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Preventing preventable chronic disease: An essential goal.

Greenberg H, Pi-Sunyer FX.

Prog Cardiovasc Dis. 2019 Aug 14. pii: S0033-0620(19)30104-5. doi: 10.1016/j.pcad.2019.08.002. [Epub ahead of print] No abstract available.


Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells.

Feng N, Hu L, Ding S, Sanyal M, Zhao B, Sankaran B, Ramani S, McNeal M, Yasukawa LL, Song Y, Prasad BVV, Greenberg HB.

J Clin Invest. 2019 Aug 12;130:3839-3851. doi: 10.1172/JCI128382. eCollection 2019 Aug 12.


New records of Aedes aegypti and Aedes albopictus in eight Texas counties, U.S.A.

Greenberg HS, Wilson-Fallon AN, Peper ST, Haydett KM, Presley SM.

J Vector Ecol. 2019 Jun;44(1):199-200. doi: 10.1111/jvec.12345. No abstract available.


Midazolam Limited Sampling Strategy With a Population Pharmacokinetic Approach to Simultaneously Estimate Cytochrome P450 (CYP) 3A Constitutive, Inhibition, and Induction/Activation Conditions in Healthy Adults.

Yang J, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Stoch SA, Bertino JS Jr, Nafziger AN, Ma JD.

J Clin Pharmacol. 2019 May 3. doi: 10.1002/jcph.1440. [Epub ahead of print]


Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.

Paudel P, Zhang Q, Leung C, Greenberg HC, Guo Y, Chern YH, Dong A, Li Y, Vedadi M, Zhuang Z, Tong Y.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7288-7297. doi: 10.1073/pnas.1815027116. Epub 2019 Mar 26.


Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals.

Henry C, Zheng NY, Huang M, Cabanov A, Rojas KT, Kaur K, Andrews SF, Palm AE, Chen YQ, Li Y, Hoskova K, Utset HA, Vieira MC, Wrammert J, Ahmed R, Holden-Wiltse J, Topham DJ, Treanor JJ, Ertl HC, Schmader KE, Cobey S, Krammer F, Hensley SE, Greenberg H, He XS, Wilson PC.

Cell Host Microbe. 2019 Mar 13;25(3):357-366.e6. doi: 10.1016/j.chom.2019.01.002. Epub 2019 Feb 19.


Profiling of rotavirus 3'UTR-binding proteins reveals the ATP synthase subunit ATP5B as a host factor that supports late-stage virus replication.

Ren L, Ding S, Song Y, Li B, Ramanathan M, Co J, Amieva MR, Khavari PA, Greenberg HB.

J Biol Chem. 2019 Apr 12;294(15):5993-6006. doi: 10.1074/jbc.RA118.006004. Epub 2019 Feb 15.


Diminished B-Cell Response After Repeat Influenza Vaccination.

Sanyal M, Holmes TH, Maecker HT, Albrecht RA, Dekker CL, He XS, Greenberg HB.

J Infect Dis. 2019 Apr 19;219(10):1586-1595. doi: 10.1093/infdis/jiy685. Erratum in: J Infect Dis. 2019 Apr 19;219(10):1683.


Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells.

Ding S, Zhu S, Ren L, Feng N, Song Y, Ge X, Li B, Flavell RA, Greenberg HB.

Elife. 2018 Nov 21;7. pii: e39494. doi: 10.7554/eLife.39494.


New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.

Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M.

Nature. 2018 Aug;560(7717):198-203. doi: 10.1038/s41586-018-0372-z. Epub 2018 Jul 25.


Ventilator Weaning and Excursion Time Index: One Step Closer to the Quantum Leap?

Gottesman E, Palkar A, Greenberg H.

Lung. 2018 Oct;196(5):503-504. doi: 10.1007/s00408-018-0138-2. Epub 2018 Jul 20. No abstract available.


[No title available]

Greenberg HB, Griffin DE.

Curr Opin Virol. 2018 Apr;29:v-vii. doi: 10.1016/j.coviro.2018.04.005. No abstract available.


Midazolam Single Time Point Concentrations to Estimate Exposure and Cytochrome P450 (CYP) 3A Constitutive Activity Utilizing Limited Sampling Strategy With a Population Pharmacokinetic Approach.

Yang J, Patel M, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Aubrey Stoch S, Bertino JS Jr, Nafziger AN, Ma JD.

J Clin Pharmacol. 2018 Sep;58(9):1205-1213. doi: 10.1002/jcph.1125. Epub 2018 Apr 17.


STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection.

Ding S, Diep J, Feng N, Ren L, Li B, Ooi YS, Wang X, Brulois KF, Yasukawa LL, Li X, Kuo CJ, Solomon DA, Carette JE, Greenberg HB.

Nat Commun. 2018 Apr 16;9(1):1485. doi: 10.1038/s41467-018-03782-z.


Reply to: "Comments and question on "Selective inhibition of endothelial NF-κB signaling attenuates chronic intermittent hypoxia-induced atherosclerosis in mice"".

Song D, Fang G, Mao SZ, Ye X, Liu G, Miller EJ, Greenberg H, Liu SF.

Atherosclerosis. 2018 May;272:248. doi: 10.1016/j.atherosclerosis.2018.03.034. Epub 2018 Mar 20. No abstract available.


Serial Diaphragm Ultrasonography to Predict Successful Discontinuation of Mechanical Ventilation.

Palkar A, Mayo P, Singh K, Koenig S, Narasimhan M, Singh A, Darabaner R, Greenberg H, Gottesman E.

Lung. 2018 Jun;196(3):363-368. doi: 10.1007/s00408-018-0106-x. Epub 2018 Mar 19.


Predictive Modeling for West Nile Virus and Mosquito Surveillance in Lubbock, Texas.

Peper ST, Dawson DE, Dacko N, Athanasiou K, Hunter J, Loko F, Almas S, Sorensen GE, Urban KN, Wilson-Fallon AN, Haydett KM, Greenberg HS, Gibson AG, Presley SM.

J Am Mosq Control Assoc. 2018 Mar;34(1):18-24. doi: 10.2987/17-6714.1.


Selective inhibition of endothelial NF-κB signaling attenuates chronic intermittent hypoxia-induced atherosclerosis in mice.

Song D, Fang G, Mao SZ, Ye X, Liu G, Miller EJ, Greenberg H, Liu SF.

Atherosclerosis. 2018 Mar;270:68-75. doi: 10.1016/j.atherosclerosis.2018.01.027. Epub 2018 Jan 31.


Identification and Characterization at the Single-Cell Level of Cytokine-Producing Circulating Cells in Children With Dengue.

Perdomo-Celis F, Romero F, Salgado DM, Vega R, Rodríguez J, Angel J, Franco MA, Greenberg HB, Narváez CF.

J Infect Dis. 2018 Apr 11;217(9):1472-1480. doi: 10.1093/infdis/jiy053.


Diaphragm Excursion-Time Index: A New Parameter Using Ultrasonography to Predict Extubation Outcome.

Palkar A, Narasimhan M, Greenberg H, Singh K, Koenig S, Mayo P, Gottesman E.

Chest. 2018 May;153(5):1213-1220. doi: 10.1016/j.chest.2018.01.007. Epub 2018 Jan 17.


First record of Aedes aegypti and Aedes albopictus in thirteen Panhandle region counties of Texas, U.S.A.

Peper ST, Wilson-Fallon A, Haydett K, Greenberg H, Presley SM.

J Vector Ecol. 2017 Dec;42(2):352-354. doi: 10.1111/jvec.12276. No abstract available.


Rotavirus infection.

Crawford SE, Ramani S, Tate JE, Parashar UD, Svensson L, Hagbom M, Franco MA, Greenberg HB, O'Ryan M, Kang G, Desselberger U, Estes MK.

Nat Rev Dis Primers. 2017 Nov 9;3:17083. doi: 10.1038/nrdp.2017.83. Review.


Rotavirus Degrades Multiple Interferon (IFN) Type Receptors To Inhibit IFN Signaling and Protects against Mortality from Endotoxin in Suckling Mice.

Sen A, Sharma A, Greenberg HB.

J Virol. 2017 Dec 14;92(1). pii: e01394-17. doi: 10.1128/JVI.01394-17. Print 2018 Jan 1.


Primary choriocarcinoma in postmenopausal women: Two case reports and review of the Texas Cancer Registry.

Rafanan LF, Greenberg H, Rondeau NU, Mulla ZD, Boman DA.

Gynecol Oncol Rep. 2017 Oct 3;22:69-71. doi: 10.1016/j.gore.2017.09.016. eCollection 2017 Nov.


The epidemiological challenge of traditional chronic disease risk factors in emerging economies.

Greenberg H.

Int J Epidemiol. 2017 Oct 1;46(5):1351-1353. doi: 10.1093/ije/dyx214. No abstract available.


Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries.

Greenberg HZE, Carlton-Carew SRE, Khan DM, Zargaran AK, Jahan KS, Vanessa Ho WS, Albert AP.

Vascul Pharmacol. 2017 Sep;96-98:53-62. doi: 10.1016/j.vph.2017.08.005. Epub 2017 Sep 1.


DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes.

Lumb JH, Li Q, Popov LM, Ding S, Keith MT, Merrill BD, Greenberg HB, Li JB, Carette JE.

Cell Rep. 2017 Jul 25;20(4):819-831. doi: 10.1016/j.celrep.2017.06.085.


A call to incorporate systems theory and human factors into the existing investigation of harm in clinical research involving healthcare products.

Edwards BD, Bégaud B, Daemen E, Dokas I, Fishbein JM, Greenberg HE, Hochberg A, Le Louet H, Lyngvig J, Mogles N, Owen K, Prendergast C, Rejzek M, Trantza S, Webb DJ, Whalen M, Whiteley S.

Br J Clin Pharmacol. 2017 Nov;83(11):2339-2342. doi: 10.1111/bcp.13353. Epub 2017 Jul 19.


VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans.

Nair N, Feng N, Blum LK, Sanyal M, Ding S, Jiang B, Sen A, Morton JM, He XS, Robinson WH, Greenberg HB.

Sci Transl Med. 2017 Jun 21;9(395). pii: eaam5434. doi: 10.1126/scitranslmed.aam5434.


Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.

Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, Zhao Y, Jurado KA, Feng N, Shan L, Kluger Y, Lu J, Abraham C, Fikrig E, Greenberg HB, Flavell RA.

Nature. 2017 Jun 29;546(7660):667-670. doi: 10.1038/nature22967. Epub 2017 Jun 21.


Multicenter Automatic Defibrillator Implantation Trial-Subcutaneous Implantable Cardioverter Defibrillator (MADIT S-ICD): Design and clinical protocol.

Kutyifa V, Beck C, Brown MW, Cannom D, Daubert J, Estes M, Greenberg H, Goldenberg I, Hammes S, Huang D, Klein H, Knops R, Kosiborod M, Poole J, Schuger C, Singh JP, Solomon S, Wilber D, Zareba W, Moss AJ; MADIT S-ICD Executive Committee.

Am Heart J. 2017 Jul;189:158-166. doi: 10.1016/j.ahj.2017.04.014. Epub 2017 May 4.


Comprehensive review of visual defects reported with topiramate.

Ford L, Goldberg JL, Selan F, Greenberg HE, Shi Y.

Clin Ophthalmol. 2017 May 23;11:983-992. doi: 10.2147/OPTH.S125768. eCollection 2017. Review.


Structured Risk Assessment for First-in-Human Studies.

van Iersel MT, Greenberg HE, Westrick ML.

Ther Innov Regul Sci. 2017 May;51(3):288-297. doi: 10.1177/2168479017705156.


Safety in FIH Trials: A Summary of the Symposium "Fatal Drug Trial in Phase 1: Understanding Risk, Subject Safety, Timelines, and Cost".

Greenberg HE, van Iersel MT, Westrick ML, Smith WB.

Ther Innov Regul Sci. 2017 May;51(3):276-284. doi: 10.1177/2168479017706404.


Hot Button Protocol and Operational Issues Between Sponsors and Sites in Clinical Pharmacology Studies: A Moderated Forum Session.

Steinman GL, Smith WB, Westrick ML, Greenberg HE.

Ther Innov Regul Sci. 2017 May;51(3):298-302. doi: 10.1177/2168479017705688.


Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis.

Li B, Ding S, Feng N, Mooney N, Ooi YS, Ren L, Diep J, Kelly MR, Yasukawa LL, Patton JT, Yamazaki H, Shirao T, Jackson PK, Greenberg HB.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):E3642-E3651. doi: 10.1073/pnas.1619266114. Epub 2017 Apr 17.


State Requirements for Automated External Defibrillators in American Schools: Framing the Debate About Legislative Action.

Sherrid MV, Aagaard P, Serrato S, Arabadjian ME, Lium JM, Lium JD, Greenberg HM.

J Am Coll Cardiol. 2017 Apr 4;69(13):1735-1743. doi: 10.1016/j.jacc.2017.01.033. Review. Erratum in: J Am Coll Cardiol. 2017 May 16;69(19):2473.


Trafficking receptor signatures define blood plasmablasts responding to tissue-specific immune challenge.

Seong Y, Lazarus NH, Sutherland L, Habtezion A, Abramson T, He XS, Greenberg HB, Butcher EC.

JCI Insight. 2017 Mar 23;2(6):e90233. doi: 10.1172/jci.insight.90233.


And Why So Great a "No?": The Donor and Academic Communities' Failure to Confront Global Chronic Disease.

Greenberg H, Leeder SR, Raymond SU.

Glob Heart. 2016 Dec;11(4):381-385. doi: 10.1016/j.gheart.2016.10.018. Review.


The Funding for the NCD: The Optimistic View.

Greenberg H, Narula J.

Glob Heart. 2016 Dec;11(4):369-370. doi: 10.1016/j.gheart.2016.11.001. No abstract available.


The calcilytics Calhex-231 and NPS 2143 and the calcimimetic Calindol reduce vascular reactivity via inhibition of voltage-gated Ca2+ channels.

Greenberg HZE, Jahan KS, Shi J, Vanessa Ho WS, Albert AP.

Eur J Pharmacol. 2016 Nov 15;791:659-668. doi: 10.1016/j.ejphar.2016.10.008. Epub 2016 Oct 8.


Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex.

Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, Greenberg HB.

PLoS Pathog. 2016 Oct 5;12(10):e1005929. doi: 10.1371/journal.ppat.1005929. eCollection 2016 Oct.


Total and Envelope Protein-Specific Antibody-Secreting Cell Response in Pediatric Dengue Is Highly Modulated by Age and Subsequent Infections.

Toro JF, Salgado DM, Vega R, Rodríguez JA, Rodríguez LS, Angel J, Franco MA, Greenberg HB, Narváez CF.

PLoS One. 2016 Aug 25;11(8):e0161795. doi: 10.1371/journal.pone.0161795. eCollection 2016.


Is uveitis associated with topiramate use? A cumulative review.

Goldberg JL, Lau AG, Fan B, Ford L, Greenberg HE.

Clin Ophthalmol. 2016 Aug 2;10:1467-70. doi: 10.2147/OPTH.S104847. eCollection 2016.


Correction: Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.

Lin JD, Feng N, Sen A, Balan M, Tseng HC, McElrath C, Smirnov SV, Peng J, Yasukawa LL, Durbin RK, Durbin JE, Greenberg HB, Kotenko SV.

PLoS Pathog. 2016 Jun 15;12(6):e1005726. doi: 10.1371/journal.ppat.1005726. eCollection 2016 Jun.


Patch clamp.

Brown AP, Greenberg HZ.

Br J Hosp Med (Lond). 2016 May;77(5):C74-7. doi: 10.12968/hmed.2016.77.5.C74. Review. No abstract available.


Inhibition of prostacyclin and thromboxane biosynthesis in healthy volunteers by single and multiple doses of acetaminophen and indomethacin.

Schwartz JI, Musser BJ, Tanaka WK, Taggart WV, Mehta A, Gottesdiener KM, Greenberg HE.

Clin Pharmacol Drug Dev. 2015 Sep;4(5):337-45. doi: 10.1002/cpdd.194. Epub 2015 Jul 17.


Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.

Lin JD, Feng N, Sen A, Balan M, Tseng HC, McElrath C, Smirnov SV, Peng J, Yasukawa LL, Durbin RK, Durbin JE, Greenberg HB, Kotenko SV.

PLoS Pathog. 2016 Apr 29;12(4):e1005600. doi: 10.1371/journal.ppat.1005600. eCollection 2016 Apr. Erratum in: PLoS Pathog. 2016 Jun 15;12 (6):e1005726.


Stimulation of calcium-sensing receptors induces endothelium-dependent vasorelaxations via nitric oxide production and activation of IKCa channels.

Greenberg HZ, Shi J, Jahan KS, Martinucci MC, Gilbert SJ, Vanessa Ho WS, Albert AP.

Vascul Pharmacol. 2016 May;80:75-84. doi: 10.1016/j.vph.2016.01.001. Epub 2016 Jan 6.


Unusual primary syphilis: Presentation of a likely case with a review of the stages of acquired syphilis, its differential diagnoses, management, and current recommendations.

Watts PJ, Greenberg HL, Khachemoune A.

Int J Dermatol. 2016 Jul;55(7):714-28. doi: 10.1111/ijd.13206. Epub 2016 Jan 12. Review.


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