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Items: 1 to 50 of 156

1.

Sourcing the immune system to induce immunogenic cell death in Kras-colorectal cancer cells.

Cirone M, Lotti LV, Granato M, Renzo LD, Biunno I, Cattaneo M, Verginelli F, Vespa S, Davies D, Wells V, Mariani-Costantini R, Mallucci L.

Br J Cancer. 2019 Oct;121(9):768-775. doi: 10.1038/s41416-019-0561-z. Epub 2019 Sep 27.

PMID:
31558803
2.

Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization.

Granato M, Gilardini Montani MS, Zompetta C, Santarelli R, Gonnella R, Romeo MA, D'Orazi G, Faggioni A, Cirone M.

Biomolecules. 2019 Sep 12;9(9). pii: E482. doi: 10.3390/biom9090482.

3.

A Five-Level, 1-MHz, Class-D Ultrasonic Driver for Guided-Wave Transducer Arrays.

Giannelli P, Bulletti A, Granato M, Frattini G, Calabrese G, Capineri L.

IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Oct;66(10):1616-1624. doi: 10.1109/TUFFC.2019.2924943. Epub 2019 Jun 26.

PMID:
31251181
4.

Kaposi Sarcoma Herpes Virus (KSHV) infection inhibits macrophage formation and survival by counteracting Macrophage Colony-Stimulating Factor (M-CSF)-induced increase of Reactive Oxygen Species (ROS), c-Jun N-terminal kinase (JNK) phosphorylation and autophagy.

Gilardini Montani MS, Falcinelli L, Santarelli R, Romeo MA, Granato M, Faggioni A, Cirone M.

Int J Biochem Cell Biol. 2019 Sep;114:105560. doi: 10.1016/j.biocel.2019.06.008. Epub 2019 Jun 17.

PMID:
31220583
5.

Optic nerve regeneration in larval zebrafish exhibits spontaneous capacity for retinotopic but not tectum specific axon targeting.

Harvey BM, Baxter M, Granato M.

PLoS One. 2019 Jun 20;14(6):e0218667. doi: 10.1371/journal.pone.0218667. eCollection 2019.

6.

Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences.

Cirone M, Gilardini Montani MS, Granato M, Garufi A, Faggioni A, D'Orazi G.

J Exp Clin Cancer Res. 2019 Jun 14;38(1):262. doi: 10.1186/s13046-019-1275-z. Review.

7.

The ubiquitin ligase PHR promotes directional regrowth of spinal zebrafish axons.

Bremer J, Marsden KC, Miller A, Granato M.

Commun Biol. 2019 May 22;2:195. doi: 10.1038/s42003-019-0434-2. eCollection 2019.

8.

Mutant p53, Stabilized by Its Interplay with HSP90, Activates a Positive Feed-Back Loop Between NRF2 and p62 that Induces Chemo-Resistance to Apigenin in Pancreatic Cancer Cells.

Gilardini Montani MS, Cecere N, Granato M, Romeo MA, Falcinelli L, Ciciarelli U, D'Orazi G, Faggioni A, Cirone M.

Cancers (Basel). 2019 May 22;11(5). pii: E703. doi: 10.3390/cancers11050703.

9.

Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish.

Randlett O, Haesemeyer M, Forkin G, Shoenhard H, Schier AF, Engert F, Granato M.

Curr Biol. 2019 Apr 22;29(8):1337-1345.e4. doi: 10.1016/j.cub.2019.02.039. Epub 2019 Apr 4.

PMID:
30955936
10.

Dynein promotes sustained axonal growth and Schwann cell remodeling early during peripheral nerve regeneration.

Ducommun Priest M, Navarro MF, Bremer J, Granato M.

PLoS Genet. 2019 Feb 19;15(2):e1007982. doi: 10.1371/journal.pgen.1007982. eCollection 2019 Feb.

11.

STAT3 phosphorylation affects p53/p21 axis and KSHV lytic cycle activation.

Santarelli R, Carillo V, Romeo MA, Gaeta A, Nazzari C, Gonnella R, Granato M, D'Orazi G, Faggioni A, Cirone M.

Virology. 2019 Feb;528:137-143. doi: 10.1016/j.virol.2018.12.015. Epub 2019 Jan 5.

PMID:
30616203
12.

Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1.

Granato M, Gilardini Montani MS, Angiolillo C, D'Orazi G, Faggioni A, Cirone M.

Viruses. 2018 Dec 24;11(1). pii: E8. doi: 10.3390/v11010008.

13.

Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stress.

Romeo MA, Masuelli L, Gaeta A, Nazzari C, Granato M, Gilardini Montani MS, Faggioni A, Cirone M.

J Gen Virol. 2019 Jan;100(1):89-98. doi: 10.1099/jgv.0.001176. Epub 2018 Nov 14.

PMID:
30427305
14.

Associations between Attention-Deficit Hyperactivity Disorder (ADHD) Treatment and Patient Nutritional Status and Height.

Granato MF, Ferraro AA, Lellis DM, Casella EB.

Behav Neurol. 2018 Oct 2;2018:7341529. doi: 10.1155/2018/7341529. eCollection 2018.

15.

EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation.

Gilardini Montani MS, Santarelli R, Granato M, Gonnella R, Torrisi MR, Faggioni A, Cirone M.

Autophagy. 2019 Apr;15(4):652-667. doi: 10.1080/15548627.2018.1536530. Epub 2018 Oct 23.

16.

EBV up-regulates PD-L1 on the surface of primary monocytes by increasing ROS and activating TLR signaling and STAT3.

Gilardini Montani MS, Santarelli R, Falcinelli L, Gonnella R, Granato M, Di Renzo L, Cuomo L, Vitillo M, Faggioni A, Cirone M.

J Leukoc Biol. 2018 Oct;104(4):821-832. doi: 10.1002/JLB.2A0118-029RR. Epub 2018 Jul 24.

PMID:
30040158
17.

Fonsecaea pedrosoi Sclerotic Cells: Secretion of Aspartic-Type Peptidase and Susceptibility to Peptidase Inhibitors.

Palmeira VF, Goulart FRV, Granato MQ, Alviano DS, Alviano CS, Kneipp LF, Santos ALS.

Front Microbiol. 2018 Jun 29;9:1383. doi: 10.3389/fmicb.2018.01383. eCollection 2018.

18.

The synaptic receptor Lrp4 promotes peripheral nerve regeneration.

Gribble KD, Walker LJ, Saint-Amant L, Kuwada JY, Granato M.

Nat Commun. 2018 Jun 19;9(1):2389. doi: 10.1038/s41467-018-04806-4.

19.

A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making.

Jain RA, Wolman MA, Marsden KC, Nelson JC, Shoenhard H, Echeverry FA, Szi C, Bell H, Skinner J, Cobbs EN, Sawada K, Zamora AD, Pereda AE, Granato M.

Curr Biol. 2018 May 7;28(9):1357-1369.e5. doi: 10.1016/j.cub.2018.03.025. Epub 2018 Apr 19.

20.

A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold.

Marsden KC, Jain RA, Wolman MA, Echeverry FA, Nelson JC, Hayer KE, Miltenberg B, Pereda AE, Granato M.

Cell Rep. 2018 Apr 17;23(3):878-887. doi: 10.1016/j.celrep.2018.03.095.

21.

Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death.

Granato M, Gilardini Montani MS, Santarelli R, D'Orazi G, Faggioni A, Cirone M.

J Exp Clin Cancer Res. 2017 Nov 28;36(1):167. doi: 10.1186/s13046-017-0632-z.

22.

Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice.

Masuelli L, Granato M, Benvenuto M, Mattera R, Bernardini R, Mattei M, d'Amati G, D'Orazi G, Faggioni A, Bei R, Cirone M.

Oncoimmunology. 2017 Jul 31;6(11):e1356151. doi: 10.1080/2162402X.2017.1356151. eCollection 2017.

23.

Low-Frequency Pulsed Electromagnetic Field Is Able to Modulate miRNAs in an Experimental Cell Model of Alzheimer's Disease

Capelli E, Torrisi F, Venturini L, Granato M, Fassina L, Lupo GFD, Ricevuti G.

J Healthc Eng. 2017;2017. doi: 10.1155/2017/2530270.

24.

Low-Frequency Pulsed Electromagnetic Field Is Able to Modulate miRNAs in an Experimental Cell Model of Alzheimer's Disease.

Capelli E, Torrisi F, Venturini L, Granato M, Fassina L, Lupo GFD, Ricevuti G.

J Healthc Eng. 2017;2017:2530270. doi: 10.1155/2017/2530270. Epub 2017 May 2.

25.

Reuse of wastewaters on dyeing of polyester fabric with encapsulated disperse dye.

Granato MA, Gaspar TM, Alves AF, de Souza AAU, Ulson de Souza SMAG.

Environ Technol. 2019 Jan;40(4):408-417. doi: 10.1080/09593330.2017.1393017. Epub 2017 Nov 2.

PMID:
29037110
26.

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy.

Granato M, Romeo MA, Tiano MS, Santarelli R, Gonnella R, Gilardini Montani MS, Faggioni A, Cirone M.

Sci Rep. 2017 Oct 12;7(1):13052. doi: 10.1038/s41598-017-13533-7.

27.

Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation.

Granato M, Gilardini Montani MS, Romeo MA, Santarelli R, Gonnella R, D'Orazi G, Faggioni A, Cirone M.

Cell Signal. 2017 Dec;40:239-247. doi: 10.1016/j.cellsig.2017.09.020. Epub 2017 Sep 28.

PMID:
28964970
28.

Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells.

Gonnella R, Yadav S, Gilardini Montani MS, Granato M, Santarelli R, Garufi A, D'Orazi G, Faggioni A, Cirone M.

Free Radic Biol Med. 2017 Nov;112:327-335. doi: 10.1016/j.freeradbiomed.2017.08.005. Epub 2017 Aug 8.

PMID:
28801242
29.

First experience with multiple mini interview for medical school admission in Brazil: Does it work in a different cultural scenario?

Daniel-Filho DA, Pires EMSG, Paes AT, Troster EJ, Silva SCABS, Granato MF, Couto TB, Barreto JKS, Campos AH, Monte JCM, Schvartsman C.

Med Teach. 2017 Oct;39(10):1033-1039. doi: 10.1080/0142159X.2017.1342032. Epub 2017 Jul 6.

PMID:
28681649
30.

HIV Aspartic Peptidase Inhibitors Modulate Surface Molecules and Enzyme Activities Involved with Physiopathological Events in Fonsecaea pedrosoi.

Palmeira VF, Alviano DS, Braga-Silva LA, Goulart FRV, Granato MQ, Rozental S, Alviano CS, Santos ALS, Kneipp LF.

Front Microbiol. 2017 May 19;8:918. doi: 10.3389/fmicb.2017.00918. eCollection 2017.

31.

A small molecule screen identifies in vivo modulators of peripheral nerve regeneration in zebrafish.

Bremer J, Skinner J, Granato M.

PLoS One. 2017 Jun 2;12(6):e0178854. doi: 10.1371/journal.pone.0178854. eCollection 2017.

32.

A genetic basis for molecular asymmetry at vertebrate electrical synapses.

Miller AC, Whitebirch AC, Shah AN, Marsden KC, Granato M, O'Brien J, Moens CB.

Elife. 2017 May 22;6. pii: e25364. doi: 10.7554/eLife.25364.

33.

1,10-Phenanthroline-5,6-Dione-Based Compounds Are Effective in Disturbing Crucial Physiological Events of Phialophora verrucosa.

Granato MQ, Gonçalves DS, Seabra SH, McCann M, Devereux M, Dos Santos AL, Kneipp LF.

Front Microbiol. 2017 Jan 30;8:76. doi: 10.3389/fmicb.2017.00076. eCollection 2017.

34.

Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells.

Gilardini Montani MS, Granato M, Santoni C, Del Porto P, Merendino N, D'Orazi G, Faggioni A, Cirone M.

Cell Oncol (Dordr). 2017 Apr;40(2):167-180. doi: 10.1007/s13402-017-0314-z. Epub 2017 Feb 3.

PMID:
28160167
35.

Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways.

Granato M, Rizzello C, Gilardini Montani MS, Cuomo L, Vitillo M, Santarelli R, Gonnella R, D'Orazi G, Faggioni A, Cirone M.

J Nutr Biochem. 2017 Mar;41:124-136. doi: 10.1016/j.jnutbio.2016.12.011. Epub 2017 Jan 5.

PMID:
28092744
36.

Hyperglycemia triggers HIPK2 protein degradation.

Baldari S, Garufi A, Granato M, Cuomo L, Pistritto G, Cirone M, D'Orazi G.

Oncotarget. 2017 Jan 3;8(1):1190-1203. doi: 10.18632/oncotarget.13595.

37.

Myosin phosphatase Fine-tunes Zebrafish Motoneuron Position during Axonogenesis.

Bremer J, Granato M.

PLoS Genet. 2016 Nov 17;12(11):e1006440. doi: 10.1371/journal.pgen.1006440. eCollection 2016 Nov.

38.

KSHV reduces autophagy in THP-1 cells and in differentiating monocytes by decreasing CAST/calpastatin and ATG5 expression.

Santarelli R, Granato M, Pentassuglia G, Lacconi V, Gilardini Montani MS, Gonnella R, Tafani M, Torrisi MR, Faggioni A, Cirone M.

Autophagy. 2016 Dec;12(12):2311-2325. Epub 2016 Oct 7.

39.

Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma.

Granato M, Rizzello C, Romeo MA, Yadav S, Santarelli R, D'Orazi G, Faggioni A, Cirone M.

Int J Biochem Cell Biol. 2016 Oct;79:393-400. doi: 10.1016/j.biocel.2016.09.006. Epub 2016 Sep 9.

PMID:
27620077
40.

Genetic evaluation of AMPD1, CPT2, and PGYM metabolic enzymes in patients with chronic fatigue syndrome.

Maltese PE, Venturini L, Poplavskaya E, Bertelli M, Cecchin S, Granato M, Nikulina SY, Salmina A, Aksyutina N, Capelli E, Ricevuti G, Lorusso L.

Genet Mol Res. 2016 Jul 29;15(3). doi: 10.4238/gmr.15038717.

PMID:
27525900
41.

HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2.

Granato M, Zompetta C, Vescarelli E, Rizzello C, Cardi A, Valia S, Antonelli G, Marchese C, Torrisi MR, Faggioni A, Cirone M.

Sci Rep. 2016 Aug 1;6:30649. doi: 10.1038/srep30649.

42.

Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution.

Remédio L, Gribble KD, Lee JK, Kim N, Hallock PT, Delestrée N, Mentis GZ, Froemke RC, Granato M, Burden SJ.

Genes Dev. 2016 May 1;30(9):1058-69. doi: 10.1101/gad.279745.116.

43.

Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2.

Hoffman EJ, Turner KJ, Fernandez JM, Cifuentes D, Ghosh M, Ijaz S, Jain RA, Kubo F, Bill BR, Baier H, Granato M, Barresi MJ, Wilson SW, Rihel J, State MW, Giraldez AJ.

Neuron. 2016 Feb 17;89(4):725-33. doi: 10.1016/j.neuron.2015.12.039. Epub 2016 Jan 28.

44.

High glucose and hyperglycemic sera from type 2 diabetic patients impair DC differentiation by inducing ROS and activating Wnt/β-catenin and p38 MAPK.

Gilardini Montani MS, Granato M, Cuomo L, Valia S, Di Renzo L, D'Orazi G, Faggioni A, Cirone M.

Biochim Biophys Acta. 2016 Apr;1862(4):805-813. doi: 10.1016/j.bbadis.2016.01.001. Epub 2016 Jan 6.

45.

In Vivo Ca(2+) Imaging Reveals that Decreased Dendritic Excitability Drives Startle Habituation.

Marsden KC, Granato M.

Cell Rep. 2015 Dec 1;13(9):1733-40. doi: 10.1016/j.celrep.2015.10.060. Epub 2015 Nov 19.

46.

The lh3 Glycosyltransferase Directs Target-Selective Peripheral Nerve Regeneration.

Isaacman-Beck J, Schneider V, Franzini-Armstrong C, Granato M.

Neuron. 2015 Nov 18;88(4):691-703. doi: 10.1016/j.neuron.2015.10.004. Epub 2015 Nov 5.

47.

The activation of KSHV lytic cycle blocks autophagy in PEL cells.

Granato M, Santarelli R, Filardi M, Gonnella R, Farina A, Torrisi MR, Faggioni A, Cirone M.

Autophagy. 2015 Nov 2;11(11):1978-1986. doi: 10.1080/15548627.2015.1091911.

48.

Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression.

Granato M, Gilardini Montani MS, Filardi M, Faggioni A, Cirone M.

Oncotarget. 2015 Oct 6;6(30):29543-54. doi: 10.18632/oncotarget.4911.

49.

Tyrosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells.

Granato M, Chiozzi B, Filardi MR, Lotti LV, Di Renzo L, Faggioni A, Cirone M.

Cancer Lett. 2015 Oct 1;366(2):191-7. doi: 10.1016/j.canlet.2015.07.006. Epub 2015 Jul 13.

PMID:
26184999
50.

Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses.

Santarelli R, Granato M, Faggioni A, Cirone M.

J Immunol Res. 2015;2015:546063. doi: 10.1155/2015/546063. Epub 2015 May 18. Review.

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