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Items: 11


MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.

Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP.

J Immunol. 2004 Jan 15;172(2):871-9.


Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress.

Mathews CE, Graser RT, Bagley RJ, Caldwell JW, Li R, Churchill GA, Serreze DV, Leiter EH.

Immunogenetics. 2003 Oct;55(7):491-6. Epub 2003 Sep 25.


Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.

Marron MP, Graser RT, Chapman HD, Serreze DV.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13753-8. Epub 2002 Oct 2.


Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.

Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.

Diabetes. 2001 Sep;50(9):1992-2000.


Unusual resistance of ALR/Lt mouse beta cells to autoimmune destruction: role for beta cell-expressed resistance determinants.

Mathews CE, Graser RT, Savinov A, Serreze DV, Leiter EH.

Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):235-40.


Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.

Graser RT, DiLorenzo TP, Wang F, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV.

J Immunol. 2000 Apr 1;164(7):3913-8.


Reevaluation of the major histocompatibility complex genes of the NOD-progenitor CTS/Shi strain.

Mathews CE, Graser RT, Serreze DV, Leiter EH.

Diabetes. 2000 Jan;49(1):131-4.


MHC characterization of ALR and ALS mice: respective similarities to the NOD and NON strains.

Graser RT, Mathews CE, Leiter EH, Serreze DV.

Immunogenetics. 1999 Jul;49(7-8):722-6. No abstract available.


Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement.

DiLorenzo TP, Graser RT, Ono T, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12538-43.


Cloning and characterization of a 70 kd heat shock cognate (hsc70) gene from the zebrafish (Danio rerio).

Graser RT, Malnar-Dragojevic D, Vincek V.

Genetica. 1996-1997;98(3):273-6.


Molecular cloning of major histocompatibility complex class II B gene cDNA from the Bengalese finch Lonchura striata.

Vincek V, Klein D, Graser RT, Figueroa F, O'hUigin C, Klein J.

Immunogenetics. 1995;42(4):262-7.


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