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Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation.

Gößwein S, Lindemann A, Mahajan A, Maueröder C, Martini E, Patankar J, Schett G, Becker C, Wirtz S, Naumann-Bartsch N, Bianchi ME, Greer PA, Lochnit G, Herrmann M, Neurath MF, Leppkes M.

Front Immunol. 2019 Oct 22;10:2481. doi: 10.3389/fimmu.2019.02481. eCollection 2019.


Bulk Anatomical Density Based Dose Calculation for Patient-Specific Quality Assurance of MRI-Only Prostate Radiotherapy.

Choi JH, Lee D, O'Connor L, Chalup S, Welsh JS, Dowling J, Greer PB.

Front Oncol. 2019 Oct 2;9:997. doi: 10.3389/fonc.2019.00997. eCollection 2019.


Becoming a Principal Investigator: Designing and Navigating Your Academic Adventure.

Greer PL, Samuel MA.

Neuron. 2019 Sep 25;103(6):959-963. doi: 10.1016/j.neuron.2019.08.023.


A Multi-center Prospective Study for Implementation of an MRI-Only Prostate Treatment Planning Workflow.

Greer P, Martin J, Sidhom M, Hunter P, Pichler P, Choi JH, Best L, Smart J, Young T, Jameson M, Afinidad T, Wratten C, Denham J, Holloway L, Sridharan S, Rai R, Liney G, Raniga P, Dowling J.

Front Oncol. 2019 Aug 29;9:826. doi: 10.3389/fonc.2019.00826. eCollection 2019.


Investigation of a Novel Decision Support Metric for Head and Neck Adaptive Radiation Therapy Using a Real-Time In Vivo Portal Dosimetry System.

Lim SB, Tsai CJ, Yu Y, Greer P, Fuangrod T, Hwang K, Fontenla S, Coffman F, Lee N, Lovelock DM.

Technol Cancer Res Treat. 2019 Jan 1;18:1533033819873629. doi: 10.1177/1533033819873629.


A PRMT5-RNF168-SMURF2 Axis Controls H2AX Proteostasis.

Du C, Hansen LJ, Singh SX, Wang F, Sun R, Moure CJ, Roso K, Greer PK, Yan H, He Y.

Cell Rep. 2019 Sep 17;28(12):3199-3211.e5. doi: 10.1016/j.celrep.2019.08.031.


Comparison of Deep Learning-Based and Patch-Based Methods for Pseudo-CT Generation in MRI-Based Prostate Dose Planning.

Largent A, Barateau A, Nunes JC, Mylona E, Castelli J, Lafond C, Greer PB, Dowling JA, Baxter J, Saint-Jalmes H, Acosta O, de Crevoisier R.

Int J Radiat Oncol Biol Phys. 2019 Sep 7. pii: S0360-3016(19)33735-6. doi: 10.1016/j.ijrobp.2019.08.049. [Epub ahead of print]


The accuracy and precision of the KIM motion monitoring system used in the multi-institutional TROG 15.01 Stereotactic Prostate Ablative Radiotherapy with KIM (SPARK) trial.

Hewson EA, Nguyen DT, O'Brien R, Kim JH, Montanaro T, Moodie T, Greer PB, Hardcastle N, Eade T, Kneebone A, Hruby G, Hayden AJ, Turner S, Siva S, Tai KH, Hunter P, Sams J, Poulsen PR, Booth JT, Martin J, Keall PJ.

Med Phys. 2019 Nov;46(11):4725-4737. doi: 10.1002/mp.13784. Epub 2019 Sep 20.


TROG 18.01 phase III randomised clinical trial of the Novel Integration of New prostate radiation schedules with adJuvant Androgen deprivation: NINJA study protocol.

Martin J, Keall P, Siva S, Greer P, Christie D, Moore K, Dowling J, Pryor D, Chong P, McLeod N, Raman A, Lynam J, Smart J, Oldmeadow C, Tang CI, Murphy DG, Millar J, Tai KH, Holloway L, Reeves P, Hayden A, Lim T, Holt T, Sidhom M.

BMJ Open. 2019 Aug 20;9(8):e030731. doi: 10.1136/bmjopen-2019-030731.


Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus.

Goodarzi MO, Nagpal T, Greer P, Cui J, Chen YI, Guo X, Pankow JS, Rotter JI, Alkaade S, Amann ST, Baillie J, Banks PA, Brand RE, Conwell DL, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, LaRusch J, Lewis MD, Money ME, Muniraj T, Papachristou GI, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Wilcox CM, Pandol SJ, Park WG, Andersen DK, Bellin MD, Hart PA, Yadav D, Whitcomb DC; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC).

Clin Transl Gastroenterol. 2019 Jul;10(7):e00057. doi: 10.14309/ctg.0000000000000057.


Supervised risk predictor of central gland lesions in prostate cancer using 1 H MR spectroscopic imaging with gradient offset-independent adiabaticity pulses.

Gholizadeh N, Greer PB, Simpson J, Fu C, Al-Iedani O, Lau P, Heerschap A, Ramadan S.

J Magn Reson Imaging. 2019 May 27. doi: 10.1002/jmri.26803. [Epub ahead of print]


Reactive Oxygen Species-Dependent Calpain Activation Contributes to Airway and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease.

Zhu J, Kovacs L, Han W, Liu G, Huo Y, Lucas R, Fulton D, Greer PA, Su Y.

Antioxid Redox Signal. 2019 Oct 20;31(12):804-818. doi: 10.1089/ars.2018.7648. Epub 2019 Jun 24.


Assessment of the accuracy of truebeam intrafraction motion review (IMR) system for prostate treatment guidance.

Kaur G, Lehmann J, Greer P, Simpson J.

Australas Phys Eng Sci Med. 2019 Jun;42(2):585-598. doi: 10.1007/s13246-019-00760-7. Epub 2019 May 13.


Sporadic Genetic Connectivity among Small Insular Populations of the Rare Geoendemic Plant Caulanthus amplexicaulis var. barbarae (Santa Barbara Jewelflower).

Burrell AM, Goddard JHR, Greer PJ, Williams RJ, Pepper AE.

J Hered. 2019 Aug 16;110(5):587-600. doi: 10.1093/jhered/esz029.


MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation.

Hansen LJ, Sun R, Yang R, Singh SX, Chen LH, Pirozzi CJ, Moure CJ, Hemphill C, Carpenter AB, Healy P, Ruger RC, Chen CJ, Greer PK, Zhao F, Spasojevic I, Grenier C, Huang Z, Murphy SK, McLendon RE, Friedman HS, Friedman AH, Herndon JE 2nd, Sampson JH, Keir ST, Bigner DD, Yan H, He Y.

Cancer Res. 2019 Jul 1;79(13):3383-3394. doi: 10.1158/0008-5472.CAN-18-1010. Epub 2019 Apr 30.


Phase 2 Multicenter Study of Gantry-Based Stereotactic Radiotherapy Boost for Intermediate and High Risk Prostate Cancer (PROMETHEUS).

Pryor D, Sidhom M, Arumugam S, Bucci J, Gallagher S, Smart J, Grand M, Greer P, Keats S, Wilton L, Martin J.

Front Oncol. 2019 Apr 2;9:217. doi: 10.3389/fonc.2019.00217. eCollection 2019.


Similarity clustering-based atlas selection for pelvic CT image segmentation.

Kennedy A, Dowling J, Greer PB, Holloway L, Jameson MG, Roach D, Ghose S, Rivest-Hénault D, Marcello M, Ebert MA.

Med Phys. 2019 May;46(5):2243-2250. doi: 10.1002/mp.13494. Epub 2019 Apr 22.


Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe.

Liu Y, Carpenter AB, Pirozzi CJ, Yuan H, Waitkus MS, Zhou Z, Hansen L, Seywald M, Odion R, Greer PK, Hawk T, Chin BB, Vaidyanathan G, Zalutsky MR, Yan H, Vo-Dinh T.

Nanotechnology. 2019 Jul 5;30(27):275101. doi: 10.1088/1361-6528/ab0e9c. Epub 2019 Mar 11.


Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis.

Teng X, Ji C, Zhong H, Zheng D, Ni R, Hill DJ, Xiong S, Fan GC, Greer PA, Shen Z, Peng T.

Diabetologia. 2019 May;62(5):860-872. doi: 10.1007/s00125-019-4828-y. Epub 2019 Feb 18.


Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer.

Ghaffari A, Hoskin V, Turashvili G, Varma S, Mewburn J, Mullins G, Greer PA, Kiefer F, Day AG, Madarnas Y, SenGupta S, Elliott BE.

Breast Cancer Res. 2019 Jan 24;21(1):12. doi: 10.1186/s13058-018-1079-7.


An inter-centre statistical scale standardisation for quantitatively evaluating prostate tissue on T2-weighted MRI.

Gholizadeh N, Fuangrod T, Greer PB, Lau P, Ramadan S, Simpson J.

Australas Phys Eng Sci Med. 2019 Mar;42(1):137-147. doi: 10.1007/s13246-019-00720-1. Epub 2019 Jan 14.


Genetic Models of Calpain Deficiency and Ectopic Expression.

Gao Y, Hall C, MacLeod J, Greer PA.

Methods Mol Biol. 2019;1915:261-274. doi: 10.1007/978-1-4939-8988-1_20.


Multi-observer contouring of male pelvic anatomy: Highly variable agreement across conventional and emerging structures of interest.

Roach D, Holloway LC, Jameson MG, Dowling JA, Kennedy A, Greer PB, Krawiec M, Rai R, Denham J, De Leon J, Lim K, Berry ME, White RT, Bydder SA, Tan HT, Croker JD, McGrath A, Matthews J, Smeenk RJ, Ebert MA.

J Med Imaging Radiat Oncol. 2019 Apr;63(2):264-271. doi: 10.1111/1754-9485.12844. Epub 2019 Jan 4.


Characterization of prostate cancer using diffusion tensor imaging: A new perspective.

Gholizadeh N, Greer PB, Simpson J, Denham J, Lau P, Dowling J, Hondermarck H, Ramadan S.

Eur J Radiol. 2019 Jan;110:112-120. doi: 10.1016/j.ejrad.2018.11.026. Epub 2018 Nov 22.


Remote dosimetric auditing of clinical trials: The need for vendor specific models to convert images to dose.

Miri N, Vial P, Greer PB.

J Appl Clin Med Phys. 2019 Jan;20(1):175-183. doi: 10.1002/acm2.12521. Epub 2018 Dec 31.


Association of Dietary Habits with Severity of Acute Pancreatitis.

Dugum M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I, O'Keefe SJD, Whitcomb DC, Yadav D, Papachristou GI.

Curr Dev Nutr. 2018 Oct 8;2(12):nzy075. doi: 10.1093/cdn/nzy075. eCollection 2018 Dec.


Pseudo-CT Generation for MRI-Only Radiation Therapy Treatment Planning: Comparison Among Patch-Based, Atlas-Based, and Bulk Density Methods.

Largent A, Barateau A, Nunes JC, Lafond C, Greer PB, Dowling JA, Saint-Jalmes H, Acosta O, de Crevoisier R.

Int J Radiat Oncol Biol Phys. 2019 Feb 1;103(2):479-490. doi: 10.1016/j.ijrobp.2018.10.002. Epub 2018 Oct 16.


Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib.

MacLeod JA, Gao Y, Hall C, Muller WJ, Gujral TS, Greer PA.

Oncotarget. 2018 Sep 7;9(70):33382-33395. doi: 10.18632/oncotarget.26078. eCollection 2018 Sep 7.


A remote EPID-based dosimetric TPS-planned audit of centers for clinical trials: outcomes and analysis of contributing factors.

Miri N, Legge K, Colyvas K, Lehmann J, Vial P, Moore A, Harris M, Greer PB.

Radiat Oncol. 2018 Sep 17;13(1):178. doi: 10.1186/s13014-018-1125-8.


Comparative study of algorithms for synthetic CT generation from MRI: Consequences for MRI-guided radiation planning in the pelvic region.

Arabi H, Dowling JA, Burgos N, Han X, Greer PB, Koutsouvelis N, Zaidi H.

Med Phys. 2018 Nov;45(11):5218-5233. doi: 10.1002/mp.13187. Epub 2018 Oct 10.


Evaluation of the truebeam machine performance check (MPC): OBI X-ray tube alignment procedure.

Barnes MP, Pomare D, Menk FW, Moraro B, Greer PB.

J Appl Clin Med Phys. 2018 Nov;19(6):68-78. doi: 10.1002/acm2.12445. Epub 2018 Sep 3.


Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells.

Lei K, Sun R, Chen LH, Diplas BH, Moure CJ, Wang W, Hansen LJ, Tao Y, Chen X, Chen CJ, Greer PK, Zhao F, Yan H, Bigner DD, Huang J, He Y.

Sci Rep. 2018 Aug 21;8(1):12507. doi: 10.1038/s41598-018-30062-z.


Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts.

Zhan W, Shelton CA, Greer PJ, Brand RE, Whitcomb DC.

Pancreas. 2018 Sep;47(8):924-936. doi: 10.1097/MPA.0000000000001136.


Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients.

Greer JB, Greer P, Sandhu BS, Alkaade S, Wilcox CM, Anderson MA, Sherman S, Gardner TB, Lewis MD, Guda NM, Muniraj T, Conwell D, Cote GA, Forsmark CE, Banks PA, Tang G, Stello K, Gelrud A, Brand RE, Slivka A, Whitcomb DC, Yadav D.

Nutr Clin Pract. 2019 Jun;34(3):387-399. doi: 10.1002/ncp.10186. Epub 2018 Aug 13.


A proposed method for linear accelerator photon beam steering using EPID.

Barnes MP, Menk FW, Lamichhane BP, Greer PB.

J Appl Clin Med Phys. 2018 Sep;19(5):591-597. doi: 10.1002/acm2.12419. Epub 2018 Jul 26.


Estimation of Hounsfield unit conversion parameters for pelvic CT images.

Kennedy A, Dowling J, Greer PB, Ebert MA.

Australas Phys Eng Sci Med. 2018 Sep;41(3):739-745. doi: 10.1007/s13246-018-0651-x. Epub 2018 Jun 7.


Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African ancestry.

Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb DC, Yadav D.

Pancreatology. 2018 May 19. pii: S1424-3903(18)30588-X. doi: 10.1016/j.pan.2018.05.482. [Epub ahead of print]


In Reply to Kim.

Greer PJ Jr, Brown DR, Brewster LG Jr.

Acad Med. 2018 Jun;93(6):817-818. doi: 10.1097/ACM.0000000000002224. No abstract available.


The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.

Diplas BH, He X, Brosnan-Cashman JA, Liu H, Chen LH, Wang Z, Moure CJ, Killela PJ, Loriaux DB, Lipp ES, Greer PK, Yang R, Rizzo AJ, Rodriguez FJ, Friedman AH, Friedman HS, Wang S, He Y, McLendon RE, Bigner DD, Jiao Y, Waitkus MS, Meeker AK, Yan H.

Nat Commun. 2018 May 25;9(1):2087. doi: 10.1038/s41467-018-04448-6.


Electromagnetic-Guided MLC Tracking Radiation Therapy for Prostate Cancer Patients: Prospective Clinical Trial Results.

Keall PJ, Colvill E, O'Brien R, Caillet V, Eade T, Kneebone A, Hruby G, Poulsen PR, Zwan B, Greer PB, Booth J.

Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):387-395. doi: 10.1016/j.ijrobp.2018.01.098. Epub 2018 Feb 6.


Feasibility study on 3D image reconstruction from 2D orthogonal cine-MRI for MRI-guided radiotherapy.

Paganelli C, Lee D, Kipritidis J, Whelan B, Greer PB, Baroni G, Riboldi M, Keall P.

J Med Imaging Radiat Oncol. 2018 Jun;62(3):389-400. doi: 10.1111/1754-9485.12713. Epub 2018 Feb 11.


MRI-only treatment planning: benefits and challenges.

Owrangi AM, Greer PB, Glide-Hurst CK.

Phys Med Biol. 2018 Feb 26;63(5):05TR01. doi: 10.1088/1361-6560/aaaca4. Review.


Audiovisual biofeedback improves the correlation between internal/external surrogate motion and lung tumor motion.

Lee D, Greer PB, Paganelli C, Ludbrook JJ, Kim T, Keall P.

Med Phys. 2018 Mar;45(3):1009-1017. doi: 10.1002/mp.12758. Epub 2018 Feb 19.


Correlations between contouring similarity metrics and simulated treatment outcome for prostate radiotherapy.

Roach D, Jameson MG, Dowling JA, Ebert MA, Greer PB, Kennedy AM, Watt S, Holloway LC.

Phys Med Biol. 2018 Jan 22;63(3):035001. doi: 10.1088/1361-6560/aaa50c.


Wool-derived keratin hydrogel enhances implant osseointegration in cancellous bone.

Duncan WJ, Greer PFC, Lee MH, Loch C, Gay JHA.

J Biomed Mater Res B Appl Biomater. 2018 Aug;106(6):2447-2454. doi: 10.1002/jbm.b.34047. Epub 2017 Dec 11.


Audiovisual biofeedback guided breath-hold improves lung tumor position reproducibility and volume consistency.

Lee D, Greer PB, Lapuz C, Ludbrook J, Hunter P, Arm J, Pollock S, Makhija K, O'Brien RT, Kim T, Keall P.

Adv Radiat Oncol. 2017 Mar 10;2(3):354-362. doi: 10.1016/j.adro.2017.03.002. eCollection 2017 Jul-Sep.


Combined targeting of Raf and Mek synergistically inhibits tumorigenesis in triple negative breast cancer model systems.

Nagaria TS, Shi C, Leduc C, Hoskin V, Sikdar S, Sangrar W, Greer PA.

Oncotarget. 2017 Aug 24;8(46):80804-80819. doi: 10.18632/oncotarget.20534. eCollection 2017 Oct 6.


Inhibition of angiotensin II and calpain attenuates pleural fibrosis.

Song LJ, Xiang F, Ye H, Huang H, Yang J, Yu F, Xiong L, Xu JJ, Greer PA, Shi HZ, Xin JB, Su Y, Ma WL.

Pulm Pharmacol Ther. 2018 Feb;48:46-52. doi: 10.1016/j.pupt.2017.10.012. Epub 2017 Nov 4.


An easy-to-use FRET protein substrate to detect calpain cleavage in vitro and in vivo.

McCartney CE, MacLeod JA, Greer PA, Davies PL.

Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):221-230. doi: 10.1016/j.bbamcr.2017.10.013. Epub 2017 Nov 14.


A virtual dosimetry audit - Towards transferability of gamma index analysis between clinical trial QA groups.

Hussein M, Clementel E, Eaton DJ, Greer PB, Haworth A, Ishikura S, Kry SF, Lehmann J, Lye J, Monti AF, Nakamura M, Hurkmans C, Clark CH; Global Quality Assurance of Radiation Therapy Clinical Trial Harmonisation Group.

Radiother Oncol. 2017 Dec;125(3):398-404. doi: 10.1016/j.radonc.2017.10.012.


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