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The hypothesis of an increased mortality following paclitaxel coated device use in peripheral vascular interventions (and the emerging era of meta-analysis based evidence).

Cortese B, Alfonso F, Pellegrini D, Sing KR, Granada JF.

Catheter Cardiovasc Interv. 2019 Nov 19. doi: 10.1002/ccd.28600. [Epub ahead of print] No abstract available.


SYNERGY Early Stent Thrombosis.

Kereiakes DJ, Granada JF.

JACC Cardiovasc Interv. 2019 Nov 11;12(21):2227-2228. doi: 10.1016/j.jcin.2019.09.009. No abstract available.


A novel supra-annular plane that predicts TAVI prosthesis anchoring in raphe-type bicuspid aortic valve disease: the LIRA plane.

Iannopollo G, Romano V, Buzzatti N, De Backer O, Søndergaard L, Merkely B, Prendergast BD, Giannini F, Colombo A, Latib A, Granada JF, Chieffo A, Montorfano M.

EuroIntervention. 2019 Oct 29. pii: EIJ-D-19-00951. doi: 10.4244/EIJ-D-19-00951. [Epub ahead of print] No abstract available.


First-in-Human Implant of the Cephea Transseptal Mitral Valve Replacement System.

Modine T, Vahl TP, Khalique OK, Coisne A, Vincent F, Montaigne D, Godart F, Van Belle E, Granada JF.

Circ Cardiovasc Interv. 2019 Sep;12(9):e008003. doi: 10.1161/CIRCINTERVENTIONS.119.008003. Epub 2019 Sep 12. No abstract available.


Experimental Evaluation of a Novel Percutaneous Transseptal Catheter-Based Mitral Valve Replacement Technology.

Vahl TP, Grogan A, Cheng Y, Yi G, von Oepen R, Khalique OK, Wallace DT, Modine T, Granada JF.

Circ Cardiovasc Interv. 2019 Sep;12(9):e008002. doi: 10.1161/CIRCINTERVENTIONS.119.008002. Epub 2019 Sep 12.


Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.

Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM.

Sci Transl Med. 2019 Aug 21;11(506). pii: eaaw7736. doi: 10.1126/scitranslmed.aaw7736.


Predictors of adverse outcomes after transcatheter mitral valve replacement.

Overtchouk P, Piazza N, Granada JF, Modine T.

Expert Rev Cardiovasc Ther. 2019 Aug;17(8):625-632. doi: 10.1080/14779072.2019.1653186. Epub 2019 Aug 14. Review.


Impact of Artificial Intelligence on Interventional Cardiology: From Decision-Making Aid to Advanced Interventional Procedure Assistance.

Sardar P, Abbott JD, Kundu A, Aronow HD, Granada JF, Giri J.

JACC Cardiovasc Interv. 2019 Jul 22;12(14):1293-1303. doi: 10.1016/j.jcin.2019.04.048. Review. Erratum in: JACC Cardiovasc Interv. 2019 Aug 26;12(16):1634.


Current concepts regarding drug dosing for peripheral stents.

Ferrone M, Cheng Y, Granada JF.

J Cardiovasc Surg (Torino). 2019 Aug;60(4):439-449. doi: 10.23736/S0021-9509.19.10995-0. Epub 2019 May 2. Review.


The Bioresorbable Vascular Scaffold Tale Epilogue: Overpromised, Underdelivered, Prematurely Degraded.

Kaluza GL, Granada JF.

JACC Cardiovasc Interv. 2019 May 27;12(10):980-982. doi: 10.1016/j.jcin.2019.03.032. Epub 2019 Apr 24. No abstract available.


In vitro mechanical behavior and in vivo healing response of a novel thin-strut ultrahigh molecular weight poly-l-lactic acid sirolimus-eluting bioresorbable coronary scaffold in normal swine.

Cheng Y, Gasior P, Ramzipoor K, Lee C, McGregor JC, Conditt GB, McAndrew T, Kaluza GL, Granada JF.

Int J Cardiol. 2019 Jul 1;286:21-28. doi: 10.1016/j.ijcard.2019.04.012. Epub 2019 Apr 4.


Rate of Drug Coating Dissolution Determines In-Tissue Drug Retention and Durability of Biological Efficacy.

Granada JF, Virmani R, Schulz-Jander D, Tunev S, Melder RJ.

J Drug Deliv. 2019 Jan 8;2019:9560592. doi: 10.1155/2019/9560592. eCollection 2019.


In vivo comparison of key quantitative parameters measured with 3D peripheral angiography, 2D peripheral quantitative angiography and intravascular ultrasound.

Zasada W, Slezak M, Pociask E, Malinowski KP, Proniewska K, Buszman P, Milewski K, Granada JF, Kaluza GL.

Int J Cardiovasc Imaging. 2019 Feb;35(2):215-223. doi: 10.1007/s10554-019-01529-5. Epub 2019 Feb 22.


Transcatheter Cardiovascular Therapeutics 2018.

Mintz GS, Stone GW, Granada JF, Mehran R, Kirtane A, Dangas G, Parikh SA, Leon MB.

Eur Heart J. 2019 Feb 14;40(7):568-571. doi: 10.1093/eurheartj/ehy896. No abstract available.


Translational Research: The Cornerstone for Medical Technology Advancement.

Tellez A, Ferrone M, Granada JF.

Toxicol Pathol. 2019 Apr;47(3):203-204. doi: 10.1177/0192623318819972. Epub 2019 Feb 11.


Achieving Health Equity by Normalizing Cardiac Care.

Pegus C, Duncan I, Greener J, Granada JF, Ahmed T.

Health Equity. 2018 Dec 28;2(1):404-411. doi: 10.1089/heq.2018.0067. eCollection 2018.


Clinical Randomized Trial Evaluating Novel, Microcrystalline, and Biocompatible Polymer Paclitaxel-Coated Balloon for the Treatment of Femoropopliteal Occlusive Disease: The BIOPAC Trial.

Buszman PP, Nowakowski P, Milewski K, Orlik B, Żurakowski A, Ludyga T, Polczyk F, Dębiński M, Jelonek M, Kachel M, Gąsior M, Granada JF, Kiesz RS, Buszman PE.

JACC Cardiovasc Interv. 2018 Dec 10;11(23):2436-2438. doi: 10.1016/j.jcin.2018.07.029. No abstract available.


Drug-Coated Balloons for In-Stent Restenosis: A Fierce Fight for a "Me-Too" Space.

Granada JF.

JACC Cardiovasc Interv. 2018 Dec 10;11(23):2378-2380. doi: 10.1016/j.jcin.2018.10.029. No abstract available.


Sustainable Antirestenosis Effect With a Low-Dose Drug-Coated Balloon: The ILLUMENATE European Randomized Clinical Trial 2-Year Results.

Brodmann M, Werner M, Meyer DR, Reimer P, Krüger K, Granada JF, Jaff MR, Schroeder H; ILLUMENATE EU RCT Investigators.

JACC Cardiovasc Interv. 2018 Dec 10;11(23):2357-2364. doi: 10.1016/j.jcin.2018.08.034.


Two-year longitudinal evaluation of a second-generation thin-strut sirolimus-eluting bioresorbable coronary scaffold with hybrid cell design in porcine coronary arteries.

Gasior P, Cheng Y, Xia J, Conditt GB, McGregor JC, Virmani R, Granada JF, Kaluza GL.

Cardiol J. 2018 Aug 29. doi: 10.5603/CJ.a2018.0095. [Epub ahead of print]


Catheter-Based Intervention of the "Forgotten" Valve: Time to Reconsider Tricuspid Valve Intervention?

Granada JF, Vahl T.

JACC Basic Transl Sci. 2018 Mar 1;3(1):80-82. doi: 10.1016/j.jacbts.2018.01.009. eCollection 2018 Feb. No abstract available.


Variation in vessel healing response after implantation of two different poly-L-lactic acid bioresorbable scaffolds: insights from optical coherence tomography.

Mitomo S, Latib A, Jabbour RJ, Demir OM, Granada JF, Colombo A.

EuroIntervention. 2018 Dec 20;14(12):e1304-e1305. doi: 10.4244/EIJ-D-18-00456. No abstract available.


Isolation of pulmonary veins using a thermoreactive implantable device with external energy transfer: Evaluation in a porcine model.

Boussy T, Vandecasteele T, Vera L, Schauvliege S, Philpott M, Clement E, van Loon G, Willenz U, Granada JF, Stone GW, Reddy VY, Van Langenhove G.

Pacing Clin Electrophysiol. 2018 Jun;41(6):603-610. doi: 10.1111/pace.13345. Epub 2018 May 4.


First in human evaluation of the vascular biocompatibility and biomechanical performance of a novel ultra high molecular weight amorphous PLLA bioresorbable scaffold in the absence of anti-proliferative drugs: Two-year imaging results in humans.

Moncada M, Delgado JA, Colombo A, Gasior P, Ramzipoor K, Estrada A, Lee C, Dokko D, Granada JF.

Catheter Cardiovasc Interv. 2018 Sep 1;92(3):E246-E253. doi: 10.1002/ccd.27444. Epub 2017 Dec 15.


The SABRE Trial (Sirolimus Angioplasty Balloon for Coronary In-Stent Restenosis): Angiographic Results and 1-Year Clinical Outcomes.

Verheye S, Vrolix M, Kumsars I, Erglis A, Sondore D, Agostoni P, Cornelis K, Janssens L, Maeng M, Slagboom T, Amoroso G, Jensen LO, Granada JF, Stella P.

JACC Cardiovasc Interv. 2017 Oct 23;10(20):2029-2037. doi: 10.1016/j.jcin.2017.06.021. Epub 2017 Sep 27.


Impact of bioresorbable versus permanent polymer on longterm vessel wall inflammation and healing: a comparative drug-eluting stent experimental study.

Wilson GJ, McGregor J, Conditt G, Shibuya M, Sushkova N, Eppihimer MJ, Hawley SP, Rouselle SD, Huibregtse BA, Dawkins KD, Granada JF.

EuroIntervention. 2018 Feb 20;13(14):1670-1679. doi: 10.4244/EIJ-D-17-00332.


Angiographic classification of patterns of restenosis following femoropopliteal artery intervention: A proposed scoring system.

Garcia LA, Rocha-Singh KJ, Krishnan P, Zeller T, Tepe G, Fleming M, Granada JF, Turco MA, Tieché C, Jaff MR.

Catheter Cardiovasc Interv. 2017 Oct 1;90(4):639-646. doi: 10.1002/ccd.27198. Epub 2017 Aug 10.


Comparative Biomechanical Behavior and Healing Profile of a Novel Thinned Wall Ultrahigh Molecular Weight Amorphous Poly-l-Lactic Acid Sirolimus-Eluting Bioresorbable Coronary Scaffold.

Cheng Y, Gasior P, Xia JG, Ramzipoor K, Lee C, Estrada EA, Dokko D, McGregor JC, Conditt GB, McAndrew T, Kaluza GL, Granada JF.

Circ Cardiovasc Interv. 2017 Jul;10(7). pii: e005116. doi: 10.1161/CIRCINTERVENTIONS.117.005116.


Biological effect of microengineered grooved stents on strut healing: a randomised OCT-based comparative study in humans.

Vesga B, Hernandez H, Higuera S, Gasior P, Echeveri D, Delgado JA, Dager A, Arana C, Simonton C, Maehara A, Palmaz J, Granada JF.

Open Heart. 2017 May 22;4(1):e000521. doi: 10.1136/openhrt-2016-000521. eCollection 2017. Erratum in: Open Heart. 2018 Apr 28;5(1):e000521corr1.


Impact of Fluoropolymer-Based Paclitaxel Delivery on Neointimal Proliferation and Vascular Healing: A Comparative Peripheral Drug-Eluting Stent Study in the Familial Hypercholesterolemic Swine Model of Femoral Restenosis.

Gasior P, Cheng Y, Valencia AF, McGregor J, Conditt GB, Kaluza GL, Granada JF.

Circ Cardiovasc Interv. 2017 May;10(5). pii: e004450. doi: 10.1161/CIRCINTERVENTIONS.116.004450.


Novel ultrahigh molecular weight amorphous PLLA bioresorbable coronary scaffold upsized up to 0.8 mm beyond nominal diameter: An OCT and histopathology study in porcine coronary artery model.

Gasior P, Cheng Y, Estrada EA, Jenn McGregor, Ramzipoor K, Lee C, Conditt GB, Rousselle SD, Granada JF, Kaluza GL.

Catheter Cardiovasc Interv. 2018 Feb 15;91(3):378-386. doi: 10.1002/ccd.27108. Epub 2017 May 4.


Transcatheter Mitral Valve Replacement: Insights From Early Clinical Experience and Future Challenges.

Regueiro A, Granada JF, Dagenais F, Rodés-Cabau J.

J Am Coll Cardiol. 2017 May 2;69(17):2175-2192. doi: 10.1016/j.jacc.2017.02.045. Review.


Absorb Bioresorbable Vascular Scaffold Resorption and Imaging Findings: Clarifying Current Misconceptions.

Granada JF.

JACC Cardiovasc Interv. 2017 Apr 10;10(7):746-747. doi: 10.1016/j.jcin.2017.01.039. No abstract available.


Preclinical in vivo long-term evaluation of the novel Mitra-Spacer technology: experimental validation in the ovine model.

Peppas A, Furer A, Wilson J, Yi G, Cheng Y, Van Wygerden K, Seguin C, Shibuya M, Kaluza GL, Granada JF.

EuroIntervention. 2017 Jun 20;13(3):272-279. doi: 10.4244/EIJ-D-16-00609.


Four-year polymer biocompatibility and vascular healing profile of a novel ultrahigh molecular weight amorphous PLLA bioresorbable vascular scaffold: an OCT study in healthy porcine coronary arteries.

Vahl TP, Gasior P, Gongora CA, Ramzipoor K, Lee C, Cheng Y, McGregor J, Shibuya M, Estrada EA, Conditt GB, Kaluza GL, Granada JF.

EuroIntervention. 2016 Dec 20;12(12):1510-1518. doi: 10.4244/EIJ-D-16-00308.


Three-month evaluation of strut healing using a novel optical coherence tomography analytical method following bioresorbable polymer everolimus-eluting stent implantation in humans: the TIMELESS study.

Vesga B, Hernandez H, Moncada M, Gasior P, Higuera S, Dager A, Arana C, Delgado JA, Généreux P, Maehara A, Granada JF.

Coron Artery Dis. 2017 Mar;28(2):126-134. doi: 10.1097/MCA.0000000000000453.


Biological effect on restenosis and vascular healing of encapsulated paclitaxel nanocrystals delivered via coated balloon technology in the familial hypercholesterolaemic swine model of in-stent restenosis.

Cheng Y, Shibuya M, McGregor J, Conditt GB, Yi GH, Kaluza GL, Gray W, Doshi M, Sojitra P, Granada JF.

EuroIntervention. 2016 Oct 20;12(9):1164-1173. doi: 10.4244/EIJV12I9A188.


Comparative Characterization of Biomechanical Behavior and Healing Profile of a Novel Ultra-High-Molecular-Weight Amorphous Poly-l-Lactic Acid Sirolimus-Eluting Bioresorbable Coronary Scaffold.

Cheng Y, Gasior P, Shibuya M, Ramzipoor K, Lee C, Estrada EA, Dokko D, McGregor JC, Conditt GB, Kaluza GL, Granada JF.

Circ Cardiovasc Interv. 2016 Oct;9(10). pii: e004253.


In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models.

Pérez-Medina C, Binderup T, Lobatto ME, Tang J, Calcagno C, Giesen L, Wessel CH, Witjes J, Ishino S, Baxter S, Zhao Y, Ramachandran S, Eldib M, Sánchez-Gaytán BL, Robson PM, Bini J, Granada JF, Fish KM, Stroes ES, Duivenvoorden R, Tsimikas S, Lewis JS, Reiner T, Fuster V, Kjær A, Fisher EA, Fayad ZA, Mulder WJ.

JACC Cardiovasc Imaging. 2016 Aug;9(8):950-61. doi: 10.1016/j.jcmg.2016.01.020. Epub 2016 May 25.


The BVS concept. From the chemical structure to the vascular biology: the bases for a change in interventional cardiology.

Tarantini G, Masiero G, Granada JF, Rapoza RJ.

Minerva Cardioangiol. 2016 Aug;64(4):419-41. Epub 2016 Apr 14. Review.


Significant radiation reduction in interventional fluoroscopy using a novel eye controlled movable region of interest.

Balter S, Simon D, Itkin M, Granada JF, Melman H, Dangas G.

Med Phys. 2016 Mar;43(3):1531-8. doi: 10.1118/1.4941955.


An update on the clinical use of drug-coated balloons in percutaneous coronary interventions.

Cheng Y, Leon MB, Granada JF.

Expert Opin Drug Deliv. 2016 Jun;13(6):859-72. doi: 10.1517/17425247.2016.1154530. Epub 2016 Mar 7. Review.


Biological effect on drug distribution and vascular healing via paclitaxel-coated balloon technology in drug eluting stent restenosis swine model.

Li Y, Tellez A, Rousselle SD, Dillon KN, Garza JA, Barry C, Granada JF.

Catheter Cardiovasc Interv. 2016 Jul;88(1):89-98. doi: 10.1002/ccd.26278. Epub 2015 Nov 28.


Very Late Thrombosis After Bioresorbable Scaffolds: Cause for Concern?

Stone GW, Granada JF.

J Am Coll Cardiol. 2015 Oct 27;66(17):1915-7. doi: 10.1016/j.jacc.2015.08.863. No abstract available.


In vivo delivery and long-term tissue retention of nano-encapsulated sirolimus using a novel porous balloon angioplasty system.

Granada JF, Tellez A, Baumbach WR, Bingham B, Keng YF, Wessler J, Conditt G, McGregor J, Stone G, Kaluza GL, Leon MB.

EuroIntervention. 2016 Aug 20;12(6):740-7. doi: 10.4244/EIJY15M10_01.


Stenting and Adjunctive Delivery of Paclitaxel Via Balloon Coating Versus Durable Polymeric Matrix for De Novo Coronary Lesions: Clinical and Angiographic Results from the Prospective Randomized Trial.

Żurakowski A, Buszman PP, Milewski KP, Janas A, Gorycki B, Kondys M, Gąsior P, Michalak M, Boxberger M, Peppas A, Granada JF, Buszman PE.

J Interv Cardiol. 2015 Aug;28(4):348-57. doi: 10.1111/joic.12210.


Impact of Paclitaxel Dose on Tissue Pharmacokinetics and Vascular Healing: A Comparative Drug-Coated Balloon Study in the Familial Hypercholesterolemic Swine Model of Superficial Femoral In-Stent Restenosis.

Gongora CA, Shibuya M, Wessler JD, McGregor J, Tellez A, Cheng Y, Conditt GB, Kaluza GL, Granada JF.

JACC Cardiovasc Interv. 2015 Jul;8(8):1115-1123. doi: 10.1016/j.jcin.2015.03.020. Epub 2015 Jun 24.


Drug-coated balloon treatment for lower extremity vascular disease intervention: an international positioning document.

Cortese B, Granada JF, Scheller B, Schneider PA, Tepe G, Scheinert D, Garcia L, Stabile E, Alfonso F, Ansel G, Zeller T.

Eur Heart J. 2016 Apr 7;37(14):1096-103. doi: 10.1093/eurheartj/ehv204. Epub 2015 May 24. Review. No abstract available.


Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study.

Suter MJ, Kashiwagi M, Gallagher KA, Nadkarni SK, Asanani N, Tanaka A, Conditt GB, Tellez A, Milewski K, Kaluza GL, Granada JF, Bouma BE, Tearney GJ.

Int J Cardiovasc Imaging. 2015 Aug;31(6):1097-106. doi: 10.1007/s10554-015-0668-0. Epub 2015 Apr 29.


Early feasibility evaluation of thoracoscopically assisted transcatheter ventricular reconstruction in an experimental model of ischaemic heart failure with left anteroapical aneurysm.

Cheng Y, Yi GH, Annest LS, Van Bladel K, Brown R, Wechsler A, Shibuya M, Conditt GB, Peppas A, Kaluza GL, Granada JF.

EuroIntervention. 2015 Apr;10(12):1480-7. doi: 10.4244/EIJV10I12A259.

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