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Items: 42

1.

Activation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells.

Zegeye MM, Lindkvist M, Fälker K, Kumawat AK, Paramel G, Grenegård M, Sirsjö A, Ljungberg LU.

Cell Commun Signal. 2018 Sep 5;16(1):55. doi: 10.1186/s12964-018-0268-4.

2.

Increased plasma cathepsin S and trombospondin-1 in patients with acute ST segment elevation myocardial infarction.

Befekadu R, Christiansen K, Larsson A, Grenegård M.

Cardiol J. 2018 Apr 3. doi: 10.5603/CJ.a2018.0030. [Epub ahead of print]

3.

Fucoidan-Mimetic Glycopolymers as Tools for Studying Molecular and Cellular Responses in Human Blood Platelets.

Tengdelius M, Kardeby C, Fälker K, Griffith M, Påhlsson P, Konradsson P, Grenegård M.

Macromol Biosci. 2017 Feb;17(2). doi: 10.1002/mabi.201600257. Epub 2016 Sep 12.

PMID:
27616165
4.

Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release.

Donner L, Fälker K, Gremer L, Klinker S, Pagani G, Ljungberg LU, Lothmann K, Rizzi F, Schaller M, Gohlke H, Willbold D, Grenegard M, Elvers M.

Sci Signal. 2016 May 24;9(429):ra52. doi: 10.1126/scisignal.aaf6240.

PMID:
27221710
5.

Thrombin-induced lysosomal exocytosis in human platelets is dependent on secondary activation by ADP and regulated by endothelial-derived substances.

Södergren AL, Svensson Holm AC, Ramström S, Lindström EG, Grenegård M, Öllinger K.

Platelets. 2016;27(1):86-92. doi: 10.3109/09537104.2015.1042446. Epub 2015 May 13.

6.

The neutrophil serine protease PR3 induces shape change of platelets via the Rho/Rho kinase and Ca(2+) signaling pathways.

Peng X, Ramström S, Kurz T, Grenegård M, Segelmark M.

Thromb Res. 2014 Aug;134(2):418-25. doi: 10.1016/j.thromres.2014.06.001. Epub 2014 Jun 11.

7.

Thrombin-induced platelet activation via PAR4: pivotal role for exosite II.

Boknäs N, Faxälv L, Sanchez Centellas D, Wallstedt M, Ramström S, Grenegård M, Lindahl TL.

Thromb Haemost. 2014 Sep 2;112(3):558-65. doi: 10.1160/TH13-12-1013. Epub 2014 Jul 3.

8.

Synthesis and biological evaluation of fucoidan-mimetic glycopolymers through cyanoxyl-mediated free-radical polymerization.

Tengdelius M, Lee CJ, Grenegård M, Griffith M, Påhlsson P, Konradsson P.

Biomacromolecules. 2014 Jul 14;15(7):2359-68. doi: 10.1021/bm5002312. Epub 2014 Jun 10.

9.

The toll-like receptor 2/1 (TLR2/1) complex initiates human platelet activation via the src/Syk/LAT/PLCγ2 signalling cascade.

Fälker K, Klarström-Engström K, Bengtsson T, Lindahl TL, Grenegård M.

Cell Signal. 2014 Feb;26(2):279-86. doi: 10.1016/j.cellsig.2013.11.011. Epub 2013 Nov 12.

PMID:
24240055
10.

Differentiation of human dermal fibroblasts towards endothelial cells.

Junker JP, Lönnqvist S, Rakar J, Karlsson LK, Grenegård M, Kratz G.

Differentiation. 2013 Feb;85(3):67-77. doi: 10.1016/j.diff.2013.01.005. Epub 2013 May 3.

PMID:
23644553
11.

Inhibition of 12-lipoxygenase reduces platelet activation and prevents their mitogenic function.

Svensson Holm AC, Grenegård M, Ollinger K, Lindström EG.

Platelets. 2014;25(2):111-7. doi: 10.3109/09537104.2013.783688. Epub 2013 Mar 27.

PMID:
23534390
12.

A novel role for phospholipase D as an endogenous negative regulator of platelet sensitivity.

Elvers M, Grenegård M, Khoshjabinzadeh H, Münzer P, Borst O, Tian H, Di Paolo G, Lang F, Gawaz M, Lindahl TL, Fälker K.

Cell Signal. 2012 Sep;24(9):1743-52. doi: 10.1016/j.cellsig.2012.04.018. Epub 2012 May 3.

PMID:
22579635
13.

Hyaluronic acid influence on platelet-induced airway smooth muscle cell proliferation.

Svensson Holm AC, Bengtsson T, Grenegård M, Lindström EG.

Exp Cell Res. 2012 Mar 10;318(5):632-40. doi: 10.1016/j.yexcr.2011.12.011. Epub 2011 Dec 27.

14.

Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets.

Fälker K, Haglund L, Gunnarsson P, Nylander M, Lindahl TL, Grenegård M.

Biochem J. 2011 Jun 1;436(2):469-80. doi: 10.1042/BJ20101360.

PMID:
21391917
15.

Platelet membranes induce airway smooth muscle cell proliferation.

Svensson Holm AC, Bengtsson T, Grenegård M, Lindström EG.

Platelets. 2011;22(1):45-55. doi: 10.3109/09537104.2010.515696. Epub 2011 Jan 3.

PMID:
21194398
16.

Toll-like receptor 2 stimulation of platelets is mediated by purinergic P2X1-dependent Ca2+ mobilisation, cyclooxygenase and purinergic P2Y1 and P2Y12 receptor activation.

Kälvegren H, Skoglund C, Helldahl C, Lerm M, Grenegård M, Bengtsson T.

Thromb Haemost. 2010 Feb;103(2):398-407. doi: 10.1160/TH09-07-0442. Epub 2009 Dec 18.

PMID:
20024498
17.

alpha(1)-acid glycoprotein (AGP)-induced platelet shape change involves the Rho/Rho kinase signalling pathway.

Gunnarsson P, Levander L, Påhlsson P, Grenegård M.

Thromb Haemost. 2009 Oct;102(4):694-703. doi: 10.1160/TH09-03-0156.

PMID:
19806255
18.

Sialic acid residues play a pivotal role in alpha(1)-acid glycoprotein (AGP)-induced generation of reactive oxygen species in chemotactic peptide pre-activated neutrophil granulocytes.

Gunnarsson P, Fornander L, Påhlsson P, Grenegård M.

Inflamm Res. 2010 Feb;59(2):89-95. doi: 10.1007/s00011-009-0071-1. Epub 2009 Aug 11.

PMID:
19669698
19.

Human dermal fibroblasts: a potential cell source for endothelialization of vascular grafts.

Karlsson LK, Junker JP, Grenegård M, Kratz G.

Ann Vasc Surg. 2009 Sep-Oct;23(5):663-74. doi: 10.1016/j.avsg.2009.03.007. Epub 2009 Jul 3.

PMID:
19576728
20.

Effects of alpha1-acid glycoprotein fucosylation on its Ca2+ mobilizing capacity in neutrophils.

Levander L, Gunnarsson P, Grenegård M, Rydén I, Påhlsson P.

Scand J Immunol. 2009 May;69(5):412-20. doi: 10.1111/j.1365-3083.2009.02240.x. Epub 2009 Feb 26.

21.

Platelets stimulate airway smooth muscle cell proliferation through mechanisms involving 5-lipoxygenase and reactive oxygen species.

Svensson Holm AC, Bengtsson T, Grenegård M, Lindström EG.

Platelets. 2008 Nov;19(7):528-36. doi: 10.1080/09537100802320300.

PMID:
18979365
22.

The periodontal pathogen Porphyromonas gingivalis sensitises human blood platelets to epinephrine.

Nylander M, Lindahl TL, Bengtsson T, Grenegård M.

Platelets. 2008 Aug;19(5):352-8. doi: 10.1080/09537100802056102.

PMID:
18791941
23.

The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.

Grenegård M, Vretenbrant-Oberg K, Nylander M, Désilets S, Lindström EG, Larsson A, Ramström I, Ramström S, Lindahl TL.

J Biol Chem. 2008 Jul 4;283(27):18493-504. doi: 10.1074/jbc.M800358200. Epub 2008 May 14.

24.
25.

Platelet activation triggered by Chlamydia pneumoniae is antagonized by 12-lipoxygenase inhibitors but not cyclooxygenase inhibitors.

Kälvegren H, Andersson J, Grenegård M, Bengtsson T.

Eur J Pharmacol. 2007 Jul 2;566(1-3):20-7. Epub 2007 Mar 24.

PMID:
17459368
26.

Independent and additive stimulation of tendon repair by thrombin and platelets.

Virchenko O, Grenegård M, Aspenberg P.

Acta Orthop. 2006 Dec;77(6):960-6.

PMID:
17260208
27.

Dual actions of dephostatin on the nitric oxide/cGMP-signalling pathway in porcine iliac arteries.

Persson AA, Gunnarsson P, Lindström E, Grenegård M.

Eur J Pharmacol. 2005 Oct 3;521(1-3):124-32. Epub 2005 Sep 22.

PMID:
16182278
28.
29.

Nitric oxide inhibits gastric acid secretion by increasing intraparietal cell levels of cGMP in isolated human gastric glands.

Berg A, Redéen S, Grenegård M, Ericson AC, Sjöstrand SE.

Am J Physiol Gastrointest Liver Physiol. 2005 Dec;289(6):G1061-6. Epub 2005 Aug 11.

30.

Cross-talk between adenosine and the oxatriazole derivative GEA 3175 in platelets.

Asplund Persson A, Zalavary S, Lindström E, Whiss PA, Bengtsson T, Grenegård M.

Eur J Pharmacol. 2005 Jul 11;517(3):149-57.

PMID:
15963495
31.

Characterisation of GEA 3175 on human platelets; comparison with S-nitroso-N-acetyl-D,L-penicillamine.

Asplund Persson AK, Palmér L, Gunnarsson P, Grenegård M.

Eur J Pharmacol. 2004 Aug 2;496(1-3):1-9.

PMID:
15288569
32.

Leucocyte activation by collagen-stimulated platelets in whole blood.

Bengtsson T, Grenegård M.

Scand J Clin Lab Invest. 2002;62(6):451-61.

PMID:
12469900
33.

Synergistic activation of human platelets by lysophosphatidic acid and adrenaline.

Nilsson U, Svensson SP, Grenegård M.

Haematologica. 2002 Jul;87(7):730-9; discussion 739.

34.
35.

Platelets enhance neutrophil locomotion: evidence for a role of P-selectin.

Bengtsson T, Frydén A, Zalavary S, Whiss PA, Orselius K, Grenegård M.

Scand J Clin Lab Invest. 1999 Oct;59(6):439-49.

PMID:
10612555
36.
37.

Effects of the nitric oxide-donor, GEA 3175, on guinea-pig airways.

Johansson Rydberg IG, Andersson RG, Grenegård M.

Eur J Pharmacol. 1997 Jun 25;329(2-3):175-80.

PMID:
9226411
38.

Sulfatide-induced L-selectin activation generates intracellular oxygen radicals in human neutrophils: modulation by extracellular adenosine.

Bengtsson T, Grenegård M, Olsson A, Sjögren F, Stendahl O, Zalavary S.

Biochim Biophys Acta. 1996 Aug 28;1313(2):119-29.

39.

Synergistic inhibition of thrombin-induced platelet aggregation by the novel nitric oxide-donor GEA 3175 and adenosine.

Grenegård M, Gustafsson MC, Andersson RG, Bengtsson T.

Br J Pharmacol. 1996 Aug;118(8):2140-4.

40.
42.

Platelets amplify chemotactic peptide-induced changes in F-actin and calcium in human neutrophils.

Bengtsson T, Grenegård M.

Eur J Cell Biol. 1994 Apr;63(2):345-9. No abstract available.

PMID:
8082658

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