Sort by
Items per page

Send to

Choose Destination

Search results

Items: 39


Simultaneous Determination of Biliary and Intestinal Cholesterol Secretion Reveals That CETP (Cholesteryl Ester Transfer Protein) Alters Elimination Route in Mice.

Li J, Pijut SS, Wang Y, Ji A, Kaur R, Temel RE, van der Westhuyzen DR, Graf GA.

Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):1986-1995. doi: 10.1161/ATVBAHA.119.312952. Epub 2019 Aug 29.


Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins.

Allen RM, Zhao S, Ramirez Solano MA, Zhu W, Michell DL, Wang Y, Shyr Y, Sethupathy P, Linton MF, Graf GA, Sheng Q, Vickers KC.

J Extracell Vesicles. 2018 Aug 13;7(1):1506198. doi: 10.1080/20013078.2018.1506198. eCollection 2018.


ABCG5 and ABCG8: more than a defense against xenosterols.

Patel SB, Graf GA, Temel RE.

J Lipid Res. 2018 Jul;59(7):1103-1113. doi: 10.1194/jlr.R084244. Epub 2018 May 4. Review.


Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.

Rotroff DM, Pijut SS, Marvel SW, Jack JR, Havener TM, Pujol A, Schluter A, Graf GA, Ginsberg HN, Shah HS, Gao H, Morieri ML, Doria A, Mychaleckyi JC, McLeod HL, Buse JB, Wagner MJ, Motsinger-Reif AA; ACCORD/ACCORDion Investigators.

Clin Pharmacol Ther. 2018 Apr;103(4):712-721. doi: 10.1002/cpt.798. Epub 2017 Nov 3.


Para-bile-osis Establishes a Role for Nonbiliary Macrophage to Feces Reverse Cholesterol Transport.

Brown JM, Temel RE, Graf GA.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):738-739. doi: 10.1161/ATVBAHA.117.309224. No abstract available.


Effect of peripheral circadian dysfunction on metabolic disease in response to a diabetogenic diet.

Pijut SS, Corbett DE, Wang Y, Li J, Charnigo RJ, Graf GA.

Am J Physiol Endocrinol Metab. 2016 Jun 1;310(11):E900-11. doi: 10.1152/ajpendo.00328.2015. Epub 2016 Apr 5.


GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice.

Wang Y, Su K, Sabeva NS, Ji A, van der Westhuyzen DR, Foufelle F, Gao X, Graf GA.

Metabolism. 2015 Nov;64(11):1435-43. doi: 10.1016/j.metabol.2015.08.005. Epub 2015 Aug 15.


The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination.

Wang Y, Liu X, Pijut SS, Li J, Horn J, Bradford EM, Leggas M, Barrett TA, Graf GA.

J Lipid Res. 2015 Apr;56(4):810-20. doi: 10.1194/jlr.M053454. Epub 2015 Jan 29.


ABCD2 identifies a subclass of peroxisomes in mouse adipose tissue.

Liu X, Liu J, Lester JD, Pijut SS, Graf GA.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):129-34. doi: 10.1016/j.bbrc.2014.11.046. Epub 2014 Nov 24.


ABCD2 alters peroxisome proliferator-activated receptor α signaling in vitro, but does not impair responses to fenofibrate therapy in a mouse model of diet-induced obesity.

Liu X, Liu J, Liang S, Schlüter A, Fourcade S, Aslibekyan S, Pujol A, Graf GA.

Mol Pharmacol. 2014 Nov;86(5):505-13. doi: 10.1124/mol.114.092742. Epub 2014 Aug 14.


Acceleration of biliary cholesterol secretion restores glycemic control and alleviates hypertriglyceridemia in obese db/db mice.

Su K, Sabeva NS, Wang Y, Liu X, Lester JD, Liu J, Liang S, Graf GA.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):26-33. doi: 10.1161/ATVBAHA.113.302355. Epub 2013 Nov 7.


Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice.

Salous AK, Panchatcharam M, Sunkara M, Mueller P, Dong A, Wang Y, Graf GA, Smyth SS, Morris AJ.

J Lipid Res. 2013 Oct;54(10):2775-84. doi: 10.1194/jlr.M039685. Epub 2013 Aug 15.


New developments in selective cholesteryl ester uptake.

Meyer JM, Graf GA, van der Westhuyzen DR.

Curr Opin Lipidol. 2013 Oct;24(5):386-92. doi: 10.1097/MOL.0b013e3283638042. Review.


The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation.

Su K, Sabeva NS, Liu J, Wang Y, Bhatnagar S, van der Westhuyzen DR, Graf GA.

J Biol Chem. 2012 Aug 17;287(34):28564-75. doi: 10.1074/jbc.M112.360081. Epub 2012 Jun 19.


The absence of ABCD2 sensitizes mice to disruptions in lipid metabolism by dietary erucic acid.

Liu J, Liang S, Liu X, Brown JA, Newman KE, Sunkara M, Morris AJ, Bhatnagar S, Li X, Pujol A, Graf GA.

J Lipid Res. 2012 Jun;53(6):1071-9. doi: 10.1194/jlr.M022160. Epub 2012 Apr 6.


Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells.

Sabeva NS, McPhaul CM, Li X, Cory TJ, Feola DJ, Graf GA.

J Nutr Biochem. 2011 Aug;22(8):777-83. doi: 10.1016/j.jnutbio.2010.07.002. Epub 2010 Dec 15.


Cyclooxygenase-2 deficiency attenuates adipose tissue differentiation and inflammation in mice.

Ghoshal S, Trivedi DB, Graf GA, Loftin CD.

J Biol Chem. 2011 Jan 7;286(1):889-98. doi: 10.1074/jbc.M110.139139. Epub 2010 Oct 20.


ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat.

Liu J, Sabeva NS, Bhatnagar S, Li XA, Pujol A, Graf GA.

J Lipid Res. 2010 Jan;51(1):162-8. doi: 10.1194/jlr.M900237-JLR200.


The ABCG5 ABCG8 sterol transporter and phytosterols: implications for cardiometabolic disease.

Sabeva NS, Liu J, Graf GA.

Curr Opin Endocrinol Diabetes Obes. 2009 Apr;16(2):172-7. Review.


Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster.

Burke KT, Colvin PL, Myatt L, Graf GA, Schroeder F, Woollett LA.

J Lipid Res. 2009 Jun;50(6):1146-55. doi: 10.1194/jlr.M800538-JLR200. Epub 2009 Jan 3.


Diabetic HDL-associated myristic acid inhibits acetylcholine-induced nitric oxide generation by preventing the association of endothelial nitric oxide synthase with calmodulin.

White J, Guerin T, Swanson H, Post S, Zhu H, Gong M, Liu J, Everson WV, Li XA, Graf GA, Ballard HO, Ross SA, Smart EJ.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C295-305. Epub 2007 Oct 31. Retraction in: Am J Physiol Cell Physiol. 2013 Apr 15;304(8):C812.


Defects in the leptin axis reduce abundance of the ABCG5-ABCG8 sterol transporter in liver.

Sabeva NS, Rouse EJ, Graf GA.

J Biol Chem. 2007 Aug 3;282(31):22397-405. Epub 2007 Jun 7.


Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8.

Zhang DW, Graf GA, Gerard RD, Cohen JC, Hobbs HH.

J Biol Chem. 2006 Feb 17;281(7):4507-16. Epub 2005 Dec 12.


Missense mutations in ABCG5 and ABCG8 disrupt heterodimerization and trafficking.

Graf GA, Cohen JC, Hobbs HH.

J Biol Chem. 2004 Jun 4;279(23):24881-8. Epub 2004 Mar 30.


ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion.

Graf GA, Yu L, Li WP, Gerard R, Tuma PL, Cohen JC, Hobbs HH.

J Biol Chem. 2003 Nov 28;278(48):48275-82. Epub 2003 Sep 22.


Genetic defenses against hypercholesterolemia.

Hobbs HH, Graf GA, Yu L, Wilund KR, Cohen JC.

Cold Spring Harb Symp Quant Biol. 2002;67:499-505. Review. No abstract available.


Effect of estrogen on scavenger receptor BI expression in the rat.

Stangl H, Graf GA, Yu L, Cao G, Wyne K.

J Endocrinol. 2002 Dec;175(3):663-72.


Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface.

Graf GA, Li WP, Gerard RD, Gelissen I, White A, Cohen JC, Hobbs HH.

J Clin Invest. 2002 Sep;110(5):659-69.


17beta-Estradiol promotes the up-regulation of SR-BII in HepG2 cells and in rat livers.

Graf GA, Roswell KL, Smart EJ.

J Lipid Res. 2001 Sep;42(9):1444-9. Retraction in: J Lipid Res. 2013 Apr;54(4):1151.


Effect of oxytocin on expression of cytosolic phospholipase A2 mRNA and protein in ovine endometrial tissue in vivo.

Burns PD, Graf GA, Hayes SH, Silvia WJ.

Domest Anim Endocrinol. 2000 Nov;19(4):237-46.


Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.

Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH.

Science. 2000 Dec 1;290(5497):1771-5.


Class B scavenger receptors, caveolae and cholesterol homeostasis.

Graf GA, Matveev SV, Smart EJ.

Trends Cardiovasc Med. 1999 Nov;9(8):221-5. Review.


Caveolins, liquid-ordered domains, and signal transduction.

Smart EJ, Graf GA, McNiven MA, Sessa WC, Engelman JA, Scherer PE, Okamoto T, Lisanti MP.

Mol Cell Biol. 1999 Nov;19(11):7289-304. Review. No abstract available.


Expression of a cytosolic phospholipase A2 by ovine endometrium on days 11-14 of a simulated oestrous cycle.

Graf GA, Burns PD, Silvia WJ.

J Reprod Fertil. 1999 Mar;115(2):357-63.


The class B, type I scavenger receptor promotes the selective uptake of high density lipoprotein cholesterol ethers into caveolae.

Graf GA, Connell PM, van der Westhuyzen DR, Smart EJ.

J Biol Chem. 1999 Apr 23;274(17):12043-8.


SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells.

Webb NR, Connell PM, Graf GA, Smart EJ, de Villiers WJ, de Beer FC, van der Westhuyzen DR.

J Biol Chem. 1998 Jun 12;273(24):15241-8.


Effect of oxytocin on concentrations of prostaglandin H synthase-2 mRNA in ovine endometrial tissue in vivo.

Burns PD, Tsai SJ, Wiltbank MC, Hayes SH, Graf GA, Silvia WJ.

Endocrinology. 1997 Dec;138(12):5637-40.


Cellular mechanisms by which oxytocin stimulates uterine PGF2 alpha synthesis in bovine endometrium: roles of phospholipases C and A2.

Burns PD, Graf GA, Hayes SH, Silvia WJ.

Domest Anim Endocrinol. 1997 May;14(3):181-91.


Supplemental Content

Support Center