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Items: 1 to 50 of 100

1.

Effects of phosphate binders on the gastrointestinal absorption of arsenate and of an SGLT2 inhibitor drug on the urinary excretion of arsenite in mice.

Poór M, Németi B, Gregus Z.

Environ Toxicol Pharmacol. 2017 Jan;49:179-187. doi: 10.1016/j.etap.2017.01.002. Epub 2017 Jan 3.

PMID:
28068585
2.

Reduction of the Pentavalent Arsenical Dimethylarsinic Acid and the GSTO1 Substrate S-(4-Nitrophenacyl)glutathione by Rat Liver Cytosol: Analyzing the Role of GSTO1 in Arsenic Reduction.

Németi B, Poór M, Gregus Z.

Chem Res Toxicol. 2015 Nov 16;28(11):2199-209. doi: 10.1021/acs.chemrestox.5b00368. Epub 2015 Nov 3.

PMID:
26496421
3.

A high-performance liquid chromatography-based assay of glutathione transferase omega 1 supported by glutathione or non-physiological reductants.

Németi B, Poór M, Gregus Z.

Anal Biochem. 2015 Jan 15;469:12-8. doi: 10.1016/j.ab.2014.09.019. Epub 2014 Oct 2.

PMID:
25283130
4.

Reduction of dimethylarsinic acid to the highly toxic dimethylarsinous acid by rats and rat liver cytosol.

Németi B, Gregus Z.

Chem Res Toxicol. 2013 Mar 18;26(3):432-43. doi: 10.1021/tx300505v. Epub 2013 Mar 4.

PMID:
23414340
5.

Glutathione synthetase promotes the reduction of arsenate via arsenolysis of glutathione.

Németi B, Anderson ME, Gregus Z.

Biochimie. 2012 Jun;94(6):1327-33. doi: 10.1016/j.biochi.2012.02.033. Epub 2012 Mar 8.

PMID:
22426003
6.

The mechanism of the polynucleotide phosphorylase-catalyzed arsenolysis of ADP.

Németi B, Regonesi ME, Tortora P, Gregus Z.

Biochimie. 2011 Mar;93(3):624-7. doi: 10.1016/j.biochi.2010.11.013. Epub 2010 Dec 3.

PMID:
21130834
7.

Preface: 2nd International Congress, As 2008: arsenic from nature to humans (Valencia, Spain, May 21-23).

Styblo M, Gregus Z, Devesa V, Vélez D.

Environ Res. 2010 Jul;110(5):411-2. doi: 10.1016/j.envres.2010.04.003. Epub 2010 May 11. No abstract available.

PMID:
20462574
8.

Polynucleotide phosphorylase and mitochondrial ATP synthase mediate reduction of arsenate to the more toxic arsenite by forming arsenylated analogues of ADP and ATP.

Németi B, Regonesi ME, Tortora P, Gregus Z.

Toxicol Sci. 2010 Oct;117(2):270-81. doi: 10.1093/toxsci/kfq141. Epub 2010 May 10.

PMID:
20457661
9.

Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.

Gregus Z, Roos G, Geerlings P, Németi B.

Toxicol Sci. 2009 Aug;110(2):282-92. doi: 10.1093/toxsci/kfp113. Epub 2009 May 28.

PMID:
19478237
10.

Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: I. The role of arsenolysis.

Németi B, Gregus Z.

Toxicol Sci. 2009 Aug;110(2):270-81. doi: 10.1093/toxsci/kfp112. Epub 2009 May 27.

PMID:
19474219
11.

Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.

Németi B, Gregus Z.

Toxicol Appl Pharmacol. 2009 Sep 1;239(2):154-61. doi: 10.1016/j.taap.2009.02.011. Epub 2009 Feb 25.

PMID:
19248796
12.

Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis.

Németi B, Gregus Z.

Toxicol Sci. 2007 Nov;100(1):36-43. Epub 2007 Aug 9.

PMID:
17693425
13.
14.
16.
17.
18.
19.

Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase.

Nemeti B, Csanaky I, Gregus Z.

Toxicol Sci. 2003 Jul;74(1):22-31. Epub 2003 May 2.

PMID:
12730608
20.

Effect of selenite on the disposition of arsenate and arsenite in rats.

Csanaky I, Gregus Z.

Toxicology. 2003 Apr 15;186(1-2):33-50.

PMID:
12604169
21.
22.

Purine nucleoside phosphorylase as a cytosolic arsenate reductase.

Gregus Z, Németi B.

Toxicol Sci. 2002 Nov;70(1):13-9.

PMID:
12388830
23.

Reduction of arsenate to arsenite in hepatic cytosol.

Németi B, Gregus Z.

Toxicol Sci. 2002 Nov;70(1):4-12.

PMID:
12388829
24.

Mitochondria work as reactors in reducing arsenate to arsenite.

Németi B, Gregus Z.

Toxicol Appl Pharmacol. 2002 Aug 1;182(3):208-18.

PMID:
12183100
25.

Species variations in the biliary and urinary excretion of arsenate, arsenite and their metabolites.

Csanaky I, Gregus Z.

Comp Biochem Physiol C Toxicol Pharmacol. 2002 Mar;131(3):355-65.

PMID:
11912060
26.
27.

Effects of methylmercury and organic acid mercurials on the disposition of exogenous selenium in rats.

Gregus Z, Gyurasics A, Csanaky I, Pintér Z.

Toxicol Appl Pharmacol. 2001 Jul 15;174(2):177-87.

PMID:
11446833
28.

Role of glutathione in the biliary excretion of the arsenical drugs trimelarsan and melarsoprol.

Gregus Z, Gyurasics A.

Biochem Pharmacol. 2000 Jun 1;59(11):1375-85.

PMID:
10751546
29.

Effects of arsenic-, platinum-, and gold-containing drugs on the disposition of exogenous selenium in rats.

Gregus Z, Gyurasics A, Csanaky I.

Toxicol Sci. 2000 Sep;57(1):22-31.

PMID:
10966508
30.
31.

Effect of chlorophenoxyacetic acid herbicides on glycine conjugation of benzoic acid.

Gregus Z, Halászi E, Klaassen CD.

Xenobiotica. 1999 Jun;29(6):547-59.

PMID:
10426554
32.

Enhancement of selenium excretion in bile by sulfobromophthalein: elucidation of the mechanism.

Gregus Z, Perjési P, Gyurasics A.

Biochem Pharmacol. 1998 Nov 15;56(10):1391-402.

PMID:
9825739
33.

Role of glutathione and methylation in the biliary excretion of selenium. The paradoxical effect of sulfobromophthalein.

Gyurasics A, Perjési P, Gregus Z.

Biochem Pharmacol. 1998 Nov 15;56(10):1381-9.

PMID:
9825738
34.

Effects of fibrates on the glycine conjugation of benzoic acid in rats.

Gregus Z, Fekete T, Halászi E, Gyurasics A, Klaassen CD.

Drug Metab Dispos. 1998 Nov;26(11):1082-8.

PMID:
9806950
35.

[Human drug metabolizing enzymes. II. Conjugation enzymes].

Vereczkey L, Jemnitz K, Gregus Z.

Acta Pharm Hung. 1998 Sep;68(5):284-8. Review. Hungarian.

PMID:
9805814
36.

Interactions between selenium and group Va-metalloids (arsenic, antimony and bismuth) in the biliary excretion.

Gregus Z, Gyurasics A, Koszorús L.

Environ Toxicol Pharmacol. 1998 Mar;5(2):89-99.

PMID:
21781854
37.

Does hepatic ATP depletion impair glycine conjugation in vivo?

Gregus Z, Fekete T, Halászi E, Klaassen CD.

Drug Metab Dispos. 1996 Dec;24(12):1347-54.

PMID:
8971141
38.

Lipoic acid impairs glycine conjugation of benzoic acid and renal excretion of benzoylglycine.

Gregus Z, Fekete T, Halászi E, Klaassen CD.

Drug Metab Dispos. 1996 Jun;24(6):682-8.

PMID:
8781786
39.

Simple method for analysis of diquat in biological fluids and tissues by high-performance liquid chromatography.

Madhu C, Gregus Z, Klaassen CD.

J Chromatogr B Biomed Appl. 1995 Dec 15;674(2):193-6.

PMID:
8788148
40.

Molybdate depletes hepatic 3-phosphoadenosine 5-phosphosulfate and impairs the sulfation of acetaminophen in rats.

Oguro T, Gregus Z, Madhu C, Liu L, Klaassen CD.

J Pharmacol Exp Ther. 1994 Sep;270(3):1145-51.

PMID:
7932164
41.
42.

Nutritionally and chemically induced impairment of sulfate activation and sulfation of xenobiotics in vivo.

Gregus Z, Oguro T, Klaassen CD.

Chem Biol Interact. 1994 Jun;92(1-3):169-77.

PMID:
8033252
43.

Effect of valproic acid on glycine conjugation of benzoic acid.

Gregus Z, Fekete T, Varga F, Klaassen CD.

J Pharmacol Exp Ther. 1993 Dec;267(3):1068-75.

PMID:
8263766
44.

Dependence of glycine conjugation on availability of glycine: role of the glycine cleavage system.

Gregus Z, Fekete T, Varga F, Klaassen CD.

Xenobiotica. 1993 Feb;23(2):141-53.

PMID:
8498078
46.

Increased biliary excretion of glutathione is generated by the glutathione-dependent hepatobiliary transport of antimony and bismuth.

Gyurasics A, Koszorús L, Varga F, Gregus Z.

Biochem Pharmacol. 1992 Oct 6;44(7):1275-81.

PMID:
1417951
47.
48.

Effect of lipoic acid on biliary excretion of glutathione and metals.

Gregus Z, Stein AF, Varga F, Klaassen CD.

Toxicol Appl Pharmacol. 1992 May;114(1):88-96.

PMID:
1585376
49.

Homeostasis of sulfate and 3'-phosphoadenosine 5'-phosphosulfate in rats with deficient dietary intake of sulfur.

Rozman P, Kim HJ, Madhu C, Gregus Z, Klaassen CD.

Drug Metab Dispos. 1992 May-Jun;20(3):374-8.

PMID:
1355710
50.

Availability of glycine and coenzyme A limits glycine conjugation in vivo.

Gregus Z, Fekete T, Varga F, Klaassen CD.

Drug Metab Dispos. 1992 Mar-Apr;20(2):234-40.

PMID:
1352215

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