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Items: 14


High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis.

Mason DM, Weber CR, Parola C, Meng SM, Greiff V, Kelton WJ, Reddy ST.

Nucleic Acids Res. 2018 Aug 21;46(14):7436-7449. doi: 10.1093/nar/gky550.


Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires.

Miho E, Yermanos A, Weber CR, Berger CT, Reddy ST, Greiff V.

Front Immunol. 2018 Feb 21;9:224. doi: 10.3389/fimmu.2018.00224. eCollection 2018. Review.


Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim).

Yermanos A, Greiff V, Krautler NJ, Menzel U, Dounas A, Miho E, Oxenius A, Stadler T, Reddy ST.

Bioinformatics. 2017 Dec 15;33(24):3938-3946. doi: 10.1093/bioinformatics/btx533.


Learning the High-Dimensional Immunogenomic Features That Predict Public and Private Antibody Repertoires.

Greiff V, Weber CR, Palme J, Bodenhofer U, Miho E, Menzel U, Reddy ST.

J Immunol. 2017 Oct 15;199(8):2985-2997. doi: 10.4049/jimmunol.1700594. Epub 2017 Sep 18.


Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development.

Greiff V, Menzel U, Miho E, Weber C, Riedel R, Cook S, Valai A, Lopes T, Radbruch A, Winkler TH, Reddy ST.

Cell Rep. 2017 May 16;19(7):1467-1478. doi: 10.1016/j.celrep.2017.04.054.


Low immunoglobulin E flags two distinct types of immune dysregulation.

Elkuch M, Greiff V, Berger CT, Bouchenaki M, Daikeler T, Bircher A, Navarini AA, Heijnen I, Recher M.

Clin Exp Immunol. 2017 Mar;187(3):345-352. doi: 10.1111/cei.12885. Epub 2017 Jan 11.


Bioinformatic and Statistical Analysis of Adaptive Immune Repertoires.

Greiff V, Miho E, Menzel U, Reddy ST.

Trends Immunol. 2015 Nov;36(11):738-749. doi: 10.1016/ Epub 2015 Oct 25. Review.


A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status.

Greiff V, Bhat P, Cook SC, Menzel U, Kang W, Reddy ST.

Genome Med. 2015 May 28;7(1):49. doi: 10.1186/s13073-015-0169-8. eCollection 2015.


Risk factors for pneumocystis pneumonia in giant cell arteritis: a single-centre cohort study.

Berger CT, Greiff V, John S, Koenig KF, Bigler MB, Recher M, Hess C, Daikeler T.

Clin Exp Rheumatol. 2015 Mar-Apr;33(2 Suppl 89):S-122-5. Epub 2015 May 26.


Influenza vaccine response profiles are affected by vaccine preparation and preexisting immunity, but not HIV infection.

Berger CT, Greiff V, Mehling M, Fritz S, Meier MA, Hoenger G, Conen A, Recher M, Battegay M, Reddy ST, Hess C.

Hum Vaccin Immunother. 2015;11(2):391-6. doi: 10.1080/21645515.2015.1008930.


Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice.

Greiff V, Menzel U, Haessler U, Cook SC, Friedensohn S, Khan TA, Pogson M, Hellmann I, Reddy ST.

BMC Immunol. 2014 Oct 16;15:40. doi: 10.1186/s12865-014-0040-5.


Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing.

Menzel U, Greiff V, Khan TA, Haessler U, Hellmann I, Friedensohn S, Cook SC, Pogson M, Reddy ST.

PLoS One. 2014 May 8;9(5):e96727. doi: 10.1371/journal.pone.0096727. eCollection 2014.


A minimal model of peptide binding predicts ensemble properties of serum antibodies.

Greiff V, Redestig H, Lück J, Bruni N, Valai A, Hartmann S, Rausch S, Schuchhardt J, Or-Guil M.

BMC Genomics. 2012 Feb 21;13:79. doi: 10.1186/1471-2164-13-79.


Sexuality in older women.

Mooradian AD, Greiff V.

Arch Intern Med. 1990 May;150(5):1033-8.


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