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Items: 49

1.

CD38, a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies.

Morandi F, Airoldi I, Marimpietri D, Bracci C, Faini AC, Gramignoli R.

Cells. 2019 Nov 27;8(12). pii: E1527. doi: 10.3390/cells8121527. Review.

2.

Assessment of animal experimental models of toxic liver injury in the context of their potential application as preclinical models for cell therapy.

Czekaj P, Król M, Limanówka Ł, Michalik M, Lorek K, Gramignoli R.

Eur J Pharmacol. 2019 Oct 15;861:172597. doi: 10.1016/j.ejphar.2019.172597. Epub 2019 Aug 10.

PMID:
31408648
3.

Increased immunomodulatory capacity of human amniotic cells after activation by pro-inflammatory chemokines.

Kolanko E, Kopaczka K, Koryciak-Komarska H, Czech E, Szmytkowska P, Gramignoli R, Czekaj P.

Eur J Pharmacol. 2019 Sep 15;859:172545. doi: 10.1016/j.ejphar.2019.172545. Epub 2019 Jul 15.

PMID:
31319066
4.

Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived Hepatocytes.

Zabulica M, Srinivasan RC, Vosough M, Hammarstedt C, Wu T, Gramignoli R, Ellis E, Kannisto K, Collin de l'Hortet A, Takeishi K, Soto-Gutierrez A, Strom SC.

Stem Cells Dev. 2019 Jul 15;28(14):907-919. doi: 10.1089/scd.2019.0064.

5.

Role of Toll-Like Receptors in Actuating Stem/Progenitor Cell Repair Mechanisms: Different Functions in Different Cells.

Sallustio F, Curci C, Stasi A, De Palma G, Divella C, Gramignoli R, Castellano G, Gallone A, Gesualdo L.

Stem Cells Int. 2019 Apr 4;2019:6795845. doi: 10.1155/2019/6795845. eCollection 2019. Review.

6.

Prenatal liver stromal cells: Favorable feeder cells for long-term culture of hepatic progenitor cells.

Feizi Z, Zahmatkesh E, Farzaneh Z, Piryaei A, Gramignoli R, Nussler AK, Baharvand H, Vosough M.

J Cell Biochem. 2019 Oct;120(10):16624-16633. doi: 10.1002/jcb.28921. Epub 2019 May 12.

PMID:
31081256
7.

Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts.

Vosough M, Ravaioli F, Zabulica M, Capri M, Garagnani P, Franceschi C, Piccand J, Kraus MR, Kannisto K, Gramignoli R, Strom SC.

PLoS One. 2019 Apr 25;14(4):e0215490. doi: 10.1371/journal.pone.0215490. eCollection 2019.

8.

A liver-humanized mouse model of carbamoyl phosphate synthetase 1-deficiency.

Srinivasan RC, Zabulica M, Hammarstedt C, Wu T, Gramignoli R, Kannisto K, Ellis E, Karadagi A, Fingerhut R, Allegri G, Rüfenacht V, Thöny B, Häberle J, Nuoffer JM, Strom SC.

J Inherit Metab Dis. 2019 Nov;42(6):1054-1063. doi: 10.1002/jimd.12067. Epub 2019 Apr 2.

9.

Editorial: Tissue Repair and Regenerative Mechanisms by Stem/Progenitor Cells and Their Secretome.

Gramignoli R, Sallustio F, Widera D, Raschzok N.

Front Med (Lausanne). 2019 Jan 31;6:11. doi: 10.3389/fmed.2019.00011. eCollection 2019. No abstract available.

10.

Ectonucleotidase Expression on Human Amnion Epithelial Cells: Adenosinergic Pathways and Dichotomic Effects on Immune Effector Cell Populations.

Morandi F, Horenstein AL, Quarona V, Faini AC, Castella B, Srinivasan RC, Strom SC, Malavasi F, Gramignoli R.

J Immunol. 2019 Feb 1;202(3):724-735. doi: 10.4049/jimmunol.1800432. Epub 2018 Dec 26.

PMID:
30587530
11.

Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma.

Augello G, Emma MR, Cusimano A, Azzolina A, Mongiovì S, Puleio R, Cassata G, Gulino A, Belmonte B, Gramignoli R, Strom SC, McCubrey JA, Montalto G, Cervello M.

Int J Cancer. 2019 May 15;144(10):2613-2624. doi: 10.1002/ijc.31963. Epub 2018 Dec 24.

PMID:
30488605
12.

Evaluation of different routes of administration and biodistribution of human amnion epithelial cells in mice.

Srinivasan RC, Kannisto K, Strom SC, Gramignoli R.

Cytotherapy. 2019 Jan;21(1):113-124. doi: 10.1016/j.jcyt.2018.10.007. Epub 2018 Nov 5.

PMID:
30409699
13.

Complications and Outcomes of Endoscopic Treatment in a Cohort of Patients With Biliary Stenosis After Orthotopic Liver Transplant: A Retrospective Observational Study.

Bortolasi L, Violi P, Carraro A, Montin U, Cerofolini A, Munari A, Eccher A, Gramignoli R, Bovo C, Tedeschi U.

Exp Clin Transplant. 2019 Aug;17(4):513-521. doi: 10.6002/ect.2018.0167. Epub 2018 Oct 19.

14.

Molecular Aging of Human Liver: An Epigenetic/Transcriptomic Signature.

Bacalini MG, Franceschi C, Gentilini D, Ravaioli F, Zhou X, Remondini D, Pirazzini C, Giuliani C, Marasco E, Gensous N, Di Blasio AM, Ellis E, Gramignoli R, Castellani G, Capri M, Strom S, Nardini C, Cescon M, Grazi GL, Garagnani P.

J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):1-8. doi: 10.1093/gerona/gly048.

PMID:
29554203
15.

Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation.

Cusimano A, Balasus D, Azzolina A, Augello G, Emma MR, Di Sano C, Gramignoli R, Strom SC, McCubrey JA, Montalto G, Cervello M.

Int J Oncol. 2017 Aug;51(2):533-544. doi: 10.3892/ijo.2017.4049. Epub 2017 Jun 21.

PMID:
28656311
16.

Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression.

Karadagi A, Johansson H, Zemack H, Salipalli S, Mörk LM, Kannisto K, Jorns C, Gramignoli R, Strom S, Stokkeland K, Ericzon BG, Jonigk D, Janciauskiene S, Nowak G, Ellis ECS.

PLoS One. 2017 May 9;12(5):e0177279. doi: 10.1371/journal.pone.0177279. eCollection 2017.

17.

Differentiation of amniotic epithelial cells into various liver cell types and potential therapeutic applications.

Fanti M, Gramignoli R, Serra M, Cadoni E, Strom SC, Marongiu F.

Placenta. 2017 Nov;59:139-145. doi: 10.1016/j.placenta.2017.03.020. Epub 2017 Mar 30. Review.

PMID:
28411944
18.

Host conditioning and rejection monitoring in hepatocyte transplantation in humans.

Soltys KA, Setoyama K, Tafaleng EN, Soto Gutiérrez A, Fong J, Fukumitsu K, Nishikawa T, Nagaya M, Sada R, Haberman K, Gramignoli R, Dorko K, Tahan V, Dreyzin A, Baskin K, Crowley JJ, Quader MA, Deutsch M, Ashokkumar C, Shneider BL, Squires RH, Ranganathan S, Reyes-Mugica M, Dobrowolski SF, Mazariegos G, Elango R, Stolz DB, Strom SC, Vockley G, Roy-Chowdhury J, Cascalho M, Guha C, Sindhi R, Platt JL, Fox IJ.

J Hepatol. 2017 May;66(5):987-1000. doi: 10.1016/j.jhep.2016.12.017. Epub 2016 Dec 24.

19.

Human amnion epithelial cells expressing HLA-G as novel cell-based treatment for liver disease.

Strom SC, Gramignoli R.

Hum Immunol. 2016 Sep;77(9):734-9. doi: 10.1016/j.humimm.2016.07.002. Epub 2016 Jul 27. Review.

PMID:
27476049
20.

Isolation of Human Amnion Epithelial Cells According to Current Good Manufacturing Procedures.

Gramignoli R, Srinivasan RC, Kannisto K, Strom SC.

Curr Protoc Stem Cell Biol. 2016 May 12;37:1E.10.1-1E.10.13. doi: 10.1002/cpsc.2.

PMID:
27171794
21.

Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny.

Giebel NL, Shadley JD, McCarver DG, Dorko K, Gramignoli R, Strom SC, Yan K, Simpson PM, Hines RN.

Drug Metab Dispos. 2016 Jul;44(7):1027-37. doi: 10.1124/dmd.116.069344. Epub 2016 Feb 26.

22.

The Use of Induced Pluripotent Stem Cells for the Study and Treatment of Liver Diseases.

Hansel MC, Davila JC, Vosough M, Gramignoli R, Skvorak KJ, Dorko K, Marongiu F, Blake W, Strom SC.

Curr Protoc Toxicol. 2016 Feb 1;67:14.13.1-14.13.27. doi: 10.1002/0471140856.tx1413s67. Review.

23.

De Novo Donor-Specific HLA Antibody Formation in Two Patients With Crigler-Najjar Syndrome Type I Following Human Hepatocyte Transplantation With Partial Hepatectomy Preconditioning.

Jorns C, Nowak G, Nemeth A, Zemack H, Mörk LM, Johansson H, Gramignoli R, Watanabe M, Karadagi A, Alheim M, Hauzenberger D, van Dijk R, Bosma PJ, Ebbesen F, Szakos A, Fischler B, Strom S, Ellis E, Ericzon BG.

Am J Transplant. 2016 Mar;16(3):1021-30. doi: 10.1111/ajt.13487. Epub 2015 Nov 2.

24.

Clinical hepatocyte transplantation: practical limits and possible solutions.

Gramignoli R, Vosough M, Kannisto K, Srinivasan RC, Strom SC.

Eur Surg Res. 2015;54(3-4):162-77. doi: 10.1159/000369552. Epub 2015 Jan 23. Review.

PMID:
25633583
25.

The history and use of human hepatocytes for the treatment of liver diseases: the first 100 patients.

Hansel MC, Gramignoli R, Skvorak KJ, Dorko K, Marongiu F, Blake W, Davila J, Strom SC.

Curr Protoc Toxicol. 2014 Nov 6;62:14.12.1-23. doi: 10.1002/0471140856.tx1412s62.

26.

Strategies for short-term storage of hepatocytes for repeated clinical infusions.

Jorns C, Gramignoli R, Saliem M, Zemack H, Mörk LM, Isaksson B, Nowak G, Ericzon BG, Strom S, Ellis E.

Cell Transplant. 2014;23(8):1009-18. doi: 10.3727/096368913X667484.

PMID:
25199147
27.

Rapid and sensitive assessment of human hepatocyte functions.

Gramignoli R, Tahan V, Dorko K, Venkataramanan R, Fox IJ, Ellis EC, Vosough M, Strom SC.

Cell Transplant. 2014;23(12):1545-56. doi: 10.3727/096368914X680064. Epub 2014 Apr 4.

PMID:
24702711
28.

Translation of amnion stem cells to the clinic.

Strom SC, Skvorak K, Gramignoli R, Marongiu F, Miki T.

Stem Cells Dev. 2013 Dec;22 Suppl 1:96-102. doi: 10.1089/scd.2013.0391.

PMID:
24304085
29.

Potential barriers to human hepatocyte transplantation in MUP-uPAtg(⁺/⁺)Rag2⁻/⁻γC⁻/⁻ mice.

Komori J, DeWard AD, Gramignoli R, Strom SC, Fontes P, Lagasse E.

Cell Transplant. 2014;23(12):1537-44. doi: 10.3727/096368913X672046. Epub 2013 Aug 30.

PMID:
23998208
30.

Ritonavir and efavirenz significantly alter the metabolism of erlotinib--an observation in primary cultures of human hepatocytes that is relevant to HIV patients with cancer.

Pillai VC, Venkataramanan R, Parise RA, Christner SM, Gramignoli R, Strom SC, Rudek MA, Beumer JH.

Drug Metab Dispos. 2013 Oct;41(10):1843-51. doi: 10.1124/dmd.113.052100. Epub 2013 Aug 2.

31.

Hypothermic storage of human hepatocytes for transplantation.

Gramignoli R, Dorko K, Tahan V, Skvorak KJ, Ellis E, Jorns C, Ericzon BG, Fox IJ, Strom SC.

Cell Transplant. 2014;23(9):1143-51. doi: 10.3727/096368913X668627.

PMID:
23768881
32.

New potential cell source for hepatocyte transplantation: discarded livers from metabolic disease liver transplants.

Gramignoli R, Tahan V, Dorko K, Skvorak KJ, Hansel MC, Zhao W, Venkataramanan R, Ellis EC, Jorns C, Ericzon BG, Rosenborg S, Kuiper R, Soltys KA, Mazariegos GV, Fox IJ, Wilson EM, Grompe M, Strom SC.

Stem Cell Res. 2013 Jul;11(1):563-73. doi: 10.1016/j.scr.2013.03.002. Epub 2013 Mar 27.

33.

Improved amino acid, bioenergetic metabolite and neurotransmitter profiles following human amnion epithelial cell transplant in intermediate maple syrup urine disease mice.

Skvorak KJ, Dorko K, Marongiu F, Tahan V, Hansel MC, Gramignoli R, Arning E, Bottiglieri T, Gibson KM, Strom SC.

Mol Genet Metab. 2013 Jun;109(2):132-8. doi: 10.1016/j.ymgme.2013.02.011. Epub 2013 Feb 26.

PMID:
23566440
34.

Increased reprogramming of human fetal hepatocytes compared with adult hepatocytes in feeder-free conditions.

Hansel MC, Gramignoli R, Blake W, Davila J, Skvorak K, Dorko K, Tahan V, Lee BR, Tafaleng E, Guzman-Lepe J, Soto-Gutierrez A, Fox IJ, Strom SC.

Cell Transplant. 2014 Jan;23(1):27-38. doi: 10.3727/096368912X662453. Epub 2013 Feb 4.

35.

Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORα and RORγ and its potential relevance to human liver diseases.

Ou Z, Shi X, Gilroy RK, Kirisci L, Romkes M, Lynch C, Wang H, Xu M, Jiang M, Ren S, Gramignoli R, Strom SC, Huang M, Xie W.

Mol Endocrinol. 2013 Jan;27(1):106-15. doi: 10.1210/me.2012-1145. Epub 2012 Dec 4.

36.

Placental stem cell correction of murine intermediate maple syrup urine disease.

Skvorak KJ, Dorko K, Marongiu F, Tahan V, Hansel MC, Gramignoli R, Gibson KM, Strom SC.

Hepatology. 2013 Mar;57(3):1017-23. doi: 10.1002/hep.26150. Epub 2013 Feb 15.

37.

Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes.

Sharma S, Ellis EC, Gramignoli R, Dorko K, Tahan V, Hansel M, Mattison DR, Caritis SN, Hines RN, Venkataramanan R, Strom SC.

Drug Metab Dispos. 2013 Feb;41(2):296-304. doi: 10.1124/dmd.112.044891. Epub 2012 Nov 5.

38.

ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.

Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O'Doherty RM, Stewart AF, Vasavada RC, Garcia-Ocaña A, Scott DK.

Diabetes. 2012 Aug;61(8):2004-15. doi: 10.2337/db11-0802. Epub 2012 May 14.

39.

Development and application of purified tissue dissociation enzyme mixtures for human hepatocyte isolation.

Gramignoli R, Green ML, Tahan V, Dorko K, Skvorak KJ, Marongiu F, Zao W, Venkataramanan R, Ellis EC, Geller D, Breite AG, Dwulet FE, McCarthy RC, Strom SC.

Cell Transplant. 2012;21(6):1245-60. doi: 10.3727/096368911X600939. Epub 2011 Nov 11.

PMID:
22080793
40.

FoxO6 integrates insulin signaling with gluconeogenesis in the liver.

Kim DH, Perdomo G, Zhang T, Slusher S, Lee S, Phillips BE, Fan Y, Giannoukakis N, Gramignoli R, Strom S, Ringquist S, Dong HH.

Diabetes. 2011 Nov;60(11):2763-74. doi: 10.2337/db11-0548. Epub 2011 Sep 22.

41.

A whole-organ regenerative medicine approach for liver replacement.

Soto-Gutierrez A, Zhang L, Medberry C, Fukumitsu K, Faulk D, Jiang H, Reing J, Gramignoli R, Komori J, Ross M, Nagaya M, Lagasse E, Stolz D, Strom SC, Fox IJ, Badylak SF.

Tissue Eng Part C Methods. 2011 Jun;17(6):677-86. doi: 10.1089/ten.tec.2010.0698. Epub 2011 Apr 20.

42.

Hepatic differentiation of amniotic epithelial cells.

Marongiu F, Gramignoli R, Dorko K, Miki T, Ranade AR, Paola Serra M, Doratiotto S, Sini M, Sharma S, Mitamura K, Sellaro TL, Tahan V, Skvorak KJ, Ellis EC, Badylak SF, Davila JC, Hines R, Laconi E, Strom SC.

Hepatology. 2011 May;53(5):1719-29. doi: 10.1002/hep.24255.

43.

MicroRNA hsa-miR-613 targets the human LXRα gene and mediates a feedback loop of LXRα autoregulation.

Ou Z, Wada T, Gramignoli R, Li S, Strom SC, Huang M, Xie W.

Mol Endocrinol. 2011 Apr;25(4):584-96. doi: 10.1210/me.2010-0360. Epub 2011 Feb 10.

44.

Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats.

Tahan G, Gramignoli R, Marongiu F, Aktolga S, Cetinkaya A, Tahan V, Dorko K.

Dig Dis Sci. 2011 Mar;56(3):715-20. doi: 10.1007/s10620-010-1364-5. Epub 2010 Jul 30.

PMID:
20676767
45.

FoxO1 links hepatic insulin action to endoplasmic reticulum stress.

Kamagate A, Kim DH, Zhang T, Slusher S, Gramignoli R, Strom SC, Bertera S, Ringquist S, Dong HH.

Endocrinology. 2010 Aug;151(8):3521-35. doi: 10.1210/en.2009-1306. Epub 2010 May 25.

46.

Isolation of amniotic mesenchymal stem cells.

Marongiu F, Gramignoli R, Sun Q, Tahan V, Miki T, Dorko K, Ellis E, Strom SC.

Curr Protoc Stem Cell Biol. 2010 Mar;Chapter 1:Unit 1E.5. doi: 10.1002/9780470151808.sc01e05s12.

PMID:
20200854
47.

Production of hepatocyte-like cells from human amnion.

Miki T, Marongiu F, Ellis EC, Dorko K, Mitamura K, Ranade A, Gramignoli R, Davila J, Strom SC.

Methods Mol Biol. 2009;481:155-68. doi: 10.1007/978-1-59745-201-4_13. Review.

PMID:
19096803
48.

Animal model for liver cell banking from non-heart beating donors after prolonged ischaemia time.

Porretti L, Gatti S, Gramignoli R, Colombo F, Lopa R, Cattaneo A, Scalamogna M, Colombo G, Rossi G, Bonino F, Rebulla P, Prati D.

Dig Liver Dis. 2006 Dec;38(12):905-11. Epub 2006 Aug 21.

PMID:
16920045
49.

Clinical and histological characterization of liver disease in patients with transfusion-dependent beta-thalassemia. A multicenter study of 117 cases.

Prati D, Maggioni M, Milani S, Cerino M, Cianciulli P, Coggi G, Forni GL, Magnano C, Meo A, Gramignoli R, Rebulla P, Fiorelli G, Cappellini MD; Cooleycare Cooperative Group.

Haematologica. 2004 Oct;89(10):1179-86.

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