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Items: 1 to 50 of 79

1.

Deep-sequencing study of HCV G4a resistance-associated substitutions in Egyptian patients failing DAA treatment.

Amer F, Yousif MM, Hammad NM, Garcia-Cehic D, Gregori J, Rando-Segura A, Nieto-Aponte L, Esteban JI, Rodriguez-Frias F, Quer J.

Infect Drug Resist. 2019 Sep 10;12:2799-2807. doi: 10.2147/IDR.S214735. eCollection 2019.

2.

Synergistic lethal mutagenesis of hepatitis C virus.

Gallego I, Soria ME, Gregori J, de Ávila AI, García-Crespo C, Moreno E, Gadea I, Esteban J, Fernández-Roblas R, Esteban JI, Gómez J, Quer J, Domingo E, Perales C.

Antimicrob Agents Chemother. 2019 Sep 30. pii: AAC.01653-19. doi: 10.1128/AAC.01653-19. [Epub ahead of print]

PMID:
31570400
3.

The increasing impact of lethal mutagenesis of viruses.

Perales C, Gallego I, de Ávila AI, Soria ME, Gregori J, Quer J, Domingo E.

Future Med Chem. 2019 Jul;11(13):1645-1657. doi: 10.4155/fmc-2018-0457.

PMID:
31469331
4.

The Critical Role of Codon Composition on the Translation Efficiency Robustness of the Hepatitis A Virus Capsid.

D'Andrea L, Pérez-Rodríguez FJ, de Castellarnau M, Guix S, Ribes E, Quer J, Gregori J, Bosch A, Pintó RM.

Genome Biol Evol. 2019 Sep 1;11(9):2439-2456. doi: 10.1093/gbe/evz146.

5.

Whole-genome characterization and resistance-associated substitutions in a new HCV genotype 1 subtype.

von Massow G, Garcia-Cehic D, Gregori J, Rodriguez-Frias F, Macià MD, Escarda A, Esteban JI, Quer J.

Infect Drug Resist. 2019 Apr 24;12:947-955. doi: 10.2147/IDR.S195441. eCollection 2019.

6.

Characterization of hepatitis B virus X gene quasispecies complexity in mono-infection and hepatitis delta virus superinfection.

Godoy C, Tabernero D, Sopena S, Gregori J, Cortese MF, González C, Casillas R, Yll M, Rando A, López-Martínez R, Quer J, González-Aseguinolaza G, Esteban R, Riveiro-Barciela M, Buti M, Rodríguez-Frías F.

World J Gastroenterol. 2019 Apr 7;25(13):1566-1579. doi: 10.3748/wjg.v25.i13.1566.

7.

Correction: Characterization of intra- and inter-host norovirus P2 genetic variability in linked individuals by amplicon sequencing.

Sabrià A, Pintó RM, Bosch A, Quer J, Garcia-Cehic D, Gregori J, Dominguez A, Carol M, Sala-Farré MR, Guix S; Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia.

PLoS One. 2018 Dec 19;13(12):e0209714. doi: 10.1371/journal.pone.0209714. eCollection 2018.

8.

Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant.

Perales C, Chen Q, Soria ME, Gregori J, Garcia-Cehic D, Nieto-Aponte L, Castells L, Imaz A, Llorens-Revull M, Domingo E, Buti M, Esteban JI, Rodriguez-Frias F, Quer J.

Infect Drug Resist. 2018 Nov 8;11:2207-2210. doi: 10.2147/IDR.S172226. eCollection 2018.

9.

Evidence for positive selection of hepatitis A virus antigenic variants in vaccinated men-having-sex-with men patients: Implications for immunization policies.

Sabrià A, Gregori J, Garcia-Cehic D, Guix S, Pumarola T, Manzanares-Laya S, Caylà JA, Bosch A, Quer J, Pintó RM.

EBioMedicine. 2019 Jan;39:348-357. doi: 10.1016/j.ebiom.2018.11.023. Epub 2018 Nov 22.

10.

Hepatitis C virus intrinsic molecular determinants may contribute to the development of cholestatic hepatitis after liver transplantation.

Gambato M, Gregori J, Quer J, Koutsoudakis G, González P, Caro-Pérez N, García-Cehic D, García-González N, González-Candelas F, Esteban JI, Crespo G, Navasa M, Forns X, Pérez-Del-Pulgar S.

J Gen Virol. 2019 Jan;100(1):63-68. doi: 10.1099/jgv.0.001175. Epub 2018 Nov 19.

PMID:
30451649
11.

Thrombotic thrombocytopenic purpura relapse induced by acute hepatitis E transmitted by cryosupernatant plasma and successfully controlled with ribavirin.

Riveiro-Barciela M, Bes M, Quer J, Valcarcel D, Piriz S, Gregori J, Llorens M, Salcedo MT, Piron M, Esteban R, Buti M, Sauleda S.

Transfusion. 2018 Nov;58(11):2501-2505. doi: 10.1111/trf.14831. Epub 2018 Oct 4.

PMID:
30284732
12.

Rare haplotype load as marker for lethal mutagenesis.

Gregori J, Soria ME, Gallego I, Guerrero-Murillo M, Esteban JI, Quer J, Perales C, Domingo E.

PLoS One. 2018 Oct 3;13(10):e0204877. doi: 10.1371/journal.pone.0204877. eCollection 2018.

13.

Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus.

Soria ME, Gregori J, Chen Q, García-Cehic D, Llorens M, de Ávila AI, Beach NM, Domingo E, Rodríguez-Frías F, Buti M, Esteban R, Esteban JI, Quer J, Perales C.

BMC Infect Dis. 2018 Sep 3;18(1):446. doi: 10.1186/s12879-018-3356-6.

14.

Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals.

Perpiñán E, Caro-Pérez N, García-González N, Gregori J, González P, Bartres C, Soria ME, Perales C, Lens S, Mariño Z, Londoño MC, Ariza X, Koutsoudakis G, Quer J, González-Candelas F, Forns X, Pérez-Del-Pulgar S.

J Viral Hepat. 2018 Dec;25(12):1515-1525. doi: 10.1111/jvh.12986. Epub 2018 Oct 4.

PMID:
30141252
15.

Extracellular HMGA1 Promotes Tumor Invasion and Metastasis in Triple-Negative Breast Cancer.

Méndez O, Peg V, Salvans C, Pujals M, Fernández Y, Abasolo I, Pérez J, Matres A, Valeri M, Gregori J, Villarreal L, Schwartz S Jr, Ramon Y Cajal S, Tabernero J, Cortés J, Arribas J, Villanueva J.

Clin Cancer Res. 2018 Dec 15;24(24):6367-6382. doi: 10.1158/1078-0432.CCR-18-0517. Epub 2018 Aug 22.

PMID:
30135148
16.

Resistance of high fitness hepatitis C virus to lethal mutagenesis.

Gallego I, Gregori J, Soria ME, García-Crespo C, García-Álvarez M, Gómez-González A, Valiergue R, Gómez J, Esteban JI, Quer J, Domingo E, Perales C.

Virology. 2018 Oct;523:100-109. doi: 10.1016/j.virol.2018.07.030. Epub 2018 Aug 11.

PMID:
30107298
17.

Characterization of intra- and inter-host norovirus P2 genetic variability in linked individuals by amplicon sequencing.

Sabrià A, Pintó RM, Bosch A, Quer J, Garcia-Cehic D, Gregori J, Dominguez A, Carol M, Sala-Farré MR, Guix S; Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia.

PLoS One. 2018 Aug 9;13(8):e0201850. doi: 10.1371/journal.pone.0201850. eCollection 2018. Erratum in: PLoS One. 2018 Dec 19;13(12):e0209714.

18.

HIV-1 Protease Evolvability Is Affected by Synonymous Nucleotide Recoding.

Nevot M, Jordan-Paiz A, Martrus G, Andrés C, García-Cehic D, Gregori J, Franco S, Quer J, Martinez MA.

J Virol. 2018 Jul 31;92(16). pii: e00777-18. doi: 10.1128/JVI.00777-18. Print 2018 Aug 15.

19.

Homogeneous application of imaging criteria in a multicenter trial supported by investigator training: A report from the WAKE-UP study.

Galinovic I, Dicken V, Heitz J, Klein J, Puig J, Guibernau J, Kemmling A, Gellissen S, Villringer K, Neeb L, Gregori J, Weiler F, Pedraza S, Thomalla G, Fiehler J, Gerloff C, Fiebach JB; WAKE-UP Investigators.

Eur J Radiol. 2018 Jul;104:115-119. doi: 10.1016/j.ejrad.2018.05.011. Epub 2018 May 15.

PMID:
29857856
20.

Detection of hyper-conserved regions in hepatitis B virus X gene potentially useful for gene therapy.

González C, Tabernero D, Cortese MF, Gregori J, Casillas R, Riveiro-Barciela M, Godoy C, Sopena S, Rando A, Yll M, Lopez-Martinez R, Quer J, Esteban R, Buti M, Rodríguez-Frías F.

World J Gastroenterol. 2018 May 21;24(19):2095-2107. doi: 10.3748/wjg.v24.i19.2095.

21.

MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset.

Thomalla G, Simonsen CZ, Boutitie F, Andersen G, Berthezene Y, Cheng B, Cheripelli B, Cho TH, Fazekas F, Fiehler J, Ford I, Galinovic I, Gellissen S, Golsari A, Gregori J, Günther M, Guibernau J, Häusler KG, Hennerici M, Kemmling A, Marstrand J, Modrau B, Neeb L, Perez de la Ossa N, Puig J, Ringleb P, Roy P, Scheel E, Schonewille W, Serena J, Sunaert S, Villringer K, Wouters A, Thijs V, Ebinger M, Endres M, Fiebach JB, Lemmens R, Muir KW, Nighoghossian N, Pedraza S, Gerloff C; WAKE-UP Investigators.

N Engl J Med. 2018 Aug 16;379(7):611-622. doi: 10.1056/NEJMoa1804355. Epub 2018 May 16.

22.

Analysis of hepatitis B virus preS1 variability and prevalence of the rs2296651 polymorphism in a Spanish population.

Casillas R, Tabernero D, Gregori J, Belmonte I, Cortese MF, González C, Riveiro-Barciela M, López RM, Quer J, Esteban R, Buti M, Rodríguez-Frías F.

World J Gastroenterol. 2018 Feb 14;24(6):680-692. doi: 10.3748/wjg.v24.i6.680.

23.

Arterial Spin Labeling Cerebral Perfusion Magnetic Resonance Imaging in Migraine Aura: An Observational Study.

Wolf ME, Okazaki S, Eisele P, Rossmanith C, Gregori J, Griebe M, Günther M, Gass A, Hennerici MG, Szabo K, Kern R.

J Stroke Cerebrovasc Dis. 2018 May;27(5):1262-1266. doi: 10.1016/j.jstrokecerebrovasdis.2017.12.002. Epub 2018 Jan 10.

PMID:
29331612
24.

Hepatitis C virus deep sequencing for sub-genotype identification in mixed infections: A real-life experience.

Del Campo JA, Parra-Sánchez M, Figueruela B, García-Rey S, Quer J, Gregori J, Bernal S, Grande L, Palomares JC, Romero-Gómez M.

Int J Infect Dis. 2018 Feb;67:114-117. doi: 10.1016/j.ijid.2017.12.016. Epub 2017 Dec 15.

25.

New hepatitis C virus genotype 1 subtype naturally harbouring resistance-associated mutations to NS5A inhibitors.

Ordeig L, Garcia-Cehic D, Gregori J, Soria ME, Nieto-Aponte L, Perales C, Llorens M, Chen Q, Riveiro-Barciela M, Buti M, Esteban R, Esteban JI, Rodriguez-Frias F, Quer J.

J Gen Virol. 2018 Jan;99(1):97-102. doi: 10.1099/jgv.0.000996. Epub 2017 Dec 14.

PMID:
29239718
26.

Quantitative characterization of hepatitis delta virus genome edition by next-generation sequencing.

Sopena S, Godoy C, Tabernero D, Homs M, Gregori J, Riveiro-Barciela M, Ruiz A, Esteban R, Buti M, Rodríguez-Frías F.

Virus Res. 2018 Jan 2;243:52-59. doi: 10.1016/j.virusres.2017.10.003. Epub 2017 Oct 4.

PMID:
28988126
27.

Epidemiological trends of HIV-1 infection in blood donors from Catalonia, Spain (2005-2014).

Bes M, Piron M, Casamitjana N, Gregori J, Esteban JI, Ribera E, Quer J, Puig L, Sauleda S.

Transfusion. 2017 Sep;57(9):2164-2173. doi: 10.1111/trf.14195. Epub 2017 Jul 5.

PMID:
28681400
28.

Phylogenetic analysis of an epidemic outbreak of acute hepatitis C in HIV-infected patients by ultra-deep pyrosequencing.

Caro-Pérez N, Martínez-Rebollar M, Gregori J, Quer J, González P, Gambato M, García-González N, González-Candelas F, Costa J, Esteban JI, Mallolas J, Forns X, Laguno M, Pérez-Del-Pulgar S.

J Clin Virol. 2017 Jul;92:42-47. doi: 10.1016/j.jcv.2017.05.008. Epub 2017 May 10.

PMID:
28521213
29.

Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy.

Shirvani-Dastgerdi E, Winer BY, Celià-Terrassa T, Kang Y, Tabernero D, Yagmur E, Rodríguez-Frías F, Gregori J, Luedde T, Trautwein C, Ploss A, Tacke F.

J Hepatol. 2017 Aug;67(2):246-254. doi: 10.1016/j.jhep.2017.03.027. Epub 2017 Apr 7.

30.

Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment.

Moreno E, Gallego I, Gregori J, Lucía-Sanz A, Soria ME, Castro V, Beach NM, Manrubia S, Quer J, Esteban JI, Rice CM, Gómez J, Gastaminza P, Domingo E, Perales C.

J Virol. 2017 Apr 28;91(10). pii: e02505-16. doi: 10.1128/JVI.02505-16. Print 2017 May 15.

31.

High HCV subtype heterogeneity in a chronically infected general population revealed by high-resolution hepatitis C virus subtyping.

Rodriguez-Frias F, Nieto-Aponte L, Gregori J, Garcia-Cehic D, Casillas R, Tabernero D, Homs M, Blasi M, Vila M, Chen Q, Vargas V, Castells L, Viladomiu L, Genesca J, Minguez B, Augustin S, Riveiro-Barciela M, Carbonell J, Perales C, Soria ME, Asensio M, Llorens M, Ordeig L, Godoy C, Buti M, Esteban R, Pumarola T, Esteban JI, Quer J.

Clin Microbiol Infect. 2017 Oct;23(10):775.e1-775.e6. doi: 10.1016/j.cmi.2017.02.007. Epub 2017 Feb 10.

32.

Deep sequencing in the management of hepatitis virus infections.

Quer J, Rodríguez-Frias F, Gregori J, Tabernero D, Soria ME, García-Cehic D, Homs M, Bosch A, Pintó RM, Esteban JI, Domingo E, Perales C.

Virus Res. 2017 Jul 15;239:115-125. doi: 10.1016/j.virusres.2016.12.020. Epub 2016 Dec 28. Review.

PMID:
28040474
33.

Assessment of a Novel Automatic Real-Time PCR Assay on the Cobas 4800 Analyzer as a Screening Platform for Hepatitis C Virus Genotyping in Clinical Practice: Comparison with Massive Sequencing.

Nieto-Aponte L, Quer J, Ruiz-Ripa A, Tabernero D, Gonzalez C, Gregori J, Vila M, Asensio M, Garcia-Cehic D, Ruiz G, Chen Q, Ordeig L, Llorens M, Saez M, Esteban JI, Esteban R, Buti M, Pumarola T, Rodriguez-Frias F.

J Clin Microbiol. 2017 Feb;55(2):504-509. doi: 10.1128/JCM.01960-16. Epub 2016 Dec 7.

34.

New real-time-PCR method to identify single point mutations in hepatitis C virus.

Chen Q, Belmonte I, Buti M, Nieto L, Garcia-Cehic D, Gregori J, Perales C, Ordeig L, Llorens M, Soria ME, Esteban R, Esteban JI, Rodriguez-Frias F, Quer J.

World J Gastroenterol. 2016 Nov 21;22(43):9604-9612.

35.

Improving virus production through quasispecies genomic selection and molecular breeding.

Pérez-Rodríguez FJ, D'Andrea L, de Castellarnau M, Costafreda MI, Guix S, Ribes E, Quer J, Gregori J, Bosch A, Pintó RM.

Sci Rep. 2016 Nov 3;6:35962. doi: 10.1038/srep35962.

36.

Red blood cell transfusion-transmitted acute hepatitis E in an immunocompetent subject in Europe: a case report.

Riveiro-Barciela M, Sauleda S, Quer J, Salvador F, Gregori J, Pirón M, Rodríguez-Frías F, Buti M.

Transfusion. 2017 Feb;57(2):244-247. doi: 10.1111/trf.13876. Epub 2016 Oct 26.

PMID:
27785789
37.

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

de Ávila AI, Gallego I, Soria ME, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C.

PLoS One. 2016 Oct 18;11(10):e0164691. doi: 10.1371/journal.pone.0164691. eCollection 2016.

38.

Evidence of an Exponential Decay Pattern of the Hepatitis Delta Virus Evolution Rate and Fluctuations in Quasispecies Complexity in Long-Term Studies of Chronic Delta Infection.

Homs M, Rodriguez-Frias F, Gregori J, Ruiz A, Reimundo P, Casillas R, Tabernero D, Godoy C, Barakat S, Quer J, Riveiro-Barciela M, Roggendorf M, Esteban R, Buti M.

PLoS One. 2016 Jun 30;11(6):e0158557. doi: 10.1371/journal.pone.0158557. eCollection 2016.

39.

Correction for Quer at al., High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods.

Quer J, Gregori J, Rodríguez-Frias F, Buti M, Madejon A, Perez-Del-Pulgar S, Garcia-Cehic D, Casillas R, Blasi M, Homs M, Tabernero D, Alvarez-Tejado M, Muñoz JM, Cubero M, Caballero A, delCampo JA, Domingo E, Belmonte I, Nieto L, Lens S, Muñoz-de-Rueda P, Sanz-Cameno P, Sauleda S, Bes M, Gomez J, Briones C, Perales C, Sheldon J, Castells L, Viladomiu L, Salmeron J, Ruiz-Extremera A, Quiles-Pérez R, Moreno-Otero R, López-Rodríguez R, Allende H, Romero-Gómez M, Guardia J, Esteban R, Garcia-Samaniego J, Forns X, Esteban JI.

J Clin Microbiol. 2016 Jul;54(7):1933. doi: 10.1128/JCM.01007-16. No abstract available.

40.

Defining the optimal sequence for the systemic treatment of metastatic breast cancer.

Mestres JA, iMolins AB, Martínez LC, López-Muñiz JI, Gil EC, de Juan Ferré A, Del Barco Berrón S, Pérez YF, Mata JG, Palomo AG, Gregori JG, Pardo PG, Mañas JJ, Hernández AL, de Dueñas EM, Jáñez NM, Murillo SM, Bofill JS, Auñón PZ, Sanchez-Rovira P.

Clin Transl Oncol. 2017 Feb;19(2):149-161. doi: 10.1007/s12094-016-1520-2. Epub 2016 Jun 17.

41.

Automated quality assessment in three-dimensional breast ultrasound images.

Schwaab J, Diez Y, Oliver A, Martí R, van Zelst J, Gubern-Mérida A, Mourri AB, Gregori J, Günther M.

J Med Imaging (Bellingham). 2016 Apr;3(2):027002. doi: 10.1117/1.JMI.3.2.027002. Epub 2016 Apr 25.

42.

Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus.

Gallego I, Sheldon J, Moreno E, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C.

Antimicrob Agents Chemother. 2016 May 23;60(6):3786-93. doi: 10.1128/AAC.00581-16. Print 2016 Jun.

43.

Viral quasispecies complexity measures.

Gregori J, Perales C, Rodriguez-Frias F, Esteban JI, Quer J, Domingo E.

Virology. 2016 Jun;493:227-37. doi: 10.1016/j.virol.2016.03.017. Epub 2016 Apr 6. Review.

44.

Identification of hepatitis C virus genotype 3 by a commercial assay challenged by natural polymorphisms detected in Spain from patients with diverse origins.

Saludes V, Quer J, Gregori J, Bascuñana E, García-Cehic D, Esteban JI, Ausina V, Martró E.

J Clin Virol. 2016 May;78:14-9. doi: 10.1016/j.jcv.2016.02.024. Epub 2016 Feb 28.

PMID:
26946155
45.

Complex Genotype Mixtures Analyzed by Deep Sequencing in Two Different Regions of Hepatitis B Virus.

Caballero A, Gregori J, Homs M, Tabernero D, Gonzalez C, Quer J, Blasi M, Casillas R, Nieto L, Riveiro-Barciela M, Esteban R, Buti M, Rodriguez-Frias F.

PLoS One. 2015 Dec 29;10(12):e0144816. doi: 10.1371/journal.pone.0144816. eCollection 2015.

46.

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications.

Perales C, Quer J, Gregori J, Esteban JI, Domingo E.

Viruses. 2015 Nov 6;7(11):5746-66. doi: 10.3390/v7112902. Review.

47.

Prediction of Early Reperfusion From Repeated Arterial Spin Labeling Perfusion Magnetic Resonance Imaging During Intravenous Thrombolysis.

Okazaki S, Griebe M, Gregori J, Günther M, Sauter-Servaes J, Wolf ME, Gass A, Hennerici MG, Szabo K, Kern R.

Stroke. 2016 Jan;47(1):247-50. doi: 10.1161/STROKEAHA.115.011482. Epub 2015 Oct 29.

PMID:
26514187
48.

Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors.

Pérez-del-Pulgar S, Gregori J, Rodríguez-Frías F, González P, García-Cehic D, Ramírez S, Casillas R, Domingo E, Esteban JI, Forns X, Quer J.

J Gen Virol. 2015 Dec;96(12):3493-8.

PMID:
26395289
49.

Breast cancer in pregnancy: an institutional experience.

Blanquisett AH, Vicent CH, Gregori JG, Zotano ÁG, Porta VG, Simón AR.

Ecancermedicalscience. 2015 Jul 8;9:551. doi: 10.3332/ecancer.2015.551. eCollection 2015.

50.

Clinical application of estimating hepatitis B virus quasispecies complexity by massive sequencing: correlation between natural evolution and on-treatment evolution.

Homs M, Caballero A, Gregori J, Tabernero D, Quer J, Nieto L, Esteban R, Buti M, Rodriguez-Frias F.

PLoS One. 2014 Nov 13;9(11):e112306. doi: 10.1371/journal.pone.0112306. eCollection 2014.

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