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Items: 5


Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity.

Cazaux M, Grandjean CL, Lemaître F, Garcia Z, Beck RJ, Milo I, Postat J, Beltman JB, Cheadle EJ, Bousso P.

J Exp Med. 2019 May 6;216(5):1038-1049. doi: 10.1084/jem.20182375. Epub 2019 Apr 1.


Increased TCR signal strength in DN thymocytes promotes development of gut TCRαβ(+)CD8αα(+) intraepithelial lymphocytes.

Grandjean CL, Sumaria N, Martin S, Pennington DJ.

Sci Rep. 2017 Sep 6;7(1):10659. doi: 10.1038/s41598-017-09368-x.


Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells.

Sumaria N, Grandjean CL, Silva-Santos B, Pennington DJ.

Cell Rep. 2017 Jun 20;19(12):2469-2476. doi: 10.1016/j.celrep.2017.05.071.


Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals.

Ryan PL, Sumaria N, Holland CJ, Bradford CM, Izotova N, Grandjean CL, Jawad AS, Bergmeier LA, Pennington DJ.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14378-14383. Epub 2016 Nov 28.


Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies.

Grandjean CL, Montalvao F, Celli S, Michonneau D, Breart B, Garcia Z, Perro M, Freytag O, Gerdes CA, Bousso P.

Sci Rep. 2016 Oct 4;6:34382. doi: 10.1038/srep34382.

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