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Items: 1 to 50 of 64

1.

Connexins in cancer: bridging the gap to the clinic.

Aasen T, Leithe E, Graham SV, Kameritsch P, Mayán MD, Mesnil M, Pogoda K, Tabernero A.

Oncogene. 2019 Jun;38(23):4429-4451. doi: 10.1038/s41388-019-0741-6. Epub 2019 Feb 27.

PMID:
30814684
2.

Host Vesicle Fusion Protein VAPB Contributes to the Nuclear Egress Stage of Herpes Simplex Virus Type-1 (HSV-1) Replication.

Saiz-Ros N, Czapiewski R, Epifano I, Stevenson A, Swanson SK, Dixon CR, Zamora DB, McElwee M, Vijayakrishnan S, Richardson CA, Dong L, Kelly DA, Pytowski L, Goldberg MW, Florens L, Graham SV, Schirmer EC.

Cells. 2019 Feb 3;8(2). pii: E120. doi: 10.3390/cells8020120.

3.

Increased risk of HPV-associated genital cancers in men and women as a consequence of pre-invasive disease.

Pan J, Kavanagh K, Cuschieri K, Pollock KG, Gilbert DC, Millan D, Bell S, Graham SV, Williams ARW, Cruickshank ME, Palmer T, Wakeham K.

Int J Cancer. 2019 Jul 15;145(2):427-434. doi: 10.1002/ijc.32126. Epub 2019 Mar 4.

PMID:
30650180
4.

Risk stratification of cervical disease using detection of human papillomavirus (HPV) E4 protein and cellular MCM protein in clinical liquid based cytology samples.

Stevenson A, Kavanagh K, Pan J, Stevenson L, Griffin H, Doorbar J, Scott E, Deeny M, Cuschieri K, Graham SV.

J Clin Virol. 2018 Nov;108:19-25. doi: 10.1016/j.jcv.2018.08.011. Epub 2018 Aug 31.

5.

Connexins and Pannexins: Important Players in Tumorigenesis, Metastasis and Potential Therapeutics.

Graham SV, Jiang JX, Mesnil M.

Int J Mol Sci. 2018 Jun 1;19(6). pii: E1645. doi: 10.3390/ijms19061645. Review.

6.

RNA-Seq Analysis of Differentiated Keratinocytes Reveals a Massive Response to Late Events during Human Papillomavirus 16 Infection, Including Loss of Epithelial Barrier Function.

Klymenko T, Gu Q, Herbert I, Stevenson A, Iliev V, Watkins G, Pollock C, Bhatia R, Cuschieri K, Herzyk P, Gatherer D, Graham SV.

J Virol. 2017 Nov 30;91(24). pii: e01001-17. doi: 10.1128/JVI.01001-17. Print 2017 Dec 15.

7.

Keratinocyte Differentiation-Dependent Human Papillomavirus Gene Regulation.

Graham SV.

Viruses. 2017 Aug 30;9(9). pii: E245. doi: 10.3390/v9090245. Review.

8.

The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review.

Graham SV.

Clin Sci (Lond). 2017 Aug 10;131(17):2201-2221. doi: 10.1042/CS20160786. Print 2017 Sep 1. Review.

PMID:
28798073
9.

Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding.

Smith RWP, Anderson RC, Larralde O, Smith JWS, Gorgoni B, Richardson WA, Malik P, Graham SV, Gray NK.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6310-6315. doi: 10.1073/pnas.1610417114. Epub 2017 May 30.

10.

Control of human papillomavirus gene expression by alternative splicing.

Graham SV, Faizo AAA.

Virus Res. 2017 Mar 2;231:83-95. doi: 10.1016/j.virusres.2016.11.016. Epub 2016 Nov 17. Review.

11.

HPV status and favourable outcome in vulvar squamous cancer.

Wakeham K, Kavanagh K, Cuschieri K, Millan D, Pollock KG, Bell S, Burton K, Reed NS, Graham SV.

Int J Cancer. 2017 Mar 1;140(5):1134-1146. doi: 10.1002/ijc.30523.

12.

Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA Processing.

Graham SV.

J Virol. 2016 Sep 12;90(19):8384-8. doi: 10.1128/JVI.00502-16. Print 2016 Oct 1. Review.

13.

Human Papillomavirus E2 Regulates SRSF3 (SRp20) To Promote Capsid Protein Expression in Infected Differentiated Keratinocytes.

Klymenko T, Hernandez-Lopez H, MacDonald AI, Bodily JM, Graham SV.

J Virol. 2016 Apr 29;90(10):5047-58. doi: 10.1128/JVI.03073-15. Print 2016 May 15.

14.

HPV16 E6 Controls the Gap Junction Protein Cx43 in Cervical Tumour Cells.

Sun P, Dong L, MacDonald AI, Akbari S, Edward M, Hodgins MB, Johnstone SR, Graham SV.

Viruses. 2015 Oct 5;7(10):5243-56. doi: 10.3390/v7102871.

15.

Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35).

McFarlane M, MacDonald AI, Stevenson A, Graham SV.

J Virol. 2015 May;89(10):5276-87. doi: 10.1128/JVI.03434-14. Epub 2015 Feb 25.

16.

Assessing the detection of human papillomavirus late mRNA in liquid base cytology samples for risk stratification of cervical disease.

Chambers G, Millan D, Cuschieri K, Cubie HA, Graham SV.

J Med Virol. 2014 Apr;86(4):627-33. doi: 10.1002/jmv.23793. Epub 2013 Oct 19.

17.

Gaps in detailed knowledge of human papillomavirus (HPV) and the HPV vaccine among medical students in Scotland.

McCusker SM, Macqueen I, Lough G, Macdonald AI, Campbell C, Graham SV.

BMC Public Health. 2013 Mar 22;13:264. doi: 10.1186/1471-2458-13-264.

18.

Oncolytic herpes viruses, chemotherapeutics, and other cancer drugs.

Braidwood L, Graham SV, Graham A, Conner J.

Oncolytic Virother. 2013 Dec 4;2:57-74. doi: 10.2147/OV.S52601. eCollection 2013. Review.

19.

Human papillomavirus gene expression is controlled by host cell splicing factors.

Klymenko T, Graham SV.

Biochem Soc Trans. 2012 Aug;40(4):773-7. doi: 10.1042/BST20120079. Review.

PMID:
22817732
20.

Alternative splicing in human tumour viruses: a therapeutic target?

Hernandez-Lopez HR, Graham SV.

Biochem J. 2012 Jul 15;445(2):145-56. doi: 10.1042/BJ20120413. Review.

PMID:
22738337
21.

A functional interaction between the MAGUK protein hDlg and the gap junction protein connexin 43 in cervical tumour cells.

Macdonald AI, Sun P, Hernandez-Lopez H, Aasen T, Hodgins MB, Edward M, Roberts S, Massimi P, Thomas M, Banks L, Graham SV.

Biochem J. 2012 Aug 15;446(1):9-21. doi: 10.1042/BJ20111144.

PMID:
22657348
22.

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways.

Malik P, Tabarraei A, Kehlenbach RH, Korfali N, Iwasawa R, Graham SV, Schirmer EC.

J Biol Chem. 2012 Apr 6;287(15):12277-92. doi: 10.1074/jbc.M111.331777. Epub 2012 Feb 14.

23.

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.

Burgess HM, Richardson WA, Anderson RC, Salaun C, Graham SV, Gray NK.

J Cell Sci. 2011 Oct 1;124(Pt 19):3344-55. doi: 10.1242/jcs.087692.

24.

Human papillomavirus: gene expression, regulation and prospects for novel diagnostic methods and antiviral therapies.

Graham SV.

Future Microbiol. 2010 Oct;5(10):1493-506. doi: 10.2217/fmb.10.107. Review.

25.

HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells.

Campo MS, Graham SV, Cortese MS, Ashrafi GH, Araibi EH, Dornan ES, Miners K, Nunes C, Man S.

Virology. 2010 Nov 10;407(1):137-42. doi: 10.1016/j.virol.2010.07.044.

26.

Human papillomavirus regulation of SR proteins.

McFarlane M, Graham SV.

Biochem Soc Trans. 2010 Aug;38(4):1116-21. doi: 10.1042/BST0381116. Review.

PMID:
20659014
27.

Poly(A)-binding protein 1 partially relocalizes to the nucleus during herpes simplex virus type 1 infection in an ICP27-independent manner and does not inhibit virus replication.

Salaun C, MacDonald AI, Larralde O, Howard L, Lochtie K, Burgess HM, Brook M, Malik P, Gray NK, Graham SV.

J Virol. 2010 Sep;84(17):8539-48. doi: 10.1128/JVI.00668-10. Epub 2010 Jun 23.

28.

Effects of human papillomavirus type 16 E5 deletion mutants on epithelial morphology: functional characterization of each transmembrane domain.

Barbaresi S, Cortese MS, Quinn J, Ashrafi GH, Graham SV, Campo MS.

J Gen Virol. 2010 Feb;91(Pt 2):521-30. doi: 10.1099/vir.0.016295-0. Epub 2009 Oct 7.

PMID:
19812262
29.

The human papillomavirus 16 E2 protein is stabilised in S phase.

Johansson C, Graham SV, Dornan ES, Morgan IM.

Virology. 2009 Nov 25;394(2):194-9. doi: 10.1016/j.virol.2009.08.046. Epub 2009 Sep 24.

30.

RNA splicing factors regulated by HPV16 during cervical tumour progression.

Mole S, McFarlane M, Chuen-Im T, Milligan SG, Millan D, Graham SV.

J Pathol. 2009 Nov;219(3):383-91. doi: 10.1002/path.2608.

31.

The RNA stability regulator HuR regulates L1 protein expression in vivo in differentiating cervical epithelial cells.

Cumming SA, Chuen-Im T, Zhang J, Graham SV.

Virology. 2009 Jan 5;383(1):142-9. doi: 10.1016/j.virol.2008.10.003. Epub 2008 Nov 4.

32.

Human papillomavirus type 16 E2 protein transcriptionally activates the promoter of a key cellular splicing factor, SF2/ASF.

Mole S, Milligan SG, Graham SV.

J Virol. 2009 Jan;83(1):357-67. doi: 10.1128/JVI.01414-08. Epub 2008 Oct 22. Erratum in: J Virol. 2009 Apr;83(7):3418.

33.

Regulation of translation initiation by herpesviruses.

Smith RW, Graham SV, Gray NK.

Biochem Soc Trans. 2008 Aug;36(Pt 4):701-7. doi: 10.1042/BST0360701. Review.

PMID:
18631144
34.

Papillomavirus 3' UTR regulatory elements.

Graham SV.

Front Biosci. 2008 May 1;13:5646-63. Review.

PMID:
18508613
35.

Human papillomavirus type 16 late gene expression is regulated by cellular RNA processing factors in response to epithelial differentiation.

Cumming SA, Cheun-Im T, Milligan SG, Graham SV.

Biochem Soc Trans. 2008 Jun;36(Pt 3):522-4. doi: 10.1042/BST0360522. Review.

36.
37.

Analysis of novel human papillomavirus type 16 late mRNAs in differentiated W12 cervical epithelial cells.

Milligan SG, Veerapraditsin T, Ahamet B, Mole S, Graham SV.

Virology. 2007 Mar 30;360(1):172-81. Epub 2006 Nov 13.

38.

Regulation of splicing-associated SR proteins by HPV-16.

Mole S, Veerapraditsin T, McPhillips MG, Graham SV.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1145-7.

PMID:
17073771
39.

Analysis of regulatory motifs within HPV transcripts.

Cumming SA, Graham SV.

Methods Mol Med. 2005;119:291-315.

PMID:
16350408
40.

Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia.

Aasen T, Graham SV, Edward M, Hodgins MB.

Mol Cancer. 2005 Aug 9;4(1):31.

41.

Deregulation of RNA polymerase III transcription in cervical epithelium in response to high-risk human papillomavirus.

Daly NL, Arvanitis DA, Fairley JA, Gomez-Roman N, Morton JP, Graham SV, Spandidos DA, White RJ.

Oncogene. 2005 Jan 27;24(5):880-8.

PMID:
15592529
42.

SF2/ASF binds the human papillomavirus type 16 late RNA control element and is regulated during differentiation of virus-infected epithelial cells.

McPhillips MG, Veerapraditsin T, Cumming SA, Karali D, Milligan SG, Boner W, Morgan IM, Graham SV.

J Virol. 2004 Oct;78(19):10598-605.

44.

Nonsense-mediated decay breaks the circle?

Graham SV.

Biochem J. 2003 Aug 1;373(Pt 3):e5-6. Review.

45.
46.
47.

The human papillomavirus type 31 late 3' untranslated region contains a complex bipartite negative regulatory element.

Cumming SA, Repellin CE, McPhillips M, Radford JC, Clements JB, Graham SV.

J Virol. 2002 Jun;76(12):5993-6003.

48.

The human papillomavirus type 16 negative regulatory RNA element interacts with three proteins that act at different posttranscriptional levels.

Koffa MD, Graham SV, Takagaki Y, Manley JL, Clements JB.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4677-82.

49.
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