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Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science?

McGivern H, Greenwood C, Márquez-Grant N, Kranioti EF, Xhemali B, Zioupos P.

Front Bioeng Biotechnol. 2020 Jan 22;7:467. doi: 10.3389/fbioe.2019.00467. eCollection 2019.


Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes.

Lu T, Forgetta V, Yu OHY, Mokry L, Gregory M, Thanassoulis G, Greenwood CMT, Richards JB.

Cardiovasc Diabetol. 2020 Jan 30;19(1):12. doi: 10.1186/s12933-020-0988-9.


At the interface.

Greenwood CMT.

Genet Epidemiol. 2020 Mar;44(2):119-124. doi: 10.1002/gepi.22277. Epub 2020 Jan 10. No abstract available.


Enhancing the utility of the problem gambling severity index in clinical settings: Identifying refined categories within the problem gambling category.

Merkouris SS, Greenwood C, Manning V, Oakes J, Rodda S, Lubman D, Dowling NA.

Addict Behav. 2020 Apr;103:106257. doi: 10.1016/j.addbeh.2019.106257. Epub 2019 Dec 18.


A flexible copula-based approach for the analysis of secondary phenotypes in ascertained samples.

Tounkara F, Lefebvre G, Greenwood C, Oualkacha K.

Stat Med. 2020 Feb 28;39(5):517-543. doi: 10.1002/sim.8416. Epub 2019 Dec 23.


Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer.

Jeyakumar T, Fodil N, Van Der Kraak L, Meunier C, Cayrol R, McGregor K, Langlais D, Greenwood CMT, Beauchemin N, Gros P.

Sci Rep. 2019 Dec 11;9(1):18897. doi: 10.1038/s41598-019-55378-2.


Calcification Microstructure Reflects Breast Tissue Microenvironment.

Gosling S, Scott R, Greenwood C, Bouzy P, Nallala J, Lyburn ID, Stone N, Rogers K.

J Mammary Gland Biol Neoplasia. 2019 Dec;24(4):333-342. doi: 10.1007/s10911-019-09441-3. Epub 2019 Dec 5.


MDiNE: A model to estimate differential co-occurrence networks in microbiome studies.

McGregor K, Labbe A, Greenwood CMT.

Bioinformatics. 2019 Nov 7. pii: btz824. doi: 10.1093/bioinformatics/btz824. [Epub ahead of print]


Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis.

Lu T, Klein KO, Colmegna I, Lora M, Greenwood CMT, Hudson M.

BMC Med Genomics. 2019 Oct 24;12(1):144. doi: 10.1186/s12920-019-0602-8.


Suicidal ideation is common in autosomal dominant Alzheimer's disease at-risk persons.

Ng KP, Richard-Devantoy S, Bertrand JA, Jiang L, Pascoal TA, Mathotaarachchi S, Therriault J, Yatawara C, Kandiah N, Greenwood CMT, Rosa-Neto P, Gauthier S; Dominantly Inherited Alzheimer Network.

Int J Geriatr Psychiatry. 2020 Jan;35(1):60-68. doi: 10.1002/gps.5215. Epub 2019 Oct 22.


Outcome-Related Differences in Gene Expression Profiles of High-Grade Serous Ovarian Cancers Following Neoadjuvant Chemotherapy.

Octeau D, Kessous R, Klein K, Kogan L, Pelmus M, Ferenczy A, Greenwood CMT, Van Kempen LC, Salvador S, Lau S, Tonin PN, Yasmeen A, Gotlieb WH.

Mol Cancer Res. 2019 Dec;17(12):2422-2431. doi: 10.1158/1541-7786.MCR-19-0398. Epub 2019 Sep 17.


A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.

Wong C, Chen F, Alirezaie N, Wang Y, Cuggia A, Borgida A, Holter S, Lenko T, Domecq C; Alzheimer’s Disease Neuroimaging Initiative, Petersen GM, Syngal S, Brand R, Rustgi AK, Cote ML, Stoffel E, Olson SH, Roberts NJ, Akbari MR, Majewski J, Klein AP, Greenwood CMT, Gallinger S, Zogopoulos G.

PLoS Genet. 2019 Aug 30;15(8):e1008344. doi: 10.1371/journal.pgen.1008344. eCollection 2019 Aug.


Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE.

Cerdeira AS, O'Sullivan J, Ohuma EO, Harrington D, Szafranski P, Black R, Mackillop L, Impey L, Greenwood C, James T, Smith I, Papageorghiou AT, Knight M, Vatish M.

Hypertension. 2019 Oct;74(4):983-990. doi: 10.1161/HYPERTENSIONAHA.119.12739. Epub 2019 Aug 12.


Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing.

Shao X, Hudson M, Colmegna I, Greenwood CMT, Fritzler MJ, Awadalla P, Pastinen T, Bernatsky S.

Clin Epigenetics. 2019 Jul 31;11(1):110. doi: 10.1186/s13148-019-0699-9.


Cardiovascular risk and encoding-related hippocampal connectivity in older adults.

Meusel LC, Greenwood CE, Maione A, Tchistiakova E, MacIntosh BJ, Anderson ND.

BMC Neurosci. 2019 Jul 31;20(1):37. doi: 10.1186/s12868-019-0518-4.


Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells.

Ghashghaei M, Niazi TM, Aguilar-Mahecha A, Klein KO, Greenwood CMT, Basik M, Muanza TM.

Sci Rep. 2019 Jun 20;9(1):8838. doi: 10.1038/s41598-019-44991-w.


A comparison of longitudinal modelling approaches: Alcohol and cannabis use from adolescence to young adulthood.

Greenwood CJ, Youssef GJ, Betts KS, Letcher P, Mcintosh J, Spry E, Hutchinson DM, Macdonald JA, Hagg LJ, Sanson A, Toumbourou JW, Olsson CA.

Drug Alcohol Depend. 2019 Aug 1;201:58-64. doi: 10.1016/j.drugalcdep.2019.05.001. Epub 2019 May 29.


General psychopathology, internalising and externalising in children and functional outcomes in late adolescence.

Sallis H, Szekely E, Neumann A, Jolicoeur-Martineau A, van IJzendoorn M, Hillegers M, Greenwood CMT, Meaney MJ, Steiner M, Tiemeier H, Wazana A, Pearson RM, Evans J.

J Child Psychol Psychiatry. 2019 Nov;60(11):1183-1190. doi: 10.1111/jcpp.13067. Epub 2019 May 2.


Maternal mental health and infant emotional reactivity: a 20-year two-cohort study of preconception and perinatal exposures.

Spry E, Moreno-Betancur M, Becker D, Romaniuk H, Carlin JB, Molyneaux E, Howard LM, Ryan J, Letcher P, McIntosh J, Macdonald JA, Greenwood CJ, Thomson KC, McAnally H, Hancox R, Hutchinson DM, Youssef GJ, Olsson CA, Patton GC.

Psychol Med. 2019 Apr 10:1-11. doi: 10.1017/S0033291719000709. [Epub ahead of print]


Constrained instruments and their application to Mendelian randomization with pleiotropy.

Jiang L, Oualkacha K, Didelez V, Ciampi A, Rosa-Neto P, Benedet AL, Mathotaarachchi S, Richards JB, Greenwood CMT; Alzheimer’s Disease Neuroimaging Initiative.

Genet Epidemiol. 2019 Jun;43(4):373-401. doi: 10.1002/gepi.22184. Epub 2019 Jan 12.


Integration of "omics" Data and Phenotypic Data Within a Unified Extensible Multimodal Framework.

Das S, Lecours Boucher X, Rogers C, Makowski C, Chouinard-Decorte F, Oros Klein K, Beck N, Rioux P, Brown ST, Mohaddes Z, Zweber C, Foing V, Forest M, O'Donnell KJ, Clark J, Meaney MJ, Greenwood CMT, Evans AC.

Front Neuroinform. 2018 Dec 18;12:91. doi: 10.3389/fninf.2018.00091. eCollection 2018.


Distinguishing differential susceptibility, diathesis-stress, and vantage sensitivity: Beyond the single gene and environment model.

Jolicoeur-Martineau A, Belsky J, Szekely E, Widaman KF, Pluess M, Greenwood C, Wazana A.

Dev Psychopathol. 2020 Feb;32(1):73-83. doi: 10.1017/S0954579418001438.


Adolescent Care-Orientation and Positive Development in Young Adulthood.

Hutchinson D, Youssef GJ, Buhagiar A, Teague S, Macdonald JA, Letcher P, Greenwood C, McIntosh J, Toumbourou JW, Hallam BWT, Skouteris H, Sanson A, Olsson CA.

J Adolesc Health. 2019 Jan;64(1):63-69. doi: 10.1016/j.jadohealth.2018.07.024.


Age-Related Changes in Femoral Head Trabecular Microarchitecture.

Greenwood C, Clement J, Dicken A, Evans P, Lyburn I, Martin RM, Stone N, Zioupos P, Rogers K.

Aging Dis. 2018 Dec 4;9(6):976-987. doi: 10.14336/AD.2018.0124. eCollection 2018 Dec.


Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Manousaki D, Dudding T, Haworth S, Hsu YH, Liu CT, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Ikram MA, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, de Groot LCPGM, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards JB.

Am J Hum Genet. 2018 Dec 6;103(6):1053. doi: 10.1016/j.ajhg.2018.11.010. No abstract available.


Retention strategies in longitudinal cohort studies: a systematic review and meta-analysis.

Teague S, Youssef GJ, Macdonald JA, Sciberras E, Shatte A, Fuller-Tyszkiewicz M, Greenwood C, McIntosh J, Olsson CA, Hutchinson D; SEED Lifecourse Sciences Theme.

BMC Med Res Methodol. 2018 Nov 26;18(1):151. doi: 10.1186/s12874-018-0586-7.


External cephalic version after previous cesarean section: A cohort study of 100 consecutive attempts.

Impey ORE, Greenwood CEL, Impey LWM.

Eur J Obstet Gynecol Reprod Biol. 2018 Dec;231:210-213. doi: 10.1016/j.ejogrb.2018.10.036. Epub 2018 Oct 22.


Investigating potential causal relationships between SNPs, DNA methylation and HDL.

Jiang L, Zhao K, Klein K, Canty AJ, Oualkacha K, Greenwood CMT.

BMC Proc. 2018 Sep 17;12(Suppl 9):20. doi: 10.1186/s12919-018-0117-x. eCollection 2018.


CpG-set association assessment of lipid concentration changes and DNA methylation.

Zhao K, Jiang L, Klein K, Greenwood CMT, Oualkacha K.

BMC Proc. 2018 Sep 17;12(Suppl 9):30. doi: 10.1186/s12919-018-0127-8. eCollection 2018.


Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuédé C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, Ohh M, Ferreira T, Greenwood C, Bridon G, Avizonis D, Ferbeyre G, Siegel P, Jones RG, Muller W, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I.

Cell Metab. 2018 Dec 4;28(6):817-832.e8. doi: 10.1016/j.cmet.2018.09.001. Epub 2018 Sep 20.


A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data.

Shokoohi F, Stephens DA, Bourque G, Pastinen T, Greenwood CMT, Labbe A.

Biometrics. 2019 Mar;75(1):210-221. doi: 10.1111/biom.12965. Epub 2018 Oct 9.


SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

Findlay S, Heath J, Luo VM, Malina A, Morin T, Coulombe Y, Djerir B, Li Z, Samiei A, Simo-Cheyou E, Karam M, Bagci H, Rahat D, Grapton D, Lavoie EG, Dove C, Khaled H, Kuasne H, Mann KK, Klein KO, Greenwood CM, Tabach Y, Park M, Côté JF, Masson JY, Maréchal A, Orthwein A.

EMBO J. 2018 Sep 14;37(18). pii: e100158. doi: 10.15252/embj.2018100158. Epub 2018 Aug 28.


Alternating optimization for G × E modelling with weighted genetic and environmental scores: Examples from the MAVAN study.

Jolicoeur-Martineau A, Wazana A, Szekely E, Steiner M, Fleming AS, Kennedy JL, Meaney MJ, Greenwood CMT.

Psychol Methods. 2019 Apr;24(2):196-216. doi: 10.1037/met0000175. Epub 2018 Aug 13.


PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores.

Chen LM, Yao N, Garg E, Zhu Y, Nguyen TTT, Pokhvisneva I, Hari Dass SA, Unternaehrer E, Gaudreau H, Forest M, McEwen LM, MacIsaac JL, Kobor MS, Greenwood CMT, Silveira PP, Meaney MJ, O'Donnell KJ.

BMC Bioinformatics. 2018 Aug 8;19(1):295. doi: 10.1186/s12859-018-2289-9.


Automated Language Environment Analysis: A Research Synthesis.

Greenwood CR, Schnitz AG, Irvin D, Tsai SF, Carta JJ.

Am J Speech Lang Pathol. 2018 May 3;27(2):853-867. doi: 10.1044/2017_AJSLP-17-0033.


Measuring and Estimating the Effect Sizes of Copy Number Variants on General Intelligence in Community-Based Samples.

Huguet G, Schramm C, Douard E, Jiang L, Labbe A, Tihy F, Mathonnet G, Nizard S, Lemyre E, Mathieu A, Poline JB, Loth E, Toro R, Schumann G, Conrod P, Pausova Z, Greenwood C, Paus T, Bourgeron T, Jacquemont S; IMAGEN Consortium.

JAMA Psychiatry. 2018 May 1;75(5):447-457. doi: 10.1001/jamapsychiatry.2018.0039.


X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells.

Ho B, Greenlaw K, Al Tuwaijri A, Moussette S, Martínez F, Giorgio E, Brusco A, Ferrero GB, Linhares ND, Valadares ER, Svartman M, Kalscheuer VM, Rodríguez Criado G, Laprise C, Greenwood CMT, Naumova AK.

Biol Sex Differ. 2018 Feb 20;9(1):10. doi: 10.1186/s13293-018-0169-7.


Heritable contributions versus genetic architecture.

Timpson NJ, Greenwood CMT, Soranzo N, Lawson DJ, Richards JB.

Nat Rev Genet. 2018 Feb 14;19(3):185. doi: 10.1038/nrg.2018.7. No abstract available.


An analytic approach for interpretable predictive models in high-dimensional data in the presence of interactions with exposures.

Bhatnagar SR, Yang Y, Khundrakpam B, Evans AC, Blanchette M, Bouchard L, Greenwood CMT.

Genet Epidemiol. 2018 Apr;42(3):233-249. doi: 10.1002/gepi.22112. Epub 2018 Feb 8.


Distinct homologous recombination gene expression profiles after neoadjuvant chemotherapy associated with clinical outcome in patients with ovarian cancer.

Kessous R, Octeau D, Klein K, Tonin PN, Greenwood CMT, Pelmus M, Laskov I, Kogan L, Salvador S, Lau S, Yasmeen A, Gotlieb WH.

Gynecol Oncol. 2018 Mar;148(3):553-558. doi: 10.1016/j.ygyno.2018.01.017. Epub 2018 Feb 1.


Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time.

Forest M, O'Donnell KJ, Voisin G, Gaudreau H, MacIsaac JL, McEwen LM, Silveira PP, Steiner M, Kobor MS, Meaney MJ, Greenwood CMT.

Epigenetics. 2018;13(1):19-32. doi: 10.1080/15592294.2017.1411443. Epub 2018 Jan 30.


Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation.

Sun J, Oualkacha K, Forgetta V, Zheng HF, Richards JB, Evans DS, Orwoll E, Greenwood CMT.

Sci Rep. 2018 Jan 9;8(1):220. doi: 10.1038/s41598-017-18385-9.


EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner.

Arabzadeh A, McGregor K, Breton V, Van Der Kraak L, Akavia UD, Greenwood CMT, Beauchemin N.

Oncotarget. 2017 Nov 1;8(61):104330-104346. doi: 10.18632/oncotarget.22236. eCollection 2017 Nov 28.


New Fpg probe chemistry for direct detection of recombinase polymerase amplification on lateral flow strips.

Powell ML, Bowler FR, Martinez AJ, Greenwood CJ, Armes N, Piepenburg O.

Anal Biochem. 2018 Feb 15;543:108-115. doi: 10.1016/j.ab.2017.12.003. Epub 2017 Dec 9.


Genetic architecture: the shape of the genetic contribution to human traits and disease.

Timpson NJ, Greenwood CMT, Soranzo N, Lawson DJ, Richards JB.

Nat Rev Genet. 2018 Feb;19(2):110-124. doi: 10.1038/nrg.2017.101. Epub 2017 Dec 11. Review.


Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.

Cruceanu C, Schmouth JF, Torres-Platas SG, Lopez JP, Ambalavanan A, Darcq E, Gross F, Breton B, Spiegelman D, Rochefort D, Hince P, Petite JM, Gauthier J, Lafrenière RG, Dion PA, Greenwood CM, Kieffer BL, Alda M, Turecki G, Rouleau GA.

Mol Psychiatry. 2018 Oct;23(10):2050-2056. doi: 10.1038/mp.2017.223. Epub 2017 Nov 21.


Duration of Group A Streptococcus PCR positivity following antibiotic treatment of pharyngitis.

Homme JH, Greenwood CS, Cronk LB, Nyre LM, Uhl JR, Weaver AL, Patel R.

Diagn Microbiol Infect Dis. 2018 Feb;90(2):105-108. doi: 10.1016/j.diagmicrobio.2017.10.003. Epub 2017 Oct 12.


A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type.

Lakhal-Chaieb L, Greenwood CMT, Ouhourane M, Zhao K, Abdous B, Oualkacha K.

Stat Appl Genet Mol Biol. 2017 Nov 27;16(5-6):333-347. doi: 10.1515/sagmb-2016-0062.


Model-Free Linkage Analysis of a Binary Trait.

Xu W, Ma J, Greenwood CMT, Paterson AD, Bull SB.

Methods Mol Biol. 2017;1666:343-373. doi: 10.1007/978-1-4939-7274-6_17.


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