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Items: 1 to 50 of 114

1.

Label-Free Digital Holo-tomographic Microscopy Reveals Virus-Induced Cytopathic Effects in Live Cells.

Yakimovich A, Witte R, Andriasyan V, Georgi F, Greber UF.

mSphere. 2018 Nov 21;3(6). pii: e00599-18. doi: 10.1128/mSphereDirect.00599-18.

2.

Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition.

Daga N, Eicher S, Kannan A, Casanova A, Low SH, Kreibich S, Andritschke D, Emmenlauer M, Jenkins JL, Hardt WD, Greber UF, Dehio C, von Mering C.

Nucleic Acids Res. 2018 Oct 12;46(18):9309-9320. doi: 10.1093/nar/gky798.

3.

A Single Point Mutation in the Rhinovirus 2B Protein Reduces the Requirement for Phosphatidylinositol 4-Kinase Class III Beta in Viral Replication.

Roulin PS, Murer LP, Greber UF.

J Virol. 2018 Nov 12;92(23). pii: e01462-18. doi: 10.1128/JVI.01462-18. Print 2018 Dec 1.

4.

How Computational Models Enable Mechanistic Insights into Virus Infection.

Sbalzarini IF, Greber UF.

Methods Mol Biol. 2018;1836:609-631. doi: 10.1007/978-1-4939-8678-1_30. Review.

PMID:
30151595
5.

Single entity resolution valving of nanoscopic species in liquids.

Eberle P, Höller C, Müller P, Suomalainen M, Greber UF, Eghlidi H, Poulikakos D.

Nat Nanotechnol. 2018 Jul;13(7):578-582. doi: 10.1038/s41565-018-0150-y. Epub 2018 May 21.

6.

MxB is an interferon-induced restriction factor of human herpesviruses.

Crameri M, Bauer M, Caduff N, Walker R, Steiner F, Franzoso FD, Gujer C, Boucke K, Kucera T, Zbinden A, Münz C, Fraefel C, Greber UF, Pavlovic J.

Nat Commun. 2018 May 17;9(1):1980. doi: 10.1038/s41467-018-04379-2.

7.

Concepts in Light Microscopy of Viruses.

Witte R, Andriasyan V, Georgi F, Yakimovich A, Greber UF.

Viruses. 2018 Apr 18;10(4). pii: E202. doi: 10.3390/v10040202. Review.

8.

Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton.

Wang IH, Burckhardt CJ, Yakimovich A, Greber UF.

Viruses. 2018 Mar 31;10(4). pii: E166. doi: 10.3390/v10040166. Review.

9.

Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor.

Stichling N, Suomalainen M, Flatt JW, Schmid M, Pacesa M, Hemmi S, Jungraithmayr W, Maler MD, Freudenberg MA, Plückthun A, May T, Köster M, Fejer G, Greber UF.

PLoS Pathog. 2018 Mar 9;14(3):e1006914. doi: 10.1371/journal.ppat.1006914. eCollection 2018 Mar.

10.

Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death.

Lötzerich M, Roulin PS, Boucke K, Witte R, Georgiev O, Greber UF.

Cell Death Dis. 2018 Feb 15;9(3):272. doi: 10.1038/s41419-018-0306-6.

11.

Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.

Schmid M, Ernst P, Honegger A, Suomalainen M, Zimmermann M, Braun L, Stauffer S, Thom C, Dreier B, Eibauer M, Kipar A, Vogel V, Greber UF, Medalia O, Plückthun A.

Nat Commun. 2018 Jan 31;9(1):450. doi: 10.1038/s41467-017-02707-6.

12.

Erratum for Maler et al., "Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages".

Maler MD, Nielsen PJ, Stichling N, Cohen I, Ruzsics Z, Wood C, Engelhard P, Suomalainen M, Gyory I, Huber M, Müller-Quernheim J, Schamel WW, Gordon S, Jakob T, Martin SF, Jahnen-Dechent W, Greber UF, Freudenberg MA, Fejer G.

MBio. 2017 Sep 26;8(5). pii: e01445-17. doi: 10.1128/mBio.01445-17. No abstract available.

13.

Small-size recombinant adenoviral hexon protein fragments for the production of virus-type specific antibodies.

Pacesa M, Hendrickx R, Bieri M, Flatt JW, Greber UF, Hemmi S.

Virol J. 2017 Aug 18;14(1):158. doi: 10.1186/s12985-017-0822-5.

14.

Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages.

Maler MD, Nielsen PJ, Stichling N, Cohen I, Ruzsics Z, Wood C, Engelhard P, Suomalainen M, Gyory I, Huber M, Müller-Quernheim J, Schamel WWA, Gordon S, Jakob T, Martin SF, Jahnen-Dechent W, Greber UF, Freudenberg MA, Fejer G.

MBio. 2017 Aug 1;8(4). pii: e00670-17. doi: 10.1128/mBio.00670-17. Erratum in: MBio. 2017 Sep 26;8(5):.

15.

Inhibition of Poxvirus Gene Expression and Genome Replication by Bisbenzimide Derivatives.

Yakimovich A, Huttunen M, Zehnder B, Coulter LJ, Gould V, Schneider C, Kopf M, McInnes CJ, Greber UF, Mercer J.

J Virol. 2017 Aug 24;91(18). pii: e00838-17. doi: 10.1128/JVI.00838-17. Print 2017 Sep 15.

16.

The adenovirus major core protein VII is dispensable for virion assembly but is essential for lytic infection.

Ostapchuk P, Suomalainen M, Zheng Y, Boucke K, Greber UF, Hearing P.

PLoS Pathog. 2017 Jun 19;13(6):e1006455. doi: 10.1371/journal.ppat.1006455. eCollection 2017 Jun.

17.

Cell Cycle-Dependent Expression of Adeno-Associated Virus 2 (AAV2) Rep in Coinfections with Herpes Simplex Virus 1 (HSV-1) Gives Rise to a Mosaic of Cells Replicating either AAV2 or HSV-1.

Franzoso FD, Seyffert M, Vogel R, Yakimovich A, de Andrade Pereira B, Meier AF, Sutter SO, Tobler K, Vogt B, Greber UF, Büning H, Ackermann M, Fraefel C.

J Virol. 2017 Jul 12;91(15). pii: e00357-17. doi: 10.1128/JVI.00357-17. Print 2017 Aug 1.

18.

The nuclear export factor CRM1 controls juxta-nuclear microtubule-dependent virus transport.

Wang IH, Burckhardt CJ, Yakimovich A, Morf MK, Greber UF.

J Cell Sci. 2017 Jul 1;130(13):2185-2195. doi: 10.1242/jcs.203794. Epub 2017 May 17.

19.

Viral mechanisms for docking and delivering at nuclear pore complexes.

Flatt JW, Greber UF.

Semin Cell Dev Biol. 2017 Aug;68:59-71. doi: 10.1016/j.semcdb.2017.05.008. Epub 2017 May 12. Review.

20.

Cell Cycle-Dependent Kinase Cdk9 Is a Postexposure Drug Target against Human Adenoviruses.

Prasad V, Suomalainen M, Hemmi S, Greber UF.

ACS Infect Dis. 2017 Jun 9;3(6):398-405. doi: 10.1021/acsinfecdis.7b00009. Epub 2017 Apr 27.

21.

Editorial: An expanded view of viruses.

Greber UF, Bartenschlager R.

FEMS Microbiol Rev. 2017 Jan;41(1):1-4. doi: 10.1093/femsre/fuw044. No abstract available.

PMID:
28087690
22.

Infectio: a Generic Framework for Computational Simulation of Virus Transmission between Cells.

Yakimovich A, Yakimovich Y, Schmid M, Mercer J, Sbalzarini IF, Greber UF.

mSphere. 2016 Feb 10;1(1). pii: e00078-15. doi: 10.1128/mSphere.00078-15. eCollection 2016 Jan-Feb.

23.

A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes.

Gschweitl M, Ulbricht A, Barnes CA, Enchev RI, Stoffel-Studer I, Meyer-Schaller N, Huotari J, Yamauchi Y, Greber UF, Helenius A, Peter M.

Elife. 2016 Mar 23;5:e13841. doi: 10.7554/eLife.13841.

24.

Principles of Virus Uncoating: Cues and the Snooker Ball.

Yamauchi Y, Greber UF.

Traffic. 2016 Jun;17(6):569-92. doi: 10.1111/tra.12387. Epub 2016 Mar 31. Review.

25.

Virus and Host Mechanics Support Membrane Penetration and Cell Entry.

Greber UF.

J Virol. 2016 Mar 28;90(8):3802-3805. doi: 10.1128/JVI.02568-15. Print 2016 Apr. Review.

26.

Plaque2.0-A High-Throughput Analysis Framework to Score Virus-Cell Transmission and Clonal Cell Expansion.

Yakimovich A, Andriasyan V, Witte R, Wang IH, Prasad V, Suomalainen M, Greber UF.

PLoS One. 2015 Sep 28;10(9):e0138760. doi: 10.1371/journal.pone.0138760. eCollection 2015.

27.

Fluorescence Tracking of Genome Release during Mechanical Unpacking of Single Viruses.

Ortega-Esteban A, Bodensiek K, San Martín C, Suomalainen M, Greber UF, de Pablo PJ, Schaap IA.

ACS Nano. 2015 Nov 24;9(11):10571-9. doi: 10.1021/acsnano.5b03020. Epub 2015 Sep 24.

28.

Misdelivery at the Nuclear Pore Complex-Stopping a Virus Dead in Its Tracks.

Flatt JW, Greber UF.

Cells. 2015 Jul 28;4(3):277-96. doi: 10.3390/cells4030277. Review.

29.

Co-option of Membrane Wounding Enables Virus Penetration into Cells.

Luisoni S, Suomalainen M, Boucke K, Tanner LB, Wenk MR, Guan XL, Grzybek M, Coskun Ü, Greber UF.

Cell Host Microbe. 2015 Jul 8;18(1):75-85. doi: 10.1016/j.chom.2015.06.006.

30.

Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A.

Ingold E, Vom Berg-Maurer CM, Burckhardt CJ, Lehnherr A, Rieder P, Keller PJ, Stelzer EH, Greber UF, Neuhauss SC, Gesemann M.

Biol Open. 2015 Jan 8;4(2):146-54. doi: 10.1242/bio.20148482.

31.

Rhinovirus uses a phosphatidylinositol 4-phosphate/cholesterol counter-current for the formation of replication compartments at the ER-Golgi interface.

Roulin PS, Lötzerich M, Torta F, Tanner LB, van Kuppeveld FJ, Wenk MR, Greber UF.

Cell Host Microbe. 2014 Nov 12;16(5):677-90. doi: 10.1016/j.chom.2014.10.003. Epub 2014 Nov 12.

32.

Chemical induction of unfolded protein response enhances cancer cell killing through lytic virus infection.

Prasad V, Suomalainen M, Pennauer M, Yakimovich A, Andriasyan V, Hemmi S, Greber UF.

J Virol. 2014 Nov;88(22):13086-98. doi: 10.1128/JVI.02156-14. Epub 2014 Sep 3.

33.

How cells tune viral mechanics--insights from biophysical measurements of influenza virus.

Greber UF.

Biophys J. 2014 Jun 3;106(11):2317-21. doi: 10.1016/j.bpj.2014.04.025. Review.

34.

Innate immunity to adenovirus.

Hendrickx R, Stichling N, Koelen J, Kuryk L, Lipiec A, Greber UF.

Hum Gene Ther. 2014 Apr;25(4):265-84. doi: 10.1089/hum.2014.001. Epub 2014 Apr 8. Review.

35.

Tracking viral genomes in host cells at single-molecule resolution.

Wang IH, Suomalainen M, Andriasyan V, Kilcher S, Mercer J, Neef A, Luedtke NW, Greber UF.

Cell Host Microbe. 2013 Oct 16;14(4):468-80. doi: 10.1016/j.chom.2013.09.004.

36.

A direct and versatile assay measuring membrane penetration of adenovirus in single cells.

Suomalainen M, Luisoni S, Boucke K, Bianchi S, Engel DA, Greber UF.

J Virol. 2013 Nov;87(22):12367-79. doi: 10.1128/JVI.01833-13. Epub 2013 Sep 11.

37.

Virus interactions with endocytic pathways in macrophages and dendritic cells.

Mercer J, Greber UF.

Trends Microbiol. 2013 Aug;21(8):380-8. doi: 10.1016/j.tim.2013.06.001. Epub 2013 Jul 3. Review.

PMID:
23830563
38.

iTRAQ-Based and Label-Free Proteomics Approaches for Studies of Human Adenovirus Infections.

Trinh HV, Grossmann J, Gehrig P, Roschitzki B, Schlapbach R, Greber UF, Hemmi S.

Int J Proteomics. 2013;2013:581862. doi: 10.1155/2013/581862. Epub 2013 Mar 11.

39.

Uncoating of non-enveloped viruses.

Suomalainen M, Greber UF.

Curr Opin Virol. 2013 Feb;3(1):27-33. doi: 10.1016/j.coviro.2012.12.004. Epub 2013 Jan 16. Review.

40.

Niclosamide is a proton carrier and targets acidic endosomes with broad antiviral effects.

Jurgeit A, McDowell R, Moese S, Meldrum E, Schwendener R, Greber UF.

PLoS Pathog. 2012;8(10):e1002976. doi: 10.1371/journal.ppat.1002976. Epub 2012 Oct 25.

41.

Adenovirus signalling in entry.

Wolfrum N, Greber UF.

Cell Microbiol. 2013 Jan;15(1):53-62. doi: 10.1111/cmi.12053. Epub 2012 Nov 13. Review.

PMID:
23083122
42.

Investigating endocytic pathways to the endoplasmic reticulum and to the cytosol using SNAP-trap.

Geiger R, Luisoni S, Johnsson K, Greber UF, Helenius A.

Traffic. 2013 Jan;14(1):36-46. doi: 10.1111/tra.12018. Epub 2012 Nov 12.

43.

Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: I. binding to DNA AND to hexon of the precursor to protein VI, pVI, of human adenovirus.

Graziano V, McGrath WJ, Suomalainen M, Greber UF, Freimuth P, Blainey PC, Luo G, Xie XS, Mangel WF.

J Biol Chem. 2013 Jan 18;288(3):2059-67. doi: 10.1074/jbc.M112.377150. Epub 2012 Oct 7.

44.

Adenoviruses - from pathogens to therapeutics: a report on the 10th International Adenovirus Meeting.

Greber UF, Arnberg N, Wadell G, Benkő M, Kremer EJ.

Cell Microbiol. 2013 Jan;15(1):16-23. doi: 10.1111/cmi.12031. Epub 2012 Oct 11. No abstract available.

PMID:
22985121
45.

Cell-free transmission of human adenovirus by passive mass transfer in cell culture simulated in a computer model.

Yakimovich A, Gumpert H, Burckhardt CJ, Lütschg VA, Jurgeit A, Sbalzarini IF, Greber UF.

J Virol. 2012 Sep;86(18):10123-37. doi: 10.1128/JVI.01102-12. Epub 2012 Jul 11.

46.

Too smart to fail-how viruses exploit the complexity of host cells during entry.

Greber UF, Cosset FL.

Curr Opin Virol. 2011 Jul;1(1):3-5. doi: 10.1016/j.coviro.2011.05.011. Epub 2011 Jun 22. No abstract available.

PMID:
22440561
47.

Avidity binding of human adenovirus serotypes 3 and 7 to the membrane cofactor CD46 triggers infection.

Trinh HV, Lesage G, Chennamparampil V, Vollenweider B, Burckhardt CJ, Schauer S, Havenga M, Greber UF, Hemmi S.

J Virol. 2012 Feb;86(3):1623-37. doi: 10.1128/JVI.06181-11. Epub 2011 Nov 30.

48.

Adenovirus-triggered innate signalling pathways.

Fejer G, Freudenberg M, Greber UF, Gyory I.

Eur J Microbiol Immunol (Bp). 2011 Dec;1(4):279-88. doi: 10.1556/EuJMI.1.2011.4.3. Epub 2011 Dec 23. Review.

49.

The dynactin complex enhances the speed of microtubule-dependent motions of adenovirus both towards and away from the nucleus.

Engelke MF, Burckhardt CJ, Morf MK, Greber UF.

Viruses. 2011 Mar;3(3):233-53. doi: 10.3390/v3030233. Epub 2011 Mar 9.

50.

Kinesin-1-mediated capsid disassembly and disruption of the nuclear pore complex promote virus infection.

Strunze S, Engelke MF, Wang IH, Puntener D, Boucke K, Schleich S, Way M, Schoenenberger P, Burckhardt CJ, Greber UF.

Cell Host Microbe. 2011 Sep 15;10(3):210-23. doi: 10.1016/j.chom.2011.08.010.

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