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Items: 1 to 50 of 66

1.

Antitumoral effects of attenuated Listeria monocytogenes in a genetically engineered mouse model of melanoma.

Vitiello M, Evangelista M, Di Lascio N, Kusmic C, Massa A, Orso F, Sarti S, Marranci A, Rodzik K, Germelli L, Chandra D, Salvetti A, Pucci A, Taverna D, Faita F, Gravekamp C, Poliseno L.

Oncogene. 2019 May;38(19):3756-3762. doi: 10.1038/s41388-019-0681-1. Epub 2019 Jan 21.

2.

Tumour-targeting bacteria engineered to fight cancer.

Zhou S, Gravekamp C, Bermudes D, Liu K.

Nat Rev Cancer. 2018 Dec;18(12):727-743. doi: 10.1038/s41568-018-0070-z. Review.

PMID:
30405213
3.

White paper on microbial anti-cancer therapy and prevention.

Forbes NS, Coffin RS, Deng L, Evgin L, Fiering S, Giacalone M, Gravekamp C, Gulley JL, Gunn H, Hoffman RM, Kaur B, Liu K, Lyerly HK, Marciscano AE, Moradian E, Ruppel S, Saltzman DA, Tattersall PJ, Thorne S, Vile RG, Zhang HH, Zhou S, McFadden G.

J Immunother Cancer. 2018 Aug 6;6(1):78. doi: 10.1186/s40425-018-0381-3.

4.

Immunotherapy with Listeria reduces metastatic breast cancer in young and old mice through different mechanisms.

Jahangir A, Chandra D, Quispe-Tintaya W, Singh M, Selvanesan BC, Gravekamp C.

Oncoimmunology. 2017 Jul 5;6(9):e1342025. doi: 10.1080/2162402X.2017.1342025. eCollection 2017.

5.

A Radiolabeled Fully Human Antibody to Human Aspartyl (Asparaginyl) β-Hydroxylase Is a Promising Agent for Imaging and Therapy of Metastatic Breast Cancer.

Revskaya E, Jiang Z, Morgenstern A, Bruchertseifer F, Sesay M, Walker S, Fuller S, Lebowitz MS, Gravekamp C, Ghanbari HA, Dadachova E.

Cancer Biother Radiopharm. 2017 Mar;32(2):57-65. doi: 10.1089/cbr.2016.2141.

6.

32-Phosphorus selectively delivered by listeria to pancreatic cancer demonstrates a strong therapeutic effect.

Chandra D, Selvanesan BC, Yuan Z, Libutti SK, Koba W, Beck A, Zhu K, Casadevall A, Dadachova E, Gravekamp C.

Oncotarget. 2017 Mar 28;8(13):20729-20740. doi: 10.18632/oncotarget.15117.

7.

Reverse geroscience: how does exposure to early diseases accelerate the age-related decline in health?

Kohanski RA, Deeks SG, Gravekamp C, Halter JB, High K, Hurria A, Fuldner R, Green P, Huebner R, Macchiarini F, Sierra F.

Ann N Y Acad Sci. 2016 Dec;1386(1):30-44. doi: 10.1111/nyas.13297. Epub 2016 Dec 1. Review.

8.

Cryoablation and Meriva have strong therapeutic effect on triple-negative breast cancer.

Chandra D, Jahangir A, Cornelis F, Rombauts K, Meheus L, Jorcyk CL, Gravekamp C.

Oncoimmunology. 2015 May 29;5(1):e1049802. eCollection 2016.

9.

In vitro and in vivo investigations on the antitumour activity of Chelidonium majus.

Capistrano I R, Wouters A, Lardon F, Gravekamp C, Apers S, Pieters L.

Phytomedicine. 2015 Dec 15;22(14):1279-87. doi: 10.1016/j.phymed.2015.10.013. Epub 2015 Nov 10.

PMID:
26626193
10.

Targeting STING pathways for the treatment of cancer.

Gravekamp C, Chandra D.

Oncoimmunology. 2015 Jan 7;4(12):e988463. eCollection 2015 Dec.

11.

Targeted radionuclide therapies for pancreatic cancer.

Shah M, Da Silva R, Gravekamp C, Libutti SK, Abraham T, Dadachova E.

Cancer Gene Ther. 2015 Aug;22(8):375-9. doi: 10.1038/cgt.2015.32. Epub 2015 Jul 31. Review.

12.

Characterization and assessment of nanoencapsulated sanguinarine chloride as a potential treatment for melanoma.

Rosen J, Landriscina A, Adler BL, Krauz A, Doerner J, Navati M, Musaev T, Gravekamp C, Nosanchuk J, Friedman AJ.

J Drugs Dermatol. 2015 May;14(5):453-8.

PMID:
25942662
13.

Direct incorporation of the NKT-cell activator α-galactosylceramide into a recombinant Listeria monocytogenes improves breast cancer vaccine efficacy.

Singh M, Quispe-Tintaya W, Chandra D, Jahangir A, Venkataswamy MM, Ng TW, Sharma-Kharkwal S, Carreño LJ, Porcelli SA, Gravekamp C.

Br J Cancer. 2014 Nov 11;111(10):1945-54. doi: 10.1038/bjc.2014.486. Epub 2014 Oct 14.

14.

Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation.

Valdor R, Mocholi E, Botbol Y, Guerrero-Ros I, Chandra D, Koga H, Gravekamp C, Cuervo AM, Macian F.

Nat Immunol. 2014 Nov;15(11):1046-54. doi: 10.1038/ni.3003. Epub 2014 Sep 28.

15.

STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer.

Chandra D, Quispe-Tintaya W, Jahangir A, Asafu-Adjei D, Ramos I, Sintim HO, Zhou J, Hayakawa Y, Karaolis DK, Gravekamp C.

Cancer Immunol Res. 2014 Sep;2(9):901-10. doi: 10.1158/2326-6066.CIR-13-0123. Epub 2014 Jun 9.

16.

Is cancer vaccination feasible at older age?

Gravekamp C, Jahangir A.

Exp Gerontol. 2014 Jun;54:138-44. doi: 10.1016/j.exger.2014.01.025. Epub 2014 Feb 6. Review.

17.

Myeloid-derived suppressor cells: Cellular missiles to target tumors.

Chandra D, Gravekamp C.

Oncoimmunology. 2013 Nov 1;2(11):e26967. Epub 2013 Nov 6. Review.

18.

Curcumin improves the therapeutic efficacy of Listeria(at)-Mage-b vaccine in correlation with improved T-cell responses in blood of a triple-negative breast cancer model 4T1.

Singh M, Ramos I, Asafu-Adjei D, Quispe-Tintaya W, Chandra D, Jahangir A, Zang X, Aggarwal BB, Gravekamp C.

Cancer Med. 2013 Aug;2(4):571-82. doi: 10.1002/cam4.94. Epub 2013 Jul 2.

19.

Myeloid-derived suppressor cells have a central role in attenuated Listeria monocytogenes-based immunotherapy against metastatic breast cancer in young and old mice.

Chandra D, Jahangir A, Quispe-Tintaya W, Einstein MH, Gravekamp C.

Br J Cancer. 2013 Jun 11;108(11):2281-90. doi: 10.1038/bjc.2013.206. Epub 2013 May 2.

20.

Nontoxic radioactive Listeria(at) is a highly effective therapy against metastatic pancreatic cancer.

Quispe-Tintaya W, Chandra D, Jahangir A, Harris M, Casadevall A, Dadachova E, Gravekamp C.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8668-73. doi: 10.1073/pnas.1211287110. Epub 2013 Apr 22.

21.

Cancer vaccination at older age.

Gravekamp C.

Interdiscip Top Gerontol. 2013;38:28-37. doi: 10.1159/000343596. Epub 2013 Jan 25. Review.

22.

Host b7x promotes pulmonary metastasis of breast cancer.

Abadi YM, Jeon H, Ohaegbulam KC, Scandiuzzi L, Ghosh K, Hofmeyer KA, Lee JS, Ray A, Gravekamp C, Zang X.

J Immunol. 2013 Apr 1;190(7):3806-14. doi: 10.4049/jimmunol.1202439. Epub 2013 Mar 1.

23.

Aging and cancer vaccines.

Gravekamp C, Chandra D.

Crit Rev Oncog. 2013;18(6):585-95. Review.

24.

The impact of aging on cancer vaccination.

Gravekamp C.

Curr Opin Immunol. 2011 Aug;23(4):555-60. doi: 10.1016/j.coi.2011.05.003. Epub 2011 Jul 18. Review.

25.

Harnessing Listeria monocytogenes to target tumors.

Gravekamp C, Paterson Y.

Cancer Biol Ther. 2010 Feb;9(4):257-65. doi: 10.4161/cbt.9.4.11216. Epub 2010 Feb 1. Review.

26.

Vaccination with Mage-b DNA induces CD8 T-cell responses at young but not old age in mice with metastatic breast cancer.

Castro F, Leal B, Denny A, Bahar R, Lampkin S, Reddick R, Lu S, Gravekamp C.

Br J Cancer. 2009 Oct 20;101(8):1329-37. doi: 10.1038/sj.bjc.6605329. Epub 2009 Sep 29.

27.

Impact of aging on cancer immunity and immunotherapy.

Pawelec G, Lustgarten J, Ruby C, Gravekamp C.

Cancer Immunol Immunother. 2009 Dec;58(12):1907-8. No abstract available.

PMID:
19787858
28.

High efficacy of a Listeria-based vaccine against metastatic breast cancer reveals a dual mode of action.

Kim SH, Castro F, Paterson Y, Gravekamp C.

Cancer Res. 2009 Jul 15;69(14):5860-6. doi: 10.1158/0008-5472.CAN-08-4855. Epub 2009 Jul 7.

29.

The importance of the age factor in cancer vaccination at older age.

Gravekamp C.

Cancer Immunol Immunother. 2009 Dec;58(12):1969-77. doi: 10.1007/s00262-009-0683-x. Epub 2009 Mar 4. Review.

30.

Mage-b vaccine delivered by recombinant Listeria monocytogenes is highly effective against breast cancer metastases.

Kim SH, Castro F, Gonzalez D, Maciag PC, Paterson Y, Gravekamp C.

Br J Cancer. 2008 Sep 2;99(5):741-9. doi: 10.1038/sj.bjc.6604526. Epub 2008 Aug 19.

31.

Cancer vaccination: manipulation of immune responses at old age.

Gravekamp C, Kim SH, Castro F.

Mech Ageing Dev. 2009 Jan-Feb;130(1-2):67-75. doi: 10.1016/j.mad.2008.05.003. Epub 2008 May 9. Review.

PMID:
18561984
32.

In vivo responses to vaccination with Mage-b, GM-CSF and thioglycollate in a highly metastatic mouse breast tumor model, 4T1.

Gravekamp C, Leal B, Denny A, Bahar R, Lampkin S, Castro F, Kim SH, Moore D, Reddick R.

Cancer Immunol Immunother. 2008 Jul;57(7):1067-77.

PMID:
18094967
33.

MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines.

Yang B, O'Herrin SM, Wu J, Reagan-Shaw S, Ma Y, Bhat KM, Gravekamp C, Setaluri V, Peters N, Hoffmann FM, Peng H, Ivanov AV, Simpson AJ, Longley BJ.

Cancer Res. 2007 Oct 15;67(20):9954-62.

34.

Cancer vaccines in old age.

Gravekamp C.

Exp Gerontol. 2007 May;42(5):441-50. Epub 2007 Jan 2. Review.

35.

Prevention of metastases with a Mage-b DNA vaccine in a mouse breast tumor model: potential for breast cancer therapy.

Sypniewska RK, Hoflack L, Tarango M, Gauntt S, Leal BZ, Reddick RL, Gravekamp C.

Breast Cancer Res Treat. 2005 May;91(1):19-28.

PMID:
15868428
36.

Behavior of metastatic and nonmetastatic breast tumors in old mice.

Gravekamp C, Sypniewska R, Gauntt S, Tarango M, Price P, Reddick R.

Exp Biol Med (Maywood). 2004 Jul;229(7):665-75.

PMID:
15229361
37.

The usefulness of mouse breast tumor models for testing and optimization of breast cancer vaccines at old age.

Gravekamp C, Sypniewska R, Hoflack L.

Mech Ageing Dev. 2004 Feb;125(2):125-7. Review.

PMID:
15037016
38.

Direct detection of leptospiral material in human postmortem samples.

Brown PD, Carrington DG, Gravekamp C, van de Kemp H, Edwards CN, Jones SR, Prussia PR, Garriques S, Terpstra WJ, Levett PN.

Res Microbiol. 2003 Oct;154(8):581-6.

PMID:
14527659
39.

The alpha C protein mediates internalization of group B Streptococcus within human cervical epithelial cells.

Bolduc GR, Baron MJ, Gravekamp C, Lachenauer CS, Madoff LC.

Cell Microbiol. 2002 Nov;4(11):751-8.

PMID:
12427097
40.

Potential mouse tumor model for pre-clinical testing of mage-specific breast cancer vaccines.

Sypniewska RK, Hoflack L, Bearss DJ, Gravekamp C.

Breast Cancer Res Treat. 2002 Jun;74(3):221-33.

PMID:
12211215
41.

Quantitative determination of immunoglobulin G specific for group B streptococcal beta C protein in human maternal serum.

Lachenauer CS, Baker CJ, Baron MJ, Kasper DL, Gravekamp C, Madoff LC.

J Infect Dis. 2002 Feb 1;185(3):368-74. Epub 2002 Jan 17.

PMID:
11807719
42.

Tailoring cancer vaccines to the elderly: the importance of suitable mouse models.

Gravekamp C.

Mech Ageing Dev. 2001 Aug;122(11):1087-105. Review.

PMID:
11389926
43.
44.
45.

Immunogenicity and protective efficacy of the alpha C protein of group B streptococci are inversely related to the number of repeats.

Gravekamp C, Kasper DL, Michel JL, Kling DE, Carey V, Madoff LC.

Infect Immun. 1997 Dec;65(12):5216-21.

46.
47.

Immunization with a single-repeat alpha C protein may prevent escape of lower repeat mutants of group B Streptococcus.

Gravekamp C, Kasper DL, Madoff LC.

Adv Exp Med Biol. 1997;418:855-7. No abstract available.

PMID:
9331787
48.
49.

Evaluation of the polymerase chain reaction for early diagnosis of leptospirosis.

Brown PD, Gravekamp C, Carrington DG, van de Kemp H, Hartskeerl RA, Edwards CN, Everard CO, Terpstra WJ, Levett PN.

J Med Microbiol. 1995 Aug;43(2):110-4.

PMID:
7629850
50.

Detection of leptospires in urine by PCR for early diagnosis of leptospirosis.

Bal AE, Gravekamp C, Hartskeerl RA, De Meza-Brewster J, Korver H, Terpstra WJ.

J Clin Microbiol. 1994 Aug;32(8):1894-8.

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