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Items: 34

1.

Ultra-frequent HRAS p.Q61R somatic mutation in canine acanthomatous ameloblastoma reveals pathogenic similarities with human ameloblastoma.

Peralta S, McCleary-Wheeler AL, Duhamel GE, Heikinheimo K, Grenier JK.

Vet Comp Oncol. 2019 May 1. doi: 10.1111/vco.12487. [Epub ahead of print]

PMID:
31041834
2.

The Notch signaling pathway promotes basophil responses during helminth-induced type 2 inflammation.

Webb LM, Oyesola OO, Früh SP, Kamynina E, Still KM, Patel RK, Peng SA, Cubitt RL, Grimson A, Grenier JK, Harris TH, Danko CG, Tait Wojno ED.

J Exp Med. 2019 Jun 3;216(6):1268-1279. doi: 10.1084/jem.20180131. Epub 2019 Apr 11.

PMID:
30975892
3.

Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing.

Grive KJ, Hu Y, Shu E, Grimson A, Elemento O, Grenier JK, Cohen PE.

PLoS Genet. 2019 Mar 20;15(3):e1007810. doi: 10.1371/journal.pgen.1007810. eCollection 2019 Mar.

4.

The degree of postpartum metabolic challenge in dairy cows is associated with peripheral blood mononuclear cell transcriptome changes of the innate immune system.

Mann S, Sipka AS, Grenier JK.

Dev Comp Immunol. 2019 Apr;93:28-36. doi: 10.1016/j.dci.2018.11.021. Epub 2018 Nov 27.

PMID:
30500340
5.

Transcriptome profiling of alphaherpesvirus-infected cells treated with the HIV-integrase inhibitor raltegravir reveals profound and specific alterations in host transcription.

Pennington MR, Grenier JK, Van de Walle GR.

J Gen Virol. 2018 Aug;99(8):1115-1128. doi: 10.1099/jgv.0.001090. Epub 2018 Jun 19.

PMID:
29916804
6.

Developmental Origin Governs CD8+ T Cell Fate Decisions during Infection.

Smith NL, Patel RK, Reynaldi A, Grenier JK, Wang J, Watson NB, Nzingha K, Yee Mon KJ, Peng SA, Grimson A, Davenport MP, Rudd BD.

Cell. 2018 Jun 28;174(1):117-130.e14. doi: 10.1016/j.cell.2018.05.029. Epub 2018 Jun 14.

PMID:
29909981
7.

Temporal changes in macrophage phenotype after peripheral nerve injury.

Tomlinson JE, Žygelytė E, Grenier JK, Edwards MG, Cheetham J.

J Neuroinflammation. 2018 Jun 15;15(1):185. doi: 10.1186/s12974-018-1219-0.

8.

Maternal Choline Supplementation during Normal Murine Pregnancy Alters the Placental Epigenome: Results of an Exploratory Study.

Kwan STC, King JH, Grenier JK, Yan J, Jiang X, Roberson MS, Caudill MA.

Nutrients. 2018 Mar 28;10(4). pii: E417. doi: 10.3390/nu10040417.

9.

Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia.

Sones JL, Merriam AA, Seffens A, Brown-Grant DA, Butler SD, Zhao AM, Xu X, Shawber CJ, Grenier JK, Douglas NC.

FASEB J. 2018 May;32(5):2574-2586. doi: 10.1096/fj.201701008R. Epub 2018 Jan 8.

10.

RNA-seq transcriptome analysis of formalin fixed, paraffin-embedded canine meningioma.

Grenier JK, Foureman PA, Sloma EA, Miller AD.

PLoS One. 2017 Oct 26;12(10):e0187150. doi: 10.1371/journal.pone.0187150. eCollection 2017.

11.

XX Disorder of Sex Development is associated with an insertion on chromosome 9 and downregulation of RSPO1 in dogs (Canis lupus familiaris).

Meyers-Wallen VN, Boyko AR, Danko CG, Grenier JK, Mezey JG, Hayward JJ, Shannon LM, Gao C, Shafquat A, Rice EJ, Pujar S, Eggers S, Ohnesorg T, Sinclair AH.

PLoS One. 2017 Oct 20;12(10):e0186331. doi: 10.1371/journal.pone.0186331. eCollection 2017.

12.

Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure.

Moon H, Donahue LR, Choi E, Scumpia PO, Lowry WE, Grenier JK, Zhu J, White AC.

Cell Stem Cell. 2017 Nov 2;21(5):665-678.e6. doi: 10.1016/j.stem.2017.09.001. Epub 2017 Oct 12.

13.

SIRT7 Is an RNA-Activated Protein Lysine Deacylase.

Tong Z, Wang M, Wang Y, Kim DD, Grenier JK, Cao J, Sadhukhan S, Hao Q, Lin H.

ACS Chem Biol. 2017 Jan 20;12(1):300-310. doi: 10.1021/acschembio.6b00954. Epub 2016 Dec 20.

14.

Survey of Global Genetic Diversity Within the Drosophila Immune System.

Early AM, Arguello JR, Cardoso-Moreira M, Gottipati S, Grenier JK, Clark AG.

Genetics. 2017 Jan;205(1):353-366. doi: 10.1534/genetics.116.195016. Epub 2016 Nov 4.

15.

Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion.

Arguello JR, Cardoso-Moreira M, Grenier JK, Gottipati S, Clark AG, Benton R.

Nat Commun. 2016 Jun 13;7:ncomms11855. doi: 10.1038/ncomms11855.

16.

Evidence for the fixation of gene duplications by positive selection in Drosophila.

Cardoso-Moreira M, Arguello JR, Gottipati S, Harshman LG, Grenier JK, Clark AG.

Genome Res. 2016 Jun;26(6):787-98. doi: 10.1101/gr.199323.115. Epub 2016 Apr 12.

17.

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.

Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA.

Mol Ther. 2015 Sep;23(9):1465-74. doi: 10.1038/mt.2015.113. Epub 2015 Jun 17.

18.

Behavioral idiosyncrasy reveals genetic control of phenotypic variability.

Ayroles JF, Buchanan SM, O'Leary C, Skutt-Kakaria K, Grenier JK, Clark AG, Hartl DL, de Bivort BL.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6706-11. doi: 10.1073/pnas.1503830112. Epub 2015 May 7.

19.

Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males.

Modzelewski AJ, Hilz S, Crate EA, Schweidenback CT, Fogarty EA, Grenier JK, Freire R, Cohen PE, Grimson A.

J Cell Sci. 2015 Jun 15;128(12):2314-27. doi: 10.1242/jcs.167148. Epub 2015 May 1.

20.

Global diversity lines - a five-continent reference panel of sequenced Drosophila melanogaster strains.

Grenier JK, Arguello JR, Moreira MC, Gottipati S, Mohammed J, Hackett SR, Boughton R, Greenberg AJ, Clark AG.

G3 (Bethesda). 2015 Feb 11;5(4):593-603. doi: 10.1534/g3.114.015883.

21.

Correlated variation and population differentiation in satellite DNA abundance among lines of Drosophila melanogaster.

Wei KH, Grenier JK, Barbash DA, Clark AG.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18793-8. doi: 10.1073/pnas.1421951112. Epub 2014 Dec 15.

22.

Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks.

Wagner JP, Wolf-Yadlin A, Sevecka M, Grenier JK, Root DE, Lauffenburger DA, MacBeath G.

Sci Signal. 2013 Jul 16;6(284):ra58. doi: 10.1126/scisignal.2003994.

23.

lincRNAs act in the circuitry controlling pluripotency and differentiation.

Guttman M, Donaghey J, Carey BW, Garber M, Grenier JK, Munson G, Young G, Lucas AB, Ach R, Bruhn L, Yang X, Amit I, Meissner A, Regev A, Rinn JL, Root DE, Lander ES.

Nature. 2011 Aug 28;477(7364):295-300. doi: 10.1038/nature10398.

24.

A comprehensive platform for highly multiplexed mammalian functional genetic screens.

Ketela T, Heisler LE, Brown KR, Ammar R, Kasimer D, Surendra A, Ericson E, Blakely K, Karamboulas D, Smith AM, Durbic T, Arnoldo A, Cheung-Ong K, Koh JL, Gopal S, Cowley GS, Yang X, Grenier JK, Giaever G, Root DE, Moffat J, Nislow C.

BMC Genomics. 2011 May 6;12:213. doi: 10.1186/1471-2164-12-213.

25.

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses.

Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A.

Science. 2009 Oct 9;326(5950):257-63. doi: 10.1126/science.1179050. Epub 2009 Sep 3.

26.

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning.

Jones TR, Carpenter AE, Lamprecht MR, Moffat J, Silver SJ, Grenier JK, Castoreno AB, Eggert US, Root DE, Golland P, Sabatini DM.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1826-31. doi: 10.1073/pnas.0808843106. Epub 2009 Feb 2.

27.

Integrative genomic approaches identify IKBKE as a breast cancer oncogene.

Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC.

Cell. 2007 Jun 15;129(6):1065-79.

28.

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.

Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE.

Cell. 2006 Mar 24;124(6):1283-98.

29.

Exploiting the enzymatic recognition of an unnatural base pair to develop a universal genetic analysis system.

Moser MJ, Marshall DJ, Grenier JK, Kieffer CD, Killeen AA, Ptacin JL, Richmond CS, Roesch EB, Scherrer CW, Sherrill CB, Van Hout CV, Zanton SJ, Prudent JR.

Clin Chem. 2003 Mar;49(3):407-14.

30.

Functional evolution of the Ultrabithorax protein.

Grenier JK, Carroll SB.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):704-9.

31.

Hox genes in brachiopods and priapulids and protostome evolution.

de Rosa R, Grenier JK, Andreeva T, Cook CE, Adoutte A, Akam M, Carroll SB, Balavoine G.

Nature. 1999 Jun 24;399(6738):772-6.

PMID:
10391241
32.

Evolution of the entire arthropod Hox gene set predated the origin and radiation of the onychophoran/arthropod clade.

Grenier JK, Garber TL, Warren R, Whitington PM, Carroll S.

Curr Biol. 1997 Aug 1;7(8):547-53.

33.

The origin and evolution of animal appendages.

Panganiban G, Irvine SM, Lowe C, Roehl H, Corley LS, Sherbon B, Grenier JK, Fallon JF, Kimble J, Walker M, Wray GA, Swalla BJ, Martindale MQ, Carroll SB.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):5162-6.

34.

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