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Items: 1 to 50 of 51

1.

Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.

Iring A, Jin YJ, Albarrán-Juárez J, Siragusa M, Wang S, Dancs PT, Nakayama A, Tonack S, Chen M, Künne C, Sokol AM, Günther S, Martínez A, Fleming I, Wettschureck N, Graumann J, Weinstein LS, Offermanns S.

J Clin Invest. 2019 Jun 17;130. pii: 123825. doi: 10.1172/JCI123825. eCollection 2019 Jun 17.

2.

Small-molecule-mediated chemical knock-down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure.

Adams V, Bowen TS, Werner S, Barthel P, Amberger C, Konzer A, Graumann J, Sehr P, Lewis J, Provaznik J, Benes V, Büttner P, Gasch A, Mangner N, Witt CC, Labeit D, Linke A, Labeit S.

J Cachexia Sarcopenia Muscle. 2019 May 29. doi: 10.1002/jcsm.12448. [Epub ahead of print]

3.

MARMoSET - Extracting Publication-Ready Mass Spectrometry Metadata from RAW Files.

Kiweler M, Looso M, Graumann J.

Mol Cell Proteomics. 2019 May 16. pii: mcp.TIR119.001505. doi: 10.1074/mcp.TIR119.001505. [Epub ahead of print]

4.

Remodeling of ER-plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis.

Yu F, Hubrack SZ, Chakraborty S, Sun L, Alcantara-Adap E, Kulkarni R, Billing AM, Graumann J, Taylor CW, Machaca K.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10392-10401. doi: 10.1073/pnas.1821399116. Epub 2019 May 7.

5.

Correction: Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.

Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A.

PLoS Genet. 2019 Jan 31;15(1):e1007972. doi: 10.1371/journal.pgen.1007972. eCollection 2019 Jan.

6.

Characterization of mast cell-derived rRNA-containing microvesicles and their inflammatory impact on endothelial cells.

Elsemüller AK, Tomalla V, Gärtner U, Troidl K, Jeratsch S, Graumann J, Baal N, Hackstein H, Lasch M, Deindl E, Preissner KT, Fischer S.

FASEB J. 2019 Apr;33(4):5457-5467. doi: 10.1096/fj.201801853RR. Epub 2019 Jan 31.

PMID:
30702929
7.

Metabolic and proteomic signatures of hypoglycaemia in type 2 diabetes.

Halama A, Kahal H, Bhagwat AM, Zierer J, Sathyapalan T, Graumann J, Suhre K, Atkin SL.

Diabetes Obes Metab. 2018 Dec 7. doi: 10.1111/dom.13602. [Epub ahead of print]

PMID:
30525282
8.

Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists.

Mullapudi ST, Helker CS, Boezio GL, Maischein HM, Sokol AM, Guenther S, Matsuda H, Kubicek S, Graumann J, Yang YHC, Stainier DY.

Elife. 2018 Dec 6;7. pii: e42209. doi: 10.7554/eLife.42209.

9.

Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish.

Sokol AM, Uszczynska-Ratajczak B, Collins MM, Bazala M, Topf U, Lundegaard PR, Sugunan S, Guenther S, Kuenne C, Graumann J, Chan SSL, Stainier DYR, Chacinska A.

PLoS Genet. 2018 Nov 20;14(11):e1007743. doi: 10.1371/journal.pgen.1007743. eCollection 2018 Nov. Erratum in: PLoS Genet. 2019 Jan 31;15(1):e1007972.

10.

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR.

Nat Commun. 2018 Nov 2;9(1):4600. doi: 10.1038/s41467-018-06833-7.

11.

Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment.

Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R.

Mol Oncol. 2019 Feb;13(2):185-201. doi: 10.1002/1878-0261.12396. Epub 2018 Nov 15.

12.

The CCT chaperonin is a novel regulator of Ca2+ signaling through modulation of Orai1 trafficking.

Hodeify R, Nandakumar M, Own M, Courjaret RJ, Graumann J, Hubrack SZ, Machaca K.

Sci Adv. 2018 Sep 26;4(9):eaau1935. doi: 10.1126/sciadv.aau1935. eCollection 2018 Sep.

13.

Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D.

Nat Commun. 2018 Sep 18;9(1):3853. doi: 10.1038/s41467-018-06231-z.

14.

Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D.

Nat Commun. 2018 Aug 15;9(1):3268. doi: 10.1038/s41467-018-05512-x. Erratum in: Nat Commun. 2018 Sep 18;9(1):3853.

15.

MiCEE is a ncRNA-protein complex that mediates epigenetic silencing and nucleolar organization.

Singh I, Contreras A, Cordero J, Rubio K, Dobersch S, Günther S, Jeratsch S, Mehta A, Krüger M, Graumann J, Seeger W, Dobreva G, Braun T, Barreto G.

Nat Genet. 2018 Jul;50(7):990-1001. doi: 10.1038/s41588-018-0139-3. Epub 2018 Jun 4.

PMID:
29867223
16.

The VLDL receptor regulates membrane progesterone receptor trafficking and non-genomic signaling.

Nader N, Dib M, Courjaret R, Hodeify R, Machaca R, Graumann J, Machaca K.

J Cell Sci. 2018 May 23;131(10). pii: jcs212522. doi: 10.1242/jcs.212522.

17.

Proteomic profiling of human cancer pseudopodia for the identification of anti-metastatic drug candidates.

Choi S, Bhagwat AM, Al Mismar R, Goswami N, Ben Hamidane H, Sun L, Graumann J.

Sci Rep. 2018 Apr 11;8(1):5858. doi: 10.1038/s41598-018-24256-8.

18.

Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.

Zaghlool SB, Mook-Kanamori DO, Kader S, Stephan N, Halama A, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Roemisch-Margl W, Adamski J, Kastenmüller G, Friedrich N, Visconti A, Tsai PC, Spector T, Bell JT, Falchi M, Wahl A, Waldenberger M, Peters A, Gieger C, Pezer M, Lauc G, Graumann J, Malek JA, Suhre K.

Hum Mol Genet. 2018 Mar 15;27(6):1106-1121. doi: 10.1093/hmg/ddy006.

19.

Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment.

Worzfeld T, Finkernagel F, Reinartz S, Konzer A, Adhikary T, Nist A, Stiewe T, Wagner U, Looso M, Graumann J, Müller R.

Mol Cell Proteomics. 2018 Feb;17(2):270-289. doi: 10.1074/mcp.RA117.000400. Epub 2017 Nov 15.

20.

Using hESCs to Probe the Interaction of the Diabetes-Associated Genes CDKAL1 and MT1E.

Guo M, Zhang T, Dong X, Xiang JZ, Lei M, Evans T, Graumann J, Chen S.

Cell Rep. 2017 May 23;19(8):1512-1521. doi: 10.1016/j.celrep.2017.04.070.

21.

Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome.

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J.

Nat Commun. 2017 Apr 11;8:15345. doi: 10.1038/ncomms15345. No abstract available.

22.

flippant-An R package for the automated analysis of fluorescence-based scramblase assays.

Cotton RJ, Ploier B, Goren MA, Menon AK, Graumann J.

BMC Bioinformatics. 2017 Mar 3;18(1):146. doi: 10.1186/s12859-017-1542-y.

23.

Connecting genetic risk to disease end points through the human blood plasma proteome.

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J.

Nat Commun. 2017 Feb 27;8:14357. doi: 10.1038/ncomms14357.

24.

Complementarity of SOMAscan to LC-MS/MS and RNA-seq for quantitative profiling of human embryonic and mesenchymal stem cells.

Billing AM, Ben Hamidane H, Bhagwat AM, Cotton RJ, Dib SS, Kumar P, Hayat S, Goswami N, Suhre K, Rafii A, Graumann J.

J Proteomics. 2017 Jan 6;150:86-97. doi: 10.1016/j.jprot.2016.08.023. Epub 2016 Sep 6.

25.

The arc of Mass Spectrometry Exchange Formats is long, but it bends toward HDF5.

Askenazi M, Ben Hamidane H, Graumann J.

Mass Spectrom Rev. 2017 Sep;36(5):668-673. doi: 10.1002/mas.21522. Epub 2016 Oct 14. Review.

26.

Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants.

Ploier B, Caro LN, Morizumi T, Pandey K, Pearring JN, Goren MA, Finnemann SC, Graumann J, Arshavsky VY, Dittman JS, Ernst OP, Menon AK.

Nat Commun. 2016 Oct 3;7:12832. doi: 10.1038/ncomms12832.

27.

An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery.

Zeng H, Guo M, Zhou T, Tan L, Chong CN, Zhang T, Dong X, Xiang JZ, Yu AS, Yue L, Qi Q, Evans T, Graumann J, Chen S.

Cell Stem Cell. 2016 Sep 1;19(3):326-40. doi: 10.1016/j.stem.2016.07.002. Epub 2016 Aug 11.

28.

MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells.

Graham B, Marcais A, Dharmalingam G, Carroll T, Kanellopoulou C, Graumann J, Nesterova TB, Bermange A, Brazauskas P, Xella B, Kriaucionis S, Higgs DR, Brockdorff N, Mann M, Fisher AG, Merkenschlager M.

Stem Cell Reports. 2016 May 10;6(5):635-642. doi: 10.1016/j.stemcr.2016.03.005. Epub 2016 Apr 14.

29.

readat: An R package for reading and working with SomaLogic ADAT files.

Cotton RJ, Graumann J.

BMC Bioinformatics. 2016 May 4;17(1):201. doi: 10.1186/s12859-016-1007-8.

30.

Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers.

Billing AM, Ben Hamidane H, Dib SS, Cotton RJ, Bhagwat AM, Kumar P, Hayat S, Yousri NA, Goswami N, Suhre K, Rafii A, Graumann J.

Sci Rep. 2016 Feb 9;6:21507. doi: 10.1038/srep21507.

31.

SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition.

Abdesselem H, Madani A, Hani A, Al-Noubi M, Goswami N, Ben Hamidane H, Billing AM, Pasquier J, Bonkowski MS, Halabi N, Dalloul R, Sheriff MZ, Mesaeli N, ElRayess M, Sinclair DA, Graumann J, Mazloum NA.

J Biol Chem. 2016 Jan 29;291(5):2119-35. doi: 10.1074/jbc.M115.675645. Epub 2015 Dec 11.

32.

Quantitative proteomic approaches in mouse: stable isotope incorporation by metabolic (SILAC) or chemical labeling (reductive dimethylation) combined with high-resolution mass spectrometry.

Billing AM, Ben Hamidane H, Graumann J.

Curr Protoc Mouse Biol. 2015 Mar 2;5(1):1-20. doi: 10.1002/9780470942390.mo140156.

PMID:
25727197
33.

microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.

Marcais A, Blevins R, Graumann J, Feytout A, Dharmalingam G, Carroll T, Amado IF, Bruno L, Lee K, Walzer T, Mann M, Freitas AA, Boothby M, Fisher AG, Merkenschlager M.

J Exp Med. 2014 Oct 20;211(11):2281-95. doi: 10.1084/jem.20132059. Epub 2014 Oct 13.

34.

Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver.

Blanc V, Park E, Schaefer S, Miller M, Lin Y, Kennedy S, Billing AM, Ben Hamidane H, Graumann J, Mortazavi A, Nadeau JH, Davidson NO.

Genome Biol. 2014 Jun 19;15(6):R79. doi: 10.1186/gb-2014-15-6-r79.

35.

Adaptation of a commonly used, chemically defined medium for human embryonic stem cells to stable isotope labeling with amino acids in cell culture.

Liberski AR, Al-Noubi MN, Rahman ZH, Halabi NM, Dib SS, Al-Mismar R, Billing AM, Krishnankutty R, Ahmad FS, Raynaud CM, Rafii A, Engholm-Keller K, Graumann J.

J Proteome Res. 2013 Jul 5;12(7):3233-45. doi: 10.1021/pr400099j. Epub 2013 Jun 25.

36.

A SILAC-based approach identifies substrates of caspase-dependent cleavage upon TRAIL-induced apoptosis.

Stoehr G, Schaab C, Graumann J, Mann M.

Mol Cell Proteomics. 2013 May;12(5):1436-50. doi: 10.1074/mcp.M112.024679. Epub 2013 Jan 13.

37.

MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.

O'Loghlen A, Muñoz-Cabello AM, Gaspar-Maia A, Wu HA, Banito A, Kunowska N, Racek T, Pemberton HN, Beolchi P, Lavial F, Masui O, Vermeulen M, Carroll T, Graumann J, Heard E, Dillon N, Azuara V, Snijders AP, Peters G, Bernstein E, Gil J.

Cell Stem Cell. 2012 Jan 6;10(1):33-46. doi: 10.1016/j.stem.2011.12.004.

38.

A framework for intelligent data acquisition and real-time database searching for shotgun proteomics.

Graumann J, Scheltema RA, Zhang Y, Cox J, Mann M.

Mol Cell Proteomics. 2012 Mar;11(3):M111.013185. doi: 10.1074/mcp.M111.013185. Epub 2011 Dec 13.

39.

Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming.

Singhal N, Graumann J, Wu G, Araúzo-Bravo MJ, Han DW, Greber B, Gentile L, Mann M, Schöler HR.

Cell. 2010 Jun 11;141(6):943-55. doi: 10.1016/j.cell.2010.04.037.

40.

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ.

Cell. 2008 Sep 5;134(5):804-16. doi: 10.1016/j.cell.2008.06.048.

41.

Stable isotope labeling by amino acids in cell culture (SILAC) and proteome quantitation of mouse embryonic stem cells to a depth of 5,111 proteins.

Graumann J, Hubner NC, Kim JB, Ko K, Moser M, Kumar C, Cox J, Schöler H, Mann M.

Mol Cell Proteomics. 2008 Apr;7(4):672-83. Epub 2007 Nov 28.

42.

Quantitative profiling of ubiquitylated proteins reveals proteasome substrates and the substrate repertoire influenced by the Rpn10 receptor pathway.

Mayor T, Graumann J, Bryan J, MacCoss MJ, Deshaies RJ.

Mol Cell Proteomics. 2007 Nov;6(11):1885-95. Epub 2007 Jul 20.

43.

Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging.

Dieterich DC, Lee JJ, Link AJ, Graumann J, Tirrell DA, Schuman EM.

Nat Protoc. 2007;2(3):532-40.

PMID:
17406607
44.

Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT).

Dieterich DC, Link AJ, Graumann J, Tirrell DA, Schuman EM.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9482-7. Epub 2006 Jun 12.

45.

The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria.

Griffin EE, Graumann J, Chan DC.

J Cell Biol. 2005 Jul 18;170(2):237-48. Epub 2005 Jul 11.

46.

Analysis of polyubiquitin conjugates reveals that the Rpn10 substrate receptor contributes to the turnover of multiple proteasome targets.

Mayor T, Lipford JR, Graumann J, Smith GT, Deshaies RJ.

Mol Cell Proteomics. 2005 Jun;4(6):741-51. Epub 2005 Feb 7.

47.

MS1, MS2, and SQT-three unified, compact, and easily parsed file formats for the storage of shotgun proteomic spectra and identifications.

McDonald WH, Tabb DL, Sadygov RG, MacCoss MJ, Venable J, Graumann J, Johnson JR, Cociorva D, Yates JR 3rd.

Rapid Commun Mass Spectrom. 2004;18(18):2162-8.

PMID:
15317041
48.
49.

Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast.

Graumann J, Dunipace LA, Seol JH, McDonald WH, Yates JR 3rd, Wold BJ, Deshaies RJ.

Mol Cell Proteomics. 2004 Mar;3(3):226-37. Epub 2003 Dec 5.

50.

Activation of the redox-regulated molecular chaperone Hsp33--a two-step mechanism.

Graumann J, Lilie H, Tang X, Tucker KA, Hoffmann JH, Vijayalakshmi J, Saper M, Bardwell JC, Jakob U.

Structure. 2001 May 9;9(5):377-87.

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