P, Bergeron MG, Labrecque G, Beauchamp D.

Life Sci. 1996;58(11):869-76.

PMID:
8786692
41.

Cancer information and resources for Hispanic populations.

Grenier LM.

Cancer Pract. 1995 Sep-Oct;3(5):317-9. No abstract available.

PMID:
7663551
42.

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: a new class of antiviral agents.

Moss N, Beaulieu P, Duceppe JS, Ferland JM, Gauthier J, Ghiro E, Goulet S, Grenier L, Llinas-Brunet M, Plante R, et al.

J Med Chem. 1995 Sep 1;38(18):3617-23.

PMID:
7658449
43.

Current developments in departmental PACS for ultrasound.

Grenier LE, Eng P.

Medinfo. 1995;8 Pt 1:440.

PMID:
8591222
44.

Protection against gentamicin nephrotoxicity by daptomycin in nephrectomized rats.

Thibault N, Grenier L, Simard M, Bergeron MG, Beauchamp D.

Life Sci. 1995;56(22):1877-87.

PMID:
7746096
45.

Attenuation by daptomycin of gentamicin-induced experimental nephrotoxicity.

Thibault N, Grenier L, Simard M, Bergeron MG, Beauchamp D.

Antimicrob Agents Chemother. 1994 May;38(5):1027-35.

46.

Ceftriaxone protects against tobramycin nephrotoxicity.

Beauchamp D, Thériault G, Grenier L, Gourde P, Perron S, Bergeron Y, Fontaine L, Bergeron MG.

Antimicrob Agents Chemother. 1994 Apr;38(4):750-6.

47.

Temporal changes of pharmacokinetics, nephrotoxicity, and subcellular distribution of tobramycin in rats.

Lin L, Grenier L, Bergeron Y, Simard M, Bergeron MG, Labrecque G, Beauchamp D.

Antimicrob Agents Chemother. 1994 Jan;38(1):54-60.

48.

Nephrotoxicity of low doses of tobramycin in rats: effect of the time of administration.

Lin L, Grenier L, Thériault G, Gourde P, Yoshiyama Y, Bergeron MG, Labrecque G, Beauchamp D.

Life Sci. 1994;55(3):169-77.

PMID:
8007759
49.

Synthesis and biological activity of atrial natriuretic factor analogues: effect of modifications to the disulfide bridge.

DiMaio J, Jaramillo J, Wernic D, Grenier L, Welchner E, Adams J.

J Med Chem. 1990 Feb;33(2):661-7.

PMID:
2153824
50.

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