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Generation of Alpha-1 Antitrypsin Knockout and PI*ZZ Ferrets Using Crispr/Cas9. A Genetic Model of Emphysema.

He N, Rosen BH, Gray JS, Evans IA, Zieger M, Yan Z, Borel F, Liang B, Sun X, Moll SR, Brodsky MH, Mueller C, Engelhardt JF.

Ann Am Thorac Soc. 2018 Dec;15(Supplement_4):S292-S293. doi: 10.1513/AnnalsATS.201806-429MG.


PsychoPy2: Experiments in behavior made easy.

Peirce J, Gray JR, Simpson S, MacAskill M, Höchenberger R, Sogo H, Kastman E, Lindeløv JK.

Behav Res Methods. 2019 Feb 7. doi: 10.3758/s13428-018-01193-y. [Epub ahead of print]


Visually Impaired OLder people’s Exercise programme for falls prevenTion (VIOLET): a feasibility study.

Adams N, Skelton D, Bailey C, Howel D, Coe D, Lampitt R, Wilkinson J, Fouweather T, de Jong LD, Gawler S, Deary V, Gray J, Waterman H, Parry SW.

Southampton (UK): NIHR Journals Library; 2019 Feb.


Correction: Riluzole reduces amyloid beta pathology, improves memory, and restores gene expression changes in a transgenic mouse model of early-onset Alzheimer's disease.

Okamato M, Gray JD, Larson CS, Kazim SF, Soya H, McEwen BS, Pereira AC.

Transl Psychiatry. 2019 Feb 4;9(1):61. doi: 10.1038/s41398-019-0408-7.


Genome-wide association studies of impulsive personality traits (BIS-11 and UPPSP) and drug experimentation in up to 22,861 adult research participants identify loci in the CACNA1I and CADM2 genes.

Sanchez-Roige S, Fontanillas P, Elson SL, Gray JC, de Wit H, MacKillop J, Palmer AA.

J Neurosci. 2019 Feb 4. pii: 2662-18. doi: 10.1523/JNEUROSCI.2662-18.2019. [Epub ahead of print]


Robust Cell Detection and Segmentation for Image Cytometry Reveal Th17 Cell Heterogeneity.

Tsujikawa T, Thibault G, Azimi V, Sivagnanam S, Banik G, Means C, Kawashima R, Clayburgh DR, Gray JW, Coussens LM, Chang YH.

Cytometry A. 2019 Feb 4. doi: 10.1002/cyto.a.23726. [Epub ahead of print]


Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus.

Maya-Martinez R, Alexander JAN, Otten CF, Ayala I, Vollmer D, Gray J, Bougault CM, Burt A, Laguri C, Fonvielle M, Arthur M, Strynadka NCJ, Vollmer W, Simorre JP.

Front Microbiol. 2019 Jan 18;9:3223. doi: 10.3389/fmicb.2018.03223. eCollection 2018.


Increased central adiposity and decreased subcutaneous adipose tissue 11β-hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance - a longitudinal cohort study.

Crowley RK, Woods CP, Hughes BA, Gray J, McCarthy T, Taylor AE, Gathercole LL, Shackleton CH, Crabtree N, Arlt W, Stewart PM, Tomlinson JW.

Clin Endocrinol (Oxf). 2019 Jan 22. doi: 10.1111/cen.13939. [Epub ahead of print]


Postprogression Outcomes for Osimertinib versus Standard-of-Care EGFR-TKI in Patients with Previously Untreated EGFR-mutated Advanced Non-Small Cell Lung Cancer.

Planchard D, Boyer MJ, Lee JS, Dechaphunkul A, Cheema PK, Takahashi T, Gray JE, Tiseo M, Ramalingam SS, Todd A, McKeown A, Rukazenkov Y, Ohe Y.

Clin Cancer Res. 2019 Jan 18. doi: 10.1158/1078-0432.CCR-18-3325. [Epub ahead of print]


Opioid Prescribing Rates in Nonmetropolitan and Metropolitan Counties Among Primary Care Providers Using an Electronic Health Record System - United States, 2014-2017.

García MC, Heilig CM, Lee SH, Faul M, Guy G, Iademarco MF, Hempstead K, Raymond D, Gray J.

MMWR Morb Mortal Wkly Rep. 2019 Jan 18;68(2):25-30. doi: 10.15585/mmwr.mm6802a1.


Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting.

Langer EM, Allen-Petersen BL, King SM, Kendsersky ND, Turnidge MA, Kuziel GM, Riggers R, Samatham R, Amery TS, Jacques SL, Sheppard BC, Korkola JE, Muschler JL, Thibault G, Chang YH, Gray JW, Presnell SC, Nguyen DG, Sears RC.

Cell Rep. 2019 Jan 15;26(3):608-623.e6. doi: 10.1016/j.celrep.2018.12.090.


Non-H3 CDR template selection in antibody modeling through machine learning.

Long X, Jeliazkov JR, Gray JJ.

PeerJ. 2019 Jan 11;7:e6179. doi: 10.7717/peerj.6179. eCollection 2019.


Chronic immobilization stress primes the hippocampal opioid system for oxycodone-associated learning in female but not male rats.

Reich B, Zhou Y, Goldstein E, Srivats SS, Contoreggi NH, Kogan JF, McEwen BS, Kreek MJ, Milner TA, Gray JD.

Synapse. 2019 Jan 10:e22088. doi: 10.1002/syn.22088. [Epub ahead of print]


A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24.

Spear ED, Alford RF, Babatz TD, Wood KM, Mossberg OW, Odinammadu K, Shilagardi K, Gray JJ, Michaelis S.

Methods. 2019 Jan 6. pii: S1046-2023(18)30120-8. doi: 10.1016/j.ymeth.2019.01.001. [Epub ahead of print] Review.


Publisher Correction: Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry.

Sanchez-Roige S, Fontanillas P, Elson SL; 23andMe Research Team, Pandit A, Schmidt EM, Foerster JR, Abecasis GR, Gray JC, de Wit H, Davis LK, MacKillop J, Palmer AA.

Nat Neurosci. 2019 Jan 8. doi: 10.1038/s41593-018-0306-y. [Epub ahead of print]


Changes in ontogenetic patterns facilitate diversification in skull shape of Australian agamid lizards.

Gray JA, Sherratt E, Hutchinson MN, Jones MEH.

BMC Evol Biol. 2019 Jan 8;19(1):7. doi: 10.1186/s12862-018-1335-6.


Plasma Cells are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease.

Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJ, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KE, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ.

Gastroenterology. 2018 Dec 26. pii: S0016-5085(18)35420-9. doi: 10.1053/j.gastro.2018.12.013. [Epub ahead of print]


Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer.

Chiappori AA, Williams CC, Gray JE, Tanvetyanon T, Haura EB, Creelan BC, Thapa R, Chen DT, Simon GR, Bepler G, Gabrilovich DI, Antonia SJ.

Cancer Immunol Immunother. 2018 Dec 27. doi: 10.1007/s00262-018-2287-9. [Epub ahead of print]


Personality traits share overlapping neuroanatomical correlates with internalizing and externalizing psychopathology.

Hyatt CS, Owens MM, Gray JC, Carter NT, MacKillop J, Sweet LH, Miller JD.

J Abnorm Psychol. 2019 Jan;128(1):1-11. doi: 10.1037/abn0000391. Epub 2018 Dec 27.


The WNT10B network is associated with survival and metastases in chemoresistant triple-negative breast cancer.

El Ayachi I, Fatima I, Wend P, Alva-Ornelas JA, Runke S, Kuenzinger WL, Silva J, Silva W, Gray JK, Lehr S, Barch HC, Krutilina RI, White AC, Cardiff R, Yee LD, Yang L, O'Regan RM, Lowry WE, Seagroves TN, Seewaldt V, Krum SA, Miranda-Carboni GA.

Cancer Res. 2018 Dec 18. pii: canres.1069.2018. doi: 10.1158/0008-5472.CAN-18-1069. [Epub ahead of print]


Ulcerated forehead nodule in an intravenous heroin user.

Schlessinger DI, Gray J, Speiser J, Lake E.

JAAD Case Rep. 2018 Dec 6;5(1):63-65. doi: 10.1016/j.jdcr.2018.10.008. eCollection 2019 Jan. No abstract available.


Implementing a comprehensive translational oncology platform: from molecular testing to actionability.

Mitri ZI, Parmar S, Johnson B, Kolodzie A, Keck JM, Morris M, Guimaraes AR, Beckett BR, Borate U, Lopez CD, Kemmer KA, Alumkal JJ, Beer TM, Corless CL, Mills GB, Gray JW, Bergan RC.

J Transl Med. 2018 Dec 14;16(1):358. doi: 10.1186/s12967-018-1733-y.


Preventing healthcare-associated infection by sharing research, evidence and best practice.

Gray J, Winzor G, Mahdia N, Oppenheim B, Johnston A.

J Hosp Infect. 2019 Feb;101(2):117-119. doi: 10.1016/j.jhin.2018.12.004. Epub 2018 Dec 12. No abstract available.


Feasibility of trial procedures for a randomised controlled trial of a community based group exercise intervention for falls prevention for visually impaired older people: the VIOLET study.

Adams N, Skelton DA, Howel D, Bailey C, Lampitt R, Fouweather T, Gray J, Coe D, Wilkinson J, Gawler S, de Jong LD, Waterman H, Deary V, Clarke M, Parry SW.

BMC Geriatr. 2018 Dec 12;18(1):307. doi: 10.1186/s12877-018-0998-6.


Cell-type-specific programs for activity-regulated gene expression.

Gray JM, Spiegel I.

Curr Opin Neurobiol. 2018 Dec 4;56:33-39. doi: 10.1016/j.conb.2018.11.001. [Epub ahead of print] Review.


Procedural sedation in children with autism spectrum disorders in the emergency department.

Brown JJ, Gray JM, Roback MG, Sethuraman U, Farooqi A, Kannikeswaran N.

Am J Emerg Med. 2018 Oct 16. pii: S0735-6757(18)30839-8. doi: 10.1016/j.ajem.2018.10.025. [Epub ahead of print]


Excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling.

Minnella AM, Zhao JX, Jiang X, Jakobsen E, Lu F, Wu L, El-Benna J, Gray JA, Swanson RA.

Sci Rep. 2018 Nov 30;8(1):17522. doi: 10.1038/s41598-018-35725-5.


Randomised controlled trial of cognitive behavioural therapy in COPD.

Heslop-Marshall K, Baker C, Carrick-Sen D, Newton J, Echevarria C, Stenton C, Jambon M, Gray J, Pearce K, Burns G, De Soyza A.

ERJ Open Res. 2018 Nov 23;4(4). pii: 00094-2018. doi: 10.1183/23120541.00094-2018. eCollection 2018 Oct.


Clinical associations of mucin 1 in human lung cancer and precancerous lesions.

Saltos A, Khalil F, Smith M, Li J, Schell M, Antonia SJ, Gray JE.

Oncotarget. 2018 Nov 2;9(86):35666-35675. doi: 10.18632/oncotarget.26278. eCollection 2018 Nov 2.


What initiatives do healthcare leaders agree are needed for healthcare system improvement? Results of a modified-Delphi study.

Barson S, Gauld R, Gray J, Henriks G, Krause C, Lachman P, Maher L, Massoud MR, Mathias L, Wagner M, Villa L.

J Health Organ Manag. 2018 Nov 19;32(8):1002-1012. doi: 10.1108/JHOM-08-2017-0216. Epub 2018 Nov 22.


Reconnaissance of Mixed Organic and Inorganic Chemicals in Private and Public Supply Tapwaters at Selected Residential and Workplace Sites in the United States.

Bradley PM, Kolpin DW, Romanok KM, Smalling KL, Focazio MJ, Brown JB, Cardon MC, Carpenter KD, Corsi SR, DeCicco LA, Dietze JE, Evans N, Furlong ET, Givens CE, Gray JL, Griffin DW, Higgins CP, Hladik ML, Iwanowicz LR, Journey CA, Kuivila KM, Masoner JR, McDonough CA, Meyer MT, Orlando JL, Strynar MJ, Weis CP, Wilson VS.

Environ Sci Technol. 2018 Nov 21. doi: 10.1021/acs.est.8b04622. [Epub ahead of print]


Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function.

Buchan SL, Dou L, Remer M, Booth SG, Dunn SN, Lai C, Semmrich M, Teige I, Mårtensson L, Penfold CA, Chan HTC, Willoughby JE, Mockridge CI, Dahal LN, Cleary KLS, James S, Rogel A, Kannisto P, Jernetz M, Williams EL, Healy E, Verbeek JS, Johnson PWM, Frendéus B, Cragg MS, Glennie MJ, Gray JC, Al-Shamkhani A, Beers SA.

Immunity. 2018 Nov 20;49(5):958-970.e7. doi: 10.1016/j.immuni.2018.09.014. Epub 2018 Nov 13.


Outbreak reports.

Gray J.

J Hosp Infect. 2018 Dec;100(4):481. doi: 10.1016/j.jhin.2018.10.018. No abstract available.


I-SceI Meganuclease-mediated transgenesis in the acorn worm, Saccoglossus kowalevskii.

Minor PJ, Clarke DN, Andrade López JM, Fritzenwanker JH, Gray J, Lowe CJ.

Dev Biol. 2019 Jan 1;445(1):8-15. doi: 10.1016/j.ydbio.2018.10.022. Epub 2018 Nov 6.


Changes in social networks are associated with lesbian, bisexual and queer women quitting smoking: An analysis of Australian survey data.

Kolstee J, Deacon RM, Haidar S, Gray J, Mooney-Somers J.

Drug Alcohol Rev. 2019 Jan;38(1):76-81. doi: 10.1111/dar.12873. Epub 2018 Nov 8.


Variability in antimicrobial use in pediatric ventilator-associated events.

Karandikar MV, Coffin SE, Priebe GP, Sandora TJ, Logan LK, Larsen GY, Toltzis P, Gray JE, Klompas M, Sammons JS, Harper MB, Horan K, Lakoma M, Cocoros NM, Lee GM.

Infect Control Hosp Epidemiol. 2019 Jan;40(1):32-39. doi: 10.1017/ice.2018.264. Epub 2018 Nov 9.


A woman in a man's world.

Gray J.

Clin Invest Med. 2018 Nov 3;41:32-24. doi: 10.25011/cim.v41i2.31437.


Musculoskeletal predictors of non-contact injury in cricketers - Few and far between? A longitudinal cohort study.

Olivier B, Gray J.

Phys Ther Sport. 2018 Nov;34:208-215. doi: 10.1016/j.ptsp.2018.10.014. Epub 2018 Oct 23.


Case Report: 28-year-old Woman With Opioid Use Disorder Delivers Healthy Baby While in Custody: Addressing Forced Detox.

Gray J, Saia K, Walley AY.

J Addict Med. 2018 Oct 30. doi: 10.1097/ADM.0000000000000468. [Epub ahead of print]


Machine-Learning-Assisted Many-Body Entanglement Measurement.

Gray J, Banchi L, Bayat A, Bose S.

Phys Rev Lett. 2018 Oct 12;121(15):150503. doi: 10.1103/PhysRevLett.121.150503.


Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution.

Cheng JB, Sedgewick AJ, Finnegan AI, Harirchian P, Lee J, Kwon S, Fassett MS, Golovato J, Gray M, Ghadially R, Liao W, Perez White BE, Mauro TM, Mully T, Kim EA, Sbitany H, Neuhaus IM, Grekin RC, Yu SS, Gray JW, Purdom E, Paus R, Vaske CJ, Benz SC, Song JS, Cho RJ.

Cell Rep. 2018 Oct 23;25(4):871-883. doi: 10.1016/j.celrep.2018.09.006.


Combined administration of anti-IL-13 and anti-IL-17A at individually sub-therapeutic doses limits asthma-like symptoms in a mouse model of Th2/Th17 high asthma.

Kim D, McAlees JW, Bischoff LJ, Kaur D, Houshel LK, Gray J, Hargis J, Davis X, Dudas PL, Deshmukh H, Lewkowich IP.

Clin Exp Allergy. 2018 Oct 24. doi: 10.1111/cea.13301. [Epub ahead of print]


A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.

Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, Labourel A, Trost M, Henrissat B, Gilbert HJ.

Nat Microbiol. 2018 Nov;3(11):1314-1326. doi: 10.1038/s41564-018-0258-8. Epub 2018 Oct 22.


Pre-orthodontic periodontal augmentation for lower incisor advancement in adolescent patients.

Gray JB, Richman C.

J Clin Orthod. 2018 Oct;52(10):513-527. No abstract available.


Three-dimensional shape and velocity changes affect responses of a locust visual interneuron to approaching objects.

Stott TP, Olson EGN, Parkinson RH, Gray JR.

J Exp Biol. 2018 Dec 10;221(Pt 24). pii: jeb191320. doi: 10.1242/jeb.191320.


Impact of HACA on Immunomodulation and Treatment Toxicity Following ch14.18/CHO Long-Term Infusion with Interleukin-2: Results from a SIOPEN Phase 2 Trial.

Siebert N, Troschke-Meurer S, Marx M, Zumpe M, Ehlert K, Gray J, Garaventa A, Manzitti C, Ash S, Klingebiel T, Beck J, Castel V, Valteau-Couanet D, Loibner H, Ladenstein R, Lode HN.

Cancers (Basel). 2018 Oct 17;10(10). pii: E387. doi: 10.3390/cancers10100387.


Challenges of Compassionate Conservation.

Gray J.

J Appl Anim Welf Sci. 2018;21(sup1):34-42. doi: 10.1080/10888705.2018.1513840.


Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.

Chandra S, Gray J, Kiosses WB, Khurana A, Hitomi K, Crosby CM, Chawla A, Fu Z, Zhao M, Veerapen N, Richardson SK, Porcelli SA, Besra G, Howell AR, Sharma S, Peters B, Kronenberg M.

Nat Commun. 2018 Oct 15;9(1):4279. doi: 10.1038/s41467-018-06646-8.


Sex Differences in the Rat Hippocampal Opioid System After Oxycodone Conditioned Place Preference.

Ryan JD, Zhou Y, Contoreggi NH, Bshesh FK, Gray JD, Kogan JF, Ben KT, McEwen BS, Jeanne Kreek M, Milner TA.

Neuroscience. 2018 Nov 21;393:236-257. doi: 10.1016/j.neuroscience.2018.10.002. Epub 2018 Oct 11.


Emergency department checklist: an innovation to improve safety in emergency care.

Redfern E, Hoskins R, Gray J, Lugg J, Hastie A, Clark C, Benger J.

BMJ Open Qual. 2018 Sep 26;7(3):e000325. doi: 10.1136/bmjoq-2018-000325. eCollection 2018. No abstract available.

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