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Items: 1 to 50 of 104

1.

Pulmonary embolism location is associated with the co-existence of the deep venous thrombosis.

Sane MA, Laukkanen JA, Granér MA, Piirilä PL, Harjola VP, Mustonen PE.

Blood Coagul Fibrinolysis. 2019 Jul;30(5):188-192. doi: 10.1097/MBC.0000000000000813.

PMID:
31157680
2.

Roles of Extracellular Vesicles in High-Grade Gliomas: Tiny Particles with Outsized Influence.

Graner MW.

Annu Rev Genomics Hum Genet. 2019 Aug 31;20:331-357. doi: 10.1146/annurev-genom-083118-015324. Epub 2019 Apr 12.

3.

V-ATPase expression in gliomas-Not your grandparents' proton pump.

Graner M.

EBioMedicine. 2019 Mar;41:13-14. doi: 10.1016/j.ebiom.2019.02.044. Epub 2019 Feb 23. No abstract available.

4.

The Potential of Exosomes From Cow Milk for Oral Delivery.

Betker JL, Angle BM, Graner MW, Anchordoquy TJ.

J Pharm Sci. 2019 Apr;108(4):1496-1505. doi: 10.1016/j.xphs.2018.11.022. Epub 2018 Nov 20.

PMID:
30468828
5.

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.

Lovric A, Granér M, Bjornson E, Arif M, Benfeitas R, Nyman K, Ståhlman M, Pentikäinen MO, Lundbom J, Hakkarainen A, Sirén R, Nieminen MS, Lundbom N, Lauerma K, Taskinen MR, Mardinoglu A, Boren J.

Sci Rep. 2018 Sep 21;8(1):14200. doi: 10.1038/s41598-018-31865-w.

6.

Extracellular vesicles in cancer immune responses: roles of purinergic receptors.

Graner MW.

Semin Immunopathol. 2018 Sep;40(5):465-475. doi: 10.1007/s00281-018-0706-9. Epub 2018 Sep 12. Review.

PMID:
30209547
7.

Combined volume of pulmonary embolism and deep venous thrombosis-Association with FV, platelet count, and D-dimer.

Sane M, Laukkanen JA, Granér M, Piilonen A, Raade M, Harjola VP, Mustonen P.

Int J Lab Hematol. 2018 Jun 9. doi: 10.1111/ijlh.12867. [Epub ahead of print] No abstract available.

PMID:
29885207
8.

Tumor-derived exosomes, microRNAs, and cancer immune suppression.

Graner MW, Schnell S, Olin MR.

Semin Immunopathol. 2018 Sep;40(5):505-515. doi: 10.1007/s00281-018-0689-6. Epub 2018 Jun 4. Review.

9.

Metabolic syndrome associates with left atrial dysfunction.

Nyman K, Granér M, Pentikäinen MO, Lundbom J, Hakkarainen A, Sirén R, Nieminen MS, Taskinen MR, Lundbom N, Lauerma K.

Nutr Metab Cardiovasc Dis. 2018 Jul;28(7):727-734. doi: 10.1016/j.numecd.2018.02.008. Epub 2018 Feb 21.

PMID:
29764718
10.

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

Mardinoglu A, Wu H, Bjornson E, Zhang C, Hakkarainen A, Räsänen SM, Lee S, Mancina RM, Bergentall M, Pietiläinen KH, Söderlund S, Matikainen N, Ståhlman M, Bergh PO, Adiels M, Piening BD, Granér M, Lundbom N, Williams KJ, Romeo S, Nielsen J, Snyder M, Uhlén M, Bergström G, Perkins R, Marschall HU, Bäckhed F, Taskinen MR, Borén J.

Cell Metab. 2018 Mar 6;27(3):559-571.e5. doi: 10.1016/j.cmet.2018.01.005. Epub 2018 Feb 15.

11.

Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases.

Contreras-Zárate MJ, Ormond DR, Gillen AE, Hanna C, Day NL, Serkova NJ, Jacobsen BM, Edgerton SM, Thor AD, Borges VF, Lillehei KO, Graner MW, Kabos P, Cittelly DM.

Front Oncol. 2017 Nov 2;7:252. doi: 10.3389/fonc.2017.00252. eCollection 2017.

12.

Glioblastoma multiforme-derived extracellular vesicles drive normal astrocytes towards a tumour-enhancing phenotype.

Oushy S, Hellwinkel JE, Wang M, Nguyen GJ, Gunaydin D, Harland TA, Anchordoquy TJ, Graner MW.

Philos Trans R Soc Lond B Biol Sci. 2018 Jan 5;373(1737). pii: 20160477. doi: 10.1098/rstb.2016.0477.

13.

The complex relationship between oligoclonal bands, lymphocytes in the cerebrospinal fluid, and immunoglobulin G antibodies in multiple sclerosis: Indication of serum contribution.

Beseler C, Vollmer T, Graner M, Yu X.

PLoS One. 2017 Oct 23;12(10):e0186842. doi: 10.1371/journal.pone.0186842. eCollection 2017.

14.

Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.

Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaah5360. doi: 10.1126/scitranslmed.aah5360.

15.

Plasma levels of haemostatic factors in patients with pulmonary embolism on admission and seven months later.

Sane M, Granér M, Laukkanen JA, Harjola VP, Mustonen P.

Int J Lab Hematol. 2018 Feb;40(1):66-71. doi: 10.1111/ijlh.12729. Epub 2017 Sep 4.

PMID:
28868636
16.

A method for extracting and characterizing RNA from urine: For downstream PCR and RNAseq analysis.

Zhou K, Spillman MA, Behbakht K, Komatsu JM, Abrahante JE, Hicks D, Schotl B, Odean E, Jones KL, Graner MW, Bemis LT.

Anal Biochem. 2017 Nov 1;536:8-15. doi: 10.1016/j.ab.2017.08.003. Epub 2017 Aug 10.

17.

HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line.

Graner AN, Hellwinkel JE, Lencioni AM, Madsen HJ, Harland TA, Marchando P, Nguyen GJ, Wang M, Russell LM, Bemis LT, Anchordoquy TJ, Graner MW.

Int J Hyperthermia. 2017 May;33(3):303-317. doi: 10.1080/02656736.2016.1256503. Epub 2016 Dec 20.

18.

Proteomic analyses of brain tumor cell lines amidst the unfolded protein response.

Redzic JS, Gomez JD, Hellwinkel JE, Anchordoquy TJ, Graner MW.

Oncotarget. 2016 Jul 26;7(30):47831-47847. doi: 10.18632/oncotarget.10032.

19.

HSP90 and Immune Modulation in Cancer.

Graner MW.

Adv Cancer Res. 2016;129:191-224. doi: 10.1016/bs.acr.2015.10.001. Epub 2015 Nov 3. Review.

PMID:
26916006
20.

N-terminal Pro-brain Natriuretic Peptide, High-sensitivity Troponin and Pulmonary Artery Clot Score as Predictors of Right Ventricular Dysfunction in Echocardiography.

Granér M, Harjola VP, Selander T, Laiho MK, Piilonen A, Raade M, Mustonen P.

Heart Lung Circ. 2016 Jun;25(6):592-9. doi: 10.1016/j.hlc.2015.12.004. Epub 2015 Dec 19.

PMID:
26809463
21.

Biomarkers and prediction of myocardial triglyceride content in non-diabetic men.

Granér M, Gustavsson S, Nyman K, Siren R, Pentikäinen MO, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Borén J, Nieminen MS, Taskinen MR.

Nutr Metab Cardiovasc Dis. 2016 Feb;26(2):134-40. doi: 10.1016/j.numecd.2015.11.002. Epub 2015 Dec 12.

PMID:
26803593
22.

The Dichotomy of Tumor Exosomes (TEX) in Cancer Immunity: Is It All in the ConTEXt?

Kunigelis KE, Graner MW.

Vaccines (Basel). 2015 Dec 17;3(4):1019-51. doi: 10.3390/vaccines3041019. Review.

23.

Glioma-derived extracellular vesicles selectively suppress immune responses.

Hellwinkel JE, Redzic JS, Harland TA, Gunaydin D, Anchordoquy TJ, Graner MW.

Neuro Oncol. 2016 Apr;18(4):497-506. doi: 10.1093/neuonc/nov170. Epub 2015 Sep 18.

24.

The unfolded protein response in glioblastomas: targetable or trouble?

Graner MW.

Future Sci OA. 2015 Sep 1;1(2):FSO45. doi: 10.4155/fso.15.45. eCollection 2015 Sep. Review.

25.

Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation.

Schlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep G.

Oncotarget. 2015 Sep 8;6(26):22836-56.

26.

Biological properties of extracellular vesicles and their physiological functions.

Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M, Kralj-Iglic V, Krämer-Albers EM, Laitinen S, Lässer C, Lener T, Ligeti E, Linē A, Lipps G, Llorente A, Lötvall J, Manček-Keber M, Marcilla A, Mittelbrunn M, Nazarenko I, Nolte-'t Hoen EN, Nyman TA, O'Driscoll L, Olivan M, Oliveira C, Pállinger É, Del Portillo HA, Reventós J, Rigau M, Rohde E, Sammar M, Sánchez-Madrid F, Santarém N, Schallmoser K, Ostenfeld MS, Stoorvogel W, Stukelj R, Van der Grein SG, Vasconcelos MH, Wauben MH, De Wever O.

J Extracell Vesicles. 2015 May 14;4:27066. doi: 10.3402/jev.v4.27066. eCollection 2015.

27.

Endoplasmic reticulum chaperones and their roles in the immunogenicity of cancer vaccines.

Graner MW, Lillehei KO, Katsanis E.

Front Oncol. 2015 Jan 6;4:379. doi: 10.3389/fonc.2014.00379. eCollection 2014. Review.

28.

A novel tuberculosis antigen identified from human tuberculosis granulomas.

Yu Y, Jin D, Hu S, Zhang Y, Zheng X, Zheng J, Liao M, Chen X, Graner M, Liu H, Jin Q.

Mol Cell Proteomics. 2015 Apr;14(4):1093-103. doi: 10.1074/mcp.M114.045237. Epub 2015 Jan 20.

29.

Ectopic fat depots and left ventricular function in nondiabetic men with nonalcoholic fatty liver disease.

Granér M, Nyman K, Siren R, Pentikäinen MO, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Nieminen MS, Taskinen MR.

Circ Cardiovasc Imaging. 2014 Dec 30;8(1). pii: e001979. doi: 10.1161/CIRCIMAGING.114.001979. Print 2015 Jan.

PMID:
25550397
30.

Biodistribution and delivery efficiency of unmodified tumor-derived exosomes.

Smyth T, Kullberg M, Malik N, Smith-Jones P, Graner MW, Anchordoquy TJ.

J Control Release. 2015 Feb 10;199:145-55. doi: 10.1016/j.jconrel.2014.12.013. Epub 2014 Dec 16.

31.

Exosome proteomics reveals transcriptional regulator proteins with potential to mediate downstream pathways.

Ung TH, Madsen HJ, Hellwinkel JE, Lencioni AM, Graner MW.

Cancer Sci. 2014 Nov;105(11):1384-92. doi: 10.1111/cas.12534. Epub 2014 Oct 9. Review.

32.

Surface functionalization of exosomes using click chemistry.

Smyth T, Petrova K, Payton NM, Persaud I, Redzic JS, Graner MW, Smith-Jones P, Anchordoquy TJ.

Bioconjug Chem. 2014 Oct 15;25(10):1777-84. doi: 10.1021/bc500291r. Epub 2014 Sep 30.

33.

Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro.

Smyth TJ, Redzic JS, Graner MW, Anchordoquy TJ.

Biochim Biophys Acta. 2014 Nov;1838(11):2954-65. doi: 10.1016/j.bbamem.2014.07.026. Epub 2014 Aug 4.

34.

The unfolded protein response in glioblastomas: passing the stress test.

Graner MW.

CNS Oncol. 2013 Nov;2(6):469-72. doi: 10.2217/cns.13.50. No abstract available.

35.

Cardiac steatosis in patients with dilated cardiomyopathy.

Granér M, Pentikäinen MO, Nyman K, Siren R, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Nieminen MS, Petzold M, Taskinen MR.

Heart. 2014 Jul;100(14):1107-12. doi: 10.1136/heartjnl-2013-304961. Epub 2014 Apr 24.

PMID:
24763492
36.

Glioblastoma extracellular vesicles: reservoirs of potential biomarkers.

Redzic JS, Ung TH, Graner MW.

Pharmgenomics Pers Med. 2014 Feb 13;7:65-77. doi: 10.2147/PGPM.S39768. eCollection 2014. Review.

37.

Electrocardiographic changes associated with insulin resistance.

Granér M, Pentikäinen MO, Siren R, Nyman K, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Nieminen MS, Taskinen MR.

Nutr Metab Cardiovasc Dis. 2014 Mar;24(3):315-20. doi: 10.1016/j.numecd.2013.09.013. Epub 2013 Nov 1.

PMID:
24462049
38.

Gamma interferon immunospot assay of pleural effusion mononuclear cells for diagnosis of tuberculous pleurisy.

Liao M, Yang Q, Zhang J, Zhang M, Deng Q, Liu H, Graner MW, Kornfeld H, Zhou B, Chen X.

Clin Vaccine Immunol. 2014 Mar;21(3):347-53. doi: 10.1128/CVI.00680-13. Epub 2014 Jan 3.

39.

Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.

Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G.

Mol Carcinog. 2015 Jul;54(7):554-65. doi: 10.1002/mc.22124. Epub 2013 Dec 17.

40.

Cardiac steatosis and left ventricular function in men with metabolic syndrome.

Nyman K, Granér M, Pentikäinen MO, Lundbom J, Hakkarainen A, Sirén R, Nieminen MS, Taskinen MR, Lundbom N, Lauerma K.

J Cardiovasc Magn Reson. 2013 Nov 14;15:103. doi: 10.1186/1532-429X-15-103.

41.

Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells.

Epple LM, Dodd RD, Merz AL, Dechkovskaia AM, Herring M, Winston BA, Lencioni AM, Russell RL, Madsen H, Nega M, Dusto NL, White J, Bigner DD, Nicchitta CV, Serkova NJ, Graner MW.

PLoS One. 2013 Aug 15;8(8):e73267. doi: 10.1371/journal.pone.0073267. eCollection 2013.

42.

Extracellular vesicles secreted from cancer cell lines stimulate secretion of MMP-9, IL-6, TGF-β1 and EMMPRIN.

Redzic JS, Kendrick AA, Bahmed K, Dahl KD, Pearson CG, Robinson WA, Robinson SE, Graner MW, Eisenmesser EZ.

PLoS One. 2013 Aug 1;8(8):e71225. doi: 10.1371/journal.pone.0071225. Print 2013.

43.

Prolonged remission of advanced bronchoalveolar adenocarcinoma in a dog treated with autologous, tumour-derived chaperone-rich cell lysate (CRCL) vaccine.

Epple LM, Bemis LT, Cavanaugh RP, Skope A, Mayer-Sonnenfeld T, Frank C, Olver CS, Lencioni AM, Dusto NL, Tal A, Har-Noy M, Lillehei KO, Katsanis E, Graner MW.

Int J Hyperthermia. 2013 Aug;29(5):390-8. doi: 10.3109/02656736.2013.800997. Epub 2013 Jun 20.

PMID:
23786302
45.

The 'peptidome' of tumour-derived chaperone-rich cell lysate anti-cancer vaccines reveals potential tumour antigens that stimulate tumour immunity.

Graner MW, Romanoski A, Katsanis E.

Int J Hyperthermia. 2013 Aug;29(5):380-9. doi: 10.3109/02656736.2013.793406. Epub 2013 May 31.

PMID:
23725202
46.

Diagnostic efficacy of myeloperoxidase to identify acute coronary syndrome in subjects with chest pain.

Granér M, Tikkanen E, Rimpilä O, Tikkanen H, Ripatti S, Lokki ML, Nieminen MS, Taskinen MR, Sinisalo J.

Ann Med. 2013 Jun;45(4):322-7. doi: 10.3109/07853890.2013.783996. Epub 2013 May 8.

PMID:
23651064
47.

Cardiac steatosis associates with visceral obesity in nondiabetic obese men.

Granér M, Siren R, Nyman K, Lundbom J, Hakkarainen A, Pentikäinen MO, Lauerma K, Lundbom N, Adiels M, Nieminen MS, Taskinen MR.

J Clin Endocrinol Metab. 2013 Mar;98(3):1189-97. doi: 10.1210/jc.2012-3190. Epub 2013 Feb 15.

PMID:
23418318
48.

Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles.

Epple LM, Griffiths SG, Dechkovskaia AM, Dusto NL, White J, Ouellette RJ, Anchordoquy TJ, Bemis LT, Graner MW.

PLoS One. 2012;7(7):e42064. doi: 10.1371/journal.pone.0042064. Epub 2012 Jul 27.

49.

Helical computerized tomography and NT-proBNP for screening of right ventricular overload on admission and at long term follow-up of acute pulmonary embolism.

Laiho MK, Harjola VP, Graner M, Piilonen A, Raade M, Mustonen P.

Scand J Trauma Resusc Emerg Med. 2012 May 4;20:33. doi: 10.1186/1757-7241-20-33.

50.

CD19(+)CD1d(+)CD5(+) B cell frequencies are increased in patients with tuberculosis and suppress Th17 responses.

Zhang M, Zheng X, Zhang J, Zhu Y, Zhu X, Liu H, Zeng M, Graner MW, Zhou B, Chen X.

Cell Immunol. 2012;274(1-2):89-97. doi: 10.1016/j.cellimm.2012.01.007. Epub 2012 Feb 6.

PMID:
22361174

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