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Items: 1 to 50 of 164

1.

Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons.

Svahn AJ, Don EK, Badrock AP, Cole NJ, Graeber MB, Yerbury JJ, Chung R, Morsch M.

Acta Neuropathol. 2018 Sep;136(3):445-459. doi: 10.1007/s00401-018-1875-2. Epub 2018 Jun 25.

2.

Developing the field of neurogenetics.

Müller U, Auburger G, Graeber MB, Ptacek LJ.

Neurogenetics. 2017 Dec;18(4):183-184. doi: 10.1007/s10048-017-0530-8. No abstract available.

PMID:
29164503
3.

Calcium-axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes.

Buljan VA, Graeber MB, Holsinger RMD, Brown D, Hambly BD, Delikatny EJ, Vuletic VR, Krebs XN, Tomas IB, Bohorquez-Florez JJ, Liu GJ, Banati RB.

J Biol Phys. 2018 Mar;44(1):53-80. doi: 10.1007/s10867-017-9475-2. Epub 2017 Oct 31.

PMID:
29090363
4.

The 18-kDa Translocator Protein as a CNS Drug Target: Finding Our Way Through the Neuroinflammation Fog.

Filiou MD, Banati RB, Graeber MB.

CNS Neurol Disord Drug Targets. 2017;16(9):990-999. doi: 10.2174/1871527316666171004125107.

PMID:
28982340
5.

Microglioma in a child - a further case in support of the microglioma entity and distinction from histiocytic sarcoma.

Mathews A, Ohsawa K, Buckland ME, Kesavadas C, Ratheesan K, Kusumakumary P, Burger PC, Kohsaka S, Graeber MB.

Clin Neuropathol. 2016 Sep-Oct;35(5):302-13. doi: 10.5414/NP300938.

PMID:
27191913
6.

miR-124 Contributes to the functional maturity of microglia.

Svahn AJ, Giacomotto J, Graeber MB, Rinkwitz S, Becker TS.

Dev Neurobiol. 2016 May;76(5):507-18. doi: 10.1002/dneu.22328. Epub 2015 Jul 25.

7.

Erratum to: Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium.

Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Ince PG, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Nilsson T, Parchi P, Patsouris E, Revesz T, Roggendorf W, Rozemuller A, Seilhean D, Streichenberger N, Thal DR, Wharton SB, Kretzschmar H.

J Neural Transm (Vienna). 2015 Jul;122(7):973-4. doi: 10.1007/s00702-014-1337-5. No abstract available.

PMID:
25418279
8.

Positron emission tomography and functional characterization of a complete PBR/TSPO knockout.

Banati RB, Middleton RJ, Chan R, Hatty CR, Kam WW, Quin C, Graeber MB, Parmar A, Zahra D, Callaghan P, Fok S, Howell NR, Gregoire M, Szabo A, Pham T, Davis E, Liu GJ.

Nat Commun. 2014 Nov 19;5:5452. doi: 10.1038/ncomms6452.

9.

Emergent properties of microglia.

Svahn AJ, Becker TS, Graeber MB.

Brain Pathol. 2014 Nov;24(6):665-70. doi: 10.1111/bpa.12195.

PMID:
25345896
10.

Neuroinflammation: no rose by any other name.

Graeber MB.

Brain Pathol. 2014 Nov;24(6):620-2. doi: 10.1111/bpa.12192. No abstract available.

PMID:
25345892
11.

Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium.

Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Ince PG, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Nilsson T, Parchi P, Patsouris E, Revesz T, Roggendorf W, Rozemuller A, Seilhean D, Streichenberger N, Thal DR, Wharton SB, Kretzschmar H.

J Neural Transm (Vienna). 2015 Jul;122(7):957-72. doi: 10.1007/s00702-014-1304-1. Epub 2014 Sep 20. Erratum in: J Neural Transm (Vienna). 2015 Jul;122(7):973-4.

12.

'Neuroinflammation' differs categorically from inflammation: transcriptomes of Alzheimer's disease, Parkinson's disease, schizophrenia and inflammatory diseases compared.

Filiou MD, Arefin AS, Moscato P, Graeber MB.

Neurogenetics. 2014 Aug;15(3):201-12. doi: 10.1007/s10048-014-0409-x. Epub 2014 Jun 15.

PMID:
24928144
13.

Up-regulation of matrix metallopeptidase 12 in motor neurons undergoing synaptic stripping.

Sajjan S, Holsinger RM, Fok S, Ebrahimkhani S, Rollo JL, Banati RB, Graeber MB.

Neuroscience. 2014 Aug 22;274:331-40. doi: 10.1016/j.neuroscience.2014.05.052. Epub 2014 Jun 4.

PMID:
24907602
14.

Microglial proliferation in the brain of chronic alcoholics with hepatic encephalopathy.

Dennis CV, Sheahan PJ, Graeber MB, Sheedy DL, Kril JJ, Sutherland GT.

Metab Brain Dis. 2014 Dec;29(4):1027-39. doi: 10.1007/s11011-013-9469-0. Epub 2013 Dec 19.

15.

The potential for genetically altered microglia to influence glioma treatment.

Li W, Holsinger RM, Kruse CA, Flügel A, Graeber MB.

CNS Neurol Disord Drug Targets. 2013 Sep;12(6):750-62. Review.

16.

Glutathione relates to neuropsychological functioning in mild cognitive impairment.

Duffy SL, Lagopoulos J, Hickie IB, Diamond K, Graeber MB, Lewis SJ, Naismith SL.

Alzheimers Dement. 2014 Jan;10(1):67-75. doi: 10.1016/j.jalz.2013.01.005. Epub 2013 May 18.

PMID:
23688577
17.

A presenilin 1 mutation in the first case of Alzheimer's disease.

Müller U, Winter P, Graeber MB.

Lancet Neurol. 2013 Feb;12(2):129-30. doi: 10.1016/S1474-4422(12)70307-1. Epub 2012 Dec 14. No abstract available.

PMID:
23246540
18.

Courage, luck and patience: in celebration of the 80th birthday of Georg W. Kreutzberg.

Graeber MB, Banati RB, Flügel A, Streit WJ, Tetzlaff W.

Acta Neuropathol. 2012 Oct;124(4):593-8. doi: 10.1007/s00401-012-1033-1. Epub 2012 Aug 12. No abstract available.

PMID:
22886135
19.

The role of glia in late-life depression.

Paradise MB, Naismith SL, Norrie LM, Graeber MB, Hickie IB.

Int Psychogeriatr. 2012 Dec;24(12):1878-90. doi: 10.1017/S1041610212000828. Epub 2012 Jul 3. Review.

PMID:
22874475
20.

The need to unify neuropathological assessments of vascular alterations in the ageing brain: multicentre survey by the BrainNet Europe consortium.

Alafuzoff I, Gelpi E, Al-Sarraj S, Arzberger T, Attems J, Bodi I, Bogdanovic N, Budka H, Bugiani O, Englund E, Ferrer I, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Höftberger R, Ironside JW, Jellinger K, Kavantzas N, King A, Korkolopoulou P, Kovács GG, Meyronet D, Monoranu C, Parchi P, Patsouris E, Roggendorf W, Rozemuller A, Seilhean D, Streichenberger N, Thal DR, Wharton SB, Kretzschmar H.

Exp Gerontol. 2012 Nov;47(11):825-33. doi: 10.1016/j.exger.2012.06.001. Epub 2012 Jun 15.

PMID:
22705312
21.

Development of ramified microglia from early macrophages in the zebrafish optic tectum.

Svahn AJ, Graeber MB, Ellett F, Lieschke GJ, Rinkwitz S, Bennett MR, Becker TS.

Dev Neurobiol. 2013 Jan;73(1):60-71. doi: 10.1002/dneu.22039. Epub 2012 Jul 20.

22.

The molecular profile of microglia under the influence of glioma.

Li W, Graeber MB.

Neuro Oncol. 2012 Aug;14(8):958-78. doi: 10.1093/neuonc/nos116. Epub 2012 May 9. Review.

23.

Multiple mechanisms of microglia: a gatekeeper's contribution to pain states.

Graeber MB, Christie MJ.

Exp Neurol. 2012 Apr;234(2):255-61. doi: 10.1016/j.expneurol.2012.01.007. Epub 2012 Jan 16. Review.

PMID:
22273537
24.

Alois Alzheimer's case, Auguste D., did not carry the N141I mutation in PSEN2 characteristic of Alzheimer disease in Volga Germans.

Müller U, Winter P, Graeber MB.

Arch Neurol. 2011 Sep;68(9):1210-1, author reply 1211. doi: 10.1001/archneurol.2011.218. No abstract available.

PMID:
21911706
25.

Role of microglia in CNS inflammation.

Graeber MB, Li W, Rodriguez ML.

FEBS Lett. 2011 Dec 1;585(23):3798-805. doi: 10.1016/j.febslet.2011.08.033. Epub 2011 Aug 30. Review.

26.

Up-regulation of metallothionein gene expression in parkinsonian astrocytes.

Michael GJ, Esmailzadeh S, Moran LB, Christian L, Pearce RK, Graeber MB.

Neurogenetics. 2011 Nov;12(4):295-305. doi: 10.1007/s10048-011-0294-5. Epub 2011 Jul 29.

PMID:
21800131
27.

Bone marrow-derived microglia in pilocytic astrocytoma.

AlShakweer W, Alwelaie Y, Mankung AM, Graeber MB.

Front Biosci (Elite Ed). 2011 Jan 1;3:371-9.

PMID:
21196317
28.

Changing face of microglia.

Graeber MB.

Science. 2010 Nov 5;330(6005):783-8. doi: 10.1126/science.1190929. Review.

PMID:
21051630
29.

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grünblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, Federoff HJ, Wüllner U, Papapetropoulos S, Youdim MB, Cantuti-Castelvetri I, Young AB, Vance JM, Davis RL, Hedreen JC, Adler CH, Beach TG, Graeber MB, Middleton FA, Rochet JC, Scherzer CR; Global PD Gene Expression (GPEX) Consortium.

Sci Transl Med. 2010 Oct 6;2(52):52ra73. doi: 10.1126/scitranslmed.3001059.

30.

Microglia: biology and pathology.

Graeber MB, Streit WJ.

Acta Neuropathol. 2010 Jan;119(1):89-105. doi: 10.1007/s00401-009-0622-0. Epub 2009 Dec 13. Review.

PMID:
20012873
31.

Homocysteine-induced endoplasmic reticulum protein (herp) is up-regulated in parkinsonian substantia nigra and present in the core of Lewy bodies.

Slodzinski H, Moran LB, Michael GJ, Wang B, Novoselov S, Cheetham ME, Pearce RK, Graeber MB.

Clin Neuropathol. 2009 Sep-Oct;28(5):333-43.

32.

Parkinson disease: extranigral, multisystem, and {alpha}-synuclein "plus".

Kalaitzakis ME, Graeber MB, Gentleman SM, Pearce RK.

Arch Neurol. 2009 Jul;66(7):914-5; author reply 915-6. doi: 10.1001/archneurol.2009.140. No abstract available.

PMID:
19597100
33.

Evidence against a reliable staging system of alpha-synuclein pathology in Parkinson's disease.

Kalaitzakis ME, Graeber MB, Gentleman SM, Pearce RK.

Neuropathol Appl Neurobiol. 2009 Feb;35(1):125-6. doi: 10.1111/j.1365-2990.2008.00998.x. No abstract available.

PMID:
19187066
34.

Biomarkers for Parkinson's disease.

Graeber MB.

Exp Neurol. 2009 Apr;216(2):249-53. doi: 10.1016/j.expneurol.2008.12.017. Epub 2009 Jan 7. Review.

PMID:
19166835
35.

DnaJB6 is present in the core of Lewy bodies and is highly up-regulated in parkinsonian astrocytes.

Durrenberger PF, Filiou MD, Moran LB, Michael GJ, Novoselov S, Cheetham ME, Clark P, Pearce RK, Graeber MB.

J Neurosci Res. 2009 Jan;87(1):238-45. doi: 10.1002/jnr.21819.

PMID:
18711724
36.

Dementia and visual hallucinations associated with limbic pathology in Parkinson's disease.

Kalaitzakis ME, Christian LM, Moran LB, Graeber MB, Pearce RK, Gentleman SM.

Parkinsonism Relat Disord. 2009 Mar;15(3):196-204. doi: 10.1016/j.parkreldis.2008.05.007. Epub 2008 Jul 7.

PMID:
18602855
37.

Nigral neurons are likely to die of a mechanism other than classical apoptosis in Parkinson's disease.

Graeber MB, Grasbon-Frodl E, Abell-Aleff P, Kösel S.

Parkinsonism Relat Disord. 1999 Dec;5(4):187-92.

PMID:
18591139
38.

Controversies over the staging of alpha-synuclein pathology in Parkinson's disease.

Kalaitzakis ME, Graeber MB, Gentleman SM, Pearce RK.

Acta Neuropathol. 2008 Jul;116(1):125-8; author reply 129-31. doi: 10.1007/s00401-008-0381-3. Epub 2008 Apr 30. No abstract available.

PMID:
18446352
39.

Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium.

Alafuzoff I, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Braak H, Bugiani O, Del-Tredici K, Ferrer I, Gelpi E, Giaccone G, Graeber MB, Ince P, Kamphorst W, King A, Korkolopoulou P, Kovács GG, Larionov S, Meyronet D, Monoranu C, Parchi P, Patsouris E, Roggendorf W, Seilhean D, Tagliavini F, Stadelmann C, Streichenberger N, Thal DR, Wharton SB, Kretzschmar H.

Brain Pathol. 2008 Oct;18(4):484-96. doi: 10.1111/j.1750-3639.2008.00147.x. Epub 2008 Mar 26.

40.

Twenty-first century brain banking: at the crossroads.

Graeber MB.

Acta Neuropathol. 2008 May;115(5):493-6. doi: 10.1007/s00401-008-0363-5.

PMID:
18347804
41.

Striatal beta-amyloid deposition in Parkinson disease with dementia.

Kalaitzakis ME, Graeber MB, Gentleman SM, Pearce RK.

J Neuropathol Exp Neurol. 2008 Feb;67(2):155-61. doi: 10.1097/NEN.0b013e31816362aa.

PMID:
18219254
42.

Towards a pathway definition of Parkinson's disease: a complex disorder with links to cancer, diabetes and inflammation.

Moran LB, Graeber MB.

Neurogenetics. 2008 Feb;9(1):1-13. doi: 10.1007/s10048-007-0116-y. Epub 2008 Jan 12.

43.

The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of alpha-synuclein staging.

Kalaitzakis ME, Graeber MB, Gentleman SM, Pearce RK.

Neuropathol Appl Neurobiol. 2008 Jun;34(3):284-95. Epub 2007 Dec 5.

PMID:
18053026
44.

Neuronal pentraxin II is highly upregulated in Parkinson's disease and a novel component of Lewy bodies.

Moran LB, Hickey L, Michael GJ, Derkacs M, Christian LM, Kalaitzakis ME, Pearce RK, Graeber MB.

Acta Neuropathol. 2008 Apr;115(4):471-8. Epub 2007 Nov 7.

45.

Microglia in gemistocytic astrocytomas.

Geranmayeh F, Scheithauer BW, Spitzer C, Meyer FB, Svensson-Engwall AC, Graeber MB.

Neurosurgery. 2007 Jan;60(1):159-66; discussion 166.

PMID:
17228265
46.

The medial and lateral substantia nigra in Parkinson's disease: mRNA profiles associated with higher brain tissue vulnerability.

Duke DC, Moran LB, Pearce RK, Graeber MB.

Neurogenetics. 2007 Apr;8(2):83-94. Epub 2007 Jan 9.

PMID:
17211632
47.

Analysis of alpha-synuclein, dopamine and parkin pathways in neuropathologically confirmed parkinsonian nigra.

Moran LB, Croisier E, Duke DC, Kalaitzakis ME, Roncaroli F, Deprez M, Dexter DT, Pearce RK, Graeber MB.

Acta Neuropathol. 2007 Mar;113(3):253-63. Epub 2007 Jan 4.

48.

Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo.

Harris JE, Nuttall RK, Elkington PT, Green JA, Horncastle DE, Graeber MB, Edwards DR, Friedland JS.

J Immunol. 2007 Jan 15;178(2):1199-207.

49.

The microglial gene regulatory network activated by interferon-gamma.

Moran LB, Duke DC, Graeber MB.

J Neuroimmunol. 2007 Feb;183(1-2):1-6. Epub 2006 Dec 22.

PMID:
17188367
50.

IFNgamma synergizes with IL-1beta to up-regulate MMP-9 secretion in a cellular model of central nervous system tuberculosis.

Harris JE, Fernandez-Vilaseca M, Elkington PT, Horncastle DE, Graeber MB, Friedland JS.

FASEB J. 2007 Feb;21(2):356-65. Epub 2006 Dec 11.

PMID:
17158965

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