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Items: 47

1.

Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain.

Peng Y, Zhang X, Zhang T, Grace PM, Li H, Wang Y, Li H, Chen H, Watkins LR, Hutchinson MR, Yin H, Wang X.

Brain Behav Immun. 2019 Nov;82:432-444. doi: 10.1016/j.bbi.2019.09.013. Epub 2019 Sep 19.

PMID:
31542403
2.

Sham surgeries for central and peripheral neural injuries persistently enhance pain-avoidance behavior as revealed by an operant conflict test.

Odem MA, Lacagnina MJ, Katzen SL, Li J, Spence EA, Grace PM, Walters ET.

Pain. 2019 Nov;160(11):2440-2455. doi: 10.1097/j.pain.0000000000001642.

PMID:
31323014
3.

Oxycodone, fentanyl, and morphine amplify established neuropathic pain in male rats.

Green-Fulgham SM, Ball JB, Kwilasz AJ, Fabisiak T, Maier SF, Watkins LR, Grace PM.

Pain. 2019 Nov;160(11):2634-2640. doi: 10.1097/j.pain.0000000000001652.

PMID:
31299018
4.

Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling.

Zhang X, Peng Y, Grace PM, Metcalf MD, Kwilasz AJ, Wang Y, Zhang T, Wu S, Selfridge BR, Portoghese PS, Rice KC, Watkins LR, Hutchinson MR, Wang X.

FASEB J. 2019 Aug;33(8):9577-9587. doi: 10.1096/fj.201900173RRR. Epub 2019 Jun 4.

PMID:
31162938
5.

A backbone for reverse-translation: Evidence for neuroinflammation in patients with low back pain.

Grace PM.

Brain Behav Immun. 2019 Jan;75:8-9. doi: 10.1016/j.bbi.2018.11.001. Epub 2018 Nov 7. No abstract available.

PMID:
30414443
6.

MicroRNA-124 and microRNA-146a both attenuate persistent neuropathic pain induced by morphine in male rats.

Grace PM, Strand KA, Galer EL, Maier SF, Watkins LR.

Brain Res. 2018 Aug 1;1692:9-11. doi: 10.1016/j.brainres.2018.04.038. Epub 2018 May 1.

7.

Repeated Morphine Prolongs Postoperative Pain in Male Rats.

Grace PM, Galer EL, Strand KA, Corrigan K, Berkelhammer D, Maier SF, Watkins LR.

Anesth Analg. 2019 Jan;128(1):161-167. doi: 10.1213/ANE.0000000000003345.

PMID:
29596097
8.

DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats.

Grace PM, Wang X, Strand KA, Baratta MV, Zhang Y, Galer EL, Yin H, Maier SF, Watkins LR.

Exp Neurol. 2018 Jun;304:125-131. doi: 10.1016/j.expneurol.2018.03.005. Epub 2018 Mar 9.

9.

Toll-like receptors and their role in persistent pain.

Lacagnina MJ, Watkins LR, Grace PM.

Pharmacol Ther. 2018 Apr;184:145-158. doi: 10.1016/j.pharmthera.2017.10.006. Epub 2017 Oct 4. Review.

10.

Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats.

Grace PM, Strand KA, Galer EL, Rice KC, Maier SF, Watkins LR.

Brain Behav Immun. 2018 Aug;72:45-50. doi: 10.1016/j.bbi.2017.08.018. Epub 2017 Aug 30.

11.

Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats.

Lacagnina MJ, Kopec AM, Cox SS, Hanamsagar R, Wells C, Slade S, Grace PM, Watkins LR, Levin ED, Bilbo SD.

Neuropsychopharmacology. 2017 Oct;42(11):2128-2140. doi: 10.1038/npp.2017.82. Epub 2017 Apr 24.

12.

Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia.

Lewis SS, Grace PM, Hutchinson MR, Maier SF, Watkins LR.

Brain Behav Immun. 2017 Aug;64:59-64. doi: 10.1016/j.bbi.2016.12.004. Epub 2016 Dec 18.

13.

Nitroxidative Signaling Mechanisms in Pathological Pain.

Grace PM, Gaudet AD, Staikopoulos V, Maier SF, Hutchinson MR, Salvemini D, Watkins LR.

Trends Neurosci. 2016 Dec;39(12):862-879. doi: 10.1016/j.tins.2016.10.003. Epub 2016 Nov 12. Review.

14.

HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia.

Das N, Dewan V, Grace PM, Gunn RJ, Tamura R, Tzarum N, Watkins LR, Wilson IA, Yin H.

Cell Rep. 2016 Oct 18;17(4):1128-1140. doi: 10.1016/j.celrep.2016.09.076.

15.

Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain.

Dodds KN, Beckett EA, Evans SF, Grace PM, Watkins LR, Hutchinson MR.

Transl Psychiatry. 2016 Sep 13;6(9):e888. doi: 10.1038/tp.2016.168. Review.

16.

Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury.

Ellis A, Grace PM, Wieseler J, Favret J, Springer K, Skarda B, Ayala M, Hutchinson MR, Falci S, Rice KC, Maier SF, Watkins LR.

Brain Behav Immun. 2016 Nov;58:348-356. doi: 10.1016/j.bbi.2016.08.004. Epub 2016 Aug 9.

17.

Prior voluntary wheel running attenuates neuropathic pain.

Grace PM, Fabisiak TJ, Green-Fulgham SM, Anderson ND, Strand KA, Kwilasz AJ, Galer EL, Walker FR, Greenwood BN, Maier SF, Fleshner M, Watkins LR.

Pain. 2016 Sep;157(9):2012-23. doi: 10.1097/j.pain.0000000000000607.

18.

Neuropeptide substance P and the immune response.

Mashaghi A, Marmalidou A, Tehrani M, Grace PM, Pothoulakis C, Dana R.

Cell Mol Life Sci. 2016 Nov;73(22):4249-4264. doi: 10.1007/s00018-016-2293-z. Epub 2016 Jun 17. Review.

19.

Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation.

Grace PM, Strand KA, Galer EL, Urban DJ, Wang X, Baratta MV, Fabisiak TJ, Anderson ND, Cheng K, Greene LI, Berkelhammer D, Zhang Y, Ellis AL, Yin HH, Campeau S, Rice KC, Roth BL, Maier SF, Watkins LR.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3441-50. doi: 10.1073/pnas.1602070113. Epub 2016 May 31.

20.

Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy.

Grace PM, Loram LC, Christianson JP, Strand KA, Flyer-Adams JG, Penzkover KR, Forsayeth JR, van Dam AM, Mahoney MJ, Maier SF, Chavez RA, Watkins LR.

Brain Behav Immun. 2017 Jan;59:49-54. doi: 10.1016/j.bbi.2016.05.012. Epub 2016 May 14.

21.

Learning the lessons of networking.

Grace PM.

Science. 2016 May 6;352(6286):738. doi: 10.1126/science.352.6286.738. No abstract available.

PMID:
27151872
22.

Reactive aldehydes: a new player in inflammatory pain.

Galer EL, Grace PM.

Ann Transl Med. 2015 May;3(Suppl 1):S23. doi: 10.3978/j.issn.2305-5839.2015.03.27. No abstract available.

23.

Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists.

Selfridge BR, Wang X, Zhang Y, Yin H, Grace PM, Watkins LR, Jacobson AE, Rice KC.

J Med Chem. 2015 Jun 25;58(12):5038-52. doi: 10.1021/acs.jmedchem.5b00426. Epub 2015 Jun 5.

24.

Opioid-induced central immune signaling: implications for opioid analgesia.

Grace PM, Maier SF, Watkins LR.

Headache. 2015 Apr;55(4):475-89. doi: 10.1111/head.12552. Epub 2015 Mar 31. Review.

25.

(+)-Naltrexone is neuroprotective and promotes alternative activation in the mouse hippocampus after cardiac arrest/cardiopulmonary resuscitation.

Grace PM, Shimizu K, Strand KA, Rice KC, Deng G, Watkins LR, Herson PS.

Brain Behav Immun. 2015 Aug;48:115-22. doi: 10.1016/j.bbi.2015.03.005. Epub 2015 Mar 13.

26.

Pioglitazone rapidly reduces neuropathic pain through astrocyte and nongenomic PPARĪ³ mechanisms.

Griggs RB, Donahue RR, Morgenweck J, Grace PM, Sutton A, Watkins LR, Taylor BK.

Pain. 2015 Mar;156(3):469-82. doi: 10.1097/01.j.pain.0000460333.79127.be.

27.

The therapeutic potential of interleukin-10 in neuroimmune diseases.

Kwilasz AJ, Grace PM, Serbedzija P, Maier SF, Watkins LR.

Neuropharmacology. 2015 Sep;96(Pt A):55-69. doi: 10.1016/j.neuropharm.2014.10.020. Epub 2014 Nov 4. Review.

28.

Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae.

Grace PM, Ramos KM, Rodgers KM, Wang X, Hutchinson MR, Lewis MT, Morgan KN, Kroll JL, Taylor FR, Strand KA, Zhang Y, Berkelhammer D, Huey MG, Greene LI, Cochran TA, Yin H, Barth DS, Johnson KW, Rice KC, Maier SF, Watkins LR.

Neuroscience. 2014 Nov 7;280:299-317. doi: 10.1016/j.neuroscience.2014.09.020. Epub 2014 Sep 18.

29.

Sex differences in mechanical allodynia: how can it be preclinically quantified and analyzed?

Nicotra L, Tuke J, Grace PM, Rolan PE, Hutchinson MR.

Front Behav Neurosci. 2014 Feb 13;8:40. doi: 10.3389/fnbeh.2014.00040. eCollection 2014.

30.

Pathological pain and the neuroimmune interface.

Grace PM, Hutchinson MR, Maier SF, Watkins LR.

Nat Rev Immunol. 2014 Apr;14(4):217-31. doi: 10.1038/nri3621. Epub 2014 Feb 28. Review.

31.

Immune priming and experimental glaucoma: the effect of prior systemic lipopolysaccharide challenge on tissue outcomes after optic nerve injury.

Narayan DS, Casson RJ, Ebneter A, Chidlow G, Grace PM, Hutchinson MR, Wood JP.

Clin Exp Ophthalmol. 2014 Aug;42(6):539-54. doi: 10.1111/ceo.12289. Epub 2014 Jan 23.

PMID:
24373007
32.

Suppression of voluntary wheel running in rats is dependent on the site of inflammation: evidence for voluntary running as a measure of hind paw-evoked pain.

Grace PM, Strand KA, Maier SF, Watkins LR.

J Pain. 2014 Feb;15(2):121-8. doi: 10.1016/j.jpain.2013.10.001. Epub 2013 Oct 12.

33.

TLR 2 and 4 responsiveness from isolated peripheral blood mononuclear cells from rats and humans as potential chronic pain biomarkers.

Kwok YH, Tuke J, Nicotra LL, Grace PM, Rolan PE, Hutchinson MR.

PLoS One. 2013 Oct 30;8(10):e77799. doi: 10.1371/journal.pone.0077799. eCollection 2013.

34.

Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain.

Wang X, Grace PM, Pham MN, Cheng K, Strand KA, Smith C, Li J, Watkins LR, Yin H.

FASEB J. 2013 Jul;27(7):2713-22. doi: 10.1096/fj.12-222992. Epub 2013 Apr 8.

35.

Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy.

Loram LC, Grace PM, Strand KA, Taylor FR, Ellis A, Berkelhammer D, Bowlin M, Skarda B, Maier SF, Watkins LR.

Brain Behav Immun. 2012 Nov;26(8):1256-64. doi: 10.1016/j.bbi.2012.08.003. Epub 2012 Aug 10.

36.

Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model.

Grace PM, Hurley D, Barratt DT, Tsykin A, Watkins LR, Rolan PE, Hutchinson MR.

J Neurochem. 2012 Sep;122(5):976-94. doi: 10.1111/j.1471-4159.2012.07833.x. Epub 2012 Jul 9.

37.

The anatomical distribution of trigeminal neuralgia: a perspective and future directions.

Grace PM.

Anesth Pain Med. 2012 Winter;1(3):212-3. doi: 10.5812/kowsar.22287523.3641. Epub 2012 Jan 1. No abstract available.

38.

Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia.

Hutchinson MR, Shavit Y, Grace PM, Rice KC, Maier SF, Watkins LR.

Pharmacol Rev. 2011 Sep;63(3):772-810. doi: 10.1124/pr.110.004135. Epub 2011 Jul 13. Review.

39.

Peripheral immune contributions to the maintenance of central glial activation underlying neuropathic pain.

Grace PM, Rolan PE, Hutchinson MR.

Brain Behav Immun. 2011 Oct;25(7):1322-32. doi: 10.1016/j.bbi.2011.04.003. Epub 2011 Apr 7. Review.

PMID:
21496480
40.

Adoptive transfer of peripheral immune cells potentiates allodynia in a graded chronic constriction injury model of neuropathic pain.

Grace PM, Hutchinson MR, Bishop A, Somogyi AA, Mayrhofer G, Rolan PE.

Brain Behav Immun. 2011 Mar;25(3):503-13. doi: 10.1016/j.bbi.2010.11.018. Epub 2010 Dec 4.

PMID:
21134441
41.

A novel animal model of graded neuropathic pain: utility to investigate mechanisms of population heterogeneity.

Grace PM, Hutchinson MR, Manavis J, Somogyi AA, Rolan PE.

J Neurosci Methods. 2010 Oct 30;193(1):47-53. doi: 10.1016/j.jneumeth.2010.08.025. Epub 2010 Sep 9.

PMID:
20817038
42.

Utility of saccadic eye movement analysis as an objective biomarker to detect the sedative interaction between opioids and sleep deprivation in opioid-naive and opioid-tolerant populations.

Grace PM, Stanford T, Gentgall M, Rolan PE.

J Psychopharmacol. 2010 Nov;24(11):1631-40. doi: 10.1177/0269881109352704. Epub 2010 Feb 8.

PMID:
20142307
43.

Living with lichen planopilaris.

Grace PM.

Dermatol Nurs. 2007 Apr;19(2):184-5. No abstract available.

PMID:
17526308
44.

Quantitative exposure assessment for the combustion of meat and bone meal derived from specified risk material in the context of BSE in Ireland.

Cummins EJ, Grace PM, Fry DJ, McDonnell KP, Colgan SF, Ward SM.

J Agric Saf Health. 2002 Nov;8(4):365-83.

PMID:
12549242
45.
46.

Results of simple aspiration of pneumothoraces.

Archer GJ, Hamilton AA, Upadhyay R, Finlay M, Grace PM.

Br J Dis Chest. 1985 Apr;79(2):177-82.

PMID:
3986122
47.

Antituberculous drug doses in children.

Archer GJ, Henderson C, Grace PM.

Lancet. 1983 Oct 29;2(8357):1025-6. No abstract available.

PMID:
6138567

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