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Preoperative ECMO and plasmapheresis for urgent pulmonary endarterectomy in HIT positive patient.

Tahiri M, Bykova A, Dunne B, Barth D, Donahoe L, Waddell TK, McRae K, Slinger P, Granton J, de Perrot M.

Ann Thorac Surg. 2019 Oct 4. pii: S0003-4975(19)31484-5. doi: 10.1016/j.athoracsur.2019.08.092. [Epub ahead of print]


Heart rate variability in pulmonary hypertension with and without sleep apnea.

Carvalho CG, Bresler R, Zhi YX, Alshaer H, Granton JT, Ryan CM.

Heliyon. 2019 Jul 3;5(7):e02034. doi: 10.1016/j.heliyon.2019.e02034. eCollection 2019 Jul.


Medical oncologists' and palliative care physicians' opinions towards thromboprophylaxis for inpatients with advanced cancer: a cross-sectional study.

Hannon B, Taback N, Zimmermann C, Granton J, Krzyzanowska M.

BMJ Support Palliat Care. 2019 Jul 11. pii: bmjspcare-2019-001861. doi: 10.1136/bmjspcare-2019-001861. [Epub ahead of print]


Dyspnea after Pulmonary Embolism.

Christiansen D, Baillie T, Mak S, Granton J.

Ann Am Thorac Soc. 2019 Jul;16(7):914-919. doi: 10.1513/AnnalsATS.201811-818CC. No abstract available.


Temporal shifts in fluid in pulmonary hypertension with and without sleep apnea.

Carvalho CG, Yadollahi A, Granton J, Ryan CM.

J Sleep Res. 2019 May 16:e12863. doi: 10.1111/jsr.12863. [Epub ahead of print]


Pulmonary hypertension in patients with a subaortic right ventricle: prevalence, impact and management.

Van De Bruaene A, Toh N, Hickey EJ, Benson L, Horlick E, Granton JT, Williams WG, Roche SL.

Heart. 2019 Oct;105(19):1471-1478. doi: 10.1136/heartjnl-2019-314756. Epub 2019 May 3.


Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension.

Mura M, Cecchini MJ, Joseph M, Granton JT.

Respirology. 2019 Nov;24(11):1104-1110. doi: 10.1111/resp.13557. Epub 2019 Apr 8.


Thromboprophylaxis for inpatients with advanced cancer in palliative care settings: A systematic review and narrative synthesis.

Cai R, Zimmermann C, Krzyzanowska M, Granton J, Hannon B.

Palliat Med. 2019 May;33(5):486-499. doi: 10.1177/0269216319830860. Epub 2019 Mar 1.


Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients.

Schlosser K, Wang JP, Dos Santos C, Walley KR, Marshall J, Fergusson DA, Winston BW, Granton J, Watpool I, Stewart DJ, McIntyre LA, Mei SHJ; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.

Crit Care Med. 2019 Jul;47(7):918-925. doi: 10.1097/CCM.0000000000003657.


Myeloid angiogenic cells exhibit impaired migration, reduced expression of endothelial markers, and increased apoptosis in idiopathic pulmonary arterial hypertension 1.

Zhang Q, Zucco L, Toshner M, Morrell NW, Granton J, Stewart DJ, Kutryk MJB.

Can J Physiol Pharmacol. 2019 Apr;97(4):306-312. doi: 10.1139/cjpp-2018-0424. Epub 2018 Dec 17.


Clinical trial design and new therapies for pulmonary arterial hypertension.

Sitbon O, Gomberg-Maitland M, Granton J, Lewis MI, Mathai SC, Rainisio M, Stockbridge NL, Wilkins MR, Zamanian RT, Rubin LJ.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801908. doi: 10.1183/13993003.01908-2018. Print 2019 Jan.


Serial imaging after pulmonary embolism and correlation with functional limitation at 12 months: Results of the ELOPE Study.

Ma KA, Kahn SR, Akaberi A, Dennie C, Rush C, Granton JT, Anderson D, Wells PS, Rodger MA, Solymoss S, Kovacs MJ, Rudski L, Shimony A, Hernandez P, Aaron SD, Pena E, Abikhzer G, Hirsch AM; ELOPE Study group.

Res Pract Thromb Haemost. 2018 Jun 17;2(4):670-677. doi: 10.1002/rth2.12123. eCollection 2018 Oct.


Determining the minimal clinically important difference for the PEmbQoL questionnaire, a measure of pulmonary embolism-specific quality of life.

Akaberi A, Klok FA, Cohn DM, Hirsch A, Granton J, Kahn SR.

J Thromb Haemost. 2018 Dec;16(12):2454-2461. doi: 10.1111/jth.14302. Epub 2018 Nov 2.


Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study.

Wijeysundera DN, Pearse RM, Shulman MA, Abbott TEF, Torres E, Ambosta A, Croal BL, Granton JT, Thorpe KE, Grocott MPW, Farrington C, Myles PS, Cuthbertson BH; METS study investigators.

Lancet. 2018 Jun 30;391(10140):2631-2640. doi: 10.1016/S0140-6736(18)31131-0.


Exertional Oxygen Requirements During Exercise Training in Advanced Interstitial Lung Disease.

Wickerson L, Brooks D, Reid WD, Singer LG, Granton J, Mathur S.

J Cardiopulm Rehabil Prev. 2018 Nov;38(6):419-424. doi: 10.1097/HCR.0000000000000338.


Renal thrombotic microangiopathy and pulmonary arterial hypertension in a patient with late-onset cobalamin C deficiency.

Petropoulos TE, Ramirez ME, Granton J, Licht C, John R, Moayedi Y, Morel CF, McQuillan RF.

Clin Kidney J. 2018 Jun;11(3):310-314. doi: 10.1093/ckj/sfx119. Epub 2017 Oct 26.


Flow-related right ventricular to pulmonary arterial pressure gradients during exercise.

Wright SP, Opotowsky AR, Buchan TA, Esfandiari S, Granton JT, Goodman JM, Mak S.

Cardiovasc Res. 2019 Jan 1;115(1):222-229. doi: 10.1093/cvr/cvy138.


Applied Bayesian Methods in the Rheumatic Diseases.

Johnson SR, Tomlinson GA, Granton JT, Hawker GA, Feldman BM.

Rheum Dis Clin North Am. 2018 May;44(2):361-370. doi: 10.1016/j.rdc.2018.01.003. Review.


Propensity Score Methods for Bias Reduction in Observational Studies of Treatment Effect.

Johnson SR, Tomlinson GA, Hawker GA, Granton JT, Feldman BM.

Rheum Dis Clin North Am. 2018 May;44(2):203-213. doi: 10.1016/j.rdc.2018.01.002. Review.


Heparin-Induced Thrombocytopenia in the Critically Ill Patient.

East JM, Cserti-Gazdewich CM, Granton JT.

Chest. 2018 Sep;154(3):678-690. doi: 10.1016/j.chest.2017.11.039. Epub 2017 Dec 16. Review.


The feasibility of assessing swallowing physiology following prolonged intubation after cardiovascular surgery.

Skoretz SA, Yau TM, Granton JT, Martino R.

Pilot Feasibility Stud. 2017 Nov 21;3:62. doi: 10.1186/s40814-017-0199-7. eCollection 2017.


Lung Transplantation for Pulmonary Hypertension and Strategies to Bridge to Transplant.

Baillie TJ, Granton JT.

Semin Respir Crit Care Med. 2017 Oct;38(5):701-710. doi: 10.1055/s-0037-1606223. Epub 2017 Oct 15. Review. No abstract available.


Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension: New Horizons in the Interventional Management of Pulmonary Embolism.

Rivers-Bowerman MD, Zener R, Jaberi A, de Perrot M, Granton J, Moriarty JM, Tan KT.

Tech Vasc Interv Radiol. 2017 Sep;20(3):206-215. doi: 10.1053/j.tvir.2017.07.011. Epub 2017 Jul 5. Review.


Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial.

McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Winston BW, Schlosser K, Fergusson DA; Canadian Critical Care Trials Group; Canadian Critical Care Translational Biology Group.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):337-347. doi: 10.1164/rccm.201705-1006OC.


Metabolic heterogeneity of idiopathic pulmonary fibrosis: a metabolomic study.

Zhao YD, Yin L, Archer S, Lu C, Zhao G, Yao Y, Wu L, Hsin M, Waddell TK, Keshavjee S, Granton J, de Perrot M.

BMJ Open Respir Res. 2017 Jun 5;4(1):e000183. doi: 10.1136/bmjresp-2017-000183. eCollection 2017.


Symptoms Are More Useful Than Echocardiography in Patient Selection for Pulmonary Endarterectomy.

Donahoe L, Vanderlaan R, Thenganatt J, McRae K, Bykova A, Moric J, Granton J, de Perrot M.

Ann Thorac Surg. 2017 Oct;104(4):1179-1185. doi: 10.1016/j.athoracsur.2017.05.024. Epub 2017 Aug 16.


Impact of Left Ventricular Diastolic Dysfunction on Lung Transplantation Outcome in Patients With Pulmonary Arterial Hypertension.

Avriel A, Klement AH, Johnson SR, de Perrot M, Granton J.

Am J Transplant. 2017 Oct;17(10):2705-2711. doi: 10.1111/ajt.14352. Epub 2017 Jul 3.


Erratum to: Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine.

Mehta S, Granton J, Gordon AC, Cook DJ, Lapinsky S, Newton G, Bandayrel K, Little A, Siau C, Ayers D, Singer J, Lee TCK, Walley KR, Storms M, Cooper DJ, Holmes CL, Hebert P, Presneill J, Russell JA; Vasopressin and Septic Shock Trial (VASST) Investigators.

Crit Care. 2017 May 4;21(1):98. doi: 10.1186/s13054-017-1680-7. No abstract available.


Quality of Life, Dyspnea, and Functional Exercise Capacity Following a First Episode of Pulmonary Embolism: Results of the ELOPE Cohort Study.

Kahn SR, Akaberi A, Granton JT, Anderson DR, Wells PS, Rodger MA, Solymoss S, Kovacs MJ, Rudski L, Shimony A, Dennie C, Rush C, Hernandez P, Aaron SD, Hirsch AM.

Am J Med. 2017 Aug;130(8):990.e9-990.e21. doi: 10.1016/j.amjmed.2017.03.033. Epub 2017 Apr 8.


N-terminal of prohormone brain natriuretic peptide predicts functional limitation one year following pulmonary embolism: Results from the ELOPE study.

Ma K, Kahn SR, Hirsch AM, Akaberi A, Anderson DR, Wells PS, Rodger M, Solymoss S, Kovacs MJ, Rudski L, Shimony A, Dennie C, Rush C, Hernandez P, Aaron SD, Granton JT.

Thromb Res. 2017 May;153:47-49. doi: 10.1016/j.thromres.2017.03.005. Epub 2017 Mar 8. No abstract available.


Exhaled Nitric Oxide in Systemic Sclerosis Lung Disease.

Kozij NK, Granton JT, Silkoff PE, Thenganatt J, Chakravorty S, Johnson SR.

Can Respir J. 2017;2017:6736239. doi: 10.1155/2017/6736239. Epub 2017 Feb 14.


A case of pulmonary arterial hypertension associated with adult hemophagocytic lymphohistiocytosis.

Koifman J, Granton J, Thenganatt J.

Pulm Circ. 2016 Dec;6(4):614-615. doi: 10.1086/688490.


Functional and Exercise Limitations After a First Episode of Pulmonary Embolism: Results of the ELOPE Prospective Cohort Study.

Kahn SR, Hirsch AM, Akaberi A, Hernandez P, Anderson DR, Wells PS, Rodger MA, Solymoss S, Kovacs MJ, Rudski L, Shimony A, Dennie C, Rush C, Geerts WH, Aaron SD, Granton JT.

Chest. 2017 May;151(5):1058-1068. doi: 10.1016/j.chest.2016.11.030. Epub 2016 Dec 6.


Erratum to: Risk factors for mortality in patients admitted to intensive care units with pneumonia.

Li G, Cook DJ, Thabane L, Friedrich JO, Crozier TM, Muscedere J, Granton J, Mehta S, Reynolds SC, Lopes RD, Lauzier F, Freitag AP, Levine MA; PROTECT Investigators for the Canadian Critical Care Trials Group; Australian and New Zealand Intensive Care Society Clinical Trials Group.

Respir Res. 2016 Oct 7;17(1):128. No abstract available.


The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario.

Vaid HM, Camacho X, Granton JT, Mamdani MM, Yao Z, Singh S, Juurlink DN, Gomes T.

Can Respir J. 2016;2016:6279250. doi: 10.1155/2016/6279250. Epub 2016 Apr 11.


Risk factors for mortality in patients admitted to intensive care units with pneumonia.

Li G, Cook DJ, Thabane L, Friedrich JO, Crozier TM, Muscedere J, Granton J, Mehta S, Reynolds SC, Lopes RD, Lauzier F, Freitag AP, Levine MA; PROTECT Investigators for the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group.

Respir Res. 2016 Jul 11;17(1):80. doi: 10.1186/s12931-016-0397-5. Erratum in: Respir Res. 2016 Oct 7;17 (1):128.


Online obituaries are a reliable and valid source of mortality data.

Soowamber ML, Granton JT, Bavaghar-Zaeimi F, Johnson SR.

J Clin Epidemiol. 2016 Nov;79:167-168. doi: 10.1016/j.jclinepi.2016.05.012. Epub 2016 Jun 29. No abstract available.


Role of extracorporeal life support after pulmonary endarterectomy: a single-centre experience.

Donahoe L, Granton J, McRae K, Thenganatt J, Moric J, Keshavjee S, de Perrot M.

Interact Cardiovasc Thorac Surg. 2016 Jul;23(1):74-8. doi: 10.1093/icvts/ivw075. Epub 2016 Mar 30.


Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery.

Wijeysundera DN, Pearse RM, Shulman MA, Abbott TE, Torres E, Croal BL, Granton JT, Thorpe KE, Grocott MP, Farrington C, Myles PS, Cuthbertson BH; METS Study Investigators.

BMJ Open. 2016 Mar 11;6(3):e010359. doi: 10.1136/bmjopen-2015-010359. Erratum in: BMJ Open. 2016;6(4):e010359corr1.


The relationship of pulmonary vascular resistance and compliance to pulmonary artery wedge pressure during submaximal exercise in healthy older adults.

Wright SP, Granton JT, Esfandiari S, Goodman JM, Mak S.

J Physiol. 2016 Jun 15;594(12):3307-15. doi: 10.1113/JP271788. Epub 2016 Mar 24.


Sex disparities in systemic sclerosis-associated pulmonary arterial hypertension: a cohort study.

Pasarikovski CR, Granton JT, Roos AM, Sadeghi S, Kron AT, Thenganatt J, Moric J, Chau C, Johnson SR.

Arthritis Res Ther. 2016 Jan 27;18:30. doi: 10.1186/s13075-016-0933-1.


The pulmonary artery wedge pressure response to sustained exercise is time-variant in healthy adults.

Wright SP, Esfandiari S, Gray T, Fuchs FC, Chelvanathan A, Chan W, Sasson Z, Granton JT, Goodman JM, Mak S.

Heart. 2016 Mar;102(6):438-43. doi: 10.1136/heartjnl-2015-308592. Epub 2016 Jan 13.


Riociguat for the treatment of pulmonary hypertension.

Hambly N, Granton J.

Expert Rev Respir Med. 2015;9(6):679-95. doi: 10.1586/17476348.2015.1106316. Epub 2015 Nov 24. Review.


Prevalence, risk factors, and outcomes associated with physical restraint use in mechanically ventilated adults.

Rose L, Burry L, Mallick R, Luk E, Cook D, Fergusson D, Dodek P, Burns K, Granton J, Ferguson N, Devlin JW, Steinberg M, Keenan S, Reynolds S, Tanios M, Fowler RA, Jacka M, Olafson K, Skrobik Y, Mehta S.

J Crit Care. 2016 Feb;31(1):31-5. doi: 10.1016/j.jcrc.2015.09.011. Epub 2015 Sep 25.


A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung.

Zhao YD, Chu L, Lin K, Granton E, Yin L, Peng J, Hsin M, Wu L, Yu A, Waddell T, Keshavjee S, Granton J, de Perrot M.

PLoS One. 2015 Aug 28;10(8):e0134958. doi: 10.1371/journal.pone.0134958. eCollection 2015.


Endothelial NO-Synthase Gene-Enhanced Progenitor Cell Therapy for Pulmonary Arterial Hypertension: The PHACeT Trial.

Granton J, Langleben D, Kutryk MB, Camack N, Galipeau J, Courtman DW, Stewart DJ.

Circ Res. 2015 Sep 11;117(7):645-54. doi: 10.1161/CIRCRESAHA.114.305951. Epub 2015 Jul 20.


Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption.

Burry L, Cook D, Herridge M, Devlin JW, Fergusson D, Meade M, Steinberg M, Skrobik Y, Olafson K, Burns K, Dodek P, Granton J, Ferguson N, Jacka M, Tanios M, Fowler R, Reynolds S, Keenan S, Mallick R, Mehta S; SLEAP Investigators; Canadian Critical Care Trials Group.

Crit Care Med. 2015 Oct;43(10):2180-90. doi: 10.1097/CCM.0000000000001196.


Effects of Recipient Age and Diagnosis on Health-related Quality-of-Life Benefit of Lung Transplantation.

Singer LG, Chowdhury NA, Faughnan ME, Granton J, Keshavjee S, Marras TK, Tullis DE, Waddell TK, Tomlinson G.

Am J Respir Crit Care Med. 2015 Oct 15;192(8):965-73. doi: 10.1164/rccm.201501-0126OC.


Focused transesophageal echocardiography for emergency physicians-description and results from simulation training of a structured four-view examination.

Arntfield R, Pace J, McLeod S, Granton J, Hegazy A, Lingard L.

Crit Ultrasound J. 2015 Dec;7(1):27. doi: 10.1186/s13089-015-0027-3. Epub 2015 Jun 12.


Critical care capacity in Canada: results of a national cross-sectional study.

Fowler RA, Abdelmalik P, Wood G, Foster D, Gibney N, Bandrauk N, Turgeon AF, Lamontagne F, Kumar A, Zarychanski R, Green R, Bagshaw SM, Stelfox HT, Foster R, Dodek P, Shaw S, Granton J, Lawless B, Hill A, Rose L, Adhikari NK, Scales DC, Cook DJ, Marshall JC, Martin C, Jouvet P; Canadian Critical Care Trials Group; Canadian ICU Capacity Group.

Crit Care. 2015 Apr 1;19:133. doi: 10.1186/s13054-015-0852-6.

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