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Squamous Cell Transformation of Primary Lung Adenocarcinoma in a Patient With EML4-ALK Fusion Variant 5 Refractory to ALK Inhibitors.

Gong J, Gregg JP, Ma W, Yoneda K, Moore EH, Daly ME, Zhang Y, Williams MJ, Li T.

J Natl Compr Canc Netw. 2019 Apr 1;17(4):297-301. doi: 10.6004/jnccn.2019.7291.


Multiple configurations of EGFR exon 20 resistance mutations after first- and third-generation EGFR TKI treatment affect treatment options in NSCLC.

Goldberg ME, Montesion M, Young L, Suh J, Greenbowe J, Kennedy M, Giaccone G, Akerley WL, Dowlati A, Creelan BC, Hicks JK, Hesketh PJ, Kelly KL, Riess JW, Miller VA, Stephens PJ, Frampton GM, Ali S, Gregg JP, Albacker LA.

PLoS One. 2018 Nov 27;13(11):e0208097. doi: 10.1371/journal.pone.0208097. eCollection 2018.


Clinical utility of tumor genomic profiling in patients with high plasma circulating tumor DNA burden or metabolically active tumors.

Zhou C, Yuan Z, Ma W, Qi L, Mahavongtrakul A, Li Y, Li H, Gong J, Fan RR, Li J, Molmen M, Clark TA, Pavlick D, Frampton GM, Forcier B, Moore EH, Shelton DK, Cooke M, Ali SM, Miller VA, Gregg JP, Stephens PJ, Li T.

J Hematol Oncol. 2018 Nov 6;11(1):129. doi: 10.1186/s13045-018-0671-8.


Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

Clark TA, Chung JH, Kennedy M, Hughes JD, Chennagiri N, Lieber DS, Fendler B, Young L, Zhao M, Coyne M, Breese V, Young G, Donahue A, Pavlick D, Tsiros A, Brennan T, Zhong S, Mughal T, Bailey M, He J, Roels S, Frampton GM, Spoerke JM, Gendreau S, Lackner M, Schleifman E, Peters E, Ross JS, Ali SM, Miller VA, Gregg JP, Stephens PJ, Welsh A, Otto GA, Lipson D.

J Mol Diagn. 2018 Sep;20(5):686-702. doi: 10.1016/j.jmoldx.2018.05.004. Epub 2018 Jun 22.


High frequency of the PNPLA3 rs738409 [G] single-nucleotide polymorphism in Hmong individuals as a potential basis for a predisposition to chronic liver disease.

Tepper CG, Dang JHT, Stewart SL, Fang DM, Wong KA, Liu SY, Davis RR, Dao DY, Gregg JP, Török NJ, Chen MS Jr.

Cancer. 2018 Apr 1;124 Suppl 7:1583-1589. doi: 10.1002/cncr.31122.


KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer.

Knight JF, Sung VYC, Kuzmin E, Couzens AL, de Verteuil DA, Ratcliffe CDH, Coelho PP, Johnson RM, Samavarchi-Tehrani P, Gruosso T, Smith HW, Lee W, Saleh SM, Zuo D, Zhao H, Guiot MC, Davis RR, Gregg JP, Moraes C, Gingras AC, Park M.

Cell Rep. 2018 Mar 20;22(12):3191-3205. doi: 10.1016/j.celrep.2018.02.095.


Optimal Molecular Methods in Detecting p190 (BCR-ABL) Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature.

Sonu RJ, Jonas BA, Dwyre DM, Gregg JP, Rashidi HH.

Case Rep Hematol. 2015;2015:458052. doi: 10.1155/2015/458052. Epub 2015 Apr 8.


Transgenic mammary epithelial osteopontin (spp1) expression induces proliferation and alveologenesis.

Hubbard NE, Chen QJ, Sickafoose LK, Wood MB, Gregg JP, Abrahamsson NM, Engelberg JA, Walls JE, Borowsky AD.

Genes Cancer. 2013 May;4(5-6):201-12. doi: 10.1177/1947601913496813.


Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer.

Knight JF, Lesurf R, Zhao H, Pinnaduwage D, Davis RR, Saleh SM, Zuo D, Naujokas MA, Chughtai N, Herschkowitz JI, Prat A, Mulligan AM, Muller WJ, Cardiff RD, Gregg JP, Andrulis IL, Hallett MT, Park M.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):E1301-10. doi: 10.1073/pnas.1210353110. Epub 2013 Mar 18.


Modulation of blood cell gene expression by DHA supplementation in hypertriglyceridemic men.

Dawson K, Zhao L, Adkins Y, Vemuri M, Rodriguez RL, Gregg JP, Kelley DS, Hwang DH.

J Nutr Biochem. 2012 Jun;23(6):616-21. doi: 10.1016/j.jnutbio.2011.03.004. Epub 2011 Jul 19.


Congenital myasthenic syndrome associated with epidermolysis bullosa caused by homozygous mutations in PLEC1 and CHRNE.

Maselli RA, Arredondo J, Cagney O, Mozaffar T, Skinner S, Yousif S, Davis RR, Gregg JP, Sivak M, Konia TH, Thomas K, Wollmann RL.

Clin Genet. 2011 Nov;80(5):444-51. doi: 10.1111/j.1399-0004.2010.01602.x. Epub 2010 Dec 22.


Developmental regulation of gene expression and astrocytic processes may explain selective hippocampal vulnerability.

Lavenex P, Sugden SG, Davis RR, Gregg JP, Lavenex PB.

Hippocampus. 2011 Feb;21(2):142-9. doi: 10.1002/hipo.20730.


Correlations between gene expression and mercury levels in blood of boys with and without autism.

Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp FR.

Neurotox Res. 2011 Jan;19(1):31-48. doi: 10.1007/s12640-009-9137-7. Epub 2009 Nov 24.


Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls.

Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP, Ashwood P, Jickling G, Van de Water J, Sharp FR.

Neurotox Res. 2011 Jan;19(1):1-13. doi: 10.1007/s12640-009-9126-x. Epub 2009 Nov 17.


Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood.

Stamova BS, Apperson M, Walker WL, Tian Y, Xu H, Adamczy P, Zhan X, Liu DZ, Ander BP, Liao IH, Gregg JP, Turner RJ, Jickling G, Lit L, Sharp FR.

BMC Med Genomics. 2009 Aug 5;2:49. doi: 10.1186/1755-8794-2-49.


Altered gene expression and function of peripheral blood natural killer cells in children with autism.

Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P.

Brain Behav Immun. 2009 Jan;23(1):124-33. doi: 10.1016/j.bbi.2008.08.001. Epub 2008 Aug 14.


Gene expression in peripheral blood differs after cardioembolic compared with large-vessel atherosclerotic stroke: biomarkers for the etiology of ischemic stroke.

Xu H, Tang Y, Liu DZ, Ran R, Ander BP, Apperson M, Liu XS, Khoury JC, Gregg JP, Pancioli A, Jauch EC, Wagner KR, Verro P, Broderick JP, Sharp FR.

J Cereb Blood Flow Metab. 2008 Jul;28(7):1320-8. doi: 10.1038/jcbfm.2008.22. Epub 2008 Apr 2.


Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons.

Liu DZ, Cheng XY, Ander BP, Xu H, Davis RR, Gregg JP, Sharp FR.

Neurobiol Dis. 2008 May;30(2):201-11. doi: 10.1016/j.nbd.2008.01.006. Epub 2008 Feb 9.


Gene expression changes in children with autism.

Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp FR.

Genomics. 2008 Jan;91(1):22-9. Epub 2007 Nov 14.


EMT tumorigenesis in the mouse mammary gland.

Damonte P, Gregg JP, Borowsky AD, Keister BA, Cardiff RD.

Lab Invest. 2007 Dec;87(12):1218-26. Epub 2007 Oct 8.


High throughput genetic analysis of congenital myasthenic syndromes using resequencing microarrays.

Denning L, Anderson JA, Davis R, Gregg JP, Kuzdenyi J, Maselli RA.

PLoS One. 2007 Sep 19;2(9):e918.


Selective high-affinity ligand antibody mimics for cancer diagnosis and therapy: initial application to lymphoma/leukemia.

Balhorn R, Hok S, Burke PA, Lightstone FC, Cosman M, Zemla A, Mirick G, Perkins J, Natarajan A, Corzett M, DeNardo SJ, Albrecht H, Gregg JP, DeNardo GL.

Clin Cancer Res. 2007 Sep 15;13(18 Pt 2):5621s-5628s.


Exposure of myeloid dendritic cells to exogenous or endogenous IL-10 during maturation determines their longevity.

Chang WL, Baumgarth N, Eberhardt MK, Lee CY, Baron CA, Gregg JP, Barry PA.

J Immunol. 2007 Jun 15;178(12):7794-804.


Heterogeneity of mammary lesions represent molecular differences.

Namba R, Maglione JE, Davis RR, Baron CA, Liu S, Carmack CE, Young LJ, Borowsky AD, Cardiff RD, Gregg JP.

BMC Cancer. 2006 Dec 5;6:275.


Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth.

Yen L, Cao Z, Wu X, Ingalla ER, Baron C, Young LJ, Gregg JP, Cardiff RD, Borowsky AD, Sweeney C, Carraway KL 3rd.

Cancer Res. 2006 Dec 1;66(23):11279-86.


Preclinical imaging of mammary intraepithelial neoplasia with positron emission tomography.

Abbey CK, Borowsky AD, Gregg JP, Cardiff RD, Cherry SR.

J Mammary Gland Biol Neoplasia. 2006 Apr;11(2):137-49. Review.


Histopathology as a predictive biomarker: strengths and limitations.

Cardiff RD, Gregg JP, Miller JW, Axelrod DE, Borowsky AD.

J Nutr. 2006 Oct;136(10):2673S-5S. No abstract available.


Utilization of lymphoblastoid cell lines as a system for the molecular modeling of autism.

Baron CA, Liu SY, Hicks C, Gregg JP.

J Autism Dev Disord. 2006 Nov;36(8):973-82.


Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal.

Goth SR, Chu RA, Gregg JP, Cherednichenko G, Pessah IN.

Environ Health Perspect. 2006 Jul;114(7):1083-91.


Characterization of MUC1 glycoprotein on prostate cancer for selection of targeting molecules.

Burke PA, Gregg JP, Bakhtiar B, Beckett LA, Denardo GL, Albrecht H, De Vere White RW, De Nardo SJ.

Int J Oncol. 2006 Jul;29(1):49-55.


Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ.

Namba R, Young LJ, Abbey CK, Kim L, Damonte P, Borowsky AD, Qi J, Tepper CG, MacLeod CL, Cardiff RD, Gregg JP.

Clin Cancer Res. 2006 Apr 15;12(8):2613-21.


Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes.

Baron CA, Tepper CG, Liu SY, Davis RR, Wang NJ, Schanen NC, Gregg JP.

Hum Mol Genet. 2006 Mar 15;15(6):853-69. Epub 2006 Jan 30.


Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study.

Tang Y, Xu H, Du X, Lit L, Walker W, Lu A, Ran R, Gregg JP, Reilly M, Pancioli A, Khoury JC, Sauerbeck LR, Carrozzella JA, Spilker J, Clark J, Wagner KR, Jauch EC, Chang DJ, Verro P, Broderick JP, Sharp FR.

J Cereb Blood Flow Metab. 2006 Aug;26(8):1089-102. Epub 2006 Jan 4.


Retinoid x receptor agonists increase bcl2a1 expression and decrease apoptosis of naive T lymphocytes.

Rasooly R, Schuster GU, Gregg JP, Xiao JH, Chandraratna RA, Stephensen CB.

J Immunol. 2005 Dec 15;175(12):7916-29.


Cyclin E both regulates and is regulated by calpain 2, a protease associated with metastatic breast cancer phenotype.

Libertini SJ, Robinson BS, Dhillon NK, Glick D, George M, Dandekar S, Gregg JP, Sawai E, Mudryj M.

Cancer Res. 2005 Dec 1;65(23):10700-8.


Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ.

Namba R, Young LJ, Maglione JE, McGoldrick ET, Liu S, Wurz GT, DeGregorio MW, Borowsky AD, MacLeod CL, Cardiff RD, Gregg JP.

Breast Cancer Res. 2005;7(6):R881-9. Epub 2005 Sep 13.


Enhancement of the therapeutic index: from nonmyeloablative and myeloablative toward pretargeted radioimmunotherapy for metastatic prostate cancer.

DeNardo SJ, Richman CM, Albrecht H, Burke PA, Natarajan A, Yuan A, Gregg JP, O'Donnell RT, DeNardo GL.

Clin Cancer Res. 2005 Oct 1;11(19 Pt 2):7187s-7194s.


Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice.

Wurz GT, Read KC, Marchisano-Karpman C, Gregg JP, Beckett LA, Yu Q, Degregorio MW.

J Steroid Biochem Mol Biol. 2005 Nov;97(3):230-40. Epub 2005 Sep 8.


Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior.

Borowsky AD, Namba R, Young LJ, Hunter KW, Hodgson JG, Tepper CG, McGoldrick ET, Muller WJ, Cardiff RD, Gregg JP.

Clin Exp Metastasis. 2005;22(1):47-59.


Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells.

Tepper CG, Gregg JP, Shi XB, Vinall RL, Baron CA, Ryan PE, Desprez PY, Kung HJ, deVere White RW.

Prostate. 2005 Dec 1;65(4):375-89.


Detecting the C282Y and H63D mutations of the HFE gene by Holliday Junction-based allele-specific genotyping methods.

Yang W, Yaoi T, Huang S, Yang Q, Hatcher S, Seet H, Gregg JP.

Clin Chem. 2005 Jan;51(1):210-3. No abstract available.


Molecular characterization of uterine fibroids and its implication for underlying mechanisms of pathogenesis.

Hoffman PJ, Milliken DB, Gregg LC, Davis RR, Gregg JP.

Fertil Steril. 2004 Sep;82(3):639-49.


Molecular characterization of the transition to malignancy in a genetically engineered mouse-based model of ductal carcinoma in situ.

Namba R, Maglione JE, Young LJ, Borowsky AD, Cardiff RD, MacLeod CL, Gregg JP.

Mol Cancer Res. 2004 Aug;2(8):453-63.


Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes.

Maglione JE, McGoldrick ET, Young LJ, Namba R, Gregg JP, Liu L, Moghanaki D, Ellies LG, Borowsky AD, Cardiff RD, MacLeod CL.

Mol Cancer Ther. 2004 Aug;3(8):941-53.


In vivo positron-emission tomography imaging of progression and transformation in a mouse model of mammary neoplasia.

Abbey CK, Borowsky AD, McGoldrick ET, Gregg JP, Maglione JE, Cardiff RD, Cherry SR.

Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11438-43. Epub 2004 Jul 26.

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