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Items: 15


Engineering Targeting Materials for Therapeutic Cancer Vaccines.

Briquez PS, Hauert S, de Titta A, Gray LT, Alpar AT, Swartz MA, Hubbell JA.

Front Bioeng Biotechnol. 2020 Feb 11;8:19. doi: 10.3389/fbioe.2020.00019. eCollection 2020. Review.


G-quadruplexes Sequester Free Heme in Living Cells.

Gray LT, Puig Lombardi E, Verga D, Nicolas A, Teulade-Fichou MP, Londoño-Vallejo A, Maizels N.

Cell Chem Biol. 2019 Dec 19;26(12):1681-1691.e5. doi: 10.1016/j.chembiol.2019.10.003. Epub 2019 Oct 23.


Targeted antibody and cytokine cancer immunotherapies through collagen affinity.

Ishihara J, Ishihara A, Sasaki K, Lee SS, Williford JM, Yasui M, Abe H, Potin L, Hosseinchi P, Fukunaga K, Raczy MM, Gray LT, Mansurov A, Katsumata K, Fukayama M, Kron SJ, Swartz MA, Hubbell JA.

Sci Transl Med. 2019 Apr 10;11(487). pii: eaau3259. doi: 10.1126/scitranslmed.aau3259.


Layer-specific chromatin accessibility landscapes reveal regulatory networks in adult mouse visual cortex.

Gray LT, Yao Z, Nguyen TN, Kim TK, Zeng H, Tasic B.

Elife. 2017 Jan 23;6. pii: e21883. doi: 10.7554/eLife.21883.


Biophysical properties of the clinical-stage antibody landscape.

Jain T, Sun T, Durand S, Hall A, Houston NR, Nett JH, Sharkey B, Bobrowicz B, Caffry I, Yu Y, Cao Y, Lynaugh H, Brown M, Baruah H, Gray LT, Krauland EM, Xu Y, Vásquez M, Wittrup KD.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):944-949. doi: 10.1073/pnas.1616408114. Epub 2017 Jan 17.


The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.

Tang W, Robles AI, Beyer RP, Gray LT, Nguyen GH, Oshima J, Maizels N, Harris CC, Monnat RJ Jr.

Hum Mol Genet. 2016 May 15;25(10):2060-2069. Epub 2016 Mar 16.


Adult mouse cortical cell taxonomy revealed by single cell transcriptomics.

Tasic B, Menon V, Nguyen TN, Kim TK, Jarsky T, Yao Z, Levi B, Gray LT, Sorensen SA, Dolbeare T, Bertagnolli D, Goldy J, Shapovalova N, Parry S, Lee C, Smith K, Bernard A, Madisen L, Sunkin SM, Hawrylycz M, Koch C, Zeng H.

Nat Neurosci. 2016 Feb;19(2):335-46. doi: 10.1038/nn.4216. Epub 2016 Jan 4.


Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs.

Nguyen GH, Tang W, Robles AI, Beyer RP, Gray LT, Welsh JA, Schetter AJ, Kumamoto K, Wang XW, Hickson ID, Maizels N, Monnat RJ Jr, Harris CC.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9905-10. doi: 10.1073/pnas.1404807111. Epub 2014 Jun 23.


G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD.

Gray LT, Vallur AC, Eddy J, Maizels N.

Nat Chem Biol. 2014 Apr;10(4):313-8. doi: 10.1038/nchembio.1475. Epub 2014 Mar 9.


PGBD5: a neural-specific intron-containing piggyBac transposase domesticated over 500 million years ago and conserved from cephalochordates to humans.

Pavelitz T, Gray LT, Padilla SL, Bailey AD, Weiner AM.

Mob DNA. 2013 Nov 1;4(1):23. doi: 10.1186/1759-8753-4-23.


The G4 genome.

Maizels N, Gray LT.

PLoS Genet. 2013 Apr;9(4):e1003468. doi: 10.1371/journal.pgen.1003468. Epub 2013 Apr 18.


What role (if any) does the highly conserved CSB-PGBD3 fusion protein play in Cockayne syndrome?

Weiner AM, Gray LT.

Mech Ageing Dev. 2013 May-Jun;134(5-6):225-33. doi: 10.1016/j.mad.2013.01.001. Epub 2013 Jan 28. Review.


Tethering of the conserved piggyBac transposase fusion protein CSB-PGBD3 to chromosomal AP-1 proteins regulates expression of nearby genes in humans.

Gray LT, Fong KK, Pavelitz T, Weiner AM.

PLoS Genet. 2012 Sep;8(9):e1002972. doi: 10.1371/journal.pgen.1002972. Epub 2012 Sep 27.


The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells.

Bailey AD, Gray LT, Pavelitz T, Newman JC, Horibata K, Tanaka K, Weiner AM.

DNA Repair (Amst). 2012 May 1;11(5):488-501. doi: 10.1016/j.dnarep.2012.02.004. Epub 2012 Apr 6.


Ubiquitin recognition by the Cockayne syndrome group B protein: binding will set you free.

Gray LT, Weiner AM.

Mol Cell. 2010 Jun 11;38(5):621-2. doi: 10.1016/j.molcel.2010.05.025.

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