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The Leadership Gap: Supporting New Front line Leaders in Cancer Care.

Graham GL.

J Med Imaging Radiat Sci. 2019 Nov 8. pii: S1939-8654(19)30541-7. doi: 10.1016/j.jmir.2019.09.008. [Epub ahead of print]


Use of quantitative polymerase chain reaction (qPCR) for the diagnosis and monitoring of CNS leukaemia.

Yousafzai YM, Smith L, Smith A, Bhatti S, Gardiner M, Cousins A, Fee F, Chudleigh S, Spence A, Taylor W, Heaney N, Gibson B, Graham G, Halsey C.

Leuk Res. 2019 Sep 30;87:106232. doi: 10.1016/j.leukres.2019.106232. [Epub ahead of print] No abstract available.


Adoption of hypofractionated radiation therapy for early breast cancer in private practice: the GenesisCare experience 2014-2106.

Neville K, Dreosti M, Blakey D, Latham M, Izard MA, Young S, Graham G, O'Brien P.

J Med Imaging Radiat Oncol. 2019 Oct 10. doi: 10.1111/1754-9485.12964. [Epub ahead of print]


Rh single atoms on TiO2 dynamically respond to reaction conditions by adapting their site.

Tang Y, Asokan C, Xu M, Graham GW, Pan X, Christopher P, Li J, Sautet P.

Nat Commun. 2019 Oct 3;10(1):4488. doi: 10.1038/s41467-019-12461-6.


A long-acting, dual-agonist analogue of lamprey GLP-1 shows potent insulinotropic, β-cell protective, and anorexic activities and improves glucose homeostasis in high fat-fed mice.

Graham GV, McCloskey A, Abdel-Wahab YH, Conlon JM, Flatt PR.

Mol Cell Endocrinol. 2019 Sep 17;499:110584. doi: 10.1016/j.mce.2019.110584. [Epub ahead of print]


Pathogenic variants in CDC45 on the remaining allele in patients with a chromosome 22q11.2 deletion result in a novel autosomal recessive condition.

Unolt M, Kammoun M, Nowakowska B, Graham GE, Crowley TB, Hestand MS, Demaerel W, Geremek M, Emanuel BS, Zackai EH, Vermeesch JR, McDonald-McGinn D.

Genet Med. 2019 Sep 2. doi: 10.1038/s41436-019-0645-4. [Epub ahead of print]


Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis.

Abdel Shaheed C, Carland JE, Graham GG, Stocker SL, Smith G, Hicks M, Williams KM, Furlong T, MacDonald P, Greenfield JR, Smith FC, Chowdhury G, Day RO.

Br J Clin Pharmacol. 2019 Aug 31. doi: 10.1111/bcp.14107. [Epub ahead of print]


Determination of febuxostat in human plasma by high performance liquid chromatography (HPLC) with fluorescence-detection.

Kamel B, Williams KM, Graham GG, Norris RLG, Stocker SL, Carland JE, Pile KD, Day RO.

J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Sep 15;1126-1127:121764. doi: 10.1016/j.jchromb.2019.121764. Epub 2019 Aug 14.


Short and long-term effects of CDK4/6 inhibition on early stage breast cancer.

Kietzman WB, Graham GT, Ory V, Sharif G, Kushner MH, Gallanis GT, Kallakury B, Wellstein A, Riegel AT.

Mol Cancer Ther. 2019 Aug 26. pii: molcanther.0231.2019. doi: 10.1158/1535-7163.MCT-19-0231. [Epub ahead of print]


A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas.

Murakami S, Nemazanyy I, White SM, Chen H, Nguyen CDK, Graham GT, Saur D, Pende M, Yi C.

Dev Cell. 2019 Oct 7;51(1):113-128.e9. doi: 10.1016/j.devcel.2019.07.022. Epub 2019 Aug 22.


Comparison of the Area-Under-The-Curve for Vancomycin Estimated Using Compartmental and Non-compartmental Methods in Adult Patients with Normal Renal Function.

Shingde RV, Graham GG, Reuter SE, Carland JE, Day RO, Stocker SL.

Ther Drug Monit. 2019 Aug 16. doi: 10.1097/FTD.0000000000000690. [Epub ahead of print]


Potential influence of the corpus luteum on circulating reproductive and volume regulatory hormones, angiogenic and immunoregulatory factors in pregnant women.

Conrad KP, Graham GM, Chi YY, Zhai X, Li M, Williams RS, Rhoton-Vlasak A, Segal MS, Wood CE, Keller-Wood M.

Am J Physiol Endocrinol Metab. 2019 Oct 1;317(4):E677-E685. doi: 10.1152/ajpendo.00225.2019. Epub 2019 Aug 13.


EWS-FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex.

Selvanathan SP, Graham GT, Grego AR, Baker TM, Hogg JR, Simpson M, Batish M, Crompton B, Stegmaier K, Tomazou EM, Kovar H, Üren A, Toretsky JA.

Nucleic Acids Res. 2019 Oct 10;47(18):9619-9636. doi: 10.1093/nar/gkz699.


Application of Hereditary Renal Cell Carcinoma Risk Criteria to a Large Prospective Database.

Kushnir I, Kirk L, Mallick R, Kim RH, Graham GE, Breau RH, Lattouf JB, Violette PD, Pautler SE, Care M, Kapoor A, Jewett MAS, Wood L, Tanguay S, Heng DYC, Basappa NS, So A, Pouliot F, Reaume NM.

Clin Oncol (R Coll Radiol). 2019 Aug 1. pii: S0936-6555(19)30290-0. doi: 10.1016/j.clon.2019.07.010. [Epub ahead of print]


2019 ACC/AHA/ASE Key Data Elements and Definitions for Transthoracic Echocardiography: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Transthoracic Echocardiography) and the American Society of Echocardiography.

Writing Committee Members, Douglas PS, Carabello BA, Lang RM, Lopez L, Pellikka PA, Picard MH, Thomas JD, Varghese P, Wang TY, Weissman NJ, Wilgus R; ACC/AHA Task Force on Clinical Data Standards Members, Bozkurt B, Jneid H, Al-Khatib SM, Anderson HV, Gilstrap L, Graham GN, Jones GK, Kao D, Lopez L, Marcus G, Rymer J, Tcheng JE, Weintraub WS.

J Am Soc Echocardiogr. 2019 Sep;32(9):1161-1248. doi: 10.1016/j.echo.2019.05.006. Epub 2019 Jun 24. No abstract available.


The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents.

Spriano F, Chung EYL, Gaudio E, Tarantelli C, Cascione L, Napoli S, Jessen K, Carrassa L, Priebe V, Sartori G, Graham G, Selvanathan SP, Cavalli A, Rinaldi A, Kwee I, Testoni M, Genini D, Ye BH, Zucca E, Stathis A, Lannutti B, Toretsky JA, Bertoni F.

Clin Cancer Res. 2019 Aug 15;25(16):5167-5176. doi: 10.1158/1078-0432.CCR-18-2718. Epub 2019 Jun 10.


The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells.

Parasido E, Avetian GS, Naeem A, Graham G, Pishvaian M, Glasgow E, Mudambi S, Lee Y, Ihemelandu C, Choudhry M, Peran I, Banerjee PP, Avantaggiati ML, Bryant K, Baldelli E, Pierobon M, Liotta L, Petricoin E, Fricke ST, Sebastian A, Cozzitorto J, Loots GG, Kumar D, Byers S, Londin E, DiFeo A, Narla G, Winter J, Brody JR, Rodriguez O, Albanese C.

Mol Cancer Res. 2019 Sep;17(9):1815-1827. doi: 10.1158/1541-7786.MCR-19-0191. Epub 2019 Jun 4.


Placental chemokine compartmentalisation: A novel mammalian molecular control mechanism.

Lee KM, Wilson GJ, Pingen M, Fukuoka A, Hansell CAH, Bartolini R, Medina-Ruiz L, Graham GJ.

PLoS Biol. 2019 May 29;17(5):e3000287. doi: 10.1371/journal.pbio.3000287. eCollection 2019 May.


Deciphering the Role of a SLOG Superfamily Protein YpsA in Gram-Positive Bacteria.

Brzozowski RS, Huber M, Burroughs AM, Graham G, Walker M, Alva SS, Aravind L, Eswara PJ.

Front Microbiol. 2019 Apr 5;10:623. doi: 10.3389/fmicb.2019.00623. eCollection 2019.


Structural evolution of atomically dispersed Pt catalysts dictates reactivity.

DeRita L, Resasco J, Dai S, Boubnov A, Thang HV, Hoffman AS, Ro I, Graham GW, Bare SR, Pacchioni G, Pan X, Christopher P.

Nat Mater. 2019 Jul;18(7):746-751. doi: 10.1038/s41563-019-0349-9. Epub 2019 Apr 22.


Leukocyte Adhesion: Reconceptualizing Chemokine Presentation by Glycosaminoglycans.

Graham GJ, Handel TM, Proudfoot AEI.

Trends Immunol. 2019 Jun;40(6):472-481. doi: 10.1016/ Epub 2019 Apr 18. Review.


Restarting antidepressant and antipsychotic medication after intentional overdoses: need for evidence-based guidance.

Tay E, Sotiriou A, Graham GG, Wilhelm K, Snowden L, Day RO.

Ther Adv Psychopharmacol. 2019 Mar 29;9:2045125319836889. doi: 10.1177/2045125319836889. eCollection 2019. Review.


The association between left main coronary artery calcium and cardiovascular-specific and total mortality: The Coronary Artery Calcium Consortium.

Lahti SJ, Feldman DI, Dardari Z, Mirbolouk M, Orimoloye OA, Osei AD, Graham G, Rumberger J, Shaw L, Budoff MJ, Rozanski A, Miedema MD, Al-Mallah MH, Berman D, Nasir K, Blaha MJ.

Atherosclerosis. 2019 Jul;286:172-178. doi: 10.1016/j.atherosclerosis.2019.03.015. Epub 2019 Mar 24.


Coronary artery calcium scoring in low risk patients with family history of coronary heart disease: Validation of the SCCT guideline approach in the coronary artery calcium consortium.

Dudum R, Dzaye O, Mirbolouk M, Dardari ZA, Orimoloye OA, Budoff MJ, Berman DS, Rozanski A, Miedema MD, Nasir K, Rumberger JA, Shaw L, Whelton SP, Graham G, Blaha MJ.

J Cardiovasc Comput Tomogr. 2019 May - Jun;13(3):21-25. doi: 10.1016/j.jcct.2019.03.012. Epub 2019 Mar 27.


Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations.

Deslattes Mays A, Schmidt M, Graham G, Tseng E, Baybayan P, Sebra R, Sanda M, Mazarati JB, Riegel A, Wellstein A.

Genes (Basel). 2019 Mar 27;10(4). pii: E253. doi: 10.3390/genes10040253.


Role of Coronary Artery Calcium for Stratifying Cardiovascular Risk in Adults With Hypertension.

Uddin SMI, Mirbolouk M, Kianoush S, Orimoloye OA, Dardari Z, Whelton SP, Miedema MD, Nasir K, Rumberger JA, Shaw LJ, Berman DS, Budoff MJ, McEvoy JW, Matsushita K, Blaha MJ, Graham G.

Hypertension. 2019 May;73(5):983-989. doi: 10.1161/HYPERTENSIONAHA.118.12266.


Chemokine Receptor Redundancy and Specificity Are Context Dependent.

Dyer DP, Medina-Ruiz L, Bartolini R, Schuette F, Hughes CE, Pallas K, Vidler F, Macleod MKL, Kelly CJ, Lee KM, Hansell CAH, Graham GJ.

Immunity. 2019 Feb 19;50(2):378-389.e5. doi: 10.1016/j.immuni.2019.01.009.


Implantation of Acellular Nerve Allograft Using Nerve Connectors.

Isaacs J, Mallu S, Patel G, Kite A, Shah S, Graham GP.

Hand (N Y). 2019 Feb 19:1558944719828009. doi: 10.1177/1558944719828009. [Epub ahead of print]


A pilot eConsultation service in Eastern Ontario: bridging clinical genetics and primary care.

Bhola PT, Liddy C, Afkham A, Keely E, Graham GE.

Eur J Hum Genet. 2019 Jul;27(7):1026-1032. doi: 10.1038/s41431-019-0342-4. Epub 2019 Feb 18.


Extragenital Gonorrhea and Chlamydia Among Men and Women According to Type of Sexual Exposure.

Bamberger DM, Graham G, Dennis L, Gerkovich MM.

Sex Transm Dis. 2019 May;46(5):329-334. doi: 10.1097/OLQ.0000000000000967.


A Library of Analytic Indicators to Evaluate Effective Engagement with Consumer mHealth Apps for Chronic Conditions: Scoping Review.

Pham Q, Graham G, Carrion C, Morita PP, Seto E, Stinson JN, Cafazzo JA.

JMIR Mhealth Uhealth. 2019 Jan 18;7(1):e11941. doi: 10.2196/11941.


Racial Disparities in Patient Characteristics and Survival After Acute Myocardial Infarction.

Graham GN, Jones PG, Chan PS, Arnold SV, Krumholz HM, Spertus JA.

JAMA Netw Open. 2018 Nov 2;1(7):e184240. doi: 10.1001/jamanetworkopen.2018.4240.


An Analytics Platform to Evaluate Effective Engagement With Pediatric Mobile Health Apps: Design, Development, and Formative Evaluation.

Pham Q, Graham G, Lalloo C, Morita PP, Seto E, Stinson JN, Cafazzo JA.

JMIR Mhealth Uhealth. 2018 Dec 21;6(12):e11447. doi: 10.2196/11447.


A Mechanism of Resistance to Antibody-Targeted Immune Attack.

Aldeghaither DS, Zahavi DJ, Murray JC, Fertig EJ, Graham GT, Zhang YW, O'Connell A, Ma J, Jablonski SA, Weiner LM.

Cancer Immunol Res. 2019 Feb;7(2):230-243. doi: 10.1158/2326-6066.CIR-18-0266. Epub 2018 Dec 18.


The chemokine receptor CXCR2 contributes to murine adipocyte development.

Dyer DP, Nebot JB, Kelly CJ, Medina-Ruiz L, Schuette F, Graham GJ.

J Leukoc Biol. 2019 Mar;105(3):497-506. doi: 10.1002/JLB.1A0618-216RR. Epub 2018 Dec 5.


Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.

Vietsch EE, Graham GT, McCutcheon JN, Javaid A, Giaccone G, Marshall JL, Wellstein A.

Cancer Genet. 2018 Dec;228-229:131-142. doi: 10.1016/j.cancergen.2018.11.001. Epub 2018 Nov 9.


Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.

Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S.

Immunity. 2018 Dec 18;49(6):1062-1076.e6. doi: 10.1016/j.immuni.2018.09.018. Epub 2018 Nov 13.


Where we live: The impact of neighborhoods and community factors on cardiovascular health in the United States.

Xiao YK, Graham G.

Clin Cardiol. 2019 Jan;42(1):184-189. doi: 10.1002/clc.23107. Epub 2018 Nov 29. Review.


Glucagon-related peptides from phylogenetically ancient fish reveal new approaches to the development of dual GCGR and GLP1R agonists for type 2 diabetes therapy.

Graham GV, Conlon JM, Abdel-Wahab YH, Flatt PR.

Peptides. 2018 Dec;110:19-29. doi: 10.1016/j.peptides.2018.10.013. Epub 2018 Nov 1.


Deconvolution of octahedral Pt3Ni nanoparticle growth pathway from in situ characterizations.

Shen X, Zhang C, Zhang S, Dai S, Zhang G, Ge M, Pan Y, Sharkey SM, Graham GW, Hunt A, Waluyo I, Miller JT, Pan X, Peng Z.

Nat Commun. 2018 Oct 26;9(1):4485. doi: 10.1038/s41467-018-06900-z.


Glucagon-like peptides-1 from phylogenetically ancient fish show potent anti-diabetic activities by acting as dual GLP1R and GCGR agonists.

Graham GV, Conlon JM, Abdel-Wahab YH, Flatt PR.

Mol Cell Endocrinol. 2019 Jan 15;480:54-64. doi: 10.1016/j.mce.2018.10.011. Epub 2018 Oct 9.


An essential Staphylococcus aureus cell division protein directly regulates FtsZ dynamics.

Eswara PJ, Brzozowski RS, Viola MG, Graham G, Spanoudis C, Trebino C, Jha J, Aubee JI, Thompson KM, Camberg JL, Ramamurthi KS.

Elife. 2018 Oct 2;7. pii: e38856. doi: 10.7554/eLife.38856.


Comment on ''Massive' metformin overdose' by Chiew et al.

Graham GG.

Br J Clin Pharmacol. 2018 Dec;84(12):2938-2939. doi: 10.1111/bcp.13723. Epub 2018 Sep 12. No abstract available.


Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors.

Anderson ND, de Borja R, Young MD, Fuligni F, Rosic A, Roberts ND, Hajjar S, Layeghifard M, Novokmet A, Kowalski PE, Anaka M, Davidson S, Zarrei M, Id Said B, Schreiner LC, Marchand R, Sitter J, Gokgoz N, Brunga L, Graham GT, Fullam A, Pillay N, Toretsky JA, Yoshida A, Shibata T, Metzler M, Somers GR, Scherer SW, Flanagan AM, Campbell PJ, Schiffman JD, Shago M, Alexandrov LB, Wunder JS, Andrulis IL, Malkin D, Behjati S, Shlien A.

Science. 2018 Aug 31;361(6405). pii: eaam8419. doi: 10.1126/science.aam8419.


Diagnostic clarity of exome sequencing following negative comprehensive panel testing in the neonatal intensive care unit.

Kernohan KD, Hartley T, Naumenko S, Armour CM, Graham GE, Nikkel SM, Lines M, Geraghty MT, Richer J, Mears W, Boycott KM, Dyment DA.

Am J Med Genet A. 2018 Jul;176(7):1688-1691. doi: 10.1002/ajmg.a.38838. No abstract available.


The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis.

Hansell CAH, Fraser AR, Hayes AJ, Pingen M, Burt CL, Lee KM, Medina-Ruiz L, Brownlie D, Macleod MKL, Burgoyne P, Wilson GJ, Nibbs RJB, Graham GJ.

J Immunol. 2018 Oct 15;201(8):2510-2519. doi: 10.4049/jimmunol.1800131. Epub 2018 Aug 29.


Prevention of Lipid Peroxidation-derived Cyclic DNA Adduct and Mutation in High-Fat Diet-induced Hepatocarcinogenesis by Theaphenon E.

Coia H, Ma N, Hou Y, Dyba MD, Fu Y, Cruz MI, Benitez C, Graham GT, McCutcheon JN, Zheng YL, Sun B, Kallakury BV, Ma J, Fang HB, Berry DL, Muralidaran V, Chung FL.

Cancer Prev Res (Phila). 2018 Oct;11(10):665-676. doi: 10.1158/1940-6207.CAPR-18-0160. Epub 2018 Aug 21.


Disorganized Patterns of Sulcal Position in Fetal Brains with Agenesis of Corpus Callosum.

Tarui T, Madan N, Farhat N, Kitano R, Ceren Tanritanir A, Graham G, Gagoski B, Craig A, Rollins CK, Ortinau C, Iyer V, Pienaar R, Bianchi DW, Grant PE, Im K.

Cereb Cortex. 2018 Sep 1;28(9):3192-3203. doi: 10.1093/cercor/bhx191.


A qualitative study of clinical champions in context: Clinical champions across three levels of acute care.

Flanagan ME, Plue L, Miller KK, Schmid AA, Myers L, Graham G, Miech EJ, Williams LS, Damush TM.

SAGE Open Med. 2018 Aug 1;6:2050312118792426. doi: 10.1177/2050312118792426. eCollection 2018.


The atypical chemokine receptor-2 does not alter corneal graft survival but regulates early stage of corneal graft-induced lymphangiogenesis.

Yu T, Forrester JV, Graham GJ, Kuffova L.

Graefes Arch Clin Exp Ophthalmol. 2018 Oct;256(10):1875-1882. doi: 10.1007/s00417-018-4070-1. Epub 2018 Jul 27.

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