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Items: 1 to 50 of 81

1.

Differential assembly of Rous sarcoma virus tetrameric and octameric intasomes is regulated by the C-terminal domain and tail region of integrase.

Bera S, Pandey KK, Aihara H, Grandgenett DP.

J Biol Chem. 2018 Oct 19;293(42):16440-16452. doi: 10.1074/jbc.RA118.004768. Epub 2018 Sep 5.

PMID:
30185621
2.

Oligomerization of Retrovirus Integrases.

Grandgenett DP, Aihara H.

Subcell Biochem. 2018;88:211-243. doi: 10.1007/978-981-10-8456-0_10. Review.

PMID:
29900499
3.

A C-terminal "Tail" Region in the Rous Sarcoma Virus Integrase Provides High Plasticity of Functional Integrase Oligomerization during Intasome Assembly.

Pandey KK, Bera S, Shi K, Aihara H, Grandgenett DP.

J Biol Chem. 2017 Mar 24;292(12):5018-5030. doi: 10.1074/jbc.M116.773382. Epub 2017 Feb 8.

4.

Crystal structure of the Rous sarcoma virus intasome.

Yin Z, Shi K, Banerjee S, Pandey KK, Bera S, Grandgenett DP, Aihara H.

Nature. 2016 Feb 18;530(7590):362-6. doi: 10.1038/nature16950.

5.

Multifunctional facets of retrovirus integrase.

Grandgenett DP, Pandey KK, Bera S, Aihara H.

World J Biol Chem. 2015 Aug 26;6(3):83-94. doi: 10.4331/wjbc.v6.i3.83. Review.

6.

Rous sarcoma virus synaptic complex capable of concerted integration is kinetically trapped by human immunodeficiency virus integrase strand transfer inhibitors.

Pandey KK, Bera S, Korolev S, Campbell M, Yin Z, Aihara H, Grandgenett DP.

J Biol Chem. 2014 Jul 11;289(28):19648-58. doi: 10.1074/jbc.M114.573311. Epub 2014 May 28.

7.

A possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA binding.

Shi K, Pandey KK, Bera S, Vora AC, Grandgenett DP, Aihara H.

PLoS One. 2013;8(2):e56892. doi: 10.1371/journal.pone.0056892. Epub 2013 Feb 22.

8.

The HIV-1 integrase monomer induces a specific interaction with LTR DNA for concerted integration.

Pandey KK, Bera S, Grandgenett DP.

Biochemistry. 2011 Nov 15;50(45):9788-96. doi: 10.1021/bi201247f. Epub 2011 Oct 19.

9.

HIV-1 integrase strand transfer inhibitors stabilize an integrase-single blunt-ended DNA complex.

Bera S, Pandey KK, Vora AC, Grandgenett DP.

J Mol Biol. 2011 Jul 29;410(5):831-46. doi: 10.1016/j.jmb.2011.01.043. Epub 2011 Feb 3.

10.

Physical trapping of HIV-1 synaptic complex by different structural classes of integrase strand transfer inhibitors.

Pandey KK, Bera S, Vora AC, Grandgenett DP.

Biochemistry. 2010 Sep 28;49(38):8376-87. doi: 10.1021/bi100514s.

11.

HIV-1 Integrase Strand Transfer Inhibitors: Novel Insights into their Mechanism of Action.

Pandey KK, Grandgenett DP.

Retrovirology (Auckl). 2008 Nov 5;2:11-16.

12.

Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration.

Bera S, Pandey KK, Vora AC, Grandgenett DP.

J Mol Biol. 2009 May 29;389(1):183-98. doi: 10.1016/j.jmb.2009.04.007. Epub 2009 Apr 9.

13.

Biochemical and biophysical analyses of concerted (U5/U3) integration.

Grandgenett DP, Bera S, Pandey KK, Vora AC, Zahm J, Sinha S.

Methods. 2009 Apr;47(4):229-36. doi: 10.1016/j.ymeth.2008.11.002. Epub 2008 Nov 29.

14.

Mechanisms of human immunodeficiency virus type 1 concerted integration related to strand transfer inhibition and drug resistance.

Zahm JA, Bera S, Pandey KK, Vora A, Stillmock K, Hazuda D, Grandgenett DP.

Antimicrob Agents Chemother. 2008 Sep;52(9):3358-68. doi: 10.1128/AAC.00271-08. Epub 2008 Jun 30.

15.

Inhibition of human immunodeficiency virus type 1 concerted integration by strand transfer inhibitors which recognize a transient structural intermediate.

Pandey KK, Bera S, Zahm J, Vora A, Stillmock K, Hazuda D, Grandgenett DP.

J Virol. 2007 Nov;81(22):12189-99. Epub 2007 Sep 5.

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17.

Synaptic complex formation of two retrovirus DNA attachment sites by integrase: a fluorescence energy transfer study.

Bera S, Vora AC, Chiu R, Heyduk T, Grandgenett DP.

Biochemistry. 2005 Nov 22;44(46):15106-14.

PMID:
16285714
19.

Symmetrical recognition of cellular DNA target sequences during retroviral integration.

Grandgenett DP.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5903-4. Epub 2005 Apr 19. No abstract available.

20.

A novel structure of DNA repair protein RecO from Deinococcus radiodurans.

Makharashvili N, Koroleva O, Bera S, Grandgenett DP, Korolev S.

Structure. 2004 Oct;12(10):1881-9.

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25.

Retrovirus DNA termini bound by integrase communicate in trans for full-site integration in vitro.

McCord M, Chiu R, Vora AC, Grandgenett DP.

Virology. 1999 Jul 5;259(2):392-401.

26.

Purification of recombinant Rous sarcoma virus integrase possessing physical and catalytic properties similar to virion-derived integrase.

McCord M, Stahl SJ, Mueser TC, Hyde CC, Vora AC, Grandgenett DP.

Protein Expr Purif. 1998 Nov;14(2):167-77.

PMID:
9790878
27.

Avian retrovirus U3 and U5 DNA inverted repeats. Role Of nonsymmetrical nucleotides in promoting full-site integration by purified virion and bacterial recombinant integrases.

Vora AC, Chiu R, McCord M, Goodarzi G, Stahl SJ, Mueser TC, Hyde CC, Grandgenett DP.

J Biol Chem. 1997 Sep 19;272(38):23938-45.

28.

Host site selection for concerted integration by human immunodeficiency virus type-1 virions in vitro.

Goodarzi G, Chiu R, Brackmann K, Kohn K, Pommier Y, Grandgenett DP.

Virology. 1997 May 12;231(2):210-7.

30.

Efficient concerted integration of retrovirus-like DNA in vitro by avian myeloblastosis virus integrase.

Vora AC, McCord M, Fitzgerald ML, Inman RB, Grandgenett DP.

Nucleic Acids Res. 1994 Oct 25;22(21):4454-61.

31.

Retroviral integration: in vitro host site selection by avian integrase.

Fitzgerald ML, Grandgenett DP.

J Virol. 1994 Jul;68(7):4314-21.

32.

Folding of the multidomain human immunodeficiency virus type-I integrase.

Grandgenett DP, Goodarzi G.

Protein Sci. 1994 Jun;3(6):888-97.

33.

Comparison of DNA binding and integration half-site selection by avian myeloblastosis virus integrase.

Grandgenett DP, Inman RB, Vora AC, Fitzgerald ML.

J Virol. 1993 May;67(5):2628-36.

34.

Concerted integration of viral DNA termini by purified avian myeloblastosis virus integrase.

Fitzgerald ML, Vora AC, Zeh WG, Grandgenett DP.

J Virol. 1992 Nov;66(11):6257-63.

35.

Characterization of a stable eukaryotic cell line expressing the Rous sarcoma virus integrase.

Mumm SR, Hippenmeyer PJ, Grandgenett DP.

Virology. 1992 Aug;189(2):500-10.

PMID:
1322585
36.

v-Src enhances phosphorylation at Ser-282 of the Rous sarcoma virus integrase.

Mumm SR, Horton R, Grandgenett DP.

J Virol. 1992 Apr;66(4):1995-9.

37.

Development of an acid-soluble assay for measuring retrovirus integrase 3'-OH terminal nuclease activity.

Fitzgerald ML, Vora AC, Grandgenett DP.

Anal Biochem. 1991 Jul;196(1):19-23.

PMID:
1888032
38.

Retrovirus integrase: identification of a potential leucine zipper motif.

Lin TH, Grandgenett DP.

Protein Eng. 1991 Apr;4(4):435-41.

PMID:
1652750
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42.

Rearrangements in unintegrated retroviral DNA are complex and are the result of multiple genetic determinants.

Olsen JC, Bova-Hill C, Grandgenett DP, Quinn TP, Manfredi JP, Swanstrom R.

J Virol. 1990 Nov;64(11):5475-84.

43.

Unraveling retrovirus integration.

Grandgenett DP, Mumm SR.

Cell. 1990 Jan 12;60(1):3-4. Review. No abstract available.

PMID:
2403842
44.

Avian retrovirus integration protein: structure-functional analysis of viable mutants.

Quinn TP, Grandgenett DP.

Virology. 1989 Dec;173(2):478-88.

PMID:
2556839
45.
46.
47.

Nuclease mechanism of the avian retrovirus pp32 endonuclease.

Grandgenett DP, Vora AC, Swanstrom R, Olsen JC.

J Virol. 1986 Jun;58(3):970-4.

48.
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50.

Requirement of the avian retrovirus pp32 DNA binding protein domain for replication.

Hippenmeyer PJ, Grandgenett DP.

Virology. 1984 Sep;137(2):358-70.

PMID:
6091334

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