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Items: 38

1.

Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues.

Graves PR, Aponte-Collazo LJ, Fennell EMJ, Graves AC, Hale AE, Dicheva N, Herring LE, Gilbert TSK, East MP, McDonald IM, Lockett MR, Ashamalla H, Moorman NJ, Karanewsky DS, Iwanowicz EJ, Holmuhamedov E, Graves LM.

ACS Chem Biol. 2019 May 17;14(5):1020-1029. doi: 10.1021/acschembio.9b00222. Epub 2019 May 1.

2.

Ionizing radiation induces EphA2 S897 phosphorylation in a MEK/ERK/RSK-dependent manner.

Graves PR, Din SU, Ashamalla M, Ashamalla H, Gilbert TSK, Graves LM.

Int J Radiat Biol. 2017 Sep;93(9):929-936. doi: 10.1080/09553002.2017.1355580.

PMID:
28705041
3.

Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins.

Bridge KS, Shah KM, Li Y, Foxler DE, Wong SCK, Miller DC, Davidson KM, Foster JG, Rose R, Hodgkinson MR, Ribeiro PS, Aboobaker AA, Yashiro K, Wang X, Graves PR, Plevin MJ, Lagos D, Sharp TV.

Cell Rep. 2017 Jul 5;20(1):173-187. doi: 10.1016/j.celrep.2017.06.027.

4.

Mutant p53 and the response to chemotherapy and radiation.

Tchelebi L, Ashamalla H, Graves PR.

Subcell Biochem. 2014;85:133-59. doi: 10.1007/978-94-017-9211-0_8. Review.

PMID:
25201193
5.

Identification of novel mutant p53 interacting proteins by proteomic analysis.

Deb S, Graves PR.

Methods Mol Biol. 2013;962:85-94. doi: 10.1007/978-1-62703-236-0_7.

PMID:
23150439
6.

p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity.

Vaughan CA, Singh S, Windle B, Sankala HM, Graves PR, Andrew Yeudall W, Deb SP, Deb S.

Arch Biochem Biophys. 2012 Feb 1;518(1):79-88. doi: 10.1016/j.abb.2011.12.006. Epub 2011 Dec 16.

7.

Upregulation of the mitochondrial transport protein, Tim50, by mutant p53 contributes to cell growth and chemoresistance.

Sankala H, Vaughan C, Wang J, Deb S, Graves PR.

Arch Biochem Biophys. 2011 Aug 1;512(1):52-60. doi: 10.1016/j.abb.2011.05.005. Epub 2011 May 20.

8.

Factors influencing protein tyrosine nitration--structure-based predictive models.

Bayden AS, Yakovlev VA, Graves PR, Mikkelsen RB, Kellogg GE.

Free Radic Biol Med. 2011 Mar 15;50(6):749-62. doi: 10.1016/j.freeradbiomed.2010.12.016. Epub 2010 Dec 21.

9.

Radiation pulmonary toxicity: from mechanisms to management.

Graves PR, Siddiqui F, Anscher MS, Movsas B.

Semin Radiat Oncol. 2010 Jul;20(3):201-7. doi: 10.1016/j.semradonc.2010.01.010. Review.

PMID:
20685583
10.

Proteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP(5+).

Yakovlev VA, Rabender CS, Sankala H, Gauter-Fleckenstein B, Fleckenstein K, Batinic-Haberle I, Jackson I, Vujaskovic Z, Anscher MS, Mikkelsen RB, Graves PR.

Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):547-54. doi: 10.1016/j.ijrobp.2010.03.037. Epub 2010 Jun 30.

11.

Nitration of the tumor suppressor protein p53 at tyrosine 327 promotes p53 oligomerization and activation.

Yakovlev VA, Bayden AS, Graves PR, Kellogg GE, Mikkelsen RB.

Biochemistry. 2010 Jun 29;49(25):5331-9. doi: 10.1021/bi100564w.

12.

Stable Argonaute2 overexpression differentially regulates microRNA production.

Zhang X, Graves PR, Zeng Y.

Biochim Biophys Acta. 2009 Feb;1789(2):153-9. doi: 10.1016/j.bbagrm.2008.11.004. Epub 2008 Nov 21.

PMID:
19064005
13.

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies.

Zeng Y, Sankala H, Zhang X, Graves PR.

Biochem J. 2008 Aug 1;413(3):429-36. doi: 10.1042/BJ20080599.

PMID:
18476811
14.

Tyrosine nitration of IkappaBalpha: a novel mechanism for NF-kappaB activation.

Yakovlev VA, Barani IJ, Rabender CS, Black SM, Leach JK, Graves PR, Kellogg GE, Mikkelsen RB.

Biochemistry. 2007 Oct 23;46(42):11671-83. Epub 2007 Oct 2.

15.

Regulation of human cytidine triphosphate synthetase 1 by glycogen synthase kinase 3.

Higgins MJ, Graves PR, Graves LM.

J Biol Chem. 2007 Oct 5;282(40):29493-503. Epub 2007 Aug 6.

16.

Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes.

Walker JR, Gnanam AJ, Blinkova AL, Hermandson MJ, Karymov MA, Lyubchenko YL, Graves PR, Haystead TA, Linse KD.

Mol Microbiol. 2007 Feb;63(3):629-43.

17.

Understanding mitochondrial genetic abnormalities in cancer etiology: a proteomics approach.

Graves PR.

Cancer Biol Ther. 2006 Aug;5(8):976-7. Epub 2006 Aug 21. No abstract available.

PMID:
16969084
18.

Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation.

Graves PR, Winkfield KM, Haystead TA.

J Biol Chem. 2005 Mar 11;280(10):9363-74. Epub 2004 Dec 20. Erratum in: J Biol Chem. 2005 Jun 17;280(24):23424.

19.

A functional proteomics approach to signal transduction.

Graves PR, Haystead TA.

Recent Prog Horm Res. 2003;58:1-24. Review.

PMID:
12795412
20.

Discovery of novel targets of quinoline drugs in the human purine binding proteome.

Graves PR, Kwiek JJ, Fadden P, Ray R, Hardeman K, Coley AM, Foley M, Haystead TA.

Mol Pharmacol. 2002 Dec;62(6):1364-72.

PMID:
12435804
21.

Molecular biologist's guide to proteomics.

Graves PR, Haystead TA.

Microbiol Mol Biol Rev. 2002 Mar;66(1):39-63; table of contents. Review.

22.

The human decatenation checkpoint.

Deming PB, Cistulli CA, Zhao H, Graves PR, Piwnica-Worms H, Paules RS, Downes CS, Kaufmann WK.

Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12044-9. Epub 2001 Oct 2.

23.

Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

Graves PR, Lovly CM, Uy GL, Piwnica-Worms H.

Oncogene. 2001 Apr 5;20(15):1839-51.

24.

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01.

Graves PR, Yu L, Schwarz JK, Gales J, Sausville EA, O'Connor PM, Piwnica-Worms H.

J Biol Chem. 2000 Feb 25;275(8):5600-5.

25.

14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity.

Thorson JA, Yu LW, Hsu AL, Shih NY, Graves PR, Tanner JW, Allen PM, Piwnica-Worms H, Shaw AS.

Mol Cell Biol. 1998 Sep;18(9):5229-38.

26.

C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding.

Peng CY, Graves PR, Ogg S, Thoma RS, Byrnes MJ 3rd, Wu Z, Stephenson MT, Piwnica-Worms H.

Cell Growth Differ. 1998 Mar;9(3):197-208.

27.

Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein.

Zhang SH, Kobayashi R, Graves PR, Piwnica-Worms H, Tonks NK.

J Biol Chem. 1997 Oct 24;272(43):27281-7.

28.

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.

Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H.

Science. 1997 Sep 5;277(5331):1501-5.

29.

Role of COOH-terminal phosphorylation in the regulation of casein kinase I delta.

Graves PR, Roach PJ.

J Biol Chem. 1995 Sep 15;270(37):21689-94.

30.

Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes.

Zhai L, Graves PR, Robinson LC, Italiano M, Culbertson MR, Rowles J, Cobb MH, DePaoli-Roach AA, Roach PJ.

J Biol Chem. 1995 May 26;270(21):12717-24.

31.

Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis.

Graves PR, Haas DW, Hagedorn CH, DePaoli-Roach AA, Roach PJ.

J Biol Chem. 1993 Mar 25;268(9):6394-401.

32.

Recombinant rabbit muscle casein kinase I alpha is inhibited by heparin and activated by polylysine.

Zhai L, Graves PR, Longenecker KL, DePaoli-Roach AA, Roach PJ.

Biochem Biophys Res Commun. 1992 Dec 15;189(2):944-9.

PMID:
1472067
33.

Yeast casein kinase I homologues: an essential gene pair.

Robinson LC, Hubbard EJ, Graves PR, DePaoli-Roach AA, Roach PJ, Kung C, Haas DW, Hagedorn CH, Goebl M, Culbertson MR, et al.

Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):28-32.

34.

Glycogen metabolism and signal transduction in mammals and yeast.

Roach PJ, Cao Y, Corbett CA, DePaoli-Roach AA, Farkas I, Fiol CJ, Flotow H, Graves PR, Hardy TA, Hrubey TW, et al.

Adv Enzyme Regul. 1991;31:101-20. Review.

PMID:
1652188
35.

Phosphate groups as substrate determinants for casein kinase I action.

Flotow H, Graves PR, Wang AQ, Fiol CJ, Roeske RW, Roach PJ.

J Biol Chem. 1990 Aug 25;265(24):14264-9.

36.

Recovery from Ruptured Mycotic Aneurysm.

Graves PR, Russell IJ.

Br Med J. 1950 Apr 1;1(4656):768-9. No abstract available.

37.

Three cases of agranulocytosis.

GRAVES PR.

Br Med J. 1947 Apr 12;1(4501):490. No abstract available.

38.

Pellagrous encephalography.

GRAVES PR.

Br Med J. 1947 Feb 15;1(4493):253-6. No abstract available.

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