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Items: 18

1.

Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo.

Kurash JK, Lei H, Shen Q, Marston WL, Granda BW, Fan H, Wall D, Li E, Gaudet F.

Mol Cell. 2008 Feb 15;29(3):392-400. doi: 10.1016/j.molcel.2007.12.025.

2.

Interaction of triazolam and ketoconazole in P-glycoprotein-deficient mice.

von Moltke LL, Granda BW, Grassi JM, Perloff MD, Vishnuvardhan D, Greenblatt DJ.

Drug Metab Dispos. 2004 Aug;32(8):800-4.

PMID:
15258104
3.

Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone.

Greenblatt DJ, von Moltke LL, Harmatz JS, Fogelman SM, Chen G, Graf JA, Mertzanis P, Byron S, Culm KE, Granda BW, Daily JP, Shader RI.

J Clin Pharmacol. 2003 Apr;43(4):414-22.

PMID:
12723462
4.

Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors.

Tran TH, Von Moltke LL, Venkatakrishnan K, Granda BW, Gibbs MA, Obach RS, Harmatz JS, Greenblatt DJ.

Drug Metab Dispos. 2002 Dec;30(12):1441-5.

PMID:
12433817
5.

In vitro, pharmacokinetic, and pharmacodynamic interactions of ketoconazole and midazolam in the rat.

Kotegawa T, Laurijssens BE, Von Moltke LL, Cotreau MM, Perloff MD, Venkatakrishnan K, Warrington JS, Granda BW, Harmatz JS, Greenblatt DJ.

J Pharmacol Exp Ther. 2002 Sep;302(3):1228-37.

PMID:
12183684
6.

Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram.

von Moltke LL, Greenblatt DJ, Giancarlo GM, Granda BW, Harmatz JS, Shader RI.

Drug Metab Dispos. 2001 Aug;29(8):1102-9.

PMID:
11454728
7.

Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.

Giancarlo GM, Venkatakrishnan K, Granda BW, von Moltke LL, Greenblatt DJ.

Eur J Clin Pharmacol. 2001 Apr;57(1):31-6.

PMID:
11372587
8.

Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors.

von Moltke LL, Greenblatt DJ, Granda BW, Giancarlo GM, Duan SX, Daily JP, Harmatz JS, Shader RI.

J Clin Pharmacol. 2001 Jan;41(1):85-91.

PMID:
11225565
9.

Inhibition of human cytochrome P450 isoforms in vitro by zafirlukast.

Shader RI, Granda BW, von Moltke LL, Giancarlo GM, Greenblatt DJ.

Biopharm Drug Dispos. 1999 Nov;20(8):385-8.

PMID:
10870095
10.

In vitro metabolism of trazodone by CYP3A: inhibition by ketoconazole and human immunodeficiency viral protease inhibitors.

Zalma A, von Moltke LL, Granda BW, Harmatz JS, Shader RI, Greenblatt DJ.

Biol Psychiatry. 2000 Apr 1;47(7):655-61.

PMID:
10745059
11.

Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects.

von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Venkatakrishnan K, Duan SX, Fogelman SM, Harmatz JS, Shader RI.

Biol Psychiatry. 1999 Sep 15;46(6):839-49.

PMID:
10494454
12.

Analysis of ritonavir in plasma/serum and tissues by high-performance liquid chromatography.

Granda BW, Giancarlo GM, von Moltke LL, Greenblatt DJ.

J Pharmacol Toxicol Methods. 1998 Nov;40(4):235-9.

PMID:
10465159
13.

Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions.

von Moltke LL, Greenblatt DJ, Granda BW, Grassi JM, Schmider J, Harmatz JS, Shader RI.

Psychopharmacology (Berl). 1999 Jul;145(1):113-22.

PMID:
10445380
14.

Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations.

Von Moltke LL, Greenblatt DJ, Granda BW, Duan SX, Grassi JM, Venkatakrishnan K, Harmatz JS, Shader RI.

Br J Clin Pharmacol. 1999 Jul;48(1):89-97.

15.

Gepirone and 1-(2-pyrimidinyl)-piperazine in vitro: human cytochromes mediating transformation and cytochrome inhibitory effects.

von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Fogelman SM, Harmatz JS, Kramer SJ, Fabre LF, Shader RI.

Psychopharmacology (Berl). 1998 Dec;140(3):293-9.

PMID:
9877009
16.

Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.

von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Venkatakrishnan K, Schmider J, Harmatz JS, Shader RI.

J Pharm Pharmacol. 1998 Sep;50(9):997-1004.

PMID:
9811160
17.

Appetite suppressant drugs as inhibitors of human cytochromes P450: in vitro inhibition of P450-2D6 by D- and L-fenfluramine, but not phentermine.

von Moltke LL, Greenblatt DJ, Ciraulo DA, Grassi JM, Granda BW, Duan SX, Harmatz JS, Shader RI.

J Clin Psychopharmacol. 1998 Aug;18(4):338-41.

PMID:
9690701
18.

Protease inhibitors as inhibitors of human cytochromes P450: high risk associated with ritonavir.

von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Duan SX, Fogelman SM, Daily JP, Harmatz JS, Shader RI.

J Clin Pharmacol. 1998 Feb;38(2):106-11.

PMID:
9549640

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