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A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.

Wong C, Chen F, Alirezaie N, Wang Y, Cuggia A, Borgida A, Holter S, Lenko T, Domecq C; Alzheimer’s Disease Neuroimaging Initiative, Petersen GM, Syngal S, Brand R, Rustgi AK, Cote ML, Stoffel E, Olson SH, Roberts NJ, Akbari MR, Majewski J, Klein AP, Greenwood CMT, Gallinger S, Zogopoulos G.

PLoS Genet. 2019 Aug 30;15(8):e1008344. doi: 10.1371/journal.pgen.1008344. eCollection 2019 Aug.


Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing.

Shao X, Hudson M, Colmegna I, Greenwood CMT, Fritzler MJ, Awadalla P, Pastinen T, Bernatsky S.

Clin Epigenetics. 2019 Jul 31;11(1):110. doi: 10.1186/s13148-019-0699-9.


Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells.

Ghashghaei M, Niazi TM, Aguilar-Mahecha A, Klein KO, Greenwood CMT, Basik M, Muanza TM.

Sci Rep. 2019 Jun 20;9(1):8838. doi: 10.1038/s41598-019-44991-w.


General psychopathology, internalising and externalising in children and functional outcomes in late adolescence.

Sallis H, Szekely E, Neumann A, Jolicoeur-Martineau A, van IJzendoorn M, Hillegers M, Greenwood CMT, Meaney MJ, Steiner M, Tiemeier H, Wazana A, Pearson RM, Evans J.

J Child Psychol Psychiatry. 2019 May 2. doi: 10.1111/jcpp.13067. [Epub ahead of print]


Constrained instruments and their application to Mendelian randomization with pleiotropy.

Jiang L, Oualkacha K, Didelez V, Ciampi A, Rosa-Neto P, Benedet AL, Mathotaarachchi S, Richards JB, Greenwood CMT; Alzheimer’s Disease Neuroimaging Initiative.

Genet Epidemiol. 2019 Jun;43(4):373-401. doi: 10.1002/gepi.22184. Epub 2019 Jan 12.


Integration of "omics" Data and Phenotypic Data Within a Unified Extensible Multimodal Framework.

Das S, Lecours Boucher X, Rogers C, Makowski C, Chouinard-Decorte F, Oros Klein K, Beck N, Rioux P, Brown ST, Mohaddes Z, Zweber C, Foing V, Forest M, O'Donnell KJ, Clark J, Meaney MJ, Greenwood CMT, Evans AC.

Front Neuroinform. 2018 Dec 18;12:91. doi: 10.3389/fninf.2018.00091. eCollection 2018.


Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Manousaki D, Dudding T, Haworth S, Hsu YH, Liu CT, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Ikram MA, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, de Groot LCPGM, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards JB.

Am J Hum Genet. 2018 Dec 6;103(6):1053. doi: 10.1016/j.ajhg.2018.11.010. No abstract available.


Investigating potential causal relationships between SNPs, DNA methylation and HDL.

Jiang L, Zhao K, Klein K, Canty AJ, Oualkacha K, Greenwood CMT.

BMC Proc. 2018 Sep 17;12(Suppl 9):20. doi: 10.1186/s12919-018-0117-x. eCollection 2018.


CpG-set association assessment of lipid concentration changes and DNA methylation.

Zhao K, Jiang L, Klein K, Greenwood CMT, Oualkacha K.

BMC Proc. 2018 Sep 17;12(Suppl 9):30. doi: 10.1186/s12919-018-0127-8. eCollection 2018.


A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data.

Shokoohi F, Stephens DA, Bourque G, Pastinen T, Greenwood CMT, Labbe A.

Biometrics. 2019 Mar;75(1):210-221. doi: 10.1111/biom.12965. Epub 2018 Oct 9.


SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

Findlay S, Heath J, Luo VM, Malina A, Morin T, Coulombe Y, Djerir B, Li Z, Samiei A, Simo-Cheyou E, Karam M, Bagci H, Rahat D, Grapton D, Lavoie EG, Dove C, Khaled H, Kuasne H, Mann KK, Klein KO, Greenwood CM, Tabach Y, Park M, Côté JF, Masson JY, Maréchal A, Orthwein A.

EMBO J. 2018 Sep 14;37(18). pii: e100158. doi: 10.15252/embj.2018100158. Epub 2018 Aug 28.


Alternating optimization for G × E modelling with weighted genetic and environmental scores: Examples from the MAVAN study.

Jolicoeur-Martineau A, Wazana A, Szekely E, Steiner M, Fleming AS, Kennedy JL, Meaney MJ, Greenwood CMT.

Psychol Methods. 2019 Apr;24(2):196-216. doi: 10.1037/met0000175. Epub 2018 Aug 13.


PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores.

Chen LM, Yao N, Garg E, Zhu Y, Nguyen TTT, Pokhvisneva I, Hari Dass SA, Unternaehrer E, Gaudreau H, Forest M, McEwen LM, MacIsaac JL, Kobor MS, Greenwood CMT, Silveira PP, Meaney MJ, O'Donnell KJ.

BMC Bioinformatics. 2018 Aug 8;19(1):295. doi: 10.1186/s12859-018-2289-9.


X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells.

Ho B, Greenlaw K, Al Tuwaijri A, Moussette S, Martínez F, Giorgio E, Brusco A, Ferrero GB, Linhares ND, Valadares ER, Svartman M, Kalscheuer VM, Rodríguez Criado G, Laprise C, Greenwood CMT, Naumova AK.

Biol Sex Differ. 2018 Feb 20;9(1):10. doi: 10.1186/s13293-018-0169-7.


Heritable contributions versus genetic architecture.

Timpson NJ, Greenwood CMT, Soranzo N, Lawson DJ, Richards JB.

Nat Rev Genet. 2018 Feb 14;19(3):185. doi: 10.1038/nrg.2018.7. No abstract available.


An analytic approach for interpretable predictive models in high-dimensional data in the presence of interactions with exposures.

Bhatnagar SR, Yang Y, Khundrakpam B, Evans AC, Blanchette M, Bouchard L, Greenwood CMT.

Genet Epidemiol. 2018 Apr;42(3):233-249. doi: 10.1002/gepi.22112. Epub 2018 Feb 8.


Distinct homologous recombination gene expression profiles after neoadjuvant chemotherapy associated with clinical outcome in patients with ovarian cancer.

Kessous R, Octeau D, Klein K, Tonin PN, Greenwood CMT, Pelmus M, Laskov I, Kogan L, Salvador S, Lau S, Yasmeen A, Gotlieb WH.

Gynecol Oncol. 2018 Mar;148(3):553-558. doi: 10.1016/j.ygyno.2018.01.017. Epub 2018 Feb 1.


Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time.

Forest M, O'Donnell KJ, Voisin G, Gaudreau H, MacIsaac JL, McEwen LM, Silveira PP, Steiner M, Kobor MS, Meaney MJ, Greenwood CMT.

Epigenetics. 2018;13(1):19-32. doi: 10.1080/15592294.2017.1411443. Epub 2018 Jan 30.


Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation.

Sun J, Oualkacha K, Forgetta V, Zheng HF, Richards JB, Evans DS, Orwoll E, Greenwood CMT.

Sci Rep. 2018 Jan 9;8(1):220. doi: 10.1038/s41598-017-18385-9.


EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner.

Arabzadeh A, McGregor K, Breton V, Van Der Kraak L, Akavia UD, Greenwood CMT, Beauchemin N.

Oncotarget. 2017 Nov 1;8(61):104330-104346. doi: 10.18632/oncotarget.22236. eCollection 2017 Nov 28.


Genetic architecture: the shape of the genetic contribution to human traits and disease.

Timpson NJ, Greenwood CMT, Soranzo N, Lawson DJ, Richards JB.

Nat Rev Genet. 2018 Feb;19(2):110-124. doi: 10.1038/nrg.2017.101. Epub 2017 Dec 11. Review.


Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.

Cruceanu C, Schmouth JF, Torres-Platas SG, Lopez JP, Ambalavanan A, Darcq E, Gross F, Breton B, Spiegelman D, Rochefort D, Hince P, Petite JM, Gauthier J, Lafrenière RG, Dion PA, Greenwood CM, Kieffer BL, Alda M, Turecki G, Rouleau GA.

Mol Psychiatry. 2018 Oct;23(10):2050-2056. doi: 10.1038/mp.2017.223. Epub 2017 Nov 21.


A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type.

Lakhal-Chaieb L, Greenwood CMT, Ouhourane M, Zhao K, Abdous B, Oualkacha K.

Stat Appl Genet Mol Biol. 2017 Nov 27;16(5-6):333-347. doi: 10.1515/sagmb-2016-0062.


Model-Free Linkage Analysis of a Binary Trait.

Xu W, Ma J, Greenwood CMT, Paterson AD, Bull SB.

Methods Mol Biol. 2017;1666:343-373. doi: 10.1007/978-1-4939-7274-6_17.


The performance of a new local false discovery rate method on tests of association between coronary artery disease (CAD) and genome-wide genetic variants.

Mei S, Karimnezhad A, Forest M, Bickel DR, Greenwood CMT.

PLoS One. 2017 Sep 20;12(9):e0185174. doi: 10.1371/journal.pone.0185174. eCollection 2017.


Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.

Kemp JP, Morris JA, Medina-Gomez C, Forgetta V, Warrington NM, Youlten SE, Zheng J, Gregson CL, Grundberg E, Trajanoska K, Logan JG, Pollard AS, Sparkes PC, Ghirardello EJ, Allen R, Leitch VD, Butterfield NC, Komla-Ebri D, Adoum AT, Curry KF, White JK, Kussy F, Greenlaw KM, Xu C, Harvey NC, Cooper C, Adams DJ, Greenwood CMT, Maurano MT, Kaptoge S, Rivadeneira F, Tobias JH, Croucher PI, Ackert-Bicknell CL, Bassett JHD, Williams GR, Richards JB, Evans DM.

Nat Genet. 2017 Oct;49(10):1468-1475. doi: 10.1038/ng.3949. Epub 2017 Sep 4.


Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Manousaki D, Dudding T, Haworth S, Hsu YH, Liu CT, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Ikram MA, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, de Groot LCPGM, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards JB.

Am J Hum Genet. 2017 Aug 3;101(2):227-238. doi: 10.1016/j.ajhg.2017.06.014. Epub 2017 Jul 27. Erratum in: Am J Hum Genet. 2018 Dec 6;103(6):1053.


Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.

Tachmazidou I, Süveges D, Min JL, Ritchie GRS, Steinberg J, Walter K, Iotchkova V, Schwartzentruber J, Huang J, Memari Y, McCarthy S, Crawford AA, Bombieri C, Cocca M, Farmaki AE, Gaunt TR, Jousilahti P, Kooijman MN, Lehne B, Malerba G, Männistö S, Matchan A, Medina-Gomez C, Metrustry SJ, Nag A, Ntalla I, Paternoster L, Rayner NW, Sala C, Scott WR, Shihab HA, Southam L, St Pourcain B, Traglia M, Trajanoska K, Zaza G, Zhang W, Artigas MS, Bansal N, Benn M, Chen Z, Danecek P, Lin WY, Locke A, Luan J, Manning AK, Mulas A, Sidore C, Tybjaerg-Hansen A, Varbo A, Zoledziewska M, Finan C, Hatzikotoulas K, Hendricks AE, Kemp JP, Moayyeri A, Panoutsopoulou K, Szpak M, Wilson SG, Boehnke M, Cucca F, Di Angelantonio E, Langenberg C, Lindgren C, McCarthy MI, Morris AP, Nordestgaard BG, Scott RA, Tobin MD, Wareham NJ; SpiroMeta Consortium; GoT2D Consortium, Burton P, Chambers JC, Smith GD, Dedoussis G, Felix JF, Franco OH, Gambaro G, Gasparini P, Hammond CJ, Hofman A, Jaddoe VWV, Kleber M, Kooner JS, Perola M, Relton C, Ring SM, Rivadeneira F, Salomaa V, Spector TD, Stegle O, Toniolo D, Uitterlinden AG; arcOGEN Consortium; Understanding Society Scientific Group; UK10K Consortium, Barroso I, Greenwood CMT, Perry JRB, Walker BR, Butterworth AS, Xue Y, Durbin R, Small KS, Soranzo N, Timpson NJ, Zeggini E.

Am J Hum Genet. 2017 Jun 1;100(6):865-884. doi: 10.1016/j.ajhg.2017.04.014. Epub 2017 May 25.


A Set-Based Mixed Effect Model for Gene-Environment Interaction and Its Application to Neuroimaging Phenotypes.

Wang C, Sun J, Guillaume B, Ge T, Hibar DP, Greenwood CMT, Qiu A; Alzheimer's Disease Neuroimaging Initiative.

Front Neurosci. 2017 Apr 6;11:191. doi: 10.3389/fnins.2017.00191. eCollection 2017.


Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis.

Hudson M, Bernatsky S, Colmegna I, Lora M, Pastinen T, Klein Oros K, Greenwood CMT.

Epigenetics. 2017 Jun 3;12(6):433-440. doi: 10.1080/15592294.2017.1303581. Epub 2017 Apr 7.


Gene networks show associations with seed region connectivity.

Forest M, Iturria-Medina Y, Goldman JS, Kleinman CL, Lovato A, Oros Klein K, Evans A, Ciampi A, Labbe A, Greenwood CMT.

Hum Brain Mapp. 2017 Jun;38(6):3126-3140. doi: 10.1002/hbm.23579. Epub 2017 Mar 21.


Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation.

Chan D, McGraw S, Klein K, Wallock LM, Konermann C, Plass C, Chan P, Robaire B, Jacob RA, Greenwood CM, Trasler JM.

Hum Reprod. 2017 Feb;32(2):272-283. doi: 10.1093/humrep/dew308. Epub 2016 Dec 18.


Joint analysis of multiple blood pressure phenotypes in GAW19 data by using a multivariate rare-variant association test.

Sun J, Bhatnagar SR, Oualkacha K, Ciampi A, Greenwood CM.

BMC Proc. 2016 Oct 18;10(Suppl 7):309-313. eCollection 2016.


Assessing transmission ratio distortion in extended families: a comparison of analysis methods.

Bhatnagar SR, Greenwood CM, Labbe A.

BMC Proc. 2016 Oct 18;10(Suppl 7):197-202. eCollection 2016.


Genetic Analysis Workshop 19: methods and strategies for analyzing human sequence and gene expression data in extended families and unrelated individuals.

Engelman CD, Greenwood CM, Bailey JN, Cantor RM, Kent JW Jr, König IR, Bermejo JL, Melton PE, Santorico SA, Schillert A, Wijsman EM, MacCluer JW, Almasy L.

BMC Proc. 2016 Oct 18;10(Suppl 7):67-70. eCollection 2016.


The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.

van Kempen LC, Redpath M, Elchebly M, Klein KO, Papadakis AI, Wilmott JS, Scolyer RA, Edqvist PH, Pontén F, Schadendorf D, van Rijk AF, Michiels S, Dumay A, Helbling-Leclerc A, Dessen P, Wouters J, Stass M, Greenwood CM, Ghanem GE, van den Oord J, Feunteun J, Spatz A.

Sci Transl Med. 2016 Dec 14;8(369):369ra177.


Toward Precision Medicine: TBC1D4 Disruption Is Common Among the Inuit and Leads to Underdiagnosis of Type 2 Diabetes.

Manousaki D, Kent JW Jr, Haack K, Zhou S, Xie P, Greenwood CM, Brassard P, Newman DE, Cole S, Umans JG, Rouleau G, Comuzzie AG, Richards JB.

Diabetes Care. 2016 Nov;39(11):1889-1895. Epub 2016 Aug 25.


Gene Coexpression Analyses Differentiate Networks Associated with Diverse Cancers Harboring TP53 Missense or Null Mutations.

Oros Klein K, Oualkacha K, Lafond MH, Bhatnagar S, Tonin PN, Greenwood CM.

Front Genet. 2016 Aug 3;7:137. doi: 10.3389/fgene.2016.00137. eCollection 2016.


Principal component of explained variance: An efficient and optimal data dimension reduction framework for association studies.

Turgeon M, Oualkacha K, Ciampi A, Miftah H, Dehghan G, Zanke BW, Benedet AL, Rosa-Neto P, Greenwood CM, Labbe A; Alzheimer’s Disease Neuroimaging Initiative.

Stat Methods Med Res. 2018 May;27(5):1331-1350. doi: 10.1177/0962280216660128. Epub 2016 Jul 26.


Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma.

Assouline SE, Nielsen TH, Yu S, Alcaide M, Chong L, MacDonald D, Tosikyan A, Kukreti V, Kezouh A, Petrogiannis-Haliotis T, Albuquerque M, Fornika D, Alamouti S, Froment R, Greenwood CM, Oros KK, Camglioglu E, Sharma A, Christodoulopoulos R, Rousseau C, Johnson N, Crump M, Morin RD, Mann KK.

Blood. 2016 Jul 14;128(2):185-94. doi: 10.1182/blood-2016-02-699520. Epub 2016 May 10.


An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies.

McGregor K, Bernatsky S, Colmegna I, Hudson M, Pastinen T, Labbe A, Greenwood CM.

Genome Biol. 2016 May 3;17:84. doi: 10.1186/s13059-016-0935-y.


Software Application Profile: RVPedigree: a suite of family-based rare variant association tests for normally and non-normally distributed quantitative traits.

Oualkacha K, Lakhal-Chaieb L, Greenwood CM.

Int J Epidemiol. 2016 Apr;45(2):402-7. doi: 10.1093/ije/dyw047. Epub 2016 Apr 16.


Correction: Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study.

Mokry LE, Ross S, Ahmad OS, Forgetta V, Smith GD, Goltzman D, Leong A, Greenwood CM, Thanassoulis G, Richards JB.

PLoS Med. 2016 Mar 2;13(3):e1001981. doi: 10.1371/journal.pmed.1001981. eCollection 2016 Mar. No abstract available.


Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors.

Rivera B, Gayden T, Carrot-Zhang J, Nadaf J, Boshari T, Faury D, Zeinieh M, Blanc R, Burk DL, Fahiminiya S, Bareke E, Schüller U, Monoranu CM, Sträter R, Kerl K, Niederstadt T, Kurlemann G, Ellezam B, Michalak Z, Thom M, Lockhart PJ, Leventer RJ, Ohm M, MacGregor D, Jones D, Karamchandani J, Greenwood CM, Berghuis AM, Bens S, Siebert R, Zakrzewska M, Liberski PP, Zakrzewski K, Sisodiya SM, Paulus W, Albrecht S, Hasselblatt M, Jabado N, Foulkes WD, Majewski J.

Acta Neuropathol. 2016 Jun;131(6):847-63. doi: 10.1007/s00401-016-1549-x. Epub 2016 Feb 26.


A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects.

Sun J, Oualkacha K, Forgetta V, Zheng HF, Brent Richards J, Ciampi A, Greenwood CM; UK10K Consortium.

Eur J Hum Genet. 2016 Aug;24(9):1344-51. doi: 10.1038/ejhg.2016.8. Epub 2016 Feb 10.


funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types.

Oros Klein K, Grinek S, Bernatsky S, Bouchard L, Ciampi A, Colmegna I, Fortin JP, Gao L, Hivert MF, Hudson M, Kobor MS, Labbe A, MacIsaac JL, Meaney MJ, Morin AM, O'Donnell KJ, Pastinen T, Van Ijzendoorn MH, Voisin G, Greenwood CM.

Bioinformatics. 2016 Feb 15;32(4):593-5. doi: 10.1093/bioinformatics/btv615. Epub 2015 Oct 24.


A rare variant association test in family-based designs and non-normal quantitative traits.

Lakhal-Chaieb L, Oualkacha K, Richards BJ, Greenwood CM.

Stat Med. 2016 Mar 15;35(6):905-21. doi: 10.1002/sim.6750. Epub 2015 Sep 29.


The UK10K project identifies rare variants in health and disease.

UK10K Consortium, Walter K, Min JL, Huang J, Crooks L, Memari Y, McCarthy S, Perry JR, Xu C, Futema M, Lawson D, Iotchkova V, Schiffels S, Hendricks AE, Danecek P, Li R, Floyd J, Wain LV, Barroso I, Humphries SE, Hurles ME, Zeggini E, Barrett JC, Plagnol V, Richards JB, Greenwood CM, Timpson NJ, Durbin R, Soranzo N.

Nature. 2015 Oct 1;526(7571):82-90. doi: 10.1038/nature14962. Epub 2015 Sep 14.


Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gómez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LC, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellström D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren Ö, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussière J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Hermann AP, Jensen JE, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Åkesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G; AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Zillikens MC, van Meurs JB, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson K, Hinds DA, Spector T, Cupples LA, Ohlsson C, Greenwood CM; UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB.

Nature. 2015 Oct 1;526(7571):112-7. doi: 10.1038/nature14878. Epub 2015 Sep 14.

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