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Items: 1 to 50 of 72

1.

An update on the genetics of ocular coloboma.

ALSomiry AS, Gregory-Evans CY, Gregory-Evans K.

Hum Genet. 2019 Sep;138(8-9):865-880. doi: 10.1007/s00439-019-02019-3. Epub 2019 May 9. Review.

PMID:
31073883
2.

Prospects and modalities for the treatment of genetic ocular anomalies.

Gregory-Evans CY, Wang X, Gregory-Evans K.

Hum Genet. 2019 Sep;138(8-9):1019-1026. doi: 10.1007/s00439-018-01968-5. Epub 2019 Jan 2. Review.

PMID:
30603775
3.

The olfactory mucosa: a potential source of stem cells for hearing regeneration.

Young E, Westerberg B, Yanai A, Gregory-Evans K.

Regen Med. 2018 Jul 1;13(5):581-593. doi: 10.2217/rme-2018-0009. Epub 2018 Aug 16. Review.

PMID:
30113240
4.

Cell Death Pathways in Mutant Rhodopsin Rat Models Identifies Genotype-Specific Targets Controlling Retinal Degeneration.

Viringipurampeer IA, Gregory-Evans CY, Metcalfe AL, Bashar E, Moritz OL, Gregory-Evans K.

Mol Neurobiol. 2019 Mar;56(3):1637-1652. doi: 10.1007/s12035-018-1192-8. Epub 2018 Jun 18.

PMID:
29911255
5.

Anolis carolinensis as a model to understand the molecular and cellular basis of foveal development.

Sannan NS, Shan X, Gregory-Evans K, Kusumi K, Gregory-Evans CY.

Exp Eye Res. 2018 Aug;173:138-147. doi: 10.1016/j.exer.2018.05.012. Epub 2018 May 15.

PMID:
29775563
6.

Correlation of novel PAX6 gene abnormalities in aniridia and clinical presentation.

Sannan NS, Gregory-Evans CY, Lyons CJ, Lehman AM, Langlois S, Warner SJ, Zakrzewski H, Gregory-Evans K.

Can J Ophthalmol. 2017 Dec;52(6):570-577. doi: 10.1016/j.jcjo.2017.04.006. Epub 2017 Jul 6.

PMID:
29217025
7.

Efficacy of Postnatal In Vivo Nonsense Suppression Therapy in a Pax6 Mouse Model of Aniridia.

Wang X, Gregory-Evans K, Wasan KM, Sivak O, Shan X, Gregory-Evans CY.

Mol Ther Nucleic Acids. 2017 Jun 16;7:417-428. doi: 10.1016/j.omtn.2017.05.002. Epub 2017 May 8.

8.

An ex vivo gene therapy approach in X-linked retinoschisis.

Bashar AE, Metcalfe AL, Viringipurampeer IA, Yanai A, Gregory-Evans CY, Gregory-Evans K.

Mol Vis. 2016 Jun 24;22:718-33. eCollection 2016.

9.

Anti-ageing glycoprotein promotes long-term survival of transplanted neurosensory precursor cells.

Yanai A, Viringipurampeer IA, Bashar E, Gregory-Evans K.

J Tissue Eng Regen Med. 2017 Sep;11(9):2658-2662. doi: 10.1002/term.2176. Epub 2016 May 27.

PMID:
27229654
10.

NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration.

Viringipurampeer IA, Metcalfe AL, Bashar AE, Sivak O, Yanai A, Mohammadi Z, Moritz OL, Gregory-Evans CY, Gregory-Evans K.

Hum Mol Genet. 2016 Apr 15;25(8):1501-16. doi: 10.1093/hmg/ddw029. Epub 2016 Feb 7.

11.

Bimodal in vivo imaging provides early assessment of stem-cell-based photoreceptor engraftment.

Laver CR, Metcalfe AL, Szczygiel L, Yanai A, Sarunic MV, Gregory-Evans K.

Eye (Lond). 2015 May;29(5):681-90. doi: 10.1038/eye.2015.24. Epub 2015 Mar 13.

12.

Enhanced functional integration of human photoreceptor precursors into human and rodent retina in an ex vivo retinal explant model system.

Yanai A, Laver CR, Gregory-Evans CY, Liu RR, Gregory-Evans K.

Tissue Eng Part A. 2015 Jun;21(11-12):1763-71. doi: 10.1089/ten.TEA.2014.0669. Epub 2015 Mar 24.

13.

Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish.

Viringipurampeer IA, Shan X, Gregory-Evans K, Zhang JP, Mohammadi Z, Gregory-Evans CY.

Cell Death Differ. 2014 May;21(5):665-75. doi: 10.1038/cdd.2013.191. Epub 2014 Jan 10.

14.

Postnatal manipulation of Pax6 dosage reverses congenital tissue malformation defects.

Gregory-Evans CY, Wang X, Wasan KM, Zhao J, Metcalfe AL, Gregory-Evans K.

J Clin Invest. 2014 Jan;124(1):111-6. doi: 10.1172/JCI70462. Epub 2013 Dec 20.

15.

Efficient Production of Photoreceptor Precursor Cells from Human Embryonic Stem Cells.

Yanai A, Laver C, Joe AW, Gregory-Evans K.

Methods Mol Biol. 2016;1307:357-69. doi: 10.1007/7651_2013_57.

PMID:
24301073
16.

RD3 gene delivery restores guanylate cyclase localization and rescues photoreceptors in the Rd3 mouse model of Leber congenital amaurosis 12.

Molday LL, Djajadi H, Yan P, Szczygiel L, Boye SL, Chiodo VA, Gregory-Evans K, Sarunic MV, Hauswirth WW, Molday RS.

Hum Mol Genet. 2013 Oct 1;22(19):3894-905. doi: 10.1093/hmg/ddt244. Epub 2013 Jun 4.

17.

Targeting inflammation in emerging therapies for genetic retinal disease.

Viringipurampeer IA, Bashar AE, Gregory-Evans CY, Moritz OL, Gregory-Evans K.

Int J Inflam. 2013;2013:581751. doi: 10.1155/2013/581751. Epub 2013 Feb 21.

18.

Differentiation of human embryonic stem cells using size-controlled embryoid bodies and negative cell selection in the production of photoreceptor precursor cells.

Yanai A, Laver CR, Joe AW, Viringipurampeer IA, Wang X, Gregory-Evans CY, Gregory-Evans K.

Tissue Eng Part C Methods. 2013 Oct;19(10):755-64. doi: 10.1089/ten.TEC.2012.0524. Epub 2013 Mar 15.

19.

Influence of Iron Oxide Nanoparticles on Innate and Genetically Modified Secretion Profiles of Mesenchymal Stem Cells.

Bashar AE, Metcalfe A, Yanai A, Laver C, Häfeli UO, Gregory-Evans CY, Moritz OL, Matsubara JA, Gregory-Evans K.

IEEE Trans Magn. 2013 Jan 1;49(1):389-393.

20.

Use of magnetism to enhance cell transplantation success in regenerative medicine.

Gregory-Evans K, Bashar AE, Laver C.

Regen Med. 2013 Jan;8(1):1-3. doi: 10.2217/rme.12.104. No abstract available.

21.

Gene networks: dissecting pathways in retinal development and disease.

Gregory-Evans CY, Wallace VA, Gregory-Evans K.

Prog Retin Eye Res. 2013 Mar;33:40-66. doi: 10.1016/j.preteyeres.2012.10.003. Epub 2012 Nov 2. Review.

PMID:
23128416
22.

Ex vivo gene therapy and vision.

Gregory-Evans K, Bashar AM, Tan M.

Curr Gene Ther. 2012 Apr 1;12(2):103-15. Review.

PMID:
22424554
23.

Focused magnetic stem cell targeting to the retina using superparamagnetic iron oxide nanoparticles.

Yanai A, Häfeli UO, Metcalfe AL, Soema P, Addo L, Gregory-Evans CY, Po K, Shan X, Moritz OL, Gregory-Evans K.

Cell Transplant. 2012;21(6):1137-48. doi: 10.3727/096368911X627435. Epub 2012 Mar 8.

PMID:
22405427
24.

Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development.

Viringipurampeer IA, Ferreira T, DeMaria S, Yoon JJ, Shan X, Moosajee M, Gregory-Evans K, Ngai J, Gregory-Evans CY.

Hum Mol Genet. 2012 May 15;21(10):2357-69. doi: 10.1093/hmg/dds056. Epub 2012 Feb 21.

25.

Retina restored and brain abnormalities ameliorated by single-copy knock-in of human NR2E1 in null mice.

Schmouth JF, Banks KG, Mathelier A, Gregory-Evans CY, Castellarin M, Holt RA, Gregory-Evans K, Wasserman WW, Simpson EM.

Mol Cell Biol. 2012 Apr;32(7):1296-311. doi: 10.1128/MCB.06016-11. Epub 2012 Jan 30.

26.

Foxf2: a novel locus for anterior segment dysgenesis adjacent to the Foxc1 gene.

McKeone R, Vieira H, Gregory-Evans K, Gregory-Evans CY, Denny P.

PLoS One. 2011;6(10):e25489. doi: 10.1371/journal.pone.0025489. Epub 2011 Oct 13.

27.

Non-invasive anterior segment and posterior segment optical coherence tomography and phenotypic characterization of aniridia.

Gregory-Evans K, Cheong-Leen R, George SM, Xie J, Moosajee M, Colapinto P, Gregory-Evans CY.

Can J Ophthalmol. 2011 Aug;46(4):337-44. doi: 10.1016/j.jcjo.2011.06.011. Epub 2011 Jul 7.

PMID:
21816254
28.

Pharmacological enhancement of ex vivo gene therapy neuroprotection in a rodent model of retinal degeneration.

Gregory-Evans K, Po K, Chang F, Gregory-Evans CY.

Ophthalmic Res. 2012;47(1):32-8. doi: 10.1159/000325730. Epub 2011 Jun 21.

PMID:
21691141
29.

Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma.

Gregory-Evans CY, Moosajee M, Shan X, Gregory-Evans K.

Mol Vis. 2011;17:1473-84. Epub 2011 Jun 4.

30.

Mesenchymal stem cells and potential applications in treating ocular disease.

Joe AW, Gregory-Evans K.

Curr Eye Res. 2010 Nov;35(11):941-52. doi: 10.3109/02713683.2010.516466. Review.

PMID:
20958182
31.

Successful Treatment of Subretinal Neovascularization with Intravitreal Ranibizumab in a Child with Optic Nerve Head Drusen.

Gregory-Evans K, Rai P, Patterson J.

J Pediatr Ophthalmol Strabismus. 2009 Aug 21. doi: 10.3928/01913913-20090818-03. Epub 2009 Aug 21.

PMID:
20842978
32.
33.

Translational bypass of nonsense mutations in zebrafish rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease.

Moosajee M, Gregory-Evans K, Ellis CD, Seabra MC, Gregory-Evans CY.

Hum Mol Genet. 2008 Dec 15;17(24):3987-4000. doi: 10.1093/hmg/ddn302. Epub 2008 Sep 22.

PMID:
18809619
34.

Systemic aminoglycoside treatment in rodent models of retinitis pigmentosa.

Guerin K, Gregory-Evans CY, Hodges MD, Moosajee M, Mackay DS, Gregory-Evans K, Flannery JG.

Exp Eye Res. 2008 Sep;87(3):197-207. doi: 10.1016/j.exer.2008.05.016. Epub 2008 Jun 3.

PMID:
18644591
35.

Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina.

Zaidi FH, Hull JT, Peirson SN, Wulff K, Aeschbach D, Gooley JJ, Brainard GC, Gregory-Evans K, Rizzo JF 3rd, Czeisler CA, Foster RG, Moseley MJ, Lockley SW.

Curr Biol. 2007 Dec 18;17(24):2122-8.

36.

SNP genome scanning localizes oto-dental syndrome to chromosome 11q13 and microdeletions at this locus implicate FGF3 in dental and inner-ear disease and FADD in ocular coloboma.

Gregory-Evans CY, Moosajee M, Hodges MD, Mackay DS, Game L, Vargesson N, Bloch-Zupan A, Rüschendorf F, Santos-Pinto L, Wackens G, Gregory-Evans K.

Hum Mol Genet. 2007 Oct 15;16(20):2482-93. Epub 2007 Jul 25.

PMID:
17656375
37.

Subretinal membranes are associated with abnormal degrees of pupil "evasion": an index of clinical macular dysfunction.

Zaidi FH, Bremner FD, Gregory-Evans K, Cocker KD, Moseley MJ.

Br J Ophthalmol. 2006 Sep;90(9):1115-8.

38.

Maculopathy due to the R345W substitution in fibulin-3: distinct clinical features, disease variability, and extent of retinal dysfunction.

Michaelides M, Jenkins SA, Brantley MA Jr, Andrews RM, Waseem N, Luong V, Gregory-Evans K, Bhattacharya SS, Fitzke FW, Webster AR.

Invest Ophthalmol Vis Sci. 2006 Jul;47(7):3085-97.

PMID:
16799055
39.

Familial Bell's palsy in females: a phenotype with a predilection for eyelids and lacrimal gland.

Zaidi FH, Gregory-Evans K, Acheson JF, Ferguson V.

Orbit. 2005 Jun;24(2):121-4.

PMID:
16191801
40.

Replacing the Amsler grid.

Zaidi FH, Gregory-Evans K.

Ophthalmology. 2005 Feb;112(2):357; author reply 357. No abstract available.

PMID:
15691577
41.

Ocular coloboma: a reassessment in the age of molecular neuroscience.

Gregory-Evans CY, Williams MJ, Halford S, Gregory-Evans K.

J Med Genet. 2004 Dec;41(12):881-91. Review.

42.

Ocular coloboma and high myopia with Hirschsprung disease associated with a novel ZFHX1B missense mutation and trisomy 21.

Gregory-Evans CY, Vieira H, Dalton R, Adams GG, Salt A, Gregory-Evans K.

Am J Med Genet A. 2004 Nov 15;131(1):86-90.

PMID:
15384097
43.

Desferrioxamine related maculopathy: a case report.

Arora A, Wren S, Gregory Evans K.

Am J Hematol. 2004 Aug;76(4):386-8.

44.

Optical coherence tomography findings in benign concentric annular dystrophy.

Burton BJ, Holder GE, Duguid G, Gregory-Evans K.

Eye (Lond). 2005 Jun;19(6):699-701. Review. No abstract available.

PMID:
15184947
45.

The Amsler chart is of doubtful value in retinal screening for early laser therapy of subretinal membranes. The West London Survey.

Zaidi FH, Cheong-Leen R, Gair EJ, Weir R, Sharkawi E, Lee N, Gregory-Evans K.

Eye (Lond). 2004 May;18(5):503-8.

PMID:
15131682
46.

Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.

Toomes C, Bottomley HM, Jackson RM, Towns KV, Scott S, Mackey DA, Craig JE, Jiang L, Yang Z, Trembath R, Woodruff G, Gregory-Evans CY, Gregory-Evans K, Parker MJ, Black GC, Downey LM, Zhang K, Inglehearn CF.

Am J Hum Genet. 2004 Apr;74(4):721-30. Epub 2004 Mar 11.

47.

Criteria for improving visual acuity in ischaemic branch retinal vein occlusion using argon laser.

Zaidi FH, Gair EJ, Gregory-Evans K.

Eye (Lond). 2004 Mar;18(3):316-8.

PMID:
15004585
48.

Mouse genetic corneal disease resulting from transgenic insertional mutagenesis.

Ramalho JS, Gregory-Evans K, Huxley C, Seabra MC.

Br J Ophthalmol. 2004 Mar;88(3):428-32.

49.

Transcriptional regulation and expression of the dominant drusen gene FBLN3 (EFEMP1) in mammalian retina.

Blackburn J, Tarttelin EE, Gregory-Evans CY, Moosajee M, Gregory-Evans K.

Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4613-21.

PMID:
14578376
50.

Gene structure and tissue expression of human selenoprotein W, SEPW1, and identification of a retroprocessed pseudogene, SEPW1P.

Bellingham J, Gregory-Evans K, Fox MF, Gregory-Evans CY.

Biochim Biophys Acta. 2003 Jun 19;1627(2-3):140-6.

PMID:
12818432

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