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Items: 17


An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression.

Albanese SK, Parton DL, Işık M, Rodríguez-Laureano L, Hanson SM, Behr JM, Gradia S, Jeans C, Levinson NM, Seeliger MA, Chodera JD.

Biochemistry. 2018 Aug 7;57(31):4675-4689. doi: 10.1021/acs.biochem.7b01081. Epub 2018 Jul 26.


MacroBac: New Technologies for Robust and Efficient Large-Scale Production of Recombinant Multiprotein Complexes.

Gradia SD, Ishida JP, Tsai MS, Jeans C, Tainer JA, Fuss JO.

Methods Enzymol. 2017;592:1-26. doi: 10.1016/bs.mie.2017.03.008. Epub 2017 May 15.


Mapping the genomic landscape of CRISPR-Cas9 cleavage.

Cameron P, Fuller CK, Donohoue PD, Jones BN, Thompson MS, Carter MM, Gradia S, Vidal B, Garner E, Slorach EM, Lau E, Banh LM, Lied AM, Edwards LS, Settle AH, Capurso D, Llaca V, Deschamps S, Cigan M, Young JK, May AP.

Nat Methods. 2017 Jun;14(6):600-606. doi: 10.1038/nmeth.4284. Epub 2017 May 1.


DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.

van Overbeek M, Capurso D, Carter MM, Thompson MS, Frias E, Russ C, Reece-Hoyes JS, Nye C, Gradia S, Vidal B, Zheng J, Hoffman GR, Fuller CK, May AP.

Mol Cell. 2016 Aug 18;63(4):633-646. doi: 10.1016/j.molcel.2016.06.037. Epub 2016 Aug 4.


Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization.

Totir M, Echols N, Nanao M, Gee CL, Moskaleva A, Gradia S, Iavarone AT, Berger JM, May AP, Zubieta C, Alber T.

PLoS One. 2012;7(2):e32498. doi: 10.1371/journal.pone.0032498. Epub 2012 Feb 29.


Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).

Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20473-8. doi: 10.1073/pnas.1116821108. Epub 2011 Dec 1.


The MukF subunit of Escherichia coli condensin: architecture and functional relationship to kleisins.

Fennell-Fezzie R, Gradia SD, Akey D, Berger JM.

EMBO J. 2005 Jun 1;24(11):1921-30. Epub 2005 May 19.


Signaling mismatch repair: the mechanics of an adenosine-nucleotide molecular switch.

Fishel R, Acharya S, Berardini M, Bocker T, Charbonneau N, Cranston A, Gradia S, Guerrette S, Heinen CD, Mazurek A, Snowden T, Schmutte C, Shim KS, Tombline G, Wilson T.

Cold Spring Harb Symp Quant Biol. 2000;65:217-24. Review. No abstract available.


The role of mismatched nucleotides in activating the hMSH2-hMSH6 molecular switch.

Gradia S, Acharya S, Fishel R.

J Biol Chem. 2000 Feb 11;275(6):3922-30.


hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA.

Gradia S, Subramanian D, Wilson T, Acharya S, Makhov A, Griffith J, Fishel R.

Mol Cell. 1999 Feb;3(2):255-61.


The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch.

Gradia S, Acharya S, Fishel R.

Cell. 1997 Dec 26;91(7):995-1005.


hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.

Acharya S, Wilson T, Gradia S, Kane MF, Guerrette S, Marsischky GT, Kolodner R, Fishel R.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13629-34.


Expression of a 32 kDa protein in rat mammary tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide.

Ronai Z, Polotskaya A, Gradia S, Amin S, Hecht SS.

Int J Cancer. 1996 Jul 3;67(1):124-8.


Contrasting incidence of ras mutations in rat mammary and mouse skin tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide.

Ronai ZA, Gradia S, el-Bayoumy K, Amin S, Hecht SS.

Carcinogenesis. 1994 Oct;15(10):2113-6.


Detection of k-ras mutation in normal and malignant colonic tissues by an enriched PCR method.

Ronai Z, Luo F, Gradia S, Hart W, Butler R.

Int J Oncol. 1994 Feb;4(2):391-6.


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