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Items: 1 to 50 of 131

1.

Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.

Charton J, Gauriot M, Totobenazara J, Hennuyer N, Dumont J, Bosc D, Marechal X, Elbakali J, Herledan A, Wen X, Ronco C, Gras-Masse H, Heninot A, Pottiez V, Landry V, Staels B, Liang WG, Leroux F, Tang WJ, Deprez B, Deprez-Poulain R.

Eur J Med Chem. 2015 Jan 27;90:547-67. doi: 10.1016/j.ejmech.2014.12.005. Epub 2014 Dec 4.

2.

Inhibition of aggrecanases as a therapeutic strategy in osteoarthritis.

El Bakali J, Gras-Masse H, Maingot L, Deprez B, Dumont J, Leroux F, Deprez-Poulain R.

Future Med Chem. 2014;6(12):1399-412. doi: 10.4155/fmc.14.84. Review.

PMID:
25329196
3.

Parallel synthesis of a lipopeptide library by hydrazone-based chemical ligation.

Dubs P, Bourel-Bonnet L, Subra G, Blanpain A, Melnyk O, Pinel AM, Gras-Masse H, Martinez J.

J Comb Chem. 2007 Nov-Dec;9(6):973-81. Epub 2007 Sep 27.

PMID:
17896820
4.

[Neuraminidase inhibitors and risk of H5N1 influenza].

Gras-Masse H, Willand N.

Ann Pharm Fr. 2007 Jan;65(1):50-7. Review. French.

PMID:
17299351
5.

SIV escape mutants in rhesus macaques vaccinated with NEF-derived lipopeptides and challenged with pathogenic SIVmac251.

Villefroy P, Letourneur F, Coutsinos Z, Mortara L, Beyer C, Gras-Masse H, Guillet JG, Bourgault-Villada I.

Virol J. 2006 Aug 31;3:65.

6.

Effect of glycoamphiphiles on the solubilization and dendritic cell uptake of a lipopeptide: a preliminary study.

Bonnet D, Angyalosi G, Demory A, Santraine V, Boulet A, Spriet C, Héliot L, Gras-Masse H, Grandjean C.

Mol Pharm. 2005 Sep-Oct;2(5):420-7.

PMID:
16196495
7.

Anchorage of synthetic peptides onto liposomes via hydrazone and alpha-oxo hydrazone bonds. preliminary functional investigations.

Bourel-Bonnet L, Pécheur EI, Grandjean C, Blanpain A, Baust T, Melnyk O, Hoflack B, Gras-Masse H.

Bioconjug Chem. 2005 Mar-Apr;16(2):450-7.

PMID:
15769100
8.

Evaluation of SIV-lipopeptide immunizations administered by the intradermal route in their ability to induce antigen specific T-cell responses in rhesus macaques.

Coutsinos Z, Villefroy P, Gras-Masse H, Guillet JG, Bourgault-Villada I.

FEMS Immunol Med Microbiol. 2005 Mar 1;43(3):357-66.

10.

Peptide-protein microarrays for the simultaneous detection of pathogen infections.

Duburcq X, Olivier C, Malingue F, Desmet R, Bouzidi A, Zhou F, Auriault C, Gras-Masse H, Melnyk O.

Bioconjug Chem. 2004 Mar-Apr;15(2):307-16.

PMID:
15025526
11.

Lipid vector for the delivery of peptides towards intracellular pharmacological targets.

Gras-Masse H.

J Mol Recognit. 2003 Sep-Oct;16(5):234-9. Review.

PMID:
14523934
12.

Long-term specific immune responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine: characterization of CD8+-T-cell epitopes recognized.

Gahéry-Ségard H, Pialoux G, Figueiredo S, Igéa C, Surenaud M, Gaston J, Gras-Masse H, Lévy JP, Guillet JG.

J Virol. 2003 Oct;77(20):11220-31.

13.

Solid-phase functionalization of peptides by an alpha-hydrazinoacetyl group.

Bonnet D, Grandjean C, Rousselot-Pailley P, Joly P, Bourel-Bonnet L, Santraine V, Gras-Masse H, Melnyk O.

J Org Chem. 2003 Sep 5;68(18):7033-40.

PMID:
12946145
14.

Identification of novel immunodominant CD4+ Th1-type T-cell peptide epitopes from herpes simplex virus glycoprotein D that confer protective immunity.

BenMohamed L, Bertrand G, McNamara CD, Gras-Masse H, Hammer J, Wechsler SL, Nesburn AB.

J Virol. 2003 Sep;77(17):9463-73.

15.

Simultaneous lipidation of a characterized peptide mixture by chemoselective ligation.

Bourel-Bonnet L, Bonnet D, Malingue F, Gras-Masse H, Melnyk O.

Bioconjug Chem. 2003 Mar-Apr;14(2):494-9.

PMID:
12643762
16.

Alpha-oxo semicarbazone peptide or oligodeoxynucleotide microarrays.

Olivier C, Hot D, Huot L, Ollivier N, El-Mahdi O, Gouyette C, Huynh-Dinh T, Gras-Masse H, Lemoine Y, Melnyk O.

Bioconjug Chem. 2003 Mar-Apr;14(2):430-9.

PMID:
12643754
17.

Grafting of synthetic mannose receptor-ligands onto onion vectors for human dendritic cells targeting.

Chenevier P, Grandjean C, Loing E, Malingue F, Angyalosi G, Gras-Masse H, Roux D, Melnyk O, Bourel-Bonnet L.

Chem Commun (Camb). 2002 Oct 21;(20):2446-7.

PMID:
12430483
18.

Synthesis and mannose receptor-mediated uptake of clustered glycomimetics by human dendritic cells: effect of charge.

Angyalosi G, Grandjean C, Lamirand M, Auriault C, Gras-Masse H, Melnyk O.

Bioorg Med Chem Lett. 2002 Oct 7;12(19):2723-7.

PMID:
12217363
19.

Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant.

BenMohamed L, Belkaid Y, Loing E, Brahimi K, Gras-Masse H, Druilhe P.

Eur J Immunol. 2002 Aug;32(8):2274-81.

20.

Human leukocyte antigen class II control of the immune response to p126-derived amino terminal peptide from Plasmodium falciparum.

Banic DM, Goldberg AC, Pratt-Riccio LR, De Oliveira-Ferreira J, Santos F, Gras-Masse H, Camus D, Kalil J, Daniel-Ribeiro CT.

Am J Trop Med Hyg. 2002 May;66(5):509-15.

PMID:
12201584
21.

Combined thioether/hydrazone chemoselective ligation reactions for the synthesis of glycocluster-antigen peptide conjugates.

Grandjean C, Santraine V, Fruchart JS, Melnyk O, Gras-Masse H.

Bioconjug Chem. 2002 Jul-Aug;13(4):887-92.

PMID:
12121146
22.

Peptide arrays for highly sensitive and specific antibody-binding fluorescence assays.

Melnyk O, Duburcq X, Olivier C, Urbès F, Auriault C, Gras-Masse H.

Bioconjug Chem. 2002 Jul-Aug;13(4):713-20.

PMID:
12121125
23.

Novel hyperbranched glycomimetics recognized by the human mannose receptor: quinic or shikimic acid derivatives as mannose bioisosteres.

Grandjean C, Angyalosi G, Loing E, Adriaenssens E, Melnyk O, Pancré V, Auriault C, Gras-Masse H.

Chembiochem. 2001 Oct 1;2(10):747-57.

PMID:
11948857
24.

Lipopeptide-based melanoma cancer vaccine induced a strong MART-27-35-cytotoxic T lymphocyte response in a preclinal study.

Le Gal FA, Prevost-Blondel A, Lengagne R, Bossus M, Farace F, Chaboissier A, Gras-Masse H, Engelhard VH, Guillet JG, Gahéry-Ségard H.

Int J Cancer. 2002 Mar 10;98(2):221-7.

25.

Chemoselective ligation and antigen vectorization.

Gras-Masse H.

Biologicals. 2001 Sep-Dec;29(3-4):183-8.

PMID:
11851314
26.

Solid-phase enolate chemistry investigated using HR-MAS NMR spectroscopy.

Fruchart JS, Lippens G, Kuhn C, Gras-Masse H, Melnyk O.

J Org Chem. 2002 Jan 25;67(2):526-32.

PMID:
11798327
28.

Lipopeptide presentation pathway in dendritic cells.

Hosmalin A, Andrieu M, Loing E, Desoutter JF, Hanau D, Gras-Masse H, Dautry-Varsat A, Guillet JG.

Immunol Lett. 2001 Nov 1;79(1-2):97-100.

PMID:
11595295
29.

Modulation of the allergen-induced human IgE response in Hu-SCID mice: inhibitory effect of human recombinant IFN-gamma and allergen-derived lipopeptide.

Duez C, Gras-Masse H, Hammad H, Akoum H, Didierlaurent A, André C, Tonnel AB, Pestel J.

Eur Cytokine Netw. 2001 Jul-Sep;12(3):453-61.

30.

Synthesis by chemoselective ligation and biological evaluation of novel cell-permeable PKC-zeta pseudosubstrate lipopeptides.

Bonnet D, Thiam K, Loing E, Melnyk O, Gras-Masse H.

J Med Chem. 2001 Feb 1;44(3):468-71.

PMID:
11462985
31.

Chemoselective acylation of fully deprotected hydrazino acetyl peptides. Application to the synthesis of lipopetides.

Bonnet D, Ollivier N, Gras-Masse H, Melnyk O.

J Org Chem. 2001 Jan 26;66(2):443-9.

PMID:
11429812
32.

Lipopeptides induce cell-mediated anti-HIV immune responses in seronegative volunteers.

Pialoux G, Gahéry-Ségard H, Sermet S, Poncelet H, Fournier S, Gérard L, Tartar A, Gras-Masse H, Levy JP, Guillet JG; ANRS VAC 04 Study Team.

AIDS. 2001 Jul 6;15(10):1239-49.

PMID:
11426068
33.

Tartric acid-based linker for the solid-phase synthesis of C-terminal peptide alpha-oxo aldehydes.

Melnyk O, Fruchart JS, Grandjean C, Gras-Masse H.

J Org Chem. 2001 Jun 15;66(12):4153-60.

PMID:
11397147
34.
35.

Temporal loss of Nef-epitope CTL recognition following macaque lipopeptide immunization and SIV challenge.

Mortara L, Letourneur F, Villefroy P, Beyer C, Gras-Masse H, Guillet JG, Bourgault-Villada I.

Virology. 2000 Dec 20;278(2):551-61.

36.

Endocytosis of an HIV-derived lipopeptide into human dendritic cells followed by class I-restricted CD8(+) T lymphocyte activation.

Andrieu M, Loing E, Desoutter JF, Connan F, Choppin J, Gras-Masse H, Hanau D, Dautry-Varsat A, Guillet JG, Hosmalin A.

Eur J Immunol. 2000 Nov;30(11):3256-65.

37.

Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3.

Daubersies P, Thomas AW, Millet P, Brahimi K, Langermans JA, Ollomo B, BenMohamed L, Slierendregt B, Eling W, Van Belkum A, Dubreuil G, Meis JF, Guérin-Marchand C, Cayphas S, Cohen J, Gras-Masse H, Druilhe P.

Nat Med. 2000 Nov;6(11):1258-63. Erratum in: Nat Med 2000 Dec;6(12):1412. Mohamed LB [corrected to BenMohamed L].

PMID:
11062538
38.

Functionalization of peptides and proteins by aldehyde or keto groups.

Melnyk O, Fehrentz JA, Martinez J, Gras-Masse H.

Biopolymers. 2000;55(2):165-86. Review.

PMID:
11074412
39.

Structural diversity of human class II histocompatibility molecules induced by peptide ligands.

Georges B, Loing E, Neveu R, Melnyk O, Gras-Masse H, Auriault C.

FEBS Lett. 2000 Sep 22;481(3):249-54.

40.

The deprotection of Lys(Mtt) revisited.

Bourel L, Carion O, Gras-Masse H, Melnyk O.

J Pept Sci. 2000 Jun;6(6):264-70.

PMID:
10912906
41.

High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules.

Benmohamed L, Thomas A, Bossus M, Brahimi K, Wubben J, Gras-Masse H, Druilhe P.

Vaccine. 2000 Jun 15;18(25):2843-55.

PMID:
10812228
43.

Multiepitopic B- and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine.

Gahéry-Ségard H, Pialoux G, Charmeteau B, Sermet S, Poncelet H, Raux M, Tartar A, Lévy JP, Gras-Masse H, Guillet JG.

J Virol. 2000 Feb;74(4):1694-703.

44.

Extension of HLA-A*0201-restricted minimal epitope by N epsilon-palmitoyl-lysine increases the life span of functional presentation to cytotoxic T cells.

Loing E, Andrieu M, Thiam K, Schörner D, Wiesmüller KH, Hosmalin A, Jung G, Gras-Masse H.

J Immunol. 2000 Jan 15;164(2):900-7.

45.
46.

Direct evidence of cytoplasmic delivery of PKC-alpha, -epsilon and -zeta pseudosubstrate lipopeptides: study of their implication in the induction of apoptosis.

Thiam K, Loing E, Zoukhri D, Rommens C, Hodges R, Dartt D, Verwaerde C, Auriault C, Gras-Masse H, Sergheraert C.

FEBS Lett. 1999 Oct 15;459(3):285-90.

47.

Reactivity of Lys(NH2)-containing peptides toward endopeptidases.

Samson F, Bonnet D, Rommens C, Gras-Masse H, Melnyk O.

J Pept Sci. 1999 Aug;5(8):352-9.

PMID:
10507684
48.

Characterization of a multi-lipopeptides mixture used as an HIV-1 vaccine candidate.

Klinguer C, David D, Kouach M, Wieruszeski JM, Tartar A, Marzin D, Levy JP, Gras-Masse H.

Vaccine. 1999 Sep;18(3-4):259-67.

PMID:
10506650
49.

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