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Items: 9

1.

Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature.

O'Sullivan ME, Poitevin F, Sierra RG, Gati C, Dao EH, Rao Y, Aksit F, Ciftci H, Corsepius N, Greenhouse R, Hayes B, Hunter MS, Liang M, McGurk A, Mbgam P, Obrinsky T, Pardo-Avila F, Seaberg MH, Cheng AG, Ricci AJ, DeMirci H.

Nucleic Acids Res. 2018 Oct 12;46(18):9793-9804. doi: 10.1093/nar/gky693.

2.

Designer aminoglycosides prevent cochlear hair cell loss and hearing loss.

Huth ME, Han KH, Sotoudeh K, Hsieh YJ, Effertz T, Vu AA, Verhoeven S, Hsieh MH, Greenhouse R, Cheng AG, Ricci AJ.

J Clin Invest. 2015 Feb;125(2):583-92. doi: 10.1172/JCI77424. Epub 2015 Jan 2.

3.

Design, synthesis, and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain.

Lucas MC, Weikert RJ, Carter DS, Cai HY, Greenhouse R, Iyer PS, Lin CJ, Lee EK, Madera AM, Moore A, Ozboya K, Schoenfeld RC, Steiner S, Zhai Y, Lynch SM.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5559-66. doi: 10.1016/j.bmcl.2010.07.020. Epub 2010 Aug 4.

PMID:
20691589
4.

Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors.

Bannwart LM, Carter DS, Cai HY, Choy JC, Greenhouse R, Jaime-Figueroa S, Iyer PS, Lin CJ, Lee EK, Lucas MC, Lynch SM, Madera AM, Moore A, Ozboya K, Raptova L, Roetz R, Schoenfeld RC, Stein KA, Steiner S, Villa M, Weikert RJ, Zhai Y.

Bioorg Med Chem Lett. 2008 Dec 1;18(23):6062-6. doi: 10.1016/j.bmcl.2008.10.025. Epub 2008 Oct 11.

PMID:
18954985
5.

Discovery and synthesis of a novel and selective drug-like P2X(1) antagonist.

Jaime-Figueroa S, Greenhouse R, Padilla F, Dillon MP, Gever JR, Ford AP.

Bioorg Med Chem Lett. 2005 Jul 1;15(13):3292-5.

PMID:
15927468
6.

RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist.

Bonhaus DW, Flippin LA, Greenhouse RJ, Jaime S, Rocha C, Dawson M, Van Natta K, Chang LK, Pulido-Rios T, Webber A, Leung E, Eglen RM, Martin GR.

Br J Pharmacol. 1999 Jul;127(5):1075-82.

7.

RS 30026: a potent and effective calcium channel agonist.

Patmore L, Duncan GP, Clarke B, Anderson AJ, Greenhouse R, Pfister JR.

Br J Pharmacol. 1990 Apr;99(4):687-94.

8.

Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids.

Muchowski JM, Galeazzi E, Greenhouse R, Guzmán A, Peréz V, Ackerman N, Ballaron SA, Rovito JR, Tomolonis AJ, Young JM, et al.

J Med Chem. 1989 Jun;32(6):1202-7.

PMID:
2724294
9.

An evaluation of meprobamate in the treatment of alcoholism.

GREENBERG LA, LESTER D, DORA A, GREENHOUSE R, ROSENFELD J.

Ann N Y Acad Sci. 1957 May 9;67(10):816-9; discussion 820-1. No abstract available.

PMID:
13459152

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