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Items: 1 to 50 of 73

1.

A summary on cutting edge advancements in sterilization and cleaning technologies in medical, food, and drug industries, and its applicability to spacecraft hardware.

Gradini R, Chen F, Tan R, Newlin L.

Life Sci Space Res (Amst). 2019 Nov;23:31-49. doi: 10.1016/j.lssr.2019.05.002. Epub 2019 May 15.

PMID:
31791604
2.

Serum 25-hydroxy vitamin D levels in essential hypertension.

Granato T, Anastasi E, Viggiani V, Occhiuzzi F, Angeloni A, Gradini R, Suppa M.

J Biol Regul Homeost Agents. 2018 Nov-Dec;32(6):1599-1604.

PMID:
30574772
3.

Rusty Microglia: Trainers of Innate Immunity in Alzheimer's Disease.

Sfera A, Gradini R, Cummings M, Diaz E, Price AI, Osorio C.

Front Neurol. 2018 Dec 4;9:1062. doi: 10.3389/fneur.2018.01062. eCollection 2018. Review.

4.

mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors.

Notartomaso S, Nakao H, Mascio G, Scarselli P, Cannella M, Zappulla C, Madonna M, Motolese M, Gradini R, Liberatore F, Zonta M, Carmignoto G, Battaglia G, Bruno V, Watanabe M, Aiba A, Nicoletti F.

Sci Rep. 2018 Sep 6;8(1):13361. doi: 10.1038/s41598-018-31369-7.

5.

Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain.

Notartomaso S, Mascio G, Bernabucci M, Zappulla C, Scarselli P, Cannella M, Imbriglio T, Gradini R, Battaglia G, Bruno V, Nicoletti F.

Mol Pain. 2017 Jan;13:1744806917697009. doi: 10.1177/1744806917697009.

6.

The α2δ Subunit and Absence Epilepsy: Beyond Calcium Channels?

Celli R, Santolini I, Guiducci M, van Luijtelaar G, Parisi P, Striano P, Gradini R, Battaglia G, Ngomba RT, Nicoletti F.

Curr Neuropharmacol. 2017;15(6):918-925. doi: 10.2174/1570159X15666170309105451. Review.

7.

Sinonasal adenocarcinoma in a patient without exposure to risk factors Case report and review of the literature.

Izzo L, Izzo S, Di Cello P, Vollono L, Violante O, Gradini R, Izzo P.

Ann Ital Chir. 2016 Jul 29;87. pii: S2239253X16025019. Review.

PMID:
27830670
8.

Expression of the K+/Cl- cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors.

Notartomaso S, Mascio G, Scarselli P, Martinello K, Fucile S, Gradini R, Bruno V, Battaglia G, Nicoletti F.

Neuropharmacology. 2017 Mar 15;115:51-59. doi: 10.1016/j.neuropharm.2016.07.032. Epub 2016 Aug 3.

PMID:
27498071
9.

Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia.

Fazio F, Lionetto L, Curto M, Iacovelli L, Cavallari M, Zappulla C, Ulivieri M, Napoletano F, Capi M, Corigliano V, Scaccianoce S, Caruso A, Miele J, De Fusco A, Di Menna L, Comparelli A, De Carolis A, Gradini R, Nisticò R, De Blasi A, Girardi P, Bruno V, Battaglia G, Nicoletti F, Simmaco M.

Sci Rep. 2015 Dec 8;5:17799. doi: 10.1038/srep17799.

10.

Proteomic and epigenomic markers of sepsis-induced delirium (SID).

Sfera A, Price AI, Gradini R, Cummings M, Osorio C.

Front Mol Biosci. 2015 Oct 26;2:59. doi: 10.3389/fmolb.2015.00059. eCollection 2015.

11.

Delirium from the gliocentric perspective.

Sfera A, Osorio C, Price AI, Gradini R, Cummings M.

Front Cell Neurosci. 2015 May 11;9:171. doi: 10.3389/fncel.2015.00171. eCollection 2015.

12.

Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism.

Cannella M, Motolese M, Bucci D, Molinaro G, Gradini R, Bruno V, Nicoletti F, Battaglia G.

Neuropharmacology. 2015 Aug;95:50-8. doi: 10.1016/j.neuropharm.2015.02.024. Epub 2015 Mar 5.

PMID:
25747602
13.

Metabotropic glutamate receptors as drug targets: what's new?

Nicoletti F, Bruno V, Ngomba RT, Gradini R, Battaglia G.

Curr Opin Pharmacol. 2015 Feb;20:89-94. doi: 10.1016/j.coph.2014.12.002. Epub 2014 Dec 12. Review.

PMID:
25506748
14.

Neurodegeneration behind bars: from molecules to jurisprudence.

Sfera A, Osorio C, Gradini R, Price A.

Front Psychiatry. 2014 Aug 27;5:115. doi: 10.3389/fpsyt.2014.00115. eCollection 2014. Review. No abstract available.

15.

Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1.

Notartomaso S, Zappulla C, Biagioni F, Cannella M, Bucci D, Mascio G, Scarselli P, Fazio F, Weisz F, Lionetto L, Simmaco M, Gradini R, Battaglia G, Signore M, Puliti A, Nicoletti F.

Mol Brain. 2013 Nov 19;6:48. doi: 10.1186/1756-6606-6-48.

16.

Analgesic effect of a single preoperative dose of the antibiotic ceftriaxone in humans.

Macaluso A, Bernabucci M, Trabucco A, Ciolli L, Troisi F, Baldini R, Gradini R, Battaglia G, Nicoletti F, Collini S.

J Pain. 2013 Jun;14(6):604-12. doi: 10.1016/j.jpain.2013.01.774.

PMID:
23725677
17.

N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors.

Bernabucci M, Notartomaso S, Zappulla C, Fazio F, Cannella M, Motolese M, Battaglia G, Bruno V, Gradini R, Nicoletti F.

Mol Pain. 2012 Oct 23;8:77. doi: 10.1186/1744-8069-8-77.

18.

Lack or inhibition of dopaminergic stimulation induces a development increase of striatal tyrosine hydroxylase-positive interneurons.

Busceti CL, Bucci D, Molinaro G, Di Pietro P, Zangrandi L, Gradini R, Moratalla R, Battaglia G, Bruno V, Nicoletti F, Fornai F.

PLoS One. 2012;7(9):e44025. doi: 10.1371/journal.pone.0044025. Epub 2012 Sep 18.

19.

Anxiety-like behaviour and associated neurochemical and endocrinological alterations in male pups exposed to prenatal stress.

Laloux C, Mairesse J, Van Camp G, Giovine A, Branchi I, Bouret S, Morley-Fletcher S, Bergonzelli G, Malagodi M, Gradini R, Nicoletti F, Darnaudéry M, Maccari S.

Psychoneuroendocrinology. 2012 Oct;37(10):1646-58. doi: 10.1016/j.psyneuen.2012.02.010. Epub 2012 Mar 22.

PMID:
22444623
20.

Role of the intravitreal growth factors in the pathogenesis of idiopathic epiretinal membrane.

Iannetti L, Accorinti M, Malagola R, Bozzoni-Pantaleoni F, Da Dalt S, Nicoletti F, Gradini R, Traficante A, Campanella M, Pivetti-Pezzi P.

Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5786-9. doi: 10.1167/iovs.10-7116.

PMID:
21693611
21.

The conditioned eyeblink reflex: a potential tool for the detection of cerebellar dysfunction in multiple sclerosis.

Rampello L, Casolla B, Rampello L, Pignatelli M, Battaglia G, Gradini R, Orzi F, Nicoletti F.

Mult Scler. 2011 Oct;17(10):1155-61. doi: 10.1177/1352458511406311. Epub 2011 May 25. Review.

PMID:
21613334
22.

Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced hippocampal damage.

Matrisciano F, Busceti CL, Bucci D, Orlando R, Caruso A, Molinaro G, Cappuccio I, Riozzi B, Gradini R, Motolese M, Caraci F, Copani A, Scaccianoce S, Melchiorri D, Bruno V, Battaglia G, Nicoletti F.

PLoS One. 2011 Jan 27;6(1):e16447. doi: 10.1371/journal.pone.0016447.

23.

Protective role for type-1 metabotropic glutamate receptors against spike and wave discharges in the WAG/Rij rat model of absence epilepsy.

Ngomba RT, Santolini I, Biagioni F, Molinaro G, Simonyi A, van Rijn CM, D'Amore V, Mastroiacovo F, Olivieri G, Gradini R, Ferraguti F, Battaglia G, Bruno V, Puliti A, van Luijtelaar G, Nicoletti F.

Neuropharmacology. 2011 Jun;60(7-8):1281-91. doi: 10.1016/j.neuropharm.2011.01.007. Epub 2011 Jan 26.

PMID:
21277877
24.

Lyrica cures the tenor.

Nicoletti F, Gradini R, Bassi PF, Rampello L.

Clin Neuropharmacol. 2009 Mar-Apr;32(2):119. doi: 10.1097/WNF.0b013e31816b6491. No abstract available.

PMID:
19512967
25.

De novo seven extra repeat expanded mutation in the PRNP gene in an Italian patient with early onset dementia.

Cannella M, Martino T, Simonelli M, Ciammola A, Gradini R, Ciarmiello A, Gianfrancesco F, Squitieri F.

BMJ Case Rep. 2009;2009. pii: bcr08.2008.0711. doi: 10.1136/bcr.08.2008.0711. Epub 2009 Feb 2.

26.

Switch in the expression of mGlu1 and mGlu5 metabotropic glutamate receptors in the cerebellum of mice developing experimental autoimmune encephalomyelitis and in autoptic cerebellar samples from patients with multiple sclerosis.

Fazio F, Notartomaso S, Aronica E, Storto M, Battaglia G, Vieira E, Gatti S, Bruno V, Biagioni F, Gradini R, Nicoletti F, Di Marco R.

Neuropharmacology. 2008 Sep;55(4):491-9. doi: 10.1016/j.neuropharm.2008.06.066. Epub 2008 Jul 8.

PMID:
18619983
27.

Prenatal restraint stress generates two distinct behavioral and neurochemical profiles in male and female rats.

Zuena AR, Mairesse J, Casolini P, Cinque C, Alemà GS, Morley-Fletcher S, Chiodi V, Spagnoli LG, Gradini R, Catalani A, Nicoletti F, Maccari S.

PLoS One. 2008 May 14;3(5):e2170. doi: 10.1371/journal.pone.0002170.

28.

Enhanced tau phosphorylation in the hippocampus of mice treated with 3,4-methylenedioxymethamphetamine ("Ecstasy").

Busceti CL, Biagioni F, Riozzi B, Battaglia G, Storto M, Cinque C, Molinaro G, Gradini R, Caricasole A, Canudas AM, Bruno V, Nicoletti F, Fornai F.

J Neurosci. 2008 Mar 19;28(12):3234-45. doi: 10.1523/JNEUROSCI.0159-08.2008.

29.

GD3 nuclear localization after apoptosis induction in HUT-78 cells.

Tempera I, Buchetti B, Lococo E, Gradini R, Mastronardi A, Mascellino MT, Sale P, Mosca L, d'Erme M, Lenti L.

Biochem Biophys Res Commun. 2008 Apr 11;368(3):495-500. doi: 10.1016/j.bbrc.2007.12.196. Epub 2008 Feb 7.

PMID:
18261989
30.

De novo seven extra repeat expanded mutation in the PRNP gene in an Italian patient with early onset dementia.

Cannella M, Martino T, Simonelli M, Ciammola A, Gradini R, Ciarmiello A, Gianfrancesco F, Squitieri F.

J Neurol Neurosurg Psychiatry. 2007 Dec;78(12):1411-3. Epub 2007 Aug 6. No abstract available.

31.

Metabotropic glutamate receptors: beyond the regulation of synaptic transmission.

Nicoletti F, Battaglia G, Storto M, Ngomba RT, Iacovelli L, Arcella A, Gradini R, Sale P, Rampello L, De Vita T, Di Marco R, Melchiorri D, Bruno V.

Psychoneuroendocrinology. 2007 Aug;32 Suppl 1:S40-5. Epub 2007 Jul 24. Review.

PMID:
17651904
32.

Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy.

Busceti CL, Biagioni F, Aronica E, Riozzi B, Storto M, Battaglia G, Giorgi FS, Gradini R, Fornai F, Caricasole A, Nicoletti F, Bruno V.

Epilepsia. 2007 Apr;48(4):694-705.

33.

Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.

Verani R, Cappuccio I, Spinsanti P, Gradini R, Caruso A, Magnotti MC, Motolese M, Nicoletti F, Melchiorri D.

J Neurochem. 2007 Jan;100(1):242-50. Epub 2006 Oct 25.

34.

Context-dependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors.

Cappuccio I, Verani R, Spinsanti P, Niccolini C, Gradini R, Costantino S, Nicoletti F, Melchiorri D.

Neuropharmacology. 2006 Sep;51(3):606-11. Epub 2006 Jun 27.

PMID:
16806298
35.

Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells.

Sottocornola E, Misasi R, Mattei V, Ciarlo L, Gradini R, Garofalo T, Berra B, Colombo I, Sorice M.

FEBS J. 2006 Apr;273(8):1821-30.

36.

Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors.

Storto M, Capobianco L, Battaglia G, Molinaro G, Gradini R, Riozzi B, Di Mambro A, Mitchell KJ, Bruno V, Vairetti MP, Rutter GA, Nicoletti F.

Mol Pharmacol. 2006 Apr;69(4):1234-41. Epub 2006 Jan 19.

PMID:
16424079
37.

Huntingtin fragmentation and increased caspase 3, 8 and 9 activities in lymphoblasts with heterozygous and homozygous Huntington's disease mutation.

Maglione V, Cannella M, Gradini R, Cislaghi G, Squitieri F.

Mech Ageing Dev. 2006 Feb;127(2):213-6. Epub 2005 Nov 10.

PMID:
16289252
38.

C3-induced 3LL cell proliferation is mediated by C kinase.

Longo A, Gradini R, Mattei V, Morgante E, Sale P, Tafani M, Lipari M, Pontieri GM, Russo MA.

J Cell Biochem. 2005 Feb 15;94(3):635-44.

PMID:
15547948
39.

Mouse hepatocytes lacking mGlu5 metabotropic glutamate receptors are less sensitive to hypoxic damage.

Storto M, Battaglia G, Gradini R, Bruno V, Nicoletti F, Vairetti M.

Eur J Pharmacol. 2004 Aug 16;497(1):25-7.

PMID:
15321731
40.

Activation of Fas receptor is required for the increased formation of the disialoganglioside GD3 in cultured cerebellar granule cells committed to apoptotic death.

Castiglione M, Spinsanti P, Iacovelli L, Lenti L, Martini F, Gradini R, Di Giorgi Gerevini V, Caricasole A, Caruso A, De Maria R, Nicoletti F, Melchiorri D.

Neuroscience. 2004;126(4):889-98.

PMID:
15207324
41.

The mGlu5 metabotropic glutamate receptor is expressed in zones of active neurogenesis of the embryonic and postnatal brain.

Di Giorgi Gerevini VD, Caruso A, Cappuccio I, Ricci Vitiani L, Romeo S, Della Rocca C, Gradini R, Melchiorri D, Nicoletti F.

Brain Res Dev Brain Res. 2004 May 19;150(1):17-22.

PMID:
15126034
42.

Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes.

Anastasi E, Campese AF, Bellavia D, Bulotta A, Balestri A, Pascucci M, Checquolo S, Gradini R, Lendahl U, Frati L, Gulino A, Di Mario U, Screpanti I.

J Immunol. 2003 Nov 1;171(9):4504-11.

43.

Subcellular localization of the BRCA1 gene product in mitotic cells.

Lotti LV, Ottini L, D'Amico C, Gradini R, Cama A, Belleudi F, Frati L, Torrisi MR, Mariani-Costantini R.

Genes Chromosomes Cancer. 2002 Nov;35(3):193-203.

PMID:
12353262
44.

REN: a novel, developmentally regulated gene that promotes neural cell differentiation.

Gallo R, Zazzeroni F, Alesse E, Mincione C, Borello U, Buanne P, D'Eugenio R, Mackay AR, Argenti B, Gradini R, Russo MA, Maroder M, Cossu G, Frati L, Screpanti I, Gulino A.

J Cell Biol. 2002 Aug 19;158(4):731-40. Epub 2002 Aug 19.

45.

Native group-III metabotropic glutamate receptors are coupled to the mitogen-activated protein kinase/phosphatidylinositol-3-kinase pathways.

Iacovelli L, Bruno V, Salvatore L, Melchiorri D, Gradini R, Caricasole A, Barletta E, De Blasi A, Nicoletti F.

J Neurochem. 2002 Jul;82(2):216-23.

46.

An early increase in the disialoganglioside GD3 contributes to the development of neuronal apoptosis in culture.

Melchiorri D, Martini F, Lococo E, Gradini R, Barletta E, De Maria R, Caricasole A, Nicoletti F, Lenti L.

Cell Death Differ. 2002 Jun;9(6):609-15.

47.

Beta-amyloid-induced synthesis of the ganglioside GD3 is a requisite for cell cycle reactivation and apoptosis in neurons.

Copani A, Melchiorri D, Caricasole A, Martini F, Sale P, Carnevale R, Gradini R, Sortino MA, Lenti L, De Maria R, Nicoletti F.

J Neurosci. 2002 May 15;22(10):3963-8.

48.

Evidence for anticoagulant activity and beta2-GPI accumulation in late endosomes of endothelial cells induced by anti-LBPA antibodies.

Sorice M, Ferro D, Misasi R, Pittoni V, Longo A, Circella A, Garofalo T, Gradini R, Violi F, Gruenberg J, Valesini G.

Thromb Haemost. 2002 Apr;87(4):735-41.

PMID:
12008959
49.

Evidence for cell surface association between CXCR4 and ganglioside GM3 after gp120 binding in SupT1 lymphoblastoid cells.

Sorice M, Garofalo T, Misasi R, Longo A, Mattei V, Sale P, Dolo V, Gradini R, Pavan A.

FEBS Lett. 2001 Sep 28;506(1):55-60.

50.

GD3 glycosphingolipid contributes to Fas-mediated apoptosis via association with ezrin cytoskeletal protein.

Giammarioli AM, Garofalo T, Sorice M, Misasi R, Gambardella L, Gradini R, Fais S, Pavan A, Malorni W.

FEBS Lett. 2001 Sep 28;506(1):45-50. Erratum in: FEBS Lett 2001 Nov 23;508(3):494.

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