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Items: 11


Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands.

Henriksen L, Grandal MV, Knudsen SL, van Deurs B, Grøvdal LM.

PLoS One. 2013;8(3):e58148. doi: 10.1371/journal.pone.0058148. Epub 2013 Mar 5.


Cell-surface metalloprotease ADAM12 is internalized by a clathrin- and Grb2-dependent mechanism.

Stautz D, Leyme A, Grandal MV, Albrechtsen R, van Deurs B, Wewer U, Kveiborg M.

Traffic. 2012 Nov;13(11):1532-46. doi: 10.1111/j.1600-0854.2012.01405.x. Epub 2012 Sep 10.


Differential roles of Grb2 and AP-2 in p38 MAPK- and EGF-induced EGFR internalization.

Grandal MV, Grøvdal LM, Henriksen L, Andersen MH, Holst MR, Madshus IH, van Deurs B.

Traffic. 2012 Apr;13(4):576-85. doi: 10.1111/j.1600-0854.2011.01322.x. Epub 2012 Jan 17.


EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells.

Grøvdal LM, Kim J, Holst MR, Knudsen SL, Grandal MV, van Deurs B.

Cell Signal. 2012 Jan;24(1):296-301. doi: 10.1016/j.cellsig.2011.09.012. Epub 2011 Sep 17.


Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis.

Billeskov R, Grandal MV, Poulsen C, Christensen JP, Winther N, Vingsbo-Lundberg C, Hoang TT, van Deurs B, Song YH, Aagaard C, Andersen P, Dietrich J.

Eur J Immunol. 2010 May;40(5):1342-54. doi: 10.1002/eji.200939830. Erratum in: Eur J Immunol. 2011 Mar;41(3):873.


Differential effects of EGFR ligands on endocytic sorting of the receptor.

Roepstorff K, Grandal MV, Henriksen L, Knudsen SL, Lerdrup M, Grøvdal L, Willumsen BM, van Deurs B.

Traffic. 2009 Aug;10(8):1115-27. doi: 10.1111/j.1600-0854.2009.00943.x. Epub 2009 May 19.


Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits.

Kazazic M, Bertelsen V, Pedersen KW, Vuong TT, Grandal MV, Rødland MS, Traub LM, Stang E, Madshus IH.

Traffic. 2009 Feb;10(2):235-45. doi: 10.1111/j.1600-0854.2008.00858.x. Epub 2008 Nov 20.


Epidermal growth factor receptor and cancer: control of oncogenic signalling by endocytosis.

Grandal MV, Madshus IH.

J Cell Mol Med. 2008 Sep-Oct;12(5A):1527-34. doi: 10.1111/j.1582-4934.2008.00298.x. Epub 2008 Mar 4. Review.


Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

Lerdrup M, Bruun S, Grandal MV, Roepstorff K, Kristensen MM, Hommelgaard AM, van Deurs B.

Mol Biol Cell. 2007 Sep;18(9):3656-66. Epub 2007 Jul 11.


Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility.

Larsen AB, Pedersen MW, Stockhausen MT, Grandal MV, van Deurs B, Poulsen HS.

Mol Cancer Res. 2007 Mar;5(3):283-93.


EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes.

Grandal MV, Zandi R, Pedersen MW, Willumsen BM, van Deurs B, Poulsen HS.

Carcinogenesis. 2007 Jul;28(7):1408-17. Epub 2007 Mar 19.


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