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Items: 24


Establishment of an induced memory response in Pseudomonas aeruginosa during infection of a eukaryotic host.

Kordes A, Grahl N, Koska M, Preusse M, Arce-Rodriguez A, Abraham WR, Kaever V, Häussler S.

ISME J. 2019 Aug;13(8):2018-2030. doi: 10.1038/s41396-019-0412-1. Epub 2019 Apr 5.


Importance of flagella in acute and chronic Pseudomonas aeruginosa infections.

Lorenz A, Preuße M, Bruchmann S, Pawar V, Grahl N, Pils MC, Nolan LM, Filloux A, Weiss S, Häussler S.

Environ Microbiol. 2019 Mar;21(3):883-897. doi: 10.1111/1462-2920.14468. Epub 2018 Dec 3.


Refining the Application of Microbial Lipids as Tracers of Staphylococcus aureus Growth Rates in Cystic Fibrosis Sputum.

Neubauer C, Kasi AS, Grahl N, Sessions AL, Kopf SH, Kato R, Hogan DA, Newman DK.

J Bacteriol. 2018 Nov 26;200(24). pii: e00365-18. doi: 10.1128/JB.00365-18. Print 2018 Dec 15.


Profiling of Bacterial and Fungal Microbial Communities in Cystic Fibrosis Sputum Using RNA.

Grahl N, Dolben EL, Filkins LM, Crocker AW, Willger SD, Morrison HG, Sogin ML, Ashare A, Gifford AH, Jacobs NJ, Schwartzman JD, Hogan DA.

mSphere. 2018 Aug 8;3(4). pii: e00292-18. doi: 10.1128/mSphere.00292-18.


Use of RNA-Protein Complexes for Genome Editing in Non-albicans Candida Species.

Grahl N, Demers EG, Crocker AW, Hogan DA.

mSphere. 2017 Jun 21;2(3). pii: e00218-17. doi: 10.1128/mSphere.00218-17. eCollection 2017 May-Jun.


Pseudomonas aeruginosa Alginate Overproduction Promotes Coexistence with Staphylococcus aureus in a Model of Cystic Fibrosis Respiratory Infection.

Limoli DH, Whitfield GB, Kitao T, Ivey ML, Davis MR Jr, Grahl N, Hogan DA, Rahme LG, Howell PL, O'Toole GA, Goldberg JB.

MBio. 2017 Mar 21;8(2). pii: e00186-17. doi: 10.1128/mBio.00186-17.


Global Role of Cyclic AMP Signaling in pH-Dependent Responses in Candida albicans.

Hollomon JM, Grahl N, Willger SD, Koeppen K, Hogan DA.

mSphere. 2016 Nov 30;1(6). pii: e00283-16. eCollection 2016 Nov-Dec.


Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues.

Xie JL, Grahl N, Sless T, Leach MD, Kim SH, Hogan DA, Robbins N, Cowen LE.

PLoS Genet. 2016 Oct 27;12(10):e1006405. doi: 10.1371/journal.pgen.1006405. eCollection 2016 Oct.


Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways.

Grahl N, Demers EG, Lindsay AK, Harty CE, Willger SD, Piispanen AE, Hogan DA.

PLoS Pathog. 2015 Aug 28;11(8):e1005133. doi: 10.1371/journal.ppat.1005133. eCollection 2015 Aug.


Analysis of Candida albicans mutants defective in the Cdk8 module of mediator reveal links between metabolism and biofilm formation.

Lindsay AK, Morales DK, Liu Z, Grahl N, Zhang A, Willger SD, Myers LC, Hogan DA.

PLoS Genet. 2014 Oct 2;10(10):e1004567. doi: 10.1371/journal.pgen.1004567. eCollection 2014 Oct.


Two C4-sterol methyl oxidases (Erg25) catalyse ergosterol intermediate demethylation and impact environmental stress adaptation in Aspergillus fumigatus.

Blosser SJ, Merriman B, Grahl N, Chung D, Cramer RA.

Microbiology. 2014 Nov;160(Pt 11):2492-506. doi: 10.1099/mic.0.080440-0. Epub 2014 Aug 8.


Regulated proteolysis of Candida albicans Ras1 is involved in morphogenesis and quorum sensing regulation.

Piispanen AE, Grahl N, Hollomon JM, Hogan DA.

Mol Microbiol. 2013 Jul;89(1):166-78. doi: 10.1111/mmi.12268. Epub 2013 Jun 10.


Control of Candida albicans metabolism and biofilm formation by Pseudomonas aeruginosa phenazines.

Morales DK, Grahl N, Okegbe C, Dietrich LE, Jacobs NJ, Hogan DA.

MBio. 2013 Jan 29;4(1):e00526-12. doi: 10.1128/mBio.00526-12.


Hypoxia and fungal pathogenesis: to air or not to air?

Grahl N, Shepardson KM, Chung D, Cramer RA.

Eukaryot Cell. 2012 May;11(5):560-70. doi: 10.1128/EC.00031-12. Epub 2012 Mar 23. Review.


Aspergillus fumigatus mitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis.

Grahl N, Dinamarco TM, Willger SD, Goldman GH, Cramer RA.

Mol Microbiol. 2012 Apr;84(2):383-99. doi: 10.1111/j.1365-2958.2012.08034.x. Epub 2012 Mar 23.


SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus.

Blatzer M, Barker BM, Willger SD, Beckmann N, Blosser SJ, Cornish EJ, Mazurie A, Grahl N, Haas H, Cramer RA.

PLoS Genet. 2011 Dec;7(12):e1002374. doi: 10.1371/journal.pgen.1002374. Epub 2011 Dec 1.


HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.

Feng X, Krishnan K, Richie DL, Aimanianda V, Hartl L, Grahl N, Powers-Fletcher MV, Zhang M, Fuller KK, Nierman WC, Lu LJ, Latgé JP, Woollett L, Newman SL, Cramer RA Jr, Rhodes JC, Askew DS.

PLoS Pathog. 2011 Oct;7(10):e1002330. doi: 10.1371/journal.ppat.1002330. Epub 2011 Oct 20.


In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis.

Grahl N, Puttikamonkul S, Macdonald JM, Gamcsik MP, Ngo LY, Hohl TM, Cramer RA.

PLoS Pathog. 2011 Jul;7(7):e1002145. doi: 10.1371/journal.ppat.1002145. Epub 2011 Jul 21.


The small GTPase RacA mediates intracellular reactive oxygen species production, polarized growth, and virulence in the human fungal pathogen Aspergillus fumigatus.

Li H, Barker BM, Grahl N, Puttikamonkul S, Bell JD, Craven KD, Cramer RA Jr.

Eukaryot Cell. 2011 Feb;10(2):174-86. doi: 10.1128/EC.00288-10. Epub 2010 Dec 23.


Trehalose 6-phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus.

Puttikamonkul S, Willger SD, Grahl N, Perfect JR, Movahed N, Bothner B, Park S, Paderu P, Perlin DS, Cramer RA Jr.

Mol Microbiol. 2010 Aug;77(4):891-911. doi: 10.1111/j.1365-2958.2010.07254.x. Epub 2010 Jun 9.


TmpL, a transmembrane protein required for intracellular redox homeostasis and virulence in a plant and an animal fungal pathogen.

Kim KH, Willger SD, Park SW, Puttikamonkul S, Grahl N, Cho Y, Mukhopadhyay B, Cramer RA Jr, Lawrence CB.

PLoS Pathog. 2009 Nov;5(11):e1000653. doi: 10.1371/journal.ppat.1000653. Epub 2009 Nov 6.


Regulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?

Grahl N, Cramer RA Jr.

Med Mycol. 2010 Feb;48(1):1-15. doi: 10.3109/13693780902947342. Review.


Aspergillus fumigatus metabolism: clues to mechanisms of in vivo fungal growth and virulence.

Willger SD, Grahl N, Cramer RA Jr.

Med Mycol. 2009;47 Suppl 1:S72-9. doi: 10.1080/13693780802455313. Epub 2009 Feb 27. Review.


A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus.

Willger SD, Puttikamonkul S, Kim KH, Burritt JB, Grahl N, Metzler LJ, Barbuch R, Bard M, Lawrence CB, Cramer RA Jr.

PLoS Pathog. 2008 Nov;4(11):e1000200. doi: 10.1371/journal.ppat.1000200. Epub 2008 Nov 7.

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