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Items: 1 to 50 of 307

1.

Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD.

Sun X, Jefferson P, Zhou Q, Angelastro JM, Greene LA.

Mol Cancer Res. 2019 Nov 1. pii: molcanres.0631.2019. doi: 10.1158/1541-7786.MCR-19-0631. [Epub ahead of print]

PMID:
31676720
2.

Dominant-negative ATF5 rapidly depletes survivin in tumor cells.

Sun X, Angelastro JM, Merino D, Zhou Q, Siegelin MD, Greene LA.

Cell Death Dis. 2019 Sep 24;10(10):709. doi: 10.1038/s41419-019-1872-y.

3.

Stress-induced phospho-ubiquitin formation causes parkin degradation.

Kovalchuke L, Mosharov EV, Levy OA, Greene LA.

Sci Rep. 2019 Aug 12;9(1):11682. doi: 10.1038/s41598-019-47952-5.

4.

Atypical blastomycosis in a pregnant woman.

DeWitt CM, Shea K, Greene LA, Pierson JC.

Int J Womens Dermatol. 2018 Dec 29;5(2):131-133. doi: 10.1016/j.ijwd.2018.11.002. eCollection 2019 Jun.

5.

Ipilimumab-associated halo-like inflammatory reactions around nevi during therapy for metastatic melanoma.

Alniemi DT, Fischer A, Greene LA, Pierson JC.

Dermatol Online J. 2018 Jul 15;24(7). pii: 13030/qt8wd158r0.

6.

Context-dependent expression of a conditionally-inducible form of active Akt.

Park S, Burke RE, Kareva T, Kholodilov N, Aimé P, Franke TF, Levy O, Greene LA.

PLoS One. 2018 Jun 19;13(6):e0197899. doi: 10.1371/journal.pone.0197899. eCollection 2018.

7.

Activating Transcription Factor 4 (ATF4) Regulates Neuronal Activity by Controlling GABABR Trafficking.

Corona C, Pasini S, Liu J, Amar F, Greene LA, Shelanski ML.

J Neurosci. 2018 Jul 4;38(27):6102-6113. doi: 10.1523/JNEUROSCI.3350-17.2018. Epub 2018 Jun 6.

8.

Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of Sesn2.

Liu J, Amar F, Corona C, So RWL, Andrews SJ, Nagy PL, Shelanski ML, Greene LA.

Front Mol Neurosci. 2018 Mar 1;11:62. doi: 10.3389/fnmol.2018.00062. eCollection 2018.

9.

Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease.

Sun X, Aimé P, Dai D, Ramalingam N, Crary JF, Burke RE, Greene LA, Levy OA.

Exp Neurol. 2018 May;303:95-107. doi: 10.1016/j.expneurol.2018.01.015. Epub 2018 Feb 9.

10.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

11.

Cdc25A phosphatase: a key cell cycle protein that regulates neuron death in disease and development.

Biswas SC, Sanphui P, Chatterjee N, Kemeny S, Greene LA.

Cell Death Dis. 2017 Mar 23;8(3):e2692. doi: 10.1038/cddis.2017.115. No abstract available.

12.

Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloid.

Chatterjee N, Sanphui P, Kemeny S, Greene LA, Biswas SC.

Cell Death Discov. 2016 Dec 12;2:16083. doi: 10.1038/cddiscovery.2016.83. eCollection 2016.

13.

Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα.

Pasini S, Liu J, Corona C, Peze-Heidsieck E, Shelanski M, Greene LA.

Sci Rep. 2016 Nov 14;6:36952. doi: 10.1038/srep36952.

14.

A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers.

Karpel-Massler G, Horst BA, Shu C, Chau L, Tsujiuchi T, Bruce JN, Canoll P, Greene LA, Angelastro JM, Siegelin MD.

Clin Cancer Res. 2016 Sep 15;22(18):4698-711. doi: 10.1158/1078-0432.CCR-15-2827. Epub 2016 Apr 28.

15.

Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide.

Cates CC, Arias AD, Nakayama Wong LS, Lamé MW, Sidorov M, Cayanan G, Rowland DJ, Fung J, Karpel-Massler G, Siegelin MD, Greene LA, Angelastro JM.

Oncotarget. 2016 Mar 15;7(11):12718-30. doi: 10.18632/oncotarget.7212.

16.

Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models.

Aimé P, Sun X, Zareen N, Rao A, Berman Z, Volpicelli-Daley L, Bernd P, Crary JF, Levy OA, Greene LA.

J Neurosci. 2015 Jul 29;35(30):10731-49. doi: 10.1523/JNEUROSCI.0614-15.2015.

17.

Specific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memory.

Pasini S, Corona C, Liu J, Greene LA, Shelanski ML.

Cell Rep. 2015 Apr 14;11(2):183-91.

18.

Zoon's balanitis.

Hugh JM, Lesiak K, Greene LA, Pierson JC.

J Drugs Dermatol. 2014 Oct;13(10):1290-1.

PMID:
25763417
19.

Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease.

Romaní-Aumedes J, Canal M, Martín-Flores N, Sun X, Pérez-Fernández V, Wewering S, Fernández-Santiago R, Ezquerra M, Pont-Sunyer C, Lafuente A, Alberch J, Luebbert H, Tolosa E, Levy OA, Greene LA, Malagelada C.

Cell Death Dis. 2014 Aug 7;5:e1364. doi: 10.1038/cddis.2014.333.

20.

Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology.

Liu J, Pasini S, Shelanski ML, Greene LA.

Front Cell Neurosci. 2014 Jun 30;8:177. doi: 10.3389/fncel.2014.00177. eCollection 2014.

21.

Lack of anti-factor Xa assay standardization results in significant low molecular weight heparin (enoxaparin) dose variation in neonates and children.

Greene LA, Law C, Jung M, Walton S, Ignjatovic V, Monagle P, Raffini LJ.

J Thromb Haemost. 2014 Sep;12(9):1554-7. doi: 10.1111/jth.12641. Epub 2014 Jul 15.

22.

Beyond the platelet count: immature platelet fraction and thromboelastometry correlate with bleeding in patients with immune thrombocytopenia.

Greene LA, Chen S, Seery C, Imahiyerobo AM, Bussel JB.

Br J Haematol. 2014 Aug;166(4):592-600. doi: 10.1111/bjh.12929. Epub 2014 May 5.

PMID:
24797389
23.

A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neurons.

Zareen N, Biswas SC, Greene LA.

Cell Death Differ. 2013 Dec;20(12):1719-30. doi: 10.1038/cdd.2013.128.

24.

Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.

Jean YY, Ribe EM, Pero ME, Moskalenko M, Iqbal Z, Marks LJ, Greene LA, Troy CM.

Biochem J. 2013 Oct 1;455(1):15-25. doi: 10.1042/BJ20130556.

25.

Use of global assays to understand clinical phenotype in congenital factor VII deficiency.

Greene LA, Goldenberg NA, Simpson ML, Villalobos-Menuey E, Bombardier C, Acharya SS, Santiago-Borrero PJ, Cambara A, DiMichele DM.

Haemophilia. 2013 Sep;19(5):765-72. doi: 10.1111/hae.12160. Epub 2013 May 20.

PMID:
23682803
26.

Deep vein thrombosis: thrombolysis in the pediatric population.

Greene LA, Goldenberg NA.

Semin Intervent Radiol. 2012 Mar;29(1):36-43. doi: 10.1055/s-0032-1302450.

27.

ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkin.

Sun X, Liu J, Crary JF, Malagelada C, Sulzer D, Greene LA, Levy OA.

J Neurosci. 2013 Feb 6;33(6):2398-407. doi: 10.1523/JNEUROSCI.2292-12.2013.

28.
29.

Cell death and the developing enteric nervous system.

Chalazonitis A, Gershon MD, Greene LA.

Neurochem Int. 2012 Nov;61(6):839-47. doi: 10.1016/j.neuint.2012.01.028. Epub 2012 Feb 8. Review.

30.

Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein.

Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA.

J Biol Chem. 2012 Jan 13;287(3):2247-56. doi: 10.1074/jbc.M111.269431. Epub 2011 Nov 28.

31.

Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells.

Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA.

Dev Neurobiol. 2012 Jun;72(6):789-804. doi: 10.1002/dneu.20979.

32.

Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas.

Arias A, Lamé MW, Santarelli L, Hen R, Greene LA, Angelastro JM.

Oncogene. 2012 Feb 9;31(6):739-51. doi: 10.1038/onc.2011.276. Epub 2011 Jul 4.

33.

Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment.

Greene LA, Levy O, Malagelada C.

Cell Mol Neurobiol. 2011 Oct;31(7):969-78. doi: 10.1007/s10571-011-9671-8. Epub 2011 Mar 10.

34.

Gata2 is required for migration and differentiation of retinorecipient neurons in the superior colliculus.

Willett RT, Greene LA.

J Neurosci. 2011 Mar 23;31(12):4444-55. doi: 10.1523/JNEUROSCI.4616-10.2011.

35.

RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration.

Malagelada C, López-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA.

J Neurosci. 2011 Mar 2;31(9):3186-96. doi: 10.1523/JNEUROSCI.4011-10.2011.

36.

Sertad1 plays an essential role in developmental and pathological neuron death.

Biswas SC, Zhang Y, Iyirhiaro G, Willett RT, Rodriguez Gonzalez Y, Cregan SP, Slack RS, Park DS, Greene LA.

J Neurosci. 2010 Mar 17;30(11):3973-82. doi: 10.1523/JNEUROSCI.6421-09.2010.

37.

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.

Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, Greene LA.

J Neurosci. 2010 Jan 20;30(3):1166-75. doi: 10.1523/JNEUROSCI.3944-09.2010.

38.

Cbl negatively regulates JNK activation and cell death.

Sproul AA, Xu Z, Wilhelm M, Gire S, Greene LA.

Cell Res. 2009 Aug;19(8):950-61. doi: 10.1038/cr.2009.74.

39.

Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells.

Li G, Li W, Angelastro JM, Greene LA, Liu DX.

Mol Cancer Res. 2009 Jun;7(6):933-43. doi: 10.1158/1541-7786.MCR-08-0365. Epub 2009 Jun 16.

40.

Protocol for culturing sympathetic neurons from rat superior cervical ganglia (SCG).

Zareen N, Greene LA.

J Vis Exp. 2009 Jan 30;(23). pii: 988. doi: 10.3791/988.

41.

Isolation and culture of post-natal mouse cerebellar granule neuron progenitor cells and neurons.

Lee HY, Greene LA, Mason CA, Manzini MC.

J Vis Exp. 2009 Jan 16;(23). pii: 990. doi: 10.3791/990.

42.

Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.

Levy OA, Malagelada C, Greene LA.

Apoptosis. 2009 Apr;14(4):478-500. doi: 10.1007/s10495-008-0309-3. Review.

43.

RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation.

Malagelada C, Jin ZH, Greene LA.

J Neurosci. 2008 Dec 31;28(53):14363-71. doi: 10.1523/JNEUROSCI.3928-08.2008.

44.

The transcription factor ATF5: role in neurodevelopment and neural tumors.

Greene LA, Lee HY, Angelastro JM.

J Neurochem. 2009 Jan;108(1):11-22. doi: 10.1111/j.1471-4159.2008.05749.x. Epub 2008 Nov 15. Review.

45.

Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction.

Biswas SC, Buteau J, Greene LA.

Neurochem Res. 2008 Sep;33(9):1845-51. doi: 10.1007/s11064-008-9646-4. Epub 2008 Mar 20.

PMID:
18351462
47.

Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH.

Wilhelm M, Kukekov NV, Xu Z, Greene LA.

Dev Neurosci. 2007;29(4-5):355-62.

PMID:
17762203
48.
50.

Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.

Biswas SC, Shi Y, Vonsattel JP, Leung CL, Troy CM, Greene LA.

J Neurosci. 2007 Jan 24;27(4):893-900.

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