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Items: 1 to 50 of 63

1.

MicroRNA-143-3p targets pyruvate carboxylase expression and controls proliferation and migration of MDA-MB-231 cells.

Pinweha P, Phillips CA, Gregory PA, Li X, Chuayboonya P, Mongkolsiri P, Goodall GJ, Jitrapakdee S.

Arch Biochem Biophys. 2019 Nov 4;677:108169. doi: 10.1016/j.abb.2019.108169. [Epub ahead of print]

PMID:
31697914
2.

The miR-200-Quaking axis functions in tumour angiogenesis.

Gregory PA.

Oncogene. 2019 Oct;38(41):6767-6769. doi: 10.1038/s41388-019-0916-1. Epub 2019 Aug 12. No abstract available.

PMID:
31406253
3.

Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA).

Pillman KA, Scheer KG, Hackett-Jones E, Saunders K, Bert AG, Toubia J, Whitfield HJ, Sapkota S, Sourdin L, Pham H, Le TD, Cursons J, Davis MJ, Gregory PA, Goodall GJ, Bracken CP.

Nucleic Acids Res. 2019 Sep 19;47(16):8606-8619. doi: 10.1093/nar/gkz664.

PMID:
31372646
4.

Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT.

Cursons J, Pillman KA, Scheer KG, Gregory PA, Foroutan M, Hediyeh-Zadeh S, Toubia J, Crampin EJ, Goodall GJ, Bracken CP, Davis MJ.

Cell Syst. 2018 Jul 25;7(1):77-91.e7. doi: 10.1016/j.cels.2018.05.019. Epub 2018 Jul 11.

5.

miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking.

Pillman KA, Phillips CA, Roslan S, Toubia J, Dredge BK, Bert AG, Lumb R, Neumann DP, Li X, Conn SJ, Liu D, Bracken CP, Lawrence DM, Stylianou N, Schreiber AW, Tilley WD, Hollier BG, Khew-Goodall Y, Selth LA, Goodall GJ, Gregory PA.

EMBO J. 2018 Jul 2;37(13). pii: e99016. doi: 10.15252/embj.201899016. Epub 2018 Jun 5.

6.

The role of disengagement in the psychology of competence drift.

Austin Z, Gregory PAM.

Res Social Adm Pharm. 2019 Jan;15(1):45-52. doi: 10.1016/j.sapharm.2018.02.011. Epub 2018 Feb 27.

PMID:
29502903
7.

Meeting Report: The 8th Barossa Meeting-Cell Signaling in Cancer Medicine in the Barossa Valley, Australia.

Gomez GA, Woodcock JM, Tergaonkar V, Gregory PA.

Cell Death Dis. 2018 Feb 15;9(3):284. doi: 10.1038/s41419-018-0285-7. No abstract available.

8.

What does it take to change practice? Perspectives of pharmacists in Ontario.

Gregory PAM, Teixeira B, Austin Z.

Can Pharm J (Ott). 2017 Dec 1;151(1):43-50. doi: 10.1177/1715163517742677. eCollection 2018 Jan-Feb.

9.

Regulation of splicing and circularisation of RNA in epithelial mesenchymal plasticity.

Neumann DP, Goodall GJ, Gregory PA.

Semin Cell Dev Biol. 2018 Mar;75:50-60. doi: 10.1016/j.semcdb.2017.08.008. Epub 2017 Aug 5. Review.

PMID:
28789987
10.

How are pharmacists in Ontario adapting to practice change? Results of a qualitative analysis using Kotter's change management model.

Teixeira B, Gregory PAM, Austin Z.

Can Pharm J (Ott). 2017 Apr 6;150(3):198-205. doi: 10.1177/1715163517701470. eCollection 2017 May-Jun.

11.

Conflict in community pharmacy practice: The experience of pharmacists, technicians and assistants.

Gregory PA, Austin Z.

Can Pharm J (Ott). 2016 Dec 8;150(1):32-41. doi: 10.1177/1715163516679426. eCollection 2017 Jan-Feb.

12.

Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality.

Tse BWC, Volpert M, Ratther E, Stylianou N, Nouri M, McGowan K, Lehman ML, McPherson SJ, Roshan-Moniri M, Butler MS, Caradec J, Gregory-Evans CY, McGovern J, Das R, Takhar M, Erho N, Alshalafa M, Davicioni E, Schaeffer EM, Jenkins RB, Ross AE, Karnes RJ, Den RB, Fazli L, Gregory PA, Gleave ME, Williams ED, Rennie PS, Buttyan R, Gunter JH, Selth LA, Russell PJ, Nelson CC, Hollier BG.

Oncogene. 2017 Jun 15;36(24):3417-3427. doi: 10.1038/onc.2016.482. Epub 2017 Jan 16.

13.

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.

Das R, Gregory PA, Fernandes RC, Denis I, Wang Q, Townley SL, Zhao SG, Hanson AR, Pickering MA, Armstrong HK, Lokman NA, Ebrahimie E, Davicioni E, Jenkins RB, Karnes RJ, Ross AE, Den RB, Klein EA, Chi KN, Ramshaw HS, Williams ED, Zoubeidi A, Goodall GJ, Feng FY, Butler LM, Tilley WD, Selth LA.

Cancer Res. 2017 Feb 15;77(4):1021-1034. doi: 10.1158/0008-5472.CAN-16-2529. Epub 2016 Dec 23.

14.

Trust in interprofessional collaboration: Perspectives of pharmacists and physicians.

Gregory PA, Austin Z.

Can Pharm J (Ott). 2016 Jul;149(4):236-45. doi: 10.1177/1715163516647749. Epub 2016 May 16.

15.

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

Selth LA, Das R, Townley SL, Coutinho I, Hanson AR, Centenera MM, Stylianou N, Sweeney K, Soekmadji C, Jovanovic L, Nelson CC, Zoubeidi A, Butler LM, Goodall GJ, Hollier BG, Gregory PA, Tilley WD.

Oncogene. 2017 Jan 5;36(1):24-34. doi: 10.1038/onc.2016.185. Epub 2016 Jun 6.

PMID:
27270433
16.

How do community pharmacists make decisions? Results of an exploratory qualitative study in Ontario.

Gregory PA, Whyte B, Austin Z.

Can Pharm J (Ott). 2016 Mar;149(2):90-8. doi: 10.1177/1715163515625656. Epub 2016 Feb 11.

17.

The RNA binding protein quaking regulates formation of circRNAs.

Conn SJ, Pillman KA, Toubia J, Conn VM, Salmanidis M, Phillips CA, Roslan S, Schreiber AW, Gregory PA, Goodall GJ.

Cell. 2015 Mar 12;160(6):1125-34. doi: 10.1016/j.cell.2015.02.014.

18.

Epithelial plasticity in prostate cancer: principles and clinical perspectives.

Das R, Gregory PA, Hollier BG, Tilley WD, Selth LA.

Trends Mol Med. 2014 Nov;20(11):643-51. doi: 10.1016/j.molmed.2014.09.004. Epub 2014 Sep 25. Review.

PMID:
25262538
19.

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion.

Bracken CP, Li X, Wright JA, Lawrence DM, Pillman KA, Salmanidis M, Anderson MA, Dredge BK, Gregory PA, Tsykin A, Neilsen C, Thomson DW, Bert AG, Leerberg JM, Yap AS, Jensen KB, Khew-Goodall Y, Goodall GJ.

EMBO J. 2014 Sep 17;33(18):2040-56. doi: 10.15252/embj.201488641. Epub 2014 Jul 28.

20.

Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells.

Zafar A, Wu F, Hardy K, Li J, Tu WJ, McCuaig R, Harris J, Khanna KK, Attema J, Gregory PA, Goodall GJ, Harrington K, Dahlstrom JE, Boulding T, Madden R, Tan A, Milburn PJ, Rao S.

Mol Cell Biol. 2014 Aug;34(16):2961-80. doi: 10.1128/MCB.01693-13. Epub 2014 Jun 2.

21.

Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition.

Kolesnikoff N, Attema JL, Roslan S, Bert AG, Schwarz QP, Gregory PA, Goodall GJ.

J Biol Chem. 2014 Apr 18;289(16):11194-205. doi: 10.1074/jbc.M113.529172. Epub 2014 Mar 13.

22.

Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation.

Yip KH, Kolesnikoff N, Yu C, Hauschild N, Taing H, Biggs L, Goltzman D, Gregory PA, Anderson PH, Samuel MS, Galli SJ, Lopez AF, Grimbaldeston MA.

J Allergy Clin Immunol. 2014 May;133(5):1356-64, 1364.e1-14. doi: 10.1016/j.jaci.2013.11.030. Epub 2014 Jan 22.

23.

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways.

Li X, Roslan S, Johnstone CN, Wright JA, Bracken CP, Anderson M, Bert AG, Selth LA, Anderson RL, Goodall GJ, Gregory PA, Khew-Goodall Y.

Oncogene. 2014 Jul 31;33(31):4077-88. doi: 10.1038/onc.2013.370. Epub 2013 Sep 16.

PMID:
24037528
24.

Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27.

Young JA, Ting KK, Li J, Moller T, Dunn L, Lu Y, Moses J, Prado-Lourenço L, Khachigian LM, Ng M, Gregory PA, Goodall GJ, Tsykin A, Lichtenstein I, Hahn CN, Tran N, Shackel N, Kench JG, McCaughan G, Vadas MA, Gamble JR.

Blood. 2013 Oct 17;122(16):2911-9. doi: 10.1182/blood-2012-12-473017. Epub 2013 Sep 5. Erratum in: Blood. 2014 Nov 6;124(19):3034.

PMID:
24009229
25.

Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state.

Lim YY, Wright JA, Attema JL, Gregory PA, Bert AG, Smith E, Thomas D, Lopez AF, Drew PA, Khew-Goodall Y, Goodall GJ.

J Cell Sci. 2013 May 15;126(Pt 10):2256-66. doi: 10.1242/jcs.122275. Epub 2013 Mar 22.

26.

ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression.

Ahn YH, Gibbons DL, Chakravarti D, Creighton CJ, Rizvi ZH, Adams HP, Pertsemlidis A, Gregory PA, Wright JA, Goodall GJ, Flores ER, Kurie JM.

J Clin Invest. 2012 Sep;122(9):3170-83. doi: 10.1172/JCI63608. Epub 2012 Aug 1.

27.

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.

Neilsen PM, Noll JE, Mattiske S, Bracken CP, Gregory PA, Schulz RB, Lim SP, Kumar R, Suetani RJ, Goodall GJ, Callen DF.

Oncogene. 2013 Jun 13;32(24):2992-3000. doi: 10.1038/onc.2012.305. Epub 2012 Jul 16.

PMID:
22797073
28.

Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity.

Callegari S, Gregory PA, Sykes MJ, Bellon J, Andrews S, McKinnon RA, de Barros Lopes MA.

PLoS Genet. 2012;8(6):e1002755. doi: 10.1371/journal.pgen.1002755. Epub 2012 Jun 14.

29.

MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells.

Matsushima K, Isomoto H, Yamaguchi N, Inoue N, Machida H, Nakayama T, Hayashi T, Kunizaki M, Hidaka S, Nagayasu T, Nakashima M, Ujifuku K, Mitsutake N, Ohtsuru A, Yamashita S, Korpal M, Kang Y, Gregory PA, Goodall GJ, Kohno S, Nakao K.

J Transl Med. 2011 Mar 22;9:30. doi: 10.1186/1479-5876-9-30.

30.

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.

Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ.

Mol Biol Cell. 2011 May 15;22(10):1686-98. doi: 10.1091/mbc.E11-02-0103. Epub 2011 Mar 16.

31.

The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice.

Yang Y, Ahn YH, Gibbons DL, Zang Y, Lin W, Thilaganathan N, Alvarez CA, Moreira DC, Creighton CJ, Gregory PA, Goodall GJ, Kurie JM.

J Clin Invest. 2011 Apr;121(4):1373-85. doi: 10.1172/JCI42579. Epub 2011 Mar 14.

32.

A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide.

Hu DG, Gardner-Stephen D, Severi G, Gregory PA, Treloar J, Giles GG, English DR, Hopper JL, Tilley WD, Mackenzie PI.

Mol Pharmacol. 2010 Oct;78(4):714-22. doi: 10.1124/mol.110.065953. Epub 2010 Jul 13.

PMID:
20628005
33.

Pharmacists' experience of conflict in community practice.

Austin Z, Gregory PA, Martin JC.

Res Social Adm Pharm. 2010 Mar;6(1):39-48. doi: 10.1016/j.sapharm.2009.05.002. Epub 2009 Jul 29.

PMID:
20188327
34.

A conflict management scale for pharmacy.

Austin Z, Gregory PA, Martin C.

Am J Pharm Educ. 2009 Nov 12;73(7):122.

35.

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression.

Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, Goodall GJ, Thilaganathan N, Du L, Zhang Y, Pertsemlidis A, Kurie JM.

Genes Dev. 2009 Sep 15;23(18):2140-51. doi: 10.1101/gad.1820209.

36.

The role of microRNAs in metastasis and epithelial-mesenchymal transition.

Bracken CP, Gregory PA, Khew-Goodall Y, Goodall GJ.

Cell Mol Life Sci. 2009 May;66(10):1682-99. doi: 10.1007/s00018-009-8750-1. Review.

PMID:
19153653
37.

MicroRNAs as regulators of epithelial-mesenchymal transition.

Gregory PA, Bracken CP, Bert AG, Goodall GJ.

Cell Cycle. 2008 Oct;7(20):3112-8. Epub 2008 Oct 25. Review.

PMID:
18927505
38.

The microRNA-200 family regulates epithelial to mesenchymal transition.

Paterson EL, Kolesnikoff N, Gregory PA, Bert AG, Khew-Goodall Y, Goodall GJ.

ScientificWorldJournal. 2008 Sep 21;8:901-4. doi: 10.1100/tsw.2008.115.

39.

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition.

Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, Goodall GJ.

Cancer Res. 2008 Oct 1;68(19):7846-54. doi: 10.1158/0008-5472.CAN-08-1942.

40.
41.

"I just don't know what I'm supposed to know": evaluating self-assessment skills of international pharmacy graduates in Canada.

Austin Z, Gregory PA, Galli M.

Res Social Adm Pharm. 2008 Jun;4(2):115-24. doi: 10.1016/j.sapharm.2007.03.002.

PMID:
18555965
42.

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.

Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, Vadas MA, Khew-Goodall Y, Goodall GJ.

Nat Cell Biol. 2008 May;10(5):593-601. doi: 10.1038/ncb1722. Epub 2008 Mar 30.

PMID:
18376396
43.

Evaluating the accuracy of pharmacy students' self-assessment skills.

Austin Z, Gregory PA.

Am J Pharm Educ. 2007 Oct 15;71(5):89.

44.

Pharmacy practice in times of civil crisis: The experience of SARS and the blackout in Ontario, Canada.

Austin Z, Martin JC, Gregory PA.

Res Social Adm Pharm. 2007 Sep;3(3):320-35.

PMID:
17945161
45.

Professional students' perceptions of the value, role, and impact of science in clinical education.

Austin Z, Gregory PA.

Clin Pharmacol Ther. 2007 Nov;82(5):615-20. Epub 2007 Jul 4.

PMID:
17609684
46.

Negotiation of interprofessional culture shock: the experiences of pharmacists who become physicians.

Austin Z, Gregory PA, Martin JC.

J Interprof Care. 2007 Feb;21(1):83-93.

PMID:
17365376
47.

"Testwiseness" among international pharmacy graduates and Canadian senior pharmacy students.

Mahamed A, Gregory PA, Austin Z.

Am J Pharm Educ. 2006 Dec 15;70(6):131.

48.

Characterizing the professional relationships of community pharmacists.

Austin Z, Gregory PA, Martin JC.

Res Social Adm Pharm. 2006 Dec;2(4):533-46.

PMID:
17161810
49.

The caudal-related homeodomain protein Cdx2 and hepatocyte nuclear factor 1alpha cooperatively regulate the UDP-glucuronosyltransferase 2B7 gene promoter.

Gregory PA, Gardner-Stephen DA, Rogers A, Michael MZ, Mackenzie PI.

Pharmacogenet Genomics. 2006 Jul;16(7):527-36.

PMID:
16788384
50.

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