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Items: 1 to 50 of 227

1.

Rethinking the PDH Bypass and GABA Shunt as Thiamin-Deficiency Workarounds.

Joshi J, Folz J, Gregory JF, McCarty DR, Fiehn O, Hanson AD.

Plant Physiol. 2019 Aug 13. pii: pp.00857.2019. doi: 10.1104/pp.19.00857. [Epub ahead of print] No abstract available.

2.

The Burden of Skin Disease on Deployed Servicemembers.

Gregory JF, Taylor EA, Liu YE, Love TV, Raiciulescu S, Meyerle JH.

Mil Med. 2019 May 8. pii: usz110. doi: 10.1093/milmed/usz110. [Epub ahead of print]

PMID:
31067306
3.

Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease.

Dhar I, Lysne V, Svingen GFT, Ueland PM, Gregory JF, Bønaa KH, Nygård OK.

Am J Clin Nutr. 2019 Jun 1;109(6):1546-1554. doi: 10.1093/ajcn/nqy391.

PMID:
31005968
4.

Parts-Prospecting for a High-Efficiency Thiamin Thiazole Biosynthesis Pathway.

Sun J, Sigler CL, Beaudoin GAW, Joshi J, Patterson JA, Cho KH, Ralat MA, Gregory JF 3rd, Clark DG, Deng Z, Colquhoun TA, Hanson AD.

Plant Physiol. 2019 Mar;179(3):958-968. doi: 10.1104/pp.18.01085. Epub 2018 Oct 18.

5.

Redesigning thiamin synthesis: Prospects and potential payoffs.

Hanson AD, Amthor JS, Sun J, Niehaus TD, Gregory JF 3rd, Bruner SD, Ding Y.

Plant Sci. 2018 Aug;273:92-99. doi: 10.1016/j.plantsci.2018.01.019. Epub 2018 Feb 5.

PMID:
29907313
6.

Plasma cystathionine and risk of acute myocardial infarction among patients with coronary heart disease: Results from two independent cohorts.

Dhar I, Svingen GFT, Pedersen ER, DeRatt B, Ulvik A, Strand E, Ueland PM, Bønaa KH, Gregory JF, Nygård OK.

Int J Cardiol. 2018 Sep 1;266:24-30. doi: 10.1016/j.ijcard.2018.04.083. Epub 2018 Apr 21.

7.

Evidence that the metabolite repair enzyme NAD(P)HX epimerase has a moonlighting function.

Niehaus TD, Elbadawi-Sidhu M, Huang L, Prunetti L, Gregory JF 3rd, de Crécy-Lagard V, Fiehn O, Hanson AD.

Biosci Rep. 2018 May 8;38(3). pii: BSR20180223. doi: 10.1042/BSR20180223. Print 2018 Jun 29.

8.

Suboptimal Vitamin B Intakes of Zambian Preschool Children: Evaluation of 24-Hour Dietary Recalls.

Titcomb TJ, Schmaelzle ST, Nuss ET, Gregory JF 3rd, Tanumihardjo SA.

Food Nutr Bull. 2018 Jun;39(2):281-289. doi: 10.1177/0379572118760373. Epub 2018 Mar 11.

PMID:
29528727
9.

A plastidial pantoate transporter with a potential role in pantothenate synthesis.

Huang L, Pyc M, Alseekh S, McCarty DR, de Crécy-Lagard V, Gregory JF 3rd, Henry CS, Fernie AR, Mullen RT, Hanson AD.

Biochem J. 2018 Feb 28;475(4):813-825. doi: 10.1042/BCJ20170883.

PMID:
29382740
10.

Long-term supplementation with folic acid and vitamin B-12 has no effect on circulating uric acid concentrations in Norwegian patients with coronary artery disease.

Dierkes J, Seifert R, Gregory JF, Nygård O.

Am J Clin Nutr. 2018 Jan 1;107(1):130-132. doi: 10.1093/ajcn/nqx017. No abstract available.

PMID:
29381799
11.

Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase.

Majtan T, Krijt J, Sokolová J, Křížková M, Ralat MA, Kent J, Gregory JF 3rd, Kožich V, Kraus JP.

Antioxid Redox Signal. 2018 Feb 1;28(4):311-323. doi: 10.1089/ars.2017.7009. Epub 2017 Oct 11.

PMID:
28874062
12.

Metabolomic Evaluation of the Consequences of Plasma Cystathionine Elevation in Adults with Stable Angina Pectoris.

DeRatt BN, Ralat MA, Lysne V, Tayyari F, Dhar I, Edison AS, Garrett TJ, Midttun Ø, Ueland PM, Nygård OK, Gregory JF 3rd.

J Nutr. 2017 Sep;147(9):1658-1668. doi: 10.3945/jn.117.254029. Epub 2017 Aug 9.

13.

Astronaut ophthalmic syndrome.

Zwart SR, Gibson CR, Gregory JF, Mader TH, Stover PJ, Zeisel SH, Smith SM.

FASEB J. 2017 Sep;31(9):3746-3756. doi: 10.1096/fj.201700294. Epub 2017 May 25.

PMID:
28546443
14.

Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial).

Ding Y, Pedersen ER, Svingen GF, Helgeland Ø, Gregory JF, Løland KH, Meyer K, Tell GS, Ueland PM, Nygård OK.

Circ Cardiovasc Genet. 2016 Dec;9(6):541-547. doi: 10.1161/CIRCGENETICS.116.001483. Epub 2016 Nov 21.

PMID:
27872106
15.

Does Abiotic Stress Cause Functional B Vitamin Deficiency in Plants?

Hanson AD, Beaudoin GA, McCarty DR, Gregory JF 3rd.

Plant Physiol. 2016 Dec;172(4):2082-2097. Epub 2016 Nov 2. Review.

16.

Arabidopsis TH2 Encodes the Orphan Enzyme Thiamin Monophosphate Phosphatase.

Mimura M, Zallot R, Niehaus TD, Hasnain G, Gidda SK, Nguyen TN, Anderson EM, Mullen RT, Brown G, Yakunin AF, de Crécy-Lagard V, Gregory JF 3rd, McCarty DR, Hanson AD.

Plant Cell. 2016 Oct;28(10):2683-2696. Epub 2016 Sep 27.

17.

A family of metal-dependent phosphatases implicated in metabolite damage-control.

Huang L, Khusnutdinova A, Nocek B, Brown G, Xu X, Cui H, Petit P, Flick R, Zallot R, Balmant K, Ziemak MJ, Shanklin J, de Crécy-Lagard V, Fiehn O, Gregory JF 3rd, Joachimiak A, Savchenko A, Yakunin AF, Hanson AD.

Nat Chem Biol. 2016 Aug;12(8):621-7. doi: 10.1038/nchembio.2108. Epub 2016 Jun 20.

PMID:
27322068
18.
19.

Evidence That COG0325 Proteins are involved in PLP Homeostasis.

Prunetti L, El Yacoubi B, Schiavon CR, Kirkpatrick E, Huang L, Bailly M, ElBadawi-Sidhu M, Harrison K, Gregory JF, Fiehn O, Hanson AD, de Crécy-Lagard V.

Microbiology. 2016 Feb 12. doi: 10.1099/mic.0.000255. [Epub ahead of print]

PMID:
26872910
20.

B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris.

Ding YP, Pedersen EK, Johansson S, Gregory JF 3rd, Ueland PM, Svingen GF, Helgeland Ø, Meyer K, Fredriksen Å, Nygård OK.

Nutr Metab Cardiovasc Dis. 2016 Jun;26(6):495-501. doi: 10.1016/j.numecd.2015.12.009. Epub 2015 Dec 23.

21.

Vitamin B6 nutritional status and cellular availability of pyridoxal 5'-phosphate govern the function of the transsulfuration pathway's canonical reactions and hydrogen sulfide production via side reactions.

Gregory JF, DeRatt BN, Rios-Avila L, Ralat M, Stacpoole PW.

Biochimie. 2016 Jul;126:21-6. doi: 10.1016/j.biochi.2015.12.020. Epub 2016 Jan 4. Review.

22.

Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris.

Ding Y, Svingen GF, Pedersen ER, Gregory JF, Ueland PM, Tell GS, Nygård OK.

J Am Heart Assoc. 2015 Dec 31;5(1). pii: e002621. doi: 10.1161/JAHA.115.002621.

23.

Bacterial and plant HAD enzymes catalyse a missing phosphatase step in thiamin diphosphate biosynthesis.

Hasnain G, Roje S, Sa N, Zallot R, Ziemak MJ, de Crécy-Lagard V, Gregory JF 3rd, Hanson AD.

Biochem J. 2016 Jan 15;473(2):157-66. doi: 10.1042/BJ20150805. Epub 2015 Nov 4.

PMID:
26537753
24.

Biomarkers of Nutrition for Development-Folate Review.

Bailey LB, Stover PJ, McNulty H, Fenech MF, Gregory JF 3rd, Mills JL, Pfeiffer CM, Fazili Z, Zhang M, Ueland PM, Molloy AM, Caudill MA, Shane B, Berry RJ, Bailey RL, Hausman DB, Raghavan R, Raiten DJ.

J Nutr. 2015 Jul;145(7):1636S-1680S. doi: 10.3945/jn.114.206599. Epub 2015 Jun 3. Review.

25.

Genotype, B-vitamin status, and androgens affect spaceflight-induced ophthalmic changes.

Zwart SR, Gregory JF, Zeisel SH, Gibson CR, Mader TH, Kinchen JM, Ueland PM, Ploutz-Snyder R, Heer MA, Smith SM.

FASEB J. 2016 Jan;30(1):141-8. doi: 10.1096/fj.15-278457. Epub 2015 Aug 27.

26.

Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.

Rios-Avila L, Coats B, Ralat M, Chi YY, Midttun Ø, Ueland PM, Stacpoole PW, Gregory JF 3rd.

Am J Clin Nutr. 2015 Sep;102(3):616-25. doi: 10.3945/ajcn.115.113159. Epub 2015 Jul 22.

27.

High provitamin A carotenoid serum concentrations, elevated retinyl esters, and saturated retinol-binding protein in Zambian preschool children are consistent with the presence of high liver vitamin A stores.

Mondloch S, Gannon BM, Davis CR, Chileshe J, Kaliwile C, Masi C, Rios-Avila L, Gregory JF 3rd, Tanumihardjo SA.

Am J Clin Nutr. 2015 Aug;102(2):497-504. doi: 10.3945/ajcn.115.112383. Epub 2015 Jul 15.

28.

Circulating B-vitamins and smoking habits are associated with serum polyunsaturated Fatty acids in patients with suspected coronary heart disease: a cross-sectional study.

Skeie E, Strand E, Pedersen ER, Bjørndal B, Bohov P, Berge RK, Svingen GF, Seifert R, Ueland PM, Midttun Ø, Ulvik A, Hustad S, Drevon CA, Gregory JF, Nygård O.

PLoS One. 2015 Jun 3;10(6):e0129049. doi: 10.1371/journal.pone.0129049. eCollection 2015.

29.

Direct and Functional Biomarkers of Vitamin B6 Status.

Ueland PM, Ulvik A, Rios-Avila L, Midttun Ø, Gregory JF.

Annu Rev Nutr. 2015;35:33-70. doi: 10.1146/annurev-nutr-071714-034330. Epub 2015 May 13. Review.

31.

A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis.

Frelin O, Huang L, Hasnain G, Jeffryes JG, Ziemak MJ, Rocca JR, Wang B, Rice J, Roje S, Yurgel SN, Gregory JF 3rd, Edison AS, Henry CS, de Crécy-Lagard V, Hanson AD.

Biochem J. 2015 Feb 15;466(1):137-45. doi: 10.1042/BJ20141237.

32.

Folate is absorbed across the human colon: evidence by using enteric-coated caplets containing 13C-labeled [6S]-5-formyltetrahydrofolate.

Lakoff A, Fazili Z, Aufreiter S, Pfeiffer CM, Connolly B, Gregory JF 3rd, Pencharz PB, O'Connor DL.

Am J Clin Nutr. 2014 Nov;100(5):1278-86. doi: 10.3945/ajcn.114.091785. Epub 2014 Sep 3.

33.

Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells.

DeRatt BN, Ralat MA, Kabil O, Chi YY, Banerjee R, Gregory JF 3rd.

J Nutr. 2014 Oct;144(10):1501-8. doi: 10.3945/jn.114.196808. Epub 2014 Aug 27.

34.

Targeted metabolomics and mathematical modeling demonstrate that vitamin B-6 restriction alters one-carbon metabolism in cultured HepG2 cells.

da Silva VR, Ralat MA, Quinlivan EP, DeRatt BN, Garrett TJ, Chi YY, Frederik Nijhout H, Reed MC, Gregory JF 3rd.

Am J Physiol Endocrinol Metab. 2014 Jul 1;307(1):E93-101. doi: 10.1152/ajpendo.00697.2013. Epub 2014 May 13.

35.

Erythema ab igne.

Gregory JF, Beute TC.

J Spec Oper Med. 2013 Winter;13(4):115-9.

PMID:
24227571
36.

Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women.

Yan J, Jiang X, West AA, Perry CA, Malysheva OV, Brenna JT, Stabler SP, Allen RH, Gregory JF 3rd, Caudill MA.

Am J Clin Nutr. 2013 Dec;98(6):1459-67. doi: 10.3945/ajcn.113.066092. Epub 2013 Oct 16.

37.

Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.

da Silva VR, Rios-Avila L, Lamers Y, Ralat MA, Midttun Ø, Quinlivan EP, Garrett TJ, Coats B, Shankar MN, Percival SS, Chi YY, Muller KE, Ueland PM, Stacpoole PW, Gregory JF 3rd.

J Nutr. 2013 Nov;143(11):1719-27. doi: 10.3945/jn.113.180588. Epub 2013 Aug 21.

38.
39.

A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism.

Goyer A, Hasnain G, Frelin O, Ralat MA, Gregory JF 3rd, Hanson AD.

Biochem J. 2013 Sep 15;454(3):533-42. doi: 10.1042/BJ20130516.

PMID:
23834287
40.

Sarcosine and other metabolites along the choline oxidation pathway in relation to prostate cancer--a large nested case-control study within the JANUS cohort in Norway.

de Vogel S, Ulvik A, Meyer K, Ueland PM, Nygård O, Vollset SE, Tell GS, Gregory JF 3rd, Tretli S, Bjørge T.

Int J Cancer. 2014 Jan 1;134(1):197-206. doi: 10.1002/ijc.28347. Epub 2013 Jul 27.

41.

Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects.

Gregory JF 3rd, Park Y, Lamers Y, Bandyopadhyay N, Chi YY, Lee K, Kim S, da Silva V, Hove N, Ranka S, Kahveci T, Muller KE, Stevens RD, Newgard CB, Stacpoole PW, Jones DP.

PLoS One. 2013 Jun 11;8(6):e63544. doi: 10.1371/journal.pone.0063544. Print 2013.

42.

Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells.

Zhao M, Ralat MA, da Silva V, Garrett TJ, Melnyk S, James SJ, Gregory JF 3rd.

Am J Physiol Endocrinol Metab. 2013 Feb 15;304(4):E342-51. doi: 10.1152/ajpendo.00359.2012. Epub 2012 Dec 4.

43.

Identification and characterization of the missing pyrimidine reductase in the plant riboflavin biosynthesis pathway.

Hasnain G, Frelin O, Roje S, Ellens KW, Ali K, Guan JC, Garrett TJ, de Crécy-Lagard V, Gregory JF 3rd, McCarty DR, Hanson AD.

Plant Physiol. 2013 Jan;161(1):48-56. doi: 10.1104/pp.112.208488. Epub 2012 Nov 13.

44.

Marginal vitamin B-6 deficiency decreases plasma (n-3) and (n-6) PUFA concentrations in healthy men and women.

Zhao M, Lamers Y, Ralat MA, Coats BS, Chi YY, Muller KE, Bain JR, Shankar MN, Newgard CB, Stacpoole PW, Gregory JF 3rd.

J Nutr. 2012 Oct;142(10):1791-7. Epub 2012 Sep 5.

45.

Accounting for differences in the bioactivity and bioavailability of vitamers.

Gregory JF 3rd.

Food Nutr Res. 2012;56. doi: 10.3402/fnr.v56i0.5809. Epub 2012 Apr 2.

46.

Global hypothesis testing for high-dimensional repeated measures outcomes.

Chi YY, Gribbin M, Lamers Y, Gregory JF 3rd, Muller KE.

Stat Med. 2012 Apr 13;31(8):724-42. doi: 10.1002/sim.4435. Epub 2011 Dec 9.

47.

S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial.

Medici V, Virata MC, Peerson JM, Stabler SP, French SW, Gregory JF 3rd, Albanese A, Bowlus CL, Devaraj S, Panacek EA, Richards JR, Halsted CH.

Alcohol Clin Exp Res. 2011 Nov;35(11):1960-5. doi: 10.1111/j.1530-0277.2011.01547.x.

48.

Comparative genomics and functional analysis of the NiaP family uncover nicotinate transporters from bacteria, plants, and mammals.

Jeanguenin L, Lara-Núñez A, Rodionov DA, Osterman AL, Komarova NY, Rentsch D, Gregory JF 3rd, Hanson AD.

Funct Integr Genomics. 2012 Mar;12(1):25-34. doi: 10.1007/s10142-011-0255-y. Epub 2011 Sep 28.

PMID:
21953179
49.

Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers.

Neuhouser ML, Nijhout HF, Gregory JF 3rd, Reed MC, James SJ, Liu A, Shane B, Ulrich CM.

Cancer Epidemiol Biomarkers Prev. 2011 Sep;20(9):1912-7. doi: 10.1158/1055-9965.EPI-10-1352. Epub 2011 Jul 13.

50.

Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice.

Chew TW, Jiang X, Yan J, Wang W, Lusa AL, Carrier BJ, West AA, Malysheva OV, Brenna JT, Gregory JF 3rd, Caudill MA.

J Nutr. 2011 Aug;141(8):1475-81. doi: 10.3945/jn.111.138859. Epub 2011 Jun 22.

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